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Towards Personalized Medicine Using Systems Biology And Machine Learning, Calin Voichita 2013 Wayne State University

Towards Personalized Medicine Using Systems Biology And Machine Learning, Calin Voichita

Wayne State University Dissertations

The rate of acquiring biological data has greatly surpassed our ability to interpret it. At the same time, we have started to understand that evolution of many diseases such as cancer, are the results of the interplay between the disease itself and the immune system of the host. It is now well accepted that cancer is not a single disease, but a “complex collection of distinct genetic diseases united by common hallmarks”. Understanding the differences between such disease subtypes is key not only in providing adequate treatments for known subtypes but also identifying new ones. These unforeseen disease subtypes are …


Real-Time Control Of A Robot Arm Using An Inexpensive System For Electroencephalography Aided By Artificial Intelligence, James O'Connor 2013 Connecticut College

Real-Time Control Of A Robot Arm Using An Inexpensive System For Electroencephalography Aided By Artificial Intelligence, James O'Connor

Computer Science Honors Papers

No abstract provided.


Reducing Communication Delay Variability For A Group Of Robots, Goncalo Martins 2013 University of Denver

Reducing Communication Delay Variability For A Group Of Robots, Goncalo Martins

Electronic Theses and Dissertations

A novel architecture is presented for reducing communication delay variability for a group of robots. This architecture relies on using three components: a microprocessor architecture that allows deterministic real-time tasks; an event-based communication protocol in which nodes transmit in a TDMA fashion, without the need of global clock synchronization techniques; and a novel communication scheme that enables deterministic communications by allowing senders to transmit without regard for the state of the medium or coordination with other senders, and receivers can tease apart messages sent simultaneously with a high probability of success. This approach compared to others, allows simultaneous communications without …


Nonlinear Granger Causality And Its Application In Decoding Of Human Reaching Intentions, Mengting Liu 2013 Louisiana Tech University

Nonlinear Granger Causality And Its Application In Decoding Of Human Reaching Intentions, Mengting Liu

Doctoral Dissertations

Multi-electrode recording is a key technology that allows the brain mechanisms of decision making, cognition, and their breakdown in diseases to be studied from a network perspective. As the hypotheses concerning the role of neural interactions in cognitive paradigms become increasingly more elaborate, the ability to evaluate the direction of neural interactions in neural networks holds the key to distinguishing their functional significance.

Granger Causality (GC) is used to detect the directional influence of signals between multiple locations. To extract the nonlinear directional flow, GC was completed through a nonlinear predictive approach using radial basis functions (RBF). Furthermore, to obtain …


Interpreting Individual Classifications Of Hierarchical Networks, Will Landecker, Michael David Thomure, Luis M.A. Bettencourt, Melanie Mitchell, Garrett T. Kenyon, Steven P. Brumby 2013 Portland State University

Interpreting Individual Classifications Of Hierarchical Networks, Will Landecker, Michael David Thomure, Luis M.A. Bettencourt, Melanie Mitchell, Garrett T. Kenyon, Steven P. Brumby

Computer Science Faculty Publications and Presentations

Hierarchical networks are known to achieve high classification accuracy on difficult machine-learning tasks. For many applications, a clear explanation of why the data was classified a certain way is just as important as the classification itself. However, the complexity of hierarchical networks makes them ill-suited for existing explanation methods. We propose a new method, contribution propagation, that gives per-instance explanations of a trained network's classifications. We give theoretical foundations for the proposed method, and evaluate its correctness empirically. Finally, we use the resulting explanations to reveal unexpected behavior of networks that achieve high accuracy on visual object-recognition tasks using well-known …


Using Mapreduce Streaming For Distributed Life Simulation On The Cloud, Atanas Radenski 2013 Chapman University

Using Mapreduce Streaming For Distributed Life Simulation On The Cloud, Atanas Radenski

Mathematics, Physics, and Computer Science Faculty Books and Book Chapters

Distributed software simulations are indispensable in the study of large-scale life models but often require the use of technically complex lower-level distributed computing frameworks, such as MPI. We propose to overcome the complexity challenge by applying the emerging MapReduce (MR) model to distributed life simulations and by running such simulations on the cloud. Technically, we design optimized MR streaming algorithms for discrete and continuous versions of Conway’s life according to a general MR streaming pattern. We chose life because it is simple enough as a testbed for MR’s applicability to a-life simulations and general enough to make our results applicable …


