Biomechanics and Biotransport Commons^™

A Numerical Analysis Of The Effects Of Wing Kinematics On Flapping Wing Aeroacoustics, Kabilan Nedunchezian, Chang-Kwon Kang, Hikaru Aono

PRC-Affiliated Research

Despite the recent interest in flapping wing aerodynamics, the aerodynamic sound generation mechanism of a flapping wing is inadequately understood. In this paper, the interplay between the wing motion, resulting unsteady aerodynamics, and aeroacoustics of a flapping wing flyer is investigated. The wing motion is varied in terms of the flapping amplitude, pitching amplitude, and the phase difference between flap and pitch. The unsteady flow around the flapping wing is numerically calculated using a well-validated Navier-Stokes equation solver. Acoustic pressures are computed using the Ffowcs-Williams-Hawkings equation in a three-dimensional space at varying distances from the wing. Two main sound generation …

Determining The Relationship Between Walking Activity And Inter-Day Patterns In Stroke Survivors, Sydney Andreasen

UNO Student Research and Creative Activity Fair

Populations that have suffered from stroke are generally less active than people of otherwise similar demographics and are more susceptible to further health problems, such as another stroke. This study seeks to assess the validity of a treatment that encourages stroke survivors to walk more steps each day, in order to improve their active abilities and become less idle by establishing motivation for activity and therefore, also establishing patterns in the distribution of that activity throughout a stroke survivor’s day. 172 subjects (6 months post-stroke) have participated in a step activity monitoring program to record steps taken using wearable pedometers. …

Intensity And Pattern Of Daily Physical Activity Of Claudicating Patients, Cody Anderson

UNO Student Research and Creative Activity Fair

file:///C:/Users/codya/Desktop/Cody%20et%20al_2019_Human%20Movement%20Variability%20Conference.pdf

Gait Alterations After Anterior Cruciate Ligament Injury And Implications For Return-To-Play Testing, Lindsey Remski

UNO Student Research and Creative Activity Fair

Introduction: Reoccurring injury to the anterior cruciate ligament (ACL) is a major problem for individuals who undergo ACL reconstructive surgery despite them meeting current requirements for return-to-play. Previous studies have found alterations in gait kinetics and kinematics of ACL deficient and ACL reconstruction patients. It is unknown if gait parameters, such as peak joint angles and moments, provide different information about patient function from what is provided by return-to-play outcomes. Purpose: To assess the relationships between peak joint angles, peak joint moments, and return-to-play outcomes for individuals with ACL injury. Methods: 6 subjects (3 ACL reconstruction, 3 ACL deficient) performed …

Visual Contributions To Balance Control During Gait, Kyle Brozek

UNO Student Research and Creative Activity Fair

We propose to isolate the contributions of continuous OF to the orthogonal relationship between balance and gait control during treadmill walking using a series of conditions. Manipulating the direction of OF using a CAREN (Motek Medical, Amsterdam, Netherlands) virtual reality treadmill environment will isolate these visual contributions in human subjects as they walk. We plan to tease out the effect of OF direction on the relationship between gait and balance control by having healthy young adults perform a series of treadmill walking trials while immersed in a VR environment. This will be done by manipulating the direction of walking and …

Effects Of A Passive Dynamic Lower-Leg Exoskeleton During Walking, Blake Beier

UNO Student Research and Creative Activity Fair

The ankle joint is one of the most important joints during walking. If the muscles surrounding the ankle are weak, there are reductions in the ability to generate appropriate torques and powers at the ankle. This leads to slower self-selected walking speeds, which correlate with poor physical functioning, more disabilities, increased hospitalization visits and costs, and even mortality. Because of this, many orthotic and exoskeletal devices have been created to restore proper ankle function by promoting ankle plantar flexion. Utilizing 3D printing and an extension spring, we created an easily accessible, reproducible, and modifiable exoskeleton that has the potential to …

Gait Alterations In Peripheral Arterial Disease Are Not Worsened By The Presence Of Diabetes, Hafizur Rahman

UNO Student Research and Creative Activity Fair

Peripheral arterial disease (PAD) is a vascular disease where atherosclerotic blockages restrict blood flow to muscles in the lower extremities. Diabetes is a common co-morbid condition in PAD and has been shown to increase the risk of lower extremity amputation compared to PAD without diabetes. Although there is a clear pathological relationship between diabetes and PAD, the gait mechanics involved remain indistinct. Therefore, the purpose of this study was to determine whether the presence of diabetes in addition to PAD results in greater functional impairment during ambulation. Twenty-three subjects with PAD and twelve controls consented to participate in the research. …

