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Articles 4081 - 4110 of 62458
Full-Text Articles in Public Affairs, Public Policy and Public Administration
Bridging The Gap: Analyzing Volunteerism Barriers To The International Humanitarian Ngos In Egypt, Heba Fouad
Bridging The Gap: Analyzing Volunteerism Barriers To The International Humanitarian Ngos In Egypt, Heba Fouad
Theses and Dissertations
In Egypt, volunteerism, within international humanitarian non-governmental organizations (NGOs), functions in distinctive characteristics influenced by, among other things, cultural, educational, and economic factors. NGOs face challenges and obstacles in attracting motivated volunteers, engaging and training volunteers, as well as managing the staff-volunteers relationship, and implementing adequate human resources (HR) policies and strategies. In this context, this thesis seeks to bridge the knowledge gap of volunteerism challenges in Egypt, delving deep into understanding the barriers existing within the international humanitarian NGOs that directly and indirectly influence its volunteer engagement levels. The thesis also aims to understand the successful implementation of policies …
Perspectives Of Juvenile Violence Prevention Programs, Tamlar D. Walton
Perspectives Of Juvenile Violence Prevention Programs, Tamlar D. Walton
Walden Dissertations and Doctoral Studies
The increase in violent behavior among individuals aged 12 to 19 prompted a nonprofit organization to consider adopting a more proactive approach to reduce such violence in the community while also expanding the range of services offered to address this concern. The organization leaders recognized the necessity of improving their knowledge in this area, prompting them to enlist the services of a research consultant who utilized a generic qualitative research method to explore juvenile violence prevention programs. This professional administrative study examined the experiences and perspectives of public servants who engaged with juvenile offenders, focusing on the influence of their …
Restoring School Librarians: Challenges And Strategies, Debrah E. Kachel
Restoring School Librarians: Challenges And Strategies, Debrah E. Kachel
Learning Hub
The article examines efforts to restore school librarian positions across eleven urban U.S. school districts, despite significant financial and administrative obstacles. It documents strategies used by district library leaders to advocate for staffing, funding, and policy changes, emphasizing equity in access to certified school librarians. Through structured interviews and analysis, the report highlights key barriers, advocacy methods, and funding mechanisms that have influenced school library staffing. The study's findings contribute to the ongoing discourse on educational equity and policy reform in K-12 library services.
Gender Inequality And Productivity Impact In Egypt, Hammad Elsaid Omar
Gender Inequality And Productivity Impact In Egypt, Hammad Elsaid Omar
The Undergraduate Research Journal
This study examines the relationship between gender inequality in Egypt's workforce and productivity across various sectors. Utilizing a comparative research design, the analysis employs quantitative data from sources such as the World Bank and the International Labor Organization. Key indicators of gender inequality—including the gender pay gap, the percentage of women in managerial positions, and female labor force participation rates—are correlated with productivity metrics like GDP per capita and productivity per employee (Figure 3). Findings reveal a strong negative correlation between the gender pay gap and productivity, with sectors exhibiting smaller pay disparities achieving higher productivity levels. Regression analysis indicates …
Behavioral Science-Based “Nudges” Could Increase Physical Activity Among Adolescents With Adhd, Hannah Patnaik, Andrew S. London, Kevin M. Antshel
Behavioral Science-Based “Nudges” Could Increase Physical Activity Among Adolescents With Adhd, Hannah Patnaik, Andrew S. London, Kevin M. Antshel
Population Health Research Brief Series
Children and adolescents with ADHD are more likely to exhibit difficulties in school, have higher rates of injuries and accidents and more family conflicts, and are at higher risk of depression and anxiety. Given the prevalence of ADHD and associated difficulties, there is a substantial need for effective ADHD treatment and symptom management. This brief summarizes findings from a recently completed pilot study testing the efficacy of behavioral interventions aimed at encouraging daily physical activity (i.e., steps measured with an activity tracker) among adolescents with ADHD in the Syracuse, NY area between March 2023 and June 2024. Results show that …
Insider Risks And The Evolving Role Of Executive Protection Professionals In Cybersecurity, Alan Saquella
Insider Risks And The Evolving Role Of Executive Protection Professionals In Cybersecurity, Alan Saquella
Publications
Insider risks have long been a critical concern in corporate security, traditionally encompassing threats from employees, contractors, or third-party vendors with access to sensitive information. However, as digital transformation accelerates, the convergence of physical and cyber threats has created new vulnerabilities. Executive protection (EP) professionals, historically tasked with safeguarding high-profile individuals from physical threats, now find themselves on the frontlines of combating cyber-criminal attacks. Expanding their skill sets to include cybersecurity awareness is no longer optional—it is a necessity.