Decision Support For Assorted Populations In Uncertain And Congested Environments, Pradeep Reddy VARAKANTHAM, Asrar Ahmed, Shih-Fen CHENG 2013 Singapore Management University

Decision Support For Assorted Populations In Uncertain And Congested Environments, Pradeep Reddy Varakantham, Asrar Ahmed, Shih-Fen Cheng

Research Collection School Of Computing and Information Systems

This research is motivated by large scale problems in urban transportation and labor mobility where there is congestion for resources and uncertainty in movement. In such domains, even though the individual agents do not have an identity of their own and do not explicitly interact with other agents, they effect other agents. While there has been much research in handling such implicit effects, it has primarily assumed deterministic movements of agents. We address the issue of decision support for individual agents that are identical and have involuntary movements in dynamic environments. For instance, in a taxi fleet serving a city, …


Uncertain Congestion Games With Assorted Human Agent Populations , Pradeep Reddy VARAKANTHAM, Asrar Ahmed, Shih-Fen CHENG 2013 Singapore Management University

Uncertain Congestion Games With Assorted Human Agent Populations , Pradeep Reddy Varakantham, Asrar Ahmed, Shih-Fen Cheng

Research Collection School Of Computing and Information Systems

Congestion games model a wide variety of real-world resource congestion problems, such as selfish network routing, traffic route guidance in congested areas, taxi fleet optimization and crowd movement in busy areas. However, existing research in congestion games assumes: (a) deterministic movement of agents between resources; and (b) perfect rationality (i.e. maximizing their own expected value) of all agents. Such assumptions are not reasonable in dynamic domains where decision support has to be provided to humans. For instance, in optimizing the performance of a taxi fleet serving a city, movement of taxis can be involuntary or nondeterministic (decided by the specific …


Regret Based Robust Solutions For Uncertain Markov Decision Processes, Asrar AHMED, Pradeep Reddy VARAKANTHAM, Yossiri Adulyasak, Patrick Jaillet 2013 Singapore Management University

Regret Based Robust Solutions For Uncertain Markov Decision Processes, Asrar Ahmed, Pradeep Reddy Varakantham, Yossiri Adulyasak, Patrick Jaillet

Research Collection School Of Computing and Information Systems

In this paper, we seek robust policies for uncertain Markov Decision Processes (MDPs). Most robust optimization approaches for these problems have focussed on the computation of maximin policies which maximize the value corresponding to the worst realization of the uncertainty. Recent work has proposed minimax regret as a suitable alternative to the maximin objective for robust optimization. However, existing algorithms for handling minimax regret are restricted to models with uncertainty over rewards only. We provide algorithms that employ sampling to improve across multiple dimensions: (a) Handle uncertainties over both transition and reward models; (b) Dependence of model uncertainties across state, …


Introduction To Neutrosophic Measure, Neutrosophic Integral, And Neutrosophic Probability, Florentin Smarandache 2013 University of New Mexico

Introduction To Neutrosophic Measure, Neutrosophic Integral, And Neutrosophic Probability, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this book, we introduce for the first time the notions of neutrosophic measure and neutrosophic integral, and we develop the 1995 notion of neutrosophic probability. We present many practical examples.

It is possible to define the neutrosophic measure and consequently the neutrosophic integral and neutrosophic probability in many ways, because there are various types of indeterminacies, depending on the problem we need to solve. Neutrosophics study the indeterminacy. Indeterminacy is different from randomness. It can be caused by physical space materials and type of construction, by items involved in the space, etc.


Drift Detection Using Uncertainty Distribution Divergence, Patrick Lindstrom, Brian Mac Namee, Sarah Jane Delany 2013 Technological University Dublin

Drift Detection Using Uncertainty Distribution Divergence, Patrick Lindstrom, Brian Mac Namee, Sarah Jane Delany

Articles

Data generated from naturally occurring processes tends to be non-stationary. For example, seasonal and gradual changes in climate data and sudden changes in financial data. In machine learning the degradation in classifier performance due to such changes in the data is known as concept drift and there are many approaches to detecting and handling it.

