Multichannel Modulation Of Depolarizing And Repolarizing Ion Currents Increases The Positive Rate-Dependent Action Potential Prolongation,
2023
CUNY New York City College of Technology
Multichannel Modulation Of Depolarizing And Repolarizing Ion Currents Increases The Positive Rate-Dependent Action Potential Prolongation, Candido Cabo
Publications and Research
Prolongation of the action potential duration (APD) could prevent reentrant arrhythmias if prolongation occurs at the fast excitation rates of tachycardia with minimal prolongation at slow excitation rates (i.e., if prolongation is positive rate-dependent). APD prolongation by current anti-arrhythmic agents is either reverse (larger APD prolongation at slow rates than at fast rates) or neutral (similar APD prolongation at slow and fast rates), which may not result in an effective anti-arrhythmic action. In this report we show that, in computer models of the human ventricular action potential, the combined modulation of both depolarizing and repolarizing ion currents results in a …
Heart Rate Response And Locomotor Activity Of Female Skateboarders, Bipoc Skateboarders, And Non-Skateboard Users During A Typical Session At A Community Skatepark,
2023
California State University San Marcos
Heart Rate Response And Locomotor Activity Of Female Skateboarders, Bipoc Skateboarders, And Non-Skateboard Users During A Typical Session At A Community Skatepark, Jeff A. Nessler, Alivia L. Lundquist, Natalie Casas Jimenez, Sean C. Newcomer
International Journal of Exercise Science
International Journal of Exercise Science 16(7): 599-612, 2023. Prior research has demonstrated that male adults and youth engaged in skateboarding at community skateparks achieve heart rates that meet or exceed recommendations for exercise by the CDC. However, these studies do not adequately evaluate other non-traditional or ethnically diverse users who may differ in how they utilize the skatepark and in their cardiovascular response. The purpose of this experiment was to measure heart rate response and locomotor movement in three lesser studied groups that frequently utilize community skateparks, and to compare these results with those reported previously in male adult and …
Effect Of High Intensity Interval Training Under Mask On Force Vital Capacity In Football Players,
2023
Khon Kean University
Effect Of High Intensity Interval Training Under Mask On Force Vital Capacity In Football Players, Neranoch Bumrung, Apiwan Manimmanakorn, Natthapon Traiperm
International Journal of Exercise Science
International Journal of Exercise Science 16(6): 576-586, 2023. The purpose of the study was to investigate the effect of high interval training (HIIT) under mask on forced vital capacity in football players. Fourteen male football players (age 20 ± 2 years) were randomized into the without mask group (CON) or with the 2 difference mask groups [Surgical mask (SM), FFP2 mask (FM)]. HIIT program were implemented six movements in each session three times per week. Body composition, forced vital capacity and percutaneous oxygen saturation test were taken before and after 4 weeks intervention. The results show that forced vital capacity …
Muscle Thickness, Echo-Intensity, Peak Force, Time Under Tension, Total Load Lifted, And Perception Of Effort Comparisons Between Two Abdominal Crunch Resistance Training Protocols In Recreationally-Trained Participants,
2023
California State University, Northridge
Muscle Thickness, Echo-Intensity, Peak Force, Time Under Tension, Total Load Lifted, And Perception Of Effort Comparisons Between Two Abdominal Crunch Resistance Training Protocols In Recreationally-Trained Participants, Keanna Sullivan, Paula R. Ferreira, Vincent G.F. Martinez, Paulo Henrique Marchetti
International Journal of Exercise Science
International Journal of Exercise Science 16(6): 538-549, 2023. The primary purpose of this study was to evaluate acute dose response of different intensities with total volume equalized during the abdominal crunch exercise on muscle thickness, echo-intensity, peak force, time under tension, total load lifted, and perception of effort in recreationally-trained participants. Fifteen resistance-trained participants (23 ± 3 years) performed the abdominal crunch exercise in one of two different resistance training (RT) protocols in a randomized order: RT4x10RM (4 sets of 10RM / 1-min rest) or RT1x40RM (1 set of 40RM). Muscle thickness (MT), echo- intensity (EI), peak force …
Comparison Of A Ramp Cycle Ergometer And A Staged Assault Fitness Assaultbike Protocol For The Assessment Of Vo2max,
