Artificial Intelligence and Robotics Commons^™

Alphamissense Predictions And Clinvar Annotations: A Deep Learning Approach To Uveal Melanoma, David J. Taylor Gonzalez, Mak B. Djulbegovic, Meghan Sharma, Michael Antonietti, Colin K. Kim, Vladimir N. Uversky, Carol L. Karp, Carol L. Shields, Matthew W. Wilson

Wills Eye Hospital Papers

OBJECTIVE: Uveal melanoma (UM) poses significant diagnostic and prognostic challenges due to its variable genetic landscape. We explore the use of a novel deep learning tool to assess the functional impact of genetic mutations in UM.

DESIGN: A cross-sectional bioinformatics exploratory data analysis of genetic mutations from UM cases.

SUBJECTS: Genetic data from patients diagnosed with UM were analyzed, explicitly focusing on missense mutations sourced from the Catalogue of Somatic Mutations in Cancer (COSMIC) database.

METHODS: We identified missense mutations frequently observed in UM using the COSMIC database, assessed their potential pathogenicity using AlphaMissense, and visualized mutations using AlphaFold. Clinical …

Ai Model For Predicting Asthma Prognosis In Children, Elham Sagheb, Chung-Il Wi, Katherine S King, Bhavani Singh Agnikula Kshatriya, Euijung Ryu, Hongfang Liu, Miguel A Park, Hee Yun Seol, Shauna M Overgaard, Deepak K Sharma, Young J Juhn, Sunghwan Sohn

Faculty, Staff and Student Publications

BACKGROUND: Childhood asthma often continues into adulthood, but some children experience remission. Utilizing electronic health records (EHRs) to predict asthma prognosis can aid health care providers and patients in developing effective prioritized care plans.

OBJECTIVE: We aimed to develop artificial intelligence (AI) models using various clinical variables extracted from EHRs to predict childhood asthma prognosis (remission vs no remission) in different age groups.

METHODS: We developed AI models utilizing patients' EHRs during the first 6, 9, or 12 years of their lives to predict their asthma prognosis status at ages 6 to 9, 9 to 12, or 12 to 15 …

Exploring The Biasing Effects Of Gender On Personality Disorder Diagnoses Formulated By Artificial Intelligence, Zoe Colclough

Student Theses

Gender bias is prevalent in personality disorder assessments, and while artificial intelligence has been posited as a solution to improve diagnostic objectivity and accuracy, the potential for such technologies to propagate human gender bias in mental health contexts remains underexplored. This study investigated the influences of gender bias on the diagnostic performance of ChatGPT-4o for personality disorders using three factorial research designs, which involved experimentally manipulating patient gender in a combined sample of 360 vignettes and case studies. Vignettes were synthesized through a novel artificial intelligence-assisted methodology established for this research, and case studies were identified from the literature. Significant …

Time Series Deep Learning Approach For The Intermittent Operational Performance Of A Wellhead Water Treatment And Desalination System, Michael G. Clement

Electronic Theses, Projects, and Dissertations

Distributed water treatment and desalination (DWTD) systems are becoming significant for serving disadvantaged communities that are geographically segregated from centralized water distribution networks. However, given the remote nature of the communities, these systems must operate autonomously adapting to intermittent operations due to varying water use patterns and unavailability of continuous manual labor support. Machine Learning models describing and forecasting system performance are critical, allowing for model-based control, performance forecasting, fault detection, and determination of causal relationships among process attributes. Accordingly, graph convolutional neural networks with an attention mechanism (GATConv) were developed to describe the intermittent operational profiles of a wellhead …

Learning Behaviors In Physics-Informed Deep Learning, Alex Glover

Electronic Theses and Dissertations

Physics-informed deep learning is a methodology in artificial intelligence aimed at combating the large training data requirement and the barrier of domain awareness that deep learning architectures commonly face in applications. Stochastic modeling integrated into the predictive models provides that domain knowledge. Variations of the Intelligent Driving Model impact the learning behaviors of the joint-training architecture. This thesis examines the effect of substituting the standard linear Intelligent Driving Model with a modified nonlinear version, as applied to real human driving behavior on the I-80 interstate. The experimentation also critically evaluates the complications that impede the viability of this architecture in …

Towards Reliable Ml: Data Attribution And Adversarial Robustness, Xiaosen Zheng

Dissertations and Theses Collection (Open Access)

Modern machine learning (ML) models achieve remarkable success, but face critical reliability challenges. This thesis advances two pillars of reliable ML systems: interpretability through data attribution and robustness against adversarial threats.