Most approaches to detecting concept drift, however, make the assumption that true classes for test examples will be available at no cost shortly after classification and base the detection of concept drift on measures relying on these labels. The high labelling cost in many domains …


Robotic Swarming Without Inter-Agent Communication, Daniel Jonathan Standish 2013 University of South Florida

Robotic Swarming Without Inter-Agent Communication, Daniel Jonathan Standish

USF Tampa Graduate Theses and Dissertations

Many physical and algorithmic swarms utilize inter-agent communication to achieve advanced swarming behaviors. These swarms are inspired by biological swarms that can be seen throughout nature and include bee swarms, ant colonies, fish schools, and bird flocks. These biological swarms do not utilize inter-agent communication like their physical and algorithmic counterparts. Instead, organisms in nature rely on a local awareness of other swarm members that facilitates proper swarm motion and behavior. This research aims to pursue an effective swarm algorithm using only line-of-sight proximity information and no inter-agent communication. It is expected that the swarm performance will be lower than …


Analyzing Environmental Change And Prehistoric Hunter Behavior Through A 3d Time-Lapsed Model With Level Auto-Generation And Cultural Algorithms, Samuel Dustin Stanley 2013 Wayne State University

Analyzing Environmental Change And Prehistoric Hunter Behavior Through A 3d Time-Lapsed Model With Level Auto-Generation And Cultural Algorithms, Samuel Dustin Stanley

Wayne State University Theses

This paper describes a system containing two portions whose purpose it is to help further the Alpena-Amberley Land Bridge research project and similar archaeological research. The first portion is a "time engine" which one can utilize to navigate through time in order to see how environmental conditions evolved as time passed, or to run experiments during a desired time period. The second portion is a hunting blind cultural algorithm, which is built on top of the time engine as well as Palazzolo's program. In this portion, the AI hunting blinds react to the goals that they are trying to achieve, …


Visual Semantic Segmentation And Its Applications, Jizhou Gao 2013 University of Kentucky

Visual Semantic Segmentation And Its Applications, Jizhou Gao

Theses and Dissertations--Computer Science

This dissertation addresses the difficulties of semantic segmentation when dealing with an extensive collection of images and 3D point clouds. Due to the ubiquity of digital cameras that help capture the world around us, as well as the advanced scanning techniques that are able to record 3D replicas of real cities, the sheer amount of visual data available presents many opportunities for both academic research and industrial applications. But the mere quantity of data also poses a tremendous challenge. In particular, the problem of distilling useful information from such a large repository of visual data has attracted ongoing interests in …


Coupling Numerical Simulation And Pattern Recognition To Model Production And Evaluate Carbon Dioxide Injection In Shale Gas Reservoir, Amirmasoud Kalantari-Dahaghi 2013 West Virginia University

Coupling Numerical Simulation And Pattern Recognition To Model Production And Evaluate Carbon Dioxide Injection In Shale Gas Reservoir, Amirmasoud Kalantari-Dahaghi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Massive multi-cluster, multi-stage hydraulic fractures have significantly increased the complexity of the flow behavior in shale. This has translated into multiple challenges in the modeling of production from shale wells.

Most commonly used numerical techniques for modeling production from shale wells are Explicit Hydraulic Fracture (EHF) and Stimulated Reservoir Volume (SRV). Model setup for the EHF technique is long and laborious and its implementation is computationally expensive, such that it becomes impractical to model beyond a single pad. On the other hand, identifying the extent and conductivity of SRV is a challenging proposition. SRV technique is commonly used to simplify …


Moving Object Detection With Laser Scanners, Christoph MERTZ, Luis E. NAVARRO-SERMENT, Robert MACLACHLAN, Paul RYBSKI, Aaron STEINFELD, Arne SUPPE, Christopher URMSON, Nicolas VANDAPEL, Martial HEBERT, Chuck THORPE, David DUGGINS, Jay GOWDY 2013 Singapore Management University