2023
University of Georgia
Comparison Of A Ramp Cycle Ergometer And A Staged Assault Fitness Assaultbike Protocol For The Assessment Of Vo2max, Regis C. Pearson, Sara A. Garcia, Nathan T. Jenkins
International Journal of Exercise Science
International Journal of Exercise Science 16(4): 613-619, 2023. We propose a new VO2max test using a progressive staged protocol on an Assault Fitness AssaultBike. Twelve healthy males performed a traditional ramp cycle ergometer test (TRAD) and a progressively staged AssaultBike protocol (AB) in a counterbalanced order. AB elicited higher immediate post-exercise lactate, absolute and relative VO2max, and maximum heart rate than TRAD (P = 0.006, P = 0.014, P = 0.007, and P = 0.001, respectively). The protocol outlined herein may provide a more accurate assessment of VO2max due to greater skeletal muscle mass recruitment that is more representative …
The Relationship Between Muscular Strength, Jump Power, And Bone Health In Collegiate Distance Runners,
2023
Loyola Marymount University
The Relationship Between Muscular Strength, Jump Power, And Bone Health In Collegiate Distance Runners, Daisy E. Huerta, Jarred M. Norris, William P. Mccormack, Todd C. Shoepe, Hawley C. Almstedt
International Journal of Exercise Science
International Journal of Exercise Science 16(4): 563-575, 2023. Participation in sports, especially those involving impact loading, enhance bone mineral content (BMC) and density (BMD). Additionally, participation in impact loading sports may strengthen relationships between strength or power and bone variables. The purpose of this investigation was to examine relationships between measures of muscular performance and bone variables in Division I endurance athletes (29 males, 31 females, 19.6 ± 1.4 years). Dual-energy x-ray absorptiometry (DXA) scans were analyzed at the anterior-posterior (AP) and lateral (LAT) spine, femoral neck (FN), total hip (TH), whole body (WB), and ultra-distal forearm (UD) for BMC …
Can 5-Weeks Of Hypopressive Exercise Influence Sagittal Lumbo-Pelvic Position In Athletic And Non-Athletic Females?,
2023
University Methodist Center IPA
Can 5-Weeks Of Hypopressive Exercise Influence Sagittal Lumbo-Pelvic Position In Athletic And Non-Athletic Females?, Kimberly Assumpção Wojcik, Lucas Teixeira Pinheiro Machado, Carla Itatiana Bastos De Brito1, Tamara Rial Rebullido
International Journal of Exercise Science
International Journal of Exercise Science 16(4): 550-562, 2023. Hypopressive exercises (HE) are part of the Low Pressure Fitness training program which is widely used by physical therapists in the rehabilitation of the pelvic floor, abdominal and spinal musculature. The aim of this study was to compare the effects of HE on the sagittal lumbo-pelvic posture in athletic and non-athletic females. It was hypothesized that a 5-week training program of HE could influence lumbo-pelvic position while reducing abdominal circumference and low back pain in athletic and non-athletic females. Twenty normoweight females (mean age = 24.8 (SD 3.5) years; body mass index …
Older Adult Aerobic Capacity, Muscular Strength, Fitness And Body Composition After 20+ Years Of Exercise Training: A Systematic Review And Meta-Analysis,
2023
University of California, San Diego
Older Adult Aerobic Capacity, Muscular Strength, Fitness And Body Composition After 20+ Years Of Exercise Training: A Systematic Review And Meta-Analysis, Eric Leslie, Vincent Luna, Ann L. Gibson
International Journal of Exercise Science
International Journal of Exercise Science 16(3): 620-637, 2023. Older adults (³ 65 years) are recommended to participate in regular exercise to maintain health in late adulthood. The impact of long-term (20+ years) exercise training that align with the American College of Sports Medicine’s (ACSM) recommended guidelines has not been evaluated for older adults. To address this, a systematic review and meta-analyses were performed regarding the effects of long-term exercise training on older adult aerobic capacity, muscular fitness, and body composition that meet the ACSM’s recommendation for weekly training volume. Ten studies with individuals that performed cardiorespiratory or resistance exercise met …
Immediate Effect Of Gluteus Medius Kinesio-Taping On Plantar Pressure Distribution And Balance Among Healthy Individuals,
2023
Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, India
Immediate Effect Of Gluteus Medius Kinesio-Taping On Plantar Pressure Distribution And Balance Among Healthy Individuals, Deepa Shekar, Hemant K. Kalyan, Prem Venkatesan, Nithin Prakash, Karvannan Harikesavan