In the first part, we develop novel data attribution methods to elucidate the data-model relationship. We establish the critical role of memorization in model generalization through token-level influence analysis, extend sample-level attribution to diffusion models with effective approximation techniques, and introduce REGMIX, a group-level approach that predicts data mixture performance using small-scale experiments. These contributions provide practitioners with scalable tools to audit training data impacts across modalities.

The second …

Disentangling User Preferences Towards Self-Interpretable Recommender Systems, Nhu Thuat Tran

Dissertations and Theses Collection (Open Access)

Understanding user preferences remains a central challenge in recommender systems due to their inherently complex, unstructured, and multi-faceted nature, exacerbated by the sparsity of user interaction data. Traditional approaches often compress user interests into a single latent vector, overlooking the fact that user preferences are typically shaped by multiple underlying factors that differ across individuals. These latent drivers are not directly observable and must be discovered through unsupervised modeling, further complicated by limited historical interactions per user.

This dissertation addresses these challenges by introducing a principled framework for multiinterest modeling, which disentangles user behaviors into multiple latent factors to better …

Multiobjective Linear Ensembles For Robust And Sparse Training Of Few-Bit Neural Networks, Ambrogio Maria Bernardelli, Stefano Gualandi, Simone Milanesi, Hoong Chuin Lau, Neil Yorke-Smith

Research Collection School Of Computing and Information Systems

Training neural networks (NNs) using combinatorial optimization solvers has gained attention in recent years. In low-data settings, the use of state-of-the-art mixed integer linear programming solvers, for instance, has the potential to exactly train an NN while avoiding computing-intensive training and hyperparameter tuning and simultaneously training and sparsifying the network. We study the case of few-bit discrete-valued neural networks, both binarized neural networks (BNNs) whose values are restricted to ±1 and integer-valued neural networks (INNs) whose values lie in the range {−P,…,P}. Few-bit NNs receive increasing recognition because of their lightweight architecture and ability to run on low-power devices: for …

Reverse Modeling In Large Language Models, Sicheng Yu, Yuanchen Xu, Cunxiao Du, Yanying Zhou, Minghui Qiu, Qianru Sun, Hao Zhang, Jiawei Wu

Research Collection School Of Computing and Information Systems

Humans are accustomed to reading and writing in a forward manner, and this natural bias extends to text understanding in auto-regressive large language models (LLMs). This paper investigates whether LLMs, like humans, struggle with reverse modeling, specifically with reversed text inputs. We found that publicly available pre-trained LLMs cannot understand such inputs. However, LLMs trained from scratch with both forward and reverse texts can understand them equally well during inference. Our case study shows that different-content texts result in different losses if input (to LLMs) in different directions---some get lower losses for forward while some for reverse. This leads us …

Creating Talking Points For Client Advisers At Banks To Promote Sustainable Investing, Wewe Zi Yi, Pradeep Varakantham, Alan Megargel

Research Collection School Of Computing and Information Systems

Environmental, social and governance (ESG) factors have become key nonfinancial factors for investors to evaluate companies with respect to understanding material risks and growth opportunities. While not mandatory, companies are providing ESG reports that outline progress in different ESG metrics (six broad metrics and 15 specific ones). Client advisers (CAs) read these reports to identify key metrics of interest to investors. Given the number of companies and investment products, however, it is not feasible for CAs to read all the reports, which can sometimes run into tens or hundreds of pages). The authors have developed multiple frameworks building on leading …

Hello Again! Llm-Powered Personalized Agent For Long-Term Dialogue, Hao Li, Chenghao Yang, An Zhang, Yang Deng, Xiang Wang, Tat-Seng Chua