This article explores insider risks, the growing need for executive protection professionals to adapt, and practical ways they can enhance their …
Criminal Justice Update - February 2025, Mia Agudelo
Criminal Justice Update - February 2025, Mia Agudelo
Criminal Justice Updates
The Criminal Justice Update is a monthly newsletter created by the Adams County Bar Foundation Fellow providing updates in criminal justice policy coming from Pennsylvania's courts and legislature as well as the US Supreme Court.
Contents:
- Updates from PA Governor's Office (no updates this month)
- Updates from the PA Legislature (no updates this month)
- Updates from the Courts
- U.S. Supreme Court: Criminal Law & Procedure
- PA Supreme Court: Criminal Law & Procedure
- PA Superior Court: Criminal Law & Procedure
Emergent Groups And The Informal Digital Emergent Response To Hurricane Florence In The United States, Andrew S. Pyle, Hillary Smith, Ryan P. Fuller
Emergent Groups And The Informal Digital Emergent Response To Hurricane Florence In The United States, Andrew S. Pyle, Hillary Smith, Ryan P. Fuller
Publications
Our study presents a thematic analysis of 1,582 posts from five digital emergent Facebook groups during Hurricane Florence, affecting North and South Carolina in the United States in 2018. We pose four research questions related to the formation and functioning of digital emergent groups during a disaster. Specifically, we examined how groups contributed to response efforts; messages developed across stages of the disaster; grassroots groups’ organized disaster response; and how proximity affected group functioning. Participants contributed to disaster response by sharing and seeking information and aid. Groups coordinated logistics; offered affirmation; and provided commentary and humor. Group members supported the …
Health Coverage And Educational Investments, Pragati, Tirthatanmoy Das
Health Coverage And Educational Investments, Pragati, Tirthatanmoy Das
Working Papers
Human capital theory posits that investments in health and education are complementary. Health investments boost education demand, thereby increasing educational expenditures. Drawing on this theory, this paper examines the impact of health coverage on three aspects of household educational investments: (a) the share of educational expenditures, (b) the level of educational spending, and (c) the probability of taking an educational loan. Using a health insurance scheme in India, this study employs a modified difference-in-difference strategy and two waves of the Indian Human Development Survey (2004-05 and 2011-12). The findings show that health insurance led to a 10 percent rise in …
The Feminization Of Deteriorated Labor Force Participation In Egypt: 1990 – 2024, Mennan Gamal Nour El Din
The Feminization Of Deteriorated Labor Force Participation In Egypt: 1990 – 2024, Mennan Gamal Nour El Din
Theses and Dissertations
The purpose of this thesis is to explain why female labor force participation deteriorated in quantity and in quality despite the recent rise in female educational attainment levels over the past three decades (1990 – 2024). On the one hand, labor participation declined, whereas on the other hand, female informal employment remains high in Egypt. This thesis dissertation utilizes a qualitative research methodology through both secondary data in the form of descriptive statistics on the phenomenon of female labor force participation as well as primary data in the form of six in-depth expert interviews with experts in the fields of …
Up-Island Council On Aging: Planning For The Future, Ceara Somerville, Caitlin E. Coyle
Up-Island Council On Aging: Planning For The Future, Ceara Somerville, Caitlin E. Coyle
Center for Social and Demographic Research on Aging Publications
This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA) within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Up-Island Council on Aging (UICOA). The goals of this project were to investigate the needs, interests, preferences, and opinions of Aquinnah, Chilmark, and West Tisbury residents age 50 or older by engaging the community regarding their experiences and needs relevant to the Council on Aging’s (UICOA’s) objective to identify and serve the needs of older residents of Up-island.