Moving Object Detection With Laser Scanners, Christoph Mertz, Luis E. Navarro-Serment, Robert Maclachlan, Paul Rybski, Aaron Steinfeld, Arne Suppe, Christopher Urmson, Nicolas Vandapel, Martial Hebert, Chuck Thorpe, David Duggins, Jay Gowdy

Research Collection School Of Computing and Information Systems

The detection and tracking of moving objects is an essential task in robotics. The CMU-RI Navlab group has developed such a system that uses a laser scanner as its primary sensor. We will describe our algorithm and its use in several applications. Our system worked successfully on indoor and outdoor platforms and with several different kinds and configurations of two-dimensional and three-dimensional laser scanners. The applications vary from collision warning systems, people classification, observing human tracks, and input to a dynamic planner. Several of these systems were evaluated in live field tests and shown to be robust and reliable. (C) …


Automated Parameter Tuning Framework For Heterogeneous And Large Instances: Case Study In Quadratic Assignment Problem, Linda LINDAWATI, Zhi Yuan, Hoong Chuin LAU, Feida ZHU 2013 Singapore Management University

Automated Parameter Tuning Framework For Heterogeneous And Large Instances: Case Study In Quadratic Assignment Problem, Linda Lindawati, Zhi Yuan, Hoong Chuin Lau, Feida Zhu

Research Collection School Of Computing and Information Systems

This paper is concerned with automated tuning of parameters of algorithms to handle heterogeneous and large instances. We propose an automated parameter tuning framework with the capability to provide instance-specific parameter configurations. We report preliminary results on the Quadratic Assignment Problem (QAP) and show that our framework provides a significant improvement on solutions qualities with much smaller tuning computational time.


Clustering Of Search Trajectory And Its Application To Parameter Tuning, Linda Lindawati, Hoong Chuin LAU, David LO 2013 Singapore Management University

Clustering Of Search Trajectory And Its Application To Parameter Tuning, Linda Lindawati, Hoong Chuin Lau, David Lo

Research Collection School Of Computing and Information Systems

This paper is concerned with automated classification of Combinatorial Optimization Problem instances for instance-specific parameter tuning purpose. We propose the CluPaTra Framework, a generic approach to CLUster instances based on similar PAtterns according to search TRAjectories and apply it on parameter tuning. The key idea is to use the search trajectory as a generic feature for clustering problem instances. The advantage of using search trajectory is that it can be obtained from any local-search based algorithm with small additional computation time. We explore and compare two different search trajectory representations, two sequence alignment techniques (to calculate similarities) as well as …


Sensor Feature Selection And Combination For Stress Identification Using Combinatorial Fusion, Yong DENG, Zhonghai WU, Chao-Hsien CHU, Qixun ZHANG, D. Frank HSU 2013 Peking University

Sensor Feature Selection And Combination For Stress Identification Using Combinatorial Fusion, Yong Deng, Zhonghai Wu, Chao-Hsien Chu, Qixun Zhang, D. Frank Hsu

Research Collection School Of Computing and Information Systems

The identification of stressfulness under certain driving condition is an important issue for safety, security and health. Sensors and systems have been placed or implemented as wearable devices for drivers. Features are extracted from the data collected and combined to predict symptoms. The challenge is to select the feature set most relevant for stress. In this paper, we propose a feature selection method based on the performance and the diversity between two features. The feature sets selected are then combined using a combinatorial fusion. We also compare our results with other combination methods such as naïve Bayes, support vector machine, …


Security Games With Interval Uncertainty, Md Towhidul Islam 2013 University of Texas at El Paso

Security Games With Interval Uncertainty, Md Towhidul Islam

Open Access Theses & Dissertations

Game theory has become an important tool in solving real-life decision making problems. Security games use the concept of game theory in adversarial scenarios to protect critical infrastructure. The main purpose of security games is to allocate security resources among various targets and maximize payoff for the defender considering various kinds of attackers. It is hard for domain experts to predict the attacker's behavior, so one of the major challenges in describing this game model is representing uncertainty about the attacker's payoff. Several approaches have been developed to generate these game models based on uncertainty, such as Bayesian games. However …


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