Research Collection School Of Computing and Information Systems

Open-domain dialogue systems have seen remarkable advancements with the development of large language models (LLMs). Nonetheless, most existing dialogue systems predominantly focus on brief single-session interactions, neglecting the real-world demands for long-term companionship and personalized interactions with chatbots. Crucial to addressing this real-world need are event summary and persona management, which enable reasoning for appropriate long-term dialogue responses. Recent progress in the human-like cognitive and reasoning capabilities of LLMs suggests that LLM-based agents could significantly enhance automated perception, decision-making, and problem-solving. In response to this potential, we introduce a model-agnostic framework, the Long-term Dialogue Agent (LD-Agent), which incorporates three independently …

Query Understanding In Llm-Based Conversational Information Seeking, Yifei Yuan, Zahra Abbasiantaeb, Yang Deng, Mohammad Aliannejadi

Research Collection School Of Computing and Information Systems

Query understanding in Conversational Information Seeking (CIS) involves accurately interpreting user intent through context-aware interactions. This includes resolving ambiguities, refining queries, and adapting to evolving information needs. Large Language Models (LLMs) enhance this process by interpreting nuanced language and adapting dynamically, improving the relevance and precision of search results in real-time. In this tutorial, we explore advanced techniques to enhance query understanding in LLM-based CIS systems. We delve into LLM-driven methods for developing robust evaluation metrics to assess query understanding quality in multiturn interactions, strategies for building more interactive systems, and applications like proactive query management and query reformulation. We …

Sans: Efficient Densest Subgraph Discovery Over Relational Graphs Without Materialization, Yudong Niu, Yuchen Li, Jiaxin Jiang, Laks V. S. Lakshmanan

Research Collection School Of Computing and Information Systems

How can we efficiently identify the densest subgraph over relational graphs? Existing dense subgraph discovery (DSD) approaches assume that a relational graph H is already derived from a heterogeneous data source and they focus on efficient discovery of the densest subgraph on the materialized H. Unfortunately, materializing relational graphs can be resource-intensive, which thus limits the practical usefulness of existing algorithms over large datasets. To mitigate this, we propose a novel Summary-bAsed deNsest Subgraph discovery (SANS) system. Our unique summary-based peeling algorithm forms the core of SANS. Following the peeling paradigm, it utilizes summaries of each node's neighborhood to efficiently …

Gamba: Marry Gaussian Splatting With Mamba For Single-View 3d Reconstruction, Qiuhong Shen, Zike Wu, Xuanyu Yi, Pan Zhou, Hanwang Zhang, Shuicheng Yan, Xinchao Wang

Research Collection School Of Computing and Information Systems

We tackle the challenge of efficiently reconstructing a 3D asset from a single image at millisecond speed. Existing methods for single-image 3D reconstruction are primarily based on Score Distillation Sampling (SDS) with Neural 3D representations. Despite promising results, these approaches encounter practical limitations due to lengthy optimizations and significant memory consumption. In this work, we introduce Gamba, an end-to-end 3D reconstruction model from a single-view image, emphasizing two main insights: (1) Efficient Backbone Design: introducing a Mamba-based GambaFormer network to model 3D Gaussian Splatting (3DGS) reconstruction as sequential prediction with linear scalability of token length, thereby accommodating a substantial number …

Hierarchical Learning-Based Graph Partition For Large-Scale Vehicle Routing Problems, Yuxin Pan, Ruohong Liu, Yize Chen, Zhiguang Cao, Fangzhen Lin

Research Collection School Of Computing and Information Systems

Neural solvers based on the divide-and-conquer approach for Vehicle Routing Problems (VRPs) in general, and capacitated VRP (CVRP) in particular, integrates the global partition of an instance with local constructions for each subproblem to enhance generalization. However, during the global partition phase, misclusterings within subgraphs have a tendency to progressively compound throughout the multi-step decoding process of the learning-based partition policy. This suboptimal behavior in the global partition phase, in turn, may lead to a dramatic deterioration in the performance of the overall decomposition-based system, despite using optimal local constructions. To address these challenges, we propose a versatile Hierarchical Learning-based …