Amidst The Frenzy Over Deepseek Ai, Us Federal Science And Tech Policy Is A Mess Of Internal Contradictions, Yujia He
Patterson School of Diplomacy and International Commerce Faculty Publications
The release of the R1 model by the Chinese artificial intelligence (AI) company, DeepSeek, shocked the US tech industry. Yujia He writes that while DeepSeek’s model may not be quite as superior compared to its competitors as originally thought, the Trump administration has responded to its innovations by further pushing for US leadership in AI. Taking a close look at US research and development policy under the second Trump administration, however, shows the significant disconnect between rhetoric and policy. Federal funding freezes and reduced funding for the National Science Foundation could have dire long-term consequences for research and international cooperation …
Aging In Uxbridge: A Community Needs Assessment, Caitlin E. Coyle, Katherine Burnes, Ceara Somerville
Aging In Uxbridge: A Community Needs Assessment, Caitlin E. Coyle, Katherine Burnes, Ceara Somerville
Center for Social and Demographic Research on Aging Publications
This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA) within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Town of Uxbridge. The goals of this project were to investigate the interests, preferences, and opinions of Uxbridge’s residents aged 55 or older by engaging the community regarding their experiences and needs relevant to the Council on Aging’s (COA’s) and Senior Center objective to identify and serve the needs of all Uxbridge citizens 55 and older. The contents of this report are meant to inform the Town of Uxbridge, the …
A Visual Instrument For Military Public Affairs, Rose Di Trolio
A Visual Instrument For Military Public Affairs, Rose Di Trolio
Theses
This directed project is a visual guidebook that assists Missouri National Guard Soldiers, Airmen, and civilians onboarding within the Public Affairs Office and 70th Mobile Public Affairs Detachment. This guidebook serves as a tool for the creative-minded perspective to better understand materials such as the overall public affairs process, community relations, and social media creation and management. All the contents of this guidebook are directed from publicly-made information and labeled UNCLASSIFIED. This graphical guidebook uses vectors and images combined into one PDF file. Within the Military profession, it is typical and sometimes expected for members to relocate, deploy, or attend …
برنامج نافس في عامه الثالث: دراسة تحليلية في إطار السياسات العامة, Sara Almessabi
برنامج نافس في عامه الثالث: دراسة تحليلية في إطار السياسات العامة, Sara Almessabi
Theses
Nafis Program in its Third Year: A Public Policy Analysis
Emiratization in the United Arab Emirates (UAE) stands at the forefront of government priorities, with policymakers placing significant emphasis on it as a fundamental pillar for providing citizens with a dignified life and enhancing their participation across various economic sectors. Emiratis are considered integral contributors to driving their country's economic development. Recognizing this importance, the UAE government has focused its efforts since the country's establishment on enacting public policies that enable Emiratis to integrate into both the public and private labour markets. However, these policies have faced several challenges, most …
Peacebuilding At The San Diego-Tijuana Border: A Ground Level View, Rebeca Cazares-Adame Md, Mph, Andrew Blum Phd
Peacebuilding At The San Diego-Tijuana Border: A Ground Level View, Rebeca Cazares-Adame Md, Mph, Andrew Blum Phd
Kroc IPJ Research and Resources
This brief complements the work of researchers like Kleinfeld and Blattman by seeking to understand in a more inductive way the work of peacebuilders on the ground in Tijuana, a city experiencing systemic, chronic violence. Based on survey research and interviews conducted with those peacebuilders, the brief identifies insights that can help inform a peacebuilding field that includes and integrates work in conflict zones and non-conflict zones experiencing widespread violence. Developing this more integrated approach is particularly important at the moment as we move into President Trump’s second term and begin to see the impacts of his administration in the …
Childhood Sexual Abuse Among Asian American Adults: Prevalence, Cultural Barriers, And Mental Health Implications, Kruti S. Chaliawala, Liliana Rojas-Guyler
Childhood Sexual Abuse Among Asian American Adults: Prevalence, Cultural Barriers, And Mental Health Implications, Kruti S. Chaliawala, Liliana Rojas-Guyler
Dignity: A Journal of Analysis of Exploitation and Violence
Childhood sexual abuse represents a significant public health concern, particularly within minority populations, where adversities and complications are prevalent but understudied. This study aims to investigate the mental health of Asian American childhood sexual abuse survivors and explore the prevalence of childhood sexual abuse among Asian adults. A secondary analysis of the 2020 Behavioral Risk Factor Surveillance System (BRFSS) data was conducted, including a final sample of 1,894 Asian adults (0.16% of the total sample size of N = 401,958). Among these participants, 16.8% (n = 1,894) reported experiencing CSA. The most common forms of abuse were inappropriate touching …
Increasing Housing Stability Through State-Funded Community Mediation, Madhawa Palihapitiya, Karina Zeferino
Increasing Housing Stability Through State-Funded Community Mediation, Madhawa Palihapitiya, Karina Zeferino
Massachusetts Office of Public Collaboration Publications
The Massachusetts Housing Mediation Program (HMP), administered by the Massachusetts Office of Public Collaboration (MOPC) at the University of Massachusetts Boston (UMass Boston), remains a critical resource for addressing housing instability and homelessness across the Commonwealth. By offering free mediation services to tenants and landlords/property managers at every stage of a housing dispute, the program plays a pivotal role in fostering housing stability.
