Physiology Commons^™

The Effects Of Different Volume-Load On Sprint And Change Of Direction Performance, Damar K. Bobb

Electronic Theses and Dissertations

This study was designed to compare the effects of two different strength training protocols on sprint and change of direction (COD) performance in recreationally trained athletes. Participants were evaluated on maximal dynamic (1RM squat) and isometric (IMTP) strength, speed (30m sprint), and COD (5-0-5 test). The participants were divided into two groups (Low volume-heavy load group [LV], High volume-moderate load high-intensity endurance (HIE) group [HV]) after initial testing, for a 4-week training intervention using traditional and weightlifting derivative lifts. The training consisted of 5 sessions per week (3 sessions resistance training [RT], each about 40-50 mins; 2 sessions sprint & …

Metabolic Regulation Of Cardiac Fibroblast Phenotype And Function., Collin Kleis Wells

Electronic Theses and Dissertations

Cardiac fibroblasts are central effectors of cardiac repair after myocardial infarction (MI). In response to signaling cues, they differentiate to a range of phenotypes with robust capacities to synthesize and secrete extracellular matrix (ECM) and signaling molecules. Although activated fibroblast phenotypes are associated with pronounced changes in metabolism, it remains unclear how the metabolic network upholds the effector functions of fibroblasts in the post-infarcted heart. Here, we identified that critical enzymes in the phosphoenolpyruvate (PEP) cycle, i.e. pyruvate kinase muscle-2 (PKM2) and phosphoenolpyruvate carboxykinase-2 (PCK2), are elevated in the heart after MI and examined their role in regulating post-MI remodeling …

Using Livestreaming Technology To Answer Novel Questions About The Behavior And Physiological Ecology Of The Prairie Rattlesnake (Crotalus Viridis), Max C. Roberts

Master's Theses

Recent advances in remote monitoring technology are opening up new opportunities for developing innovative natural history and biological research methodologies. In particular, the emergence of livestreaming camera technology has made recording remote video of wild and secretive animals much easier and made it possible to collect data at extremely fine temporal resolutions. In 2024, Project RattleCam launched a livestreaming camera at a Prairie Rattlesnake (Crotalus viridis) den in Colorado. The goal of this work was to study Prairie Rattlesnake behavior 24-7 throughout the species’ active season with minimal human disturbance. Additionally, I used this system to study the …

Comparison Of Kinematic Outputs And Reliability Of Plug-In Gait Versus Conventional Gait Model 2 During Cycling, Erin Mccallister, Nicholas Russell

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 712-726, 2025. Motion analysis is used to measure proper bicycle fit, avoid injury, and improve cycling performance. Small changes in position can impact joint kinematics and risk for overuse injury. Concerns regarding the often-used biomechanical model Plug-in-Gait (PIG) resulted in the creation of Conventional Gait Model 2 (CGM2). This study aims to compare kinematic outputs of these two models for cycling biomechanics plus between-day reliability of each model. Thirty-five participants participated in two experimental sessions. PiG and CGM2 marker sets were applied, and data was collected while cycling between 80-90 rpm. Model outputs were …

Effects Of Aerobic Exercise On Physical Fitness In Obesity Using Fox Vs. Tanaka’S Maximum Heart Rate And Percentage Vs. Karvonen Methods, Maninthorn Rugbumrung, Tavarintorn Rukbumrung, Sittiwit Impanya, Adison Thurayot

International Journal of Exercise Science

International Journal of Exercise Science 18(8): 695-711, 2025. The intensity of aerobic exercise is influenced by maximum heart rate (MHR), which can be assessed through an incremental exercise test. However, this method requires specialized equipment and a level of fitness that individuals who are sedentary or overweight may lack. Therefore, estimating MHR using formulas is essential. Various methods exist to calculate MHR, but their effects on fitness in obese individuals remain unclear. This study aimed to investigate the effects of aerobic exercise using different intensity calculation methods, specifically comparing Fox's and Tanaka's maximum heart rate (MHR) equations, as well as …

Evaluation Of Physical, Mental, And Mechanical Aspects Of An Extreme Military Training Event: A Continuous Monitoring Approach, Tirthankar Chatterjee, Debojyoti Bhattacharyya, Roshani Meena