Collision Work Performed By Patients With Peripheral Artery Disease, Alex Dzewaltowski, Sara A. Myers, Jason M. Johanning, Iraklis I. Pipinos

UNO Student Research and Creative Activity Fair

The goal of this study was to assess the differences in collision work performed by healthy, aged-matched controls compared to patients with peripheral artery disease (PAD) to provide foundations for an eventual exoskeleton design. Collision work is energy dissipated into the surrounding environment from impact, in this study’s case, upon heel strike. When designing an exoskeleton for patients with PAD, harvesting energy lost to collision work could be a valuable mechanism to improve walking performance. Devices designed to utilize the normally dissipated energy for assisting propulsion to improve walking performance are under-explored [1, 2]. The purpose of this study was …

Bimanual Coordination Assessment Using Prosthetic Simulators, Chris Copeland

UNO Student Research and Creative Activity Fair

There were a total of 1.6 million people living with loss of a limb in 2005. This number is projected to double to 3.6 million by 2050 [1]. While prosthetics aim to enhance the function of these individuals, it is estimated that 45% of pediatric prosthetic users reject their prosthesis [2]. The literature which describes the motor control mechanisms of prosthetic use is sparse and often low-powered due to inadequate number of subjects. However, prosthetic simulators may be a solution to chronically low-powered prosthetic studies by serving as functional homologues. The purpose of this investigation was to determine the efficacy …

The Energy Paradox Of The Ankle-Foot Complex During Human Walking, Nikolaos Papachatzis, Kota Takahashi

UNO Student Research and Creative Activity Fair

Flexor hallucis longus (FHL) is a multiarticular muscle that possesses the potential to alter foot’s functional and mechanical behavior, since it performs multiple significant functions during walking (e.g supports the medial longitudinal arch of the foot).The purpose of this study was to determine if the functional changes of the FHL are associated with the foot’s adaptations to the mechanical demands of walking. Backward walking is an experimental method capable of altering how the forces propagate underneath the foot and disrupting the mechanical function of the FHL muscle. We hypothesized that: (1) the muscle activity of the FHL will increase during …

Simulation Of Joint Contact Forces In Total Knee Arthroplasty Patients Using Opensim, Benjamin Frazier

UNO Student Research and Creative Activity Fair

The occurrence of Total Knee Arthroplasty (TKA) is projected to increase markedly in the coming decade, and a better method of rehabilitating TKA patients is becoming necessary. Rehabilitation of these patients is of utmost importance such that patients are capable of using the limb effectively. Focus towards improving the rehabilitation of patients that have undergone TKA operations requires a metric for comparison of performance between control groups and experimental groups. Joint contact forces (JCF) calculated via simulation in OpenSim using Motion Capture and Force Plate data provide effective means comparing these groups. Subjects are outfitted with a marker set and …

A Comparative Study For Feature Selection Algorithms To Analyze Gait Patterns For Health Purposes, Donovan Orn

UNO Student Research and Creative Activity Fair

A Comparative Study for Feature Selection Algorithms to Analyze Gait Patterns for Healthcare Purposes

Donovan Orn

Abstract

With the explosive use of wearable devices, there is an urgent need to find ways to utilize the data collected by such devices. In many cases, wearable devices contain accelerometers that collected different types of data. It is not always clear which data points can be used to extract information that can be used to provide useful knowledge about the health of the individuals. In this study, we proposed to research, implement, and comparing various feature selection techniques used for analyzing on gait …

Fluid Delivery System For A Cell Culture On A Microfluidic Chip, Austin J. Roeder, Colleen A. Richards, Emily A. Matteson

Biomedical Engineering

This project report provides a description of the progress made in the development of a fluid delivery system for a microfluidic cell culture on a chip. The system is intended to be used in a humidified incubator in a university laboratory and the fluid delivery system is required to exist and operate within that incubator for extended periods of time. Therefore, the system will be gravity-driven and contain no electronic components. The key specification of the system is to provide fluid flow at a constant velocity.