Established in FY2021 as part of the Eviction Diversion Initiative (EDI) to mitigate housing crises during the COVID-19 pandemic and coordinated through the Executive Office of Housing and Livable Communities (EOHLC), the HMP has continued …
The Jamaica Now Leadership Council: A Study Of Stakeholder Participation In The Revitalization Of Downtown Jamaica, Queens, Melva M. Miller
The Jamaica Now Leadership Council: A Study Of Stakeholder Participation In The Revitalization Of Downtown Jamaica, Queens, Melva M. Miller
Dissertations, Theses, and Capstone Projects
Urban revitalization in the United States has often been characterized by uneven community development, where marginalized communities bear the costs while receiving limited benefits. This dissertation examines how the dynamics of stakeholder participation impacts the practice of Community Economic Development (CED), focusing on the Jamaica Now Leadership Council (JNLC) as a case study. Formed to oversee the Jamaica Now Neighborhood Action Plan, the JNLC represents a model of inclusive, stakeholder-driven urban development aimed at addressing historical disinvestment and promoting equitable economic growth in Downtown Jamaica, Queens.
The study explores how power dynamics, stakeholder histories, and role expectations shape participation in …
Vote For The Ccrb In 2025: A Data Visualization Analysis Of Police Oversight Under Three Mayoral Administrations, Thomas Fagin
Vote For The Ccrb In 2025: A Data Visualization Analysis Of Police Oversight Under Three Mayoral Administrations, Thomas Fagin
Dissertations, Theses, and Capstone Projects
This project examines the relationship between mayoral administration and police oversight in New York City through an analysis of Civilian Complaint Review Board (CCRB) data from 2002 to 2024. Using interactive data visualizations, historical context, and annotations that delineate the trends within the data, the project illuminates how mayoral administrations have influenced the handling and outcomes of civilian complaints against police officers. This influence can be seen in policing policy as well as appointments to the board itself. The goal is to educate voters about the CCRB and the direct impact their choice for mayor has on police accountability through …
The U.S. Grand Strategy Toward The Pacific Islands, Angela Vasovic
The U.S. Grand Strategy Toward The Pacific Islands, Angela Vasovic
Dissertations, Theses, and Capstone Projects
The United States has recently placed its relations with the Pacific Islands, fourteen small states far out in the Pacific Ocean, on its high-priority diplomatic agenda. Although it has been interacting with the islands since the 1800s and had heavily relied on their cooperation during World War II, the importance of the islands waned in the eyes of the United States in the late twentieth and the beginning of the twenty first century as the country turned its attention to other regions of the world. However, in recent years, the U.S. has recognized the need to strengthen relations with the …
Whose Innovation? Philanthropic And School-Based Visions Of High School In The Xq Super School Competition, Brett G. Murphy
Whose Innovation? Philanthropic And School-Based Visions Of High School In The Xq Super School Competition, Brett G. Murphy
Dissertations, Theses, and Capstone Projects
The XQ Institute, funded by Laurene Powell Jobs’ Emerson Collective, launched a design competition in 2015 to find the most innovative high schools in the country. Their goal was to spark a movement that would revolutionize secondary school in the United States, a system they claimed was 100 years behind the times. Called the Super School Project, the winning ten teams each received $10 million. While XQ claims that the best ideas about high school reform come from communities and student voice, they also have funded selective ideas about “innovation,” including computer-based personalized learning. The organization’s efforts have grown in …
Why Are Fairness Concerns So Important? Lessons From A Last-Mile Transportation System, Yiwei Chen, Hai Wang
Why Are Fairness Concerns So Important? Lessons From A Last-Mile Transportation System, Yiwei Chen, Hai Wang
Research Collection School Of Computing and Information Systems