Journal of Human Performance in Extreme Environments

Soldiers receive extensive training at extremes of environments and simulated terrains to improve their battle efficiency. A study was designed to evaluate the actual cost of a military physical efficiency test consisting of several physically engaging activities to quantify physiological, mechanical, and subjective demands. Sixteen Indian soldiers participated in a military training session consisting of events such as a 5-km run, 4-m vertical rope climbing, a 2.75-m jump, a 60-m dash, and a 9-m horizontal rope climbing with 6.5 kg of equipment in a hot dry environment. Their physiological status was monitored continuously. National Aeronautics and Space Administration Task Load …

Accuracy Of Anthropometric Equations In Estimating Body Fat Percentage In Transgender Men Undergoing Gender-Affirming Hormone Therapy, Barbara Buosi, Yana Barros Hara, Rodolfo André Dellagrana, Rafael Martins Da Costa, Mateus Rossato

International Journal of Exercise Science

International Journal of Exercise Science 18(1): 686-694, 2025. Transgender people may opt for the use of sex steroids and, in some cases, hormone blockers, which can lead to changes in body fat distribution. The aim of this study was to verify the accuracy of anthropometric equations to estimate the body density (BD) of transgender men who are undergoing Gender-Affirming Hormone Therapy (GAHT). Four transgender men (25-32 years old), who had performed GAHT for at least six months and used the hormone testosterone cypionate participated in the study. The reference criteria for BD was air displacement plethysmography (ADP). In addition, BD …

Inter-Effort Recovery Intermittent Hypoxia And Force Parameters In Sprint Interval Exercise, Tarine Botta De Arruda, Felipe Alves Ribeiro Ms, Germano Marcolino Putti, Marcelo Papoti

International Journal of Exercise Science

International Journal of Exercise Science 18(3): 672-685, 2025. Performing training sessions in hypoxia leads to a decrease in effort quality. The inter-effort recovery intermittent hypoxia model seems to ensure training session performance. The aim of this study is to investigate the effects of sprint interval exercise under normoxic (NOR), continuous hypoxic (HYP), and inter-effort hypoxic (IEH) conditions on force parameters. Seven swimmers (age: 26.04 ± 4.64 years) volunteered and performed one session of the 10 × 30-s all-out tethered swimming efforts with 4-min passive recovery intervals for each condition. Considering the simulated altitude at F_iO₂ = 0.13 …

Role And Electrophysiological Properties Of Sexually Dimorphic Oxytocin Receptor Expressing Neurons In The Anteroventral Periventricular Nucleus Of The Female Mice, Armita Abdollahi Govar

LSU Doctoral Dissertations

Oxytocin is a neurohypophyseal hormone that plays a crucial role in regulating mother-infant bonding and maternal behavior. Oxytocin modulates sex-specific parental behaviors by binding to the oxytocin receptor (OXTR)-expressing neurons in the brain. This study investigates the sexually dimorphic OXTR neurons in the anteroventral periventricular nucleus (AVPV) to understand how oxytocin modulates behavior in females. Specifically, we explored the behavioral roles, neural projections, and intrinsic electrophysiological characteristics of these neurons in the female mice. Using immunohistochemistry revealed that the number of OXTR-expressing neurons was enhanced in postpartum females compared with virgin females, suggesting that these neurons are involved in female-specific …

Firefighters Versus Law Enforcement Officers: A Comparison Of Cardiovascular Disease Risk, Bethany C. Guerra, Steven E. Martin, Lisa C. Colvin, J. Jay Dawes, Matthew J. Mcallister, Drew E. Gonzalez

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 659-671, 2025. Firefighters (FFs) and law enforcement officers (LEOs) have heightened cardiovascular disease (CVD), with data suggesting that ≈45% of on-duty FF fatalities are related to CVD, while LEOs have a 1.7 times higher CVD prevalence than the general public. This study compared CVD risk biomarkers, fitness, and body composition between FFs and LEOs. Ninety-eight career, structural male FFs (age = 35.1±9.6 yrs; weight = 94.3±15.4 kg; height = 178.4±13.2 cm) and seventy-three career LEOs (age = 41.4±9.0 yrs; weight = 92.3±16.8 kg; height = 179.6±8.1 cm) from local departments were studied. Participants completed …

Identification Of Serum Exosome Proteins In Systemic Sclerosis With Interstitial Lung Disease By Aptamer Proteomics, Sonsoles Piera-Velazquez, Simon T. Dillon, Xuesong Gu, Towia A. Libermann, Sergio A. Jimenez

Jefferson Institute of Molecular Medicine Papers and Presentations

OBJECTIVE: A major unmet need for Systemic Sclerosis (SSc) clinical management is the absence of well validated biomarkers for early diagnosis of SSc-associated interstitial lung disease (SSc-ILD). The objective of this study was to identify proteins contained within serum exosomes that may serve as potential biomarkers to differentiate patients with Diffuse SSc without SSc-ILD from patients with Diffuse SSc with SSc-ILD employing aptamer-based proteomics.