International Journal of Exercise Science
International Journal of Exercise Science 16(1): 587-598, 2023. Gluteus medius eccentrically regulates hip adduction and internal rotation in unilateral postures against gravity. Any weakness to Gluteus medius can lead to poor posture, impaired balance and altered plantar pressure. There is a scarcity of literature to find the immediate effect of gluteus medius kinesio-taping on plantar pressure distribution and balance among healthy individuals. A Randomized cross-over trial was conducted in outpatient physiotherapy department of Manipal Hospitals Bangalore, on 28 healthy individuals from March 2021 to April 2022. The taping was done on the dominant leg of the subjects, with no tape, …
Low-Load X High-Load Resistance Exercise: Greater Cell Swelling After A Training Session,
2023
University of Campinas, Campinas, Brazil
Low-Load X High-Load Resistance Exercise: Greater Cell Swelling After A Training Session, Gabriel Agentilho, Erick Lucena, Luis Felipe M. Teixeira, Vanessa Boas, Isadora Ribeiro, Renato Barroso, Brad Schoenfeld, Marco Uchida
International Journal of Exercise Science
International Journal of Exercise Science 16(3): 513-524, 2023. Cell swelling caused by resistance training is proposed to provide an anabolic stimulus for muscle growth and it is believed that these effects are heightened with the use of low loads. The purpose of this study was to compare the acute effects of two volume-equated resistance training (RT) protocols, low-load (LL) versus high-load (HL), on elbow flexor muscles thickness, arm circumference, and blood lactate concentration in well-trained individuals. Eight resistance-trained males performed the following two RT protocols involving unilateral elbow flexion of the dominant arm: i) LL, four sets with 50% 1 …
Entropy Of Heart Rate On Self-Selected Interval Exercises In Older Women,
2023
Physical Education Department, Federal University of Pernambuco, Recife, PE, Brazil; Grad Program in Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, PE, Brazil
Entropy Of Heart Rate On Self-Selected Interval Exercises In Older Women, Lucas E. R. Santos, Karla K. Dames, Edilaine S. D. De Oiliveira, Matheus S. S. Fernades, Tayrine O. Filgueira, Bruna M. S. Mesquita, Catarina F. C. X. M. De Souza, Eduardo Lattari, Tony M. Santos
International Journal of Exercise Science
International Journal of Exercise Science 16(2): 525-537, 2023. Non-linear analyzes such as Approximated Entropy (ApEn) and Sample Entropy (SampEn) could show the adaptability of the autonomic nervous system in relation to the dynamic changes caused by exercise. The aims of the study were: a) Investigate the effects of different Self-Selected based Interval Exercises (SSIE) configurations on Heart Rate (HR) entropy; b) Determine whether the stimuli time promote different entropy responses; c) Observe whether exercises with passive self-selected recovery time (SSRT) promote different HR entropy responses compared to those with imposed time and active recovery; and d) Determine whether post-training entropy …
Does Vdac2 Have A Bh3 Domain?,
2023
University of Mississippi
Does Vdac2 Have A Bh3 Domain?, Lillian Ferkany
Honors Theses
Mitochondrial outer membrane permeabilization (MOMP) by Bax oligomerization triggers apoptosis. BCl-2 family proteins, classified as BH3 only proteins, pro-survival proteins, or pro-apoptotic proteins, control apoptosis partly through their agonist or antagonistic effects on Bax, which are mediated by their conserved BH3 domains. All BH3 domains form an alpha helix containing 5-7 conserved hydrophobic residues, designated H0-H5, and one conserved aspartic acid that drive interaction with Bax and other ‘multi-domain’ BCl-2 members. BH3 agonists induce Bax oligomerization, while BH3 antagonists sequester Bax to prevent MOMP. We discovered that voltage dependent anion channels (VDACs) in the MOM contain a putative BH3-like domain …
Pno-Monia,
2023
Illinois Mathematics and Science Academy
Pno-Monia, Ayati Lala, Nandana Varma
Human Diseases Graphic Novels
No abstract provided.
Small Cell Lung Cancer,
2023
Illinois Mathematics and Science Academy
Small Cell Lung Cancer, Ramzi Daki '23, Breena Bulthuis, Zander Davidson, Dammy Tabiti, Addie Kobayashi
Human Diseases Graphic Novels
No abstract provided.
Fatty Liver Disease,
2023
Illinois Mathematics and Science Academy
Fatty Liver Disease, Ramzi Daki '23, Breena Bulthuis, Zander Davidson, Dammy Tabiti, Adelyn Kobayashi
Human Diseases Graphic Novels
No abstract provided.