The Last-Mile Problem refers to the provision of travel service for passengers from the nearest public transportation node to the final destination. The Last-Mile Transportation System (LMTS), which has recently emerged, provides on-demand last-mile transportation service for passengers. We consider an LMTS that consists of two types of passengers, regular-type passengers and special-type passengers (e.g., seniors, disabled people). The valuation of the last-mile service for special-type passengers is statistically higher than the one for regular-type passengers. Passengers incur disutility from waiting for the last-mile service. In this paper, we explore two fairness constraints on special-type passengers: (1) the fare for …
Figg At 5: An Update On Us Public Perspectives On Forensic Investigative Genetic Genealogy Five Years After Its Introduction To Criminal Investigations, Christi J Guerrini, Jill O Robinson, Mohamed I Elsaid, Whitney Bash Brooks, Ariel Levchenko, Stephanie M Fullerton, Sara Huston, Norah L Crossnohere, John F P Bridges, Jacklyn M Dahlquist, Louiza Kalokairinou, Diana Madden, Cece Moore, Amy L Mcguire
Figg At 5: An Update On Us Public Perspectives On Forensic Investigative Genetic Genealogy Five Years After Its Introduction To Criminal Investigations, Christi J Guerrini, Jill O Robinson, Mohamed I Elsaid, Whitney Bash Brooks, Ariel Levchenko, Stephanie M Fullerton, Sara Huston, Norah L Crossnohere, John F P Bridges, Jacklyn M Dahlquist, Louiza Kalokairinou, Diana Madden, Cece Moore, Amy L Mcguire
Center for Medical Ethics and Health Policy Staff Publications
In 2018, after law enforcement announced it had used a technique called forensic investigative genetic genealogy (FIGG) to identify the Golden State Killer, we conducted a U.S. general population survey and found most respondents supported using FIGG to solve violent crimes. Since then, FIGG has helped close hundreds of criminal cases, but it also has weathered controversies. On FIGG's fifth anniversary, we conducted an expanded, follow-up survey with U.S.-based participants to determine if public opinion had changed and found continued support for FIGG across most applications. The same proportion (91 %) of respondents in the 2018 and 2023 surveys endorsed …
Improving Individualized Rhabdomyosarcoma Prognosis Predictions Using Somatic Molecular Biomarkers, Mark Zobeck, Javed Khan, Rajkumar Venkatramani, M Fatih Okcu, Michael E Scheurer, Philip J Lupo
Improving Individualized Rhabdomyosarcoma Prognosis Predictions Using Somatic Molecular Biomarkers, Mark Zobeck, Javed Khan, Rajkumar Venkatramani, M Fatih Okcu, Michael E Scheurer, Philip J Lupo
Center for Medical Ethics and Health Policy Staff Publications
Purpose: Molecular markers increasingly influence risk-stratified treatment selection for pediatric rhabdomyosarcoma (RMS). This study aims to integrate molecular and clinical data to produce individualized prognosis predictions that can further improve treatment selection.
Methods: Clinical variables and somatic mutation data for 20 genes from 641 patients with RMS in the United Kingdom and the United States were used to develop three Cox proportional hazard models for predicting event-free survival (EFS). The Baseline Clinical (BC) model included treatment location, age, fusion status, and risk group. The Gene Enhanced 2 (GE2) model added TP53 and MYOD1 mutations to the BC predictors. The Gene …
Longitudinal Phage-Bacteria Dynamics In The Early Life Gut Microbiome, Michael J Tisza, Richard E Lloyd, Kristi Hoffman, Daniel P Smith, Marian Rewers, Sara J Javornik Cregeen, Joseph F Petrosino
Longitudinal Phage-Bacteria Dynamics In The Early Life Gut Microbiome, Michael J Tisza, Richard E Lloyd, Kristi Hoffman, Daniel P Smith, Marian Rewers, Sara J Javornik Cregeen, Joseph F Petrosino
Center for Medical Ethics and Health Policy Staff Publications
Microbial colonization of the human gut occurs soon after birth, proceeds through well-studied phases and is affected by lifestyle and other factors. Less is known about phage community dynamics during infant gut colonization due to small study sizes, an inability to leverage large databases and a lack of appropriate bioinformatics tools. Here we reanalysed whole microbial community shotgun sequencing data of 12,262 longitudinal samples from 887 children from four countries across four years of life as part of the The Environmental Determinants of Diabetes in the Young (TEDDY) study. We developed an extensive metagenome-assembled genome catalogue using the Marker-MAGu pipeline, …
Revisiting What Constitutes A Neglected Tropical Disease?, Paul J Brindley, Peter J Hotez, Shaden Kamhawi
Revisiting What Constitutes A Neglected Tropical Disease?, Paul J Brindley, Peter J Hotez, Shaden Kamhawi
Center for Medical Ethics and Health Policy Staff Publications