METHODS: Serum exosomes were isolated from two cohorts of patients. The first cohort included 15 patients with Diffuse SSc without SSc-ILD and 14 patients with Diffuse SSc with SSc-ILD and the second cohort included 12 patients …

Investigating The Regulation Of The Hypothalamic-Pituitary-Interrenal Axis In Atlantic Sturgeon (Acipenser Oxyrinchus) Following An Acute Stressor, Liam Doherty, Ciarán A. Shaughnessy, Robert M. Dores

DU Undergraduate Research Journal Archive

This study investigated the response to acute stress in Atlantic sturgeon (Acipenser oxyrinchus) and HPI axis regulation of glucocorticoid production during stress by examining the expression of key genes―corticotropin-releasing hormone (crh), corticotropin-releasing hormone receptor (crhr), proopiomelanocortin (pomca/pomcb), melanocortin 2 receptor (mc2r), and steroidogenic acute regulatory protein (star)―that are associated with hypothalamus/pituitary/interrenal (HPI) axis of bony fishes. Additionally, tyrosine hydrogenase (th1 and th2) and phosphoenolpyruvate carboxykinase (pepck), found in catecholamine-producing cells in the head kidney of the sturgeon, were investigated as …

The Loss Of Opa1 Accelerates Intervertebral Disc Degeneration And Osteoarthritis In Aged Mice, Vedavathi Madhu, Miriam Hernandaz-Meadows, Ashley Coleman, Kimheak Sao, Kameron Inguito, Owen Haslam, Paige Boneski, Hiromi Sesaki, Ruteja Barve, John Collins, Makarand Risbud

Department of Orthopaedic Surgery Faculty Papers

Recent studies have highlighted the importance of mitochondria in NP cells and articular chondrocyte health. Since the understanding of mechanisms governing mitochondrial dynamics in these tissues is lacking, we investigated the role of OPA1, a mitochondrial fusion protein, in their homeostasis. OPA1 knockdown in NP cells altered mitochondrial size and cristae shape and increased the oxygen consumption rate. OPA1 governed the morphology of multiple organelles, including peroxisomes, early endosomes and cis-Golgi and loss resulted in the dysregulation of autophagy. Metabolic profiling and

Sedentary Behavior Patterns After Acl Reconstruction, David M. Werner, Liubov Arbeeva, Yvonne M. Golightly, Balarinivasa R. Sajja, Michael D. Rosenthal, Matthew Tao, Elizabeth Wellsandt

International Journal of Exercise Science

International Journal of Exercise Science 18(4): 636-658, 2025. Individuals after anterior cruciate ligament reconstruction (ACLR) are less physically active than their uninjured peers, but little is known about their sedentary behavior (SB). This study aimed to identify patterns of SB in individuals six and 18 months after ACLR. Eighteen individuals after ACLR wore accelerometers for one week during six- and 18-month post-operative assessments (83.3% female, 19.7±5.6 years old, BMI 23.9±kg/m²). The percentage of awake time spent in SB was estimated. A multilevel (two time points – six and 18 months), multidimensional (13 hours) functional principal component analysis generated …

Reliability Of A Linear Position Transducer During The Bench Press Across Three Segments, Jennifer Rivera, Edward Pelka, Ryan Gant, Anthony G. Pinzone, Emily C. Tagesen, Modesto A. Lebron, Adam R. Jajtner