Enhancing Sub-Optimal Trajectory Stitching: Spatial Composition Rvs For Offline Rl, Sheng Zang, Zhiguang Cao, Bo An, Senthilnath Jayavelu, Xiaoli Li

Research Collection School Of Computing and Information Systems

Reinforcement learning via supervised learning (RvS) has been known as a burgeoning paradigm for offline reinforcement learning (RL). While return-conditioned RvS (RvS-R) predominates across a wide range of datasets pertaining to the offline RL tasks, recent findings suggest that goal-conditioned RvS (RvS-G) outperforms in specific sub-optimal datasets where trajectory stitching is crucial for achieving optimal performance. However, the underlying reasons for this superiority remain insufficiently explored. In this paper, employing didactic experiments and theoretical analysis, we reveal that the proficiency of RvS-G in stitching trajectories arises from its adeptness in generalizing to unknown goals during evaluation. Building on this insight, …

On Learning Informative Trajectory Embeddings For Imitation, Classification And Regression, Zichang Ge, Changyu Chen, Arunesh Sinha, Pradeep Varakantham

Research Collection School Of Computing and Information Systems

In real-world sequential decision making tasks like autonomousdriving, robotics, and healthcare, learning from observed state-action trajectories is critical for tasks like imitation, classification,and clustering. For example, self-driving cars must replicate humandriving behaviors, while robots and healthcare systems benefitfrom modeling decision sequences, whether or not they come fromexpert data. Existing trajectory encoding methods often focus onspecific tasks or rely on reward signals, limiting their ability togeneralize across domains and tasks.Inspired by the success of embedding models like CLIP andBERT in static domains, we propose a novel method for embeddingstate-action trajectories into a latent space that captures the skillsand competencies in the …

“Ronaldo’S A Poser!”: How The Use Of Generative Ai Shapes Debates In Online Forums, Yuhan Zeng, Yingxuan Shi, Xuehan Huang, Fiona Fui-Hoon Nah, Ray Lc

Research Collection School Of Computing and Information Systems

Online debates can enhance critical thinking but may escalate into hostile attacks. As humans are increasingly reliant on Generative AI (GenAI) in writing tasks, we need to understand how people utilize GenAI in online debates. To examine the patterns of writing behavior while making arguments with GenAI, we created an online forum for soccer fans to engage in turn-based and free debates in a post format with the assistance of ChatGPT, arguing on the topic of "Messi vs Ronaldo". After 13 sessions of two-part study and semi-structured interviews with 39 participants, we conducted content and thematic analyses to integrate insights …

Iot In Sustainability And Iot In The Ai And Metaverse Age, Yuzhou Qian, Keng Siau

Research Collection School Of Computing and Information Systems

The Internet of Things (IoT) is a modern technology that has gained large popularity and is still developing. Connecting heterogeneous devices, such as phones, vehicles, and household appliances, IoT has brought convenience to our lives. Further, IoT plays a significant role in enhancing environmental sustainability. It provides timely data about different devices and enables users and managers to directly control the objects. IoT can optimize the existing energy systems and promote the usage of renewable technologies. In this paper, we discuss how IoT supports green initiatives (i.e., how it is applied in different sectors), how it can be "green" itself …

Cyberoception: Finding A Painlessly-Measurable New Sense In The Cyberworld Towards Emotion-Awareness In Computing, Tadashi Okoshi, Zexiong Gao, Yi Zhen Tan, Takumi Karasawa, Takeshi Miki, Wataru Sasaki, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

In Affective computing, recognizing users’ emotions accurately is the basis of affective human–computer interaction. Understanding users’ interoception contributes to a better understanding of individually different emotional abilities, which is essential for achieving inter-individually accurate emotion estimation. However, existing interoception measurement methods, such as the heart rate discrimination task, have several limitations, including their dependence on a well-controlled laboratory environment and precision apparatus, making monitoring users’ interoception challenging. This study aims to determine other forms of data that can explain users’ interoceptive or similar states in their real-world lives and propose a novel hypothetical concept “cyberoception,” a new sense (1) which …