After manufacturing and testing the device, all specifications were met except for the fluid …

Hard, Soft And Off-The-Shelf Foot Orthoses And Their Effect On The Angle Of The Medial Longitudinal Arch: A Biplane Fluoroscopy Study, Megan E.R. Balsdon, Colin E. Dombroski, Kristen Bushey, Thomas Jenkyn

Mechanical and Materials Engineering Publications

Background: Foot orthoses have proven to be effective for conservative management of various pathologies. Pathologies of the lower limb can be caused by abnormal biomechanics such as abnormal foot structure and alignment, leading to inadequate support. Objectives: To compare biomechanical effects of different foot orthoses on the medial longitudinal arch (MLA) during dynamic gait using skeletal kinematics. Study Design: Prospective, cross-sectional study design. Methods: The MLA angle was measured for 12 participants among three groups: pes planus, pes cavus and normal arch. Five conditions were compared: three orthotic devices (hard custom foot orthosis (CFO), soft CFO, and off-the-shelf Barefoot Science©), …

Quantification Of Myocardial Mechanics In Left Ventricles Under Inotropic Stimulation And In Healthy Right Ventricles Using 3d Dense Cmr, Zhan-Qiu Liu

Theses and Dissertations--Mechanical Engineering

Statistical data from clinical studies indicate that the death rate caused by heart disease has decreased due to an increased use of evidence-based medical therapies. This includes the use of magnetic resonance imaging (MRI), which is one of the most common non-invasive approaches in evidence-based health care research. In the current work, I present 3D Lagrangian strains and torsion in the left ventricle of healthy and isoproterenol-stimulated rats, which were investigated using Displacement ENcoding with Stimulated Echoes (DENSE) cardiac magnetic resonance (CMR) imaging. With the implementation of the 12-segment model, a detailed profile of regional cardiac mechanics was reconstructed for …

The Role Of Kras In Mechanosensing In Non-Small Cell Lung Cancer, Krista M. Powell

Theses and Dissertations

Lung cancer is the number one cause of cancer related death worldwide, with more than 1.6 million fatalities each year. Non-small cell lung cancer (NSCLC) accounts for 80-85% of all lung cancers, with KRAS being one of the most prevalent oncogenic driver mutations. Therapeutic approaches for KRAS-mutated NSCLC have been extensively explored due to the US National Cancer Institute RAS Initiative, but methods of directly targeting KRAS or downstream effectors, such as MEK, still have poor results. Previous reports have shown that KRAS-mutated NSCLC activate distinct receptor tyrosine kinases (RTKs) depending on the epithelial or mesenchymal state. Epithelial-to-mesenchymal transition (EMT) …

Thenar Muscle And Transverse Carpal Ligament Relationship, Jeremy Granieri Loss

ETD Archive

The transverse carpal ligament (TCL) acts as a partial origin for the thenar muscles (abductor pollicis brevis (APB), flexor pollicis brevis (FPB), opponens pollicis (OPP)). The attachment between the thenar muscles and TCL implies a relationship between the tissues. The thenar muscles rely on their origins for thumb motion and force production. However, individual thenar origin information is lacking. Further information regarding the anatomical relationship between the individual thenar muscles and TCL may provide insight into thenar muscle function. In addition, the TCL responds to thenar muscle contraction as shown by volar migration of the TCL during various thumb movements. …

A Computational Assessment Of Lisfranc Injuries And Their Surgical Repairs, Michael Perez

Theses and Dissertations

While Lisfranc injuries in the mid foot are less common than other ankle and mid foot injuries, they pose challenges in both properly identifying them and treating them. When Lisfranc injuries are ligamentous and do not include obvious fractures, they are very challenging for clinicians to identify unless weight bearing radiographs are used. The result is that 20%-40% of Lisfranc injuries are missed in the initial evaluation. Even when injuries are correctly identified the outcomes of surgical procedures remain poor. Existing literature has compared the different surgical procedures but has not had a standard approach or procedures across studies. This …

Development And Exploration Of A Z-Shaped Foot And Ankle Internal Fixation Plate, Rhaz Shaghaghi Paul, Ian Hames, Sean Rich

Williams Honors College, Honors Research Projects

This paper will detail the design process of developing a Z-shaped foot and ankle internal fixation plating system. Group 6: Plates for the Sole was made up of 5 team members, who worked together to accommodate their client’s request to complete a biomechanical analysis of a Z-Plate design and a construct a prototype. The Z-Plate’s purpose is to provide podiatrists with a new solution that can fit nicely on the small, irregular bones of the foot, while also remaining strong enough to withstand the forces and torques of the foot.

Estimation Of Multi-Directional Ankle Impedance As A Function Of Lower Extremity Muscle Activation, Lauren Knop

Dissertations, Master's Theses and Master's Reports

The purpose of this research is to investigate the relationship between the mechanical impedance of the human ankle and the corresponding lower extremity muscle activity. Three experimental studies were performed to measure the ankle impedance about multiple degrees of freedom (DOF), while the ankle was subjected to different loading conditions and different levels of muscle activity. The first study determined the non-loaded ankle impedance in the sagittal, frontal, and transverse anatomical planes while the ankle was suspended above the ground. The subjects actively co-contracted their agonist and antagonistic muscles to various levels, measured using electromyography (EMG). An Artificial Neural Network …