Review Of Biomedical Applications Of Cardiovascular Tissue Engineering,
2023
Murray State University
Review Of Biomedical Applications Of Cardiovascular Tissue Engineering, Natalie M. Howard
Honors College Theses
Tissue engineering can be defined as processes that aim to generate three-dimensional functional tissues in vitrothat have been favorably altered according to the structural, biochemical, electrophysiological, and biomechanical properties of the desired tissue before implantation into the human body. In relation to cardiac tissues, these properties would include the ability to conduct action potentials, withstand systolic pressure, permit sufficient O2 and CO2penetration, sufficient vascularization to supply nutrients for cellular activity, surface topology that enables cellular communication, and more. As heart diseases and instances of myocardial infarction continue to rise worldwide, there is an increasing need for …
Therapeutic Approaches To Working With Perinatal Loss Clients: A Grounded Theory Study,
2023
University of New Orleans
Therapeutic Approaches To Working With Perinatal Loss Clients: A Grounded Theory Study, Heather H. Olivier
LSU New Orleans Theses and Dissertations
Perinatal loss (i.e., miscarriage, stillbirth, termination, and infant death) is commonly referred to in the literature as an invisible loss, non-loss, and even medical event. It is an ambiguous loss exhibiting the dialectical contradiction between the physical absence and psychological presence of the baby accompanied by disenfranchised grief, a reaction to a loss that is unacknowledged by society. Despite the likelihood of mental health clinicians working with clients who have experienced perinatal loss, there has yet to be a therapeutic model designed specifically for the unique grief and trauma reactions presented in this population. Existing grief models do not address …
Impacts Of Dietary Restriction On A Drosophila Model Of Werner Syndrome,
2023
University of Louisville
Impacts Of Dietary Restriction On A Drosophila Model Of Werner Syndrome, Eileen Sember
College of Arts & Sciences Senior Theses
Werner syndrome (WS) is an autosomal recessive disorder that results in premature aging and occurs in 1 in 1,000,0000 to 1 in 10,000,000 people. In humans, WS is the result of mutations that render the WRN gene, that contains a helicase and an exonuclease domain, non-functional. Currently, there is no cure for WS in humans, making dietary and lifestyle interventions attractive for increasing the quality and longevity of lives. Diet restriction (DR) has been shown to extend the lifespan of several model organisms, including Drosophila melanogaster, making it a strong candidate for WS treatment. In this thesis, mutant flies …
Seasonal Variation In Condition, Body Lipid, Reproductive Investment, And Diet In Brook Stickleback (Culaea Inconstans),
2023
Great Lakes Center at Buffalo State University
Seasonal Variation In Condition, Body Lipid, Reproductive Investment, And Diet In Brook Stickleback (Culaea Inconstans), Matthew P. Basista, Randal Snyder, Christopher Pennuto, Alicia Perez-Fuentetaja
Great Lakes Center Masters Theses
North-temperate fishes are subject to significant changes in abiotic and biotic conditions across seasons, which are likely reflected in temporal differences in energy dynamics, reproductive investment, and diet. This study explores seasonal changes in body lipid content, female reproductive investment (GSI), body condition (Fulton’s K), and diet in brook sticklebacks (Culaea inconstans) in Western New York. I expected body lipid content and body condition would decline during the breeding season reflecting energy expenditure for reproduction, and these parameters would increase in the summer and fall prior to the onset of winter. Based on previous studies, I also expected …
Unveiling The Ancestral Function Of A Neuroendocrine Regulator, Pou-I/Pit1: Insights From Gene Expression Analysis In The Sea Anemone Nematostella Vectensis,
2023
University of Arkansas, Fayetteville
Unveiling The Ancestral Function Of A Neuroendocrine Regulator, Pou-I/Pit1: Insights From Gene Expression Analysis In The Sea Anemone Nematostella Vectensis, Miguel Agostinho Pina Da Silva
Graduate Theses and Dissertations
Cnidaria (i.e., sea anemones, jellyfish, corals) and Bilateria (i.e., vertebrates, sea stars, fruit flies), are sister groups that diverged around 600 million years ago. Despite the long evolutionary time, many cellular differentiation mechanisms, cell types, tissues and behaviors are conserved. Such as neurons, mechanosensory hair cells, feeding behaviors, peristaltic movements, and sleep. Recent advances in genomics, molecular biology and microscopy have fueled an increased interest in understanding cnidarian nervous and neuroendocrine systems. Understanding the developmental mechanisms and the mode of operation of Cnidarian nervous systems helps to reconstruct the ancestral nervous system of the last common ancestor of Cnidaria and …