PLOS Neglected Tropical Diseases (PLOS NTDs) publishes research devoted to pathogenesis and other clinical aspects, epidemiology, prevention, diagnosis, treatment, and control of the neglected tropical diseases (NTDs), as well as work relevant to public health policy. We define NTDs as poverty-promoting infectious diseases that can negatively impact the quality of life in rural areas and poor urban areas of low- and middle-income countries but which can also affect specific communities within high-income countries. The poverty-inducing effects of the NTDs operate by impairing child health and development, pregnancy outcomes for both mother and child, worker productivity, and quality of life. The …
Resilience And Coping: A Qualitative Analysis Of Cognitive And Behavioral Factors In Adults With Osteogenesis Imperfecta, Hannah E Cho, Whitney S Shepherd, Gianna M Colombo, Andrew D Wiese, W Conor Rork, Kristin M Kostick, Dianne Nguyen, Members Of The Bbdc, Chaya N Murali, Marie-Eve Robinson, Sophie C Schneider, Justin H Qian, Brendan Lee, V Reid Sutton, Eric A Storch
Resilience And Coping: A Qualitative Analysis Of Cognitive And Behavioral Factors In Adults With Osteogenesis Imperfecta, Hannah E Cho, Whitney S Shepherd, Gianna M Colombo, Andrew D Wiese, W Conor Rork, Kristin M Kostick, Dianne Nguyen, Members Of The Bbdc, Chaya N Murali, Marie-Eve Robinson, Sophie C Schneider, Justin H Qian, Brendan Lee, V Reid Sutton, Eric A Storch
Center for Medical Ethics and Health Policy Staff Publications
Purpose: The aim of this qualitative study was to investigate resilience among adults with Osteogenesis Imperfecta (OI).
Materials and methods: Semi-structured interviews were conducted with 15 adults with OI. Transcripts were coded and subsequently abstracted, yielding themes specific to resilience and coping. Interview guides covered broad topics including pain challenges specific to OI, mental health issues related to OI, and priorities for future interventions for individuals with OI.
Results: Participants described resilience in the context of OI as the ability to grow from adversity, adapt to challenges resulting from OI-related injuries, and find identities apart from their condition. Psychological coping …
Ethical Governance For Genomic Data Science In The Cloud, Vasiliki Rahimzadeh, Sarah C Nelson, Adrian Thorogood, Jonathan Lawson, Stephanie M Fullerton
Ethical Governance For Genomic Data Science In The Cloud, Vasiliki Rahimzadeh, Sarah C Nelson, Adrian Thorogood, Jonathan Lawson, Stephanie M Fullerton
Center for Medical Ethics and Health Policy Staff Publications
Cloud platforms offer distinct advantages, but questions remain about how to ethically and efficiently manage human genomic data in the cloud. Data governance needs to be adapted to ensure transparency and security for research participants, as well as equitable and sustainable access for researchers.
Incidence And Survival Of Children And Adolescents With Wilms Tumor, United States, 2001-2020, Andres F Espinoza, Ekene Onwuka, David A Siegel, Shifan Dai, Sanjeev A Vasudevan, Michael E Scheurer, Philip J Lupo
Incidence And Survival Of Children And Adolescents With Wilms Tumor, United States, 2001-2020, Andres F Espinoza, Ekene Onwuka, David A Siegel, Shifan Dai, Sanjeev A Vasudevan, Michael E Scheurer, Philip J Lupo
Center for Medical Ethics and Health Policy Staff Publications
Background: Wilms tumor (WT) is the most common pediatric malignancy of the kidney. Past studies describing WT incidence and survival used surveillance data with < 30% of the US population. We evaluated differences in WT incidence and survival comparing demographic groups and tumor characteristics.
Methods: We analyzed new cases of WT among patients aged < 20 years at diagnosis by using incidence data from US Cancer Statistics (USCS) for 2003-2020 and 5-year relative survival (RS) data from the National Program of Cancer Registries (NPCR) for 2001-2019. To assess incidence trends, average annual percent change (AAPC) was calculated by using joinpoint regression. Relative survival (RS) and all-cause survival were calculated overall and by demographic and clinical variables.
Results: During 2003-2020, 8218 cases of WT were reported in USCS, which represented an age-adjusted incidence rate of 5.7 cases per million. Rates were the highest among females (6.3), children aged 0-4 years (17.2), and non-Hispanic Black patients (7.1). Overall, trends remained stable (AAPC = -0.4, 95% CI: -1.4 to 0.4). Among 7567 cases of WT in NPCR, 5-year RS was 92.6%. Patients with the lowest …