International Journal of Exercise Science

International Journal of Exercise Science 18(2): 622-635, 2025. The purpose of this investigation was to determine inter-set and inter-session reliability of the HUMAC360 measures for duration (DUR), peak velocity (PV) and mean velocity (MV) across three segments of the bench press. Seventeen recreationally active adults participated in this investigation. During visit one, participants completed a bench press one-repetition maximum (1RM). Visits two and three consisted of two sets of three repetitions at 30%-, 50%-, 60%-, and 70 %-1RM. Segments were defined by dividing total displacement into equal thirds at the bottom (BOT), middle (MID) and top (TOP). Intraclass correlation coefficients …

Kinematic Analysis Of Olympic And Traditional Rowing Mechanics At Different Stroke Rates, Alfonso Penichet-Tomas, Sergio Calavia-Carvajal, Basilio Pueo, Lamberto Villalon-Gasch

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 610-621, 2025. Rowing requires strength, endurance, and technique, where stroke efficiency depends on body mechanics, movement sequencing, and stroke rate, which impact speed transfer. This cross-sectional study investigates the role of kinematic differences in stroke mechanics as a key component of performance analysis in Olympic and Traditional rowing. Thirteen elite national-level female rowers (age: 26.9 ± 5.1 years; body mass: 60.6 ± 6.9 kg; height: 166.7 ± 6.7 cm) performed three stroke-rate conditions on two ergometer setups: an Olympic rowing ergometer and a modified ergometer with a static seat replicating Traditional rowing. The stroke …

The Effect Of Breakfast On A Resistance Training Session And Response In Female Collegiate Athletes, Haley Roberts, Yvette Figueroa, Jennifer Bunn, Patrick Davis

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 591-609, 2025. Breakfast consumption has been shown to be an essential component to a healthy lifestyle in various populations, yet research in this area is limited among female athletes. This study aimed to examine the effect of breakfast consumption on collegiate female athletes during a resistance training session and their nutritional habits throughout the remainder of the day. Twenty-three female collegiate Division I athletes (basketball, volleyball, bowling, and soccer) during the offseason participated in this cross-over study. The study included three visits: baseline measures for heart rate (HR), blood glucose (BG), salivary cortisol (SC), …

Evolution Of Match Technical-Tactical Performance Indicators According To Age Category In Men's National Football Teams (World Cups 2003-2019), Sergio A. Caicedo-Parada, Enrique Ortega, Jose M. Palao

International Journal of Exercise Science

International Journal of Exercise Science 18(3): 575-590, 2025. Performance in football depends on different dynamic interactions between players that occur at technical, tactical, physical, psychological, or sociological levels. The objective of this study was to analyze the evolution of match technical-tactical performance indicators according to age category in men's national football teams (U-17, U-20 and senior). A non-experimental retrospective observational design was used. Variables studied were ball possession, goal chances, shots off target, shots on target, corner kicks, effectiveness; goals, offsides, fouls committed, yellow cards, red cards, and second yellow cards. Data were drawn from 917 matches (195 senior, 369 …

Advances In Bone And Orthopedics 2025 – 5th Edition, Jean-Philippe Berteau, Laurent Pujo-Menjouet, Hélène Follet, Aurélie Levillain

Publications and Research

This volume brings together selected works from the 2025 Bone and Orthopedics Interdisciplinary Symposium (BONITOS), underscoring our community’s ongoing commitment to advancing research in biomechanics, bone health, and orthopedic science. The symposium unites leading experts from around the world, fostering collaboration and the exchange of ideas across disciplines. Organized in partnership with the French-speaking Society of Biomechanics, the French National Institute of Health and Medical Research (INSERM), the University of Lyon, the College of Staten Island of the City University of New York (CUNY), and the American Association of Physical Therapists (APTA) – Brooklyn Staten Island Chapter, BONITOS 2025 represents …

The Effect Of Functional Training On Dynamic Knee Valgus Of Youth Soccer Players. A Pilot Study, Ole Tovar, Dóra Molnár, Badis Soussi, Ádám Uhlár, Tamás Horváth, Mira Ambrus

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 561-574, 2025. Knee injuries are very common in soccer players. High loads on the knee during landing or changes of direction can lead to a valgus shift of the knee, known as Dynamic Knee Valgus (DKV). Many studies have shown that a large shift in DKV is a predisposing factor for knee injuries and disease, such as anterior cruciate ligament injury (ACL), patellofemoral pain syndrome or osteoarthritis. Functional training could be a great tool to reduce DKV. Thus, in this pilot study, nine male youth soccer players (mean age: 16.4 ± 0.2 years) took …