Open Access. Powered by Scholars. Published by Universities.®
Public Affairs, Public Policy and Public Administration Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Public Policy (10986)
- Business (8963)
- Sociology (8665)
- Peace and Conflict Studies (7929)
- Arts and Humanities (7493)
-
- Economics (7436)
- Political Science (7378)
- Law (7094)
- Defense and Security Studies (6503)
- Public Administration (5663)
- Medicine and Health Sciences (5548)
- Physical Sciences and Mathematics (5360)
- Education (5355)
- Health Policy (4805)
- Social Policy (4514)
- Urban Studies (4224)
- International and Area Studies (4217)
- Public Affairs (4143)
- Urban Studies and Planning (4123)
- Transportation (4092)
- Environmental Policy (3999)
- Other Public Affairs, Public Policy and Public Administration (3751)
- History (3631)
- Public Health (3296)
- Environmental Sciences (3232)
- Social Welfare (3166)
- Education Policy (3130)
- Growth and Development (3078)
- Institution
-
- James Madison University (3532)
- Portland State University (3401)
- Western Kentucky University (2739)
- University of Nebraska - Lincoln (2078)
- Walden University (1758)
-
- University of Massachusetts Boston (1601)
- University of Nevada, Las Vegas (1512)
- University of Nebraska at Omaha (1492)
- Universitas Indonesia (1306)
- University of Colorado Law School (1208)
- Old Dominion University (1194)
- World Maritime University (1190)
- Singapore Management University (1144)
- Syracuse University (1106)
- Chinese Academy of Sciences (1065)
- US Army War College (869)
- San Jose State University (866)
- SIT Graduate Institute/SIT Study Abroad (852)
- Embry-Riddle Aeronautical University (848)
- Grand Valley State University (787)
- University of Kentucky (779)
- Western Michigan University (768)
- Liberty University (759)
- City University of New York (CUNY) (758)
- Valparaiso University (738)
- Morehead State University (691)
- Nova Southeastern University (682)
- University of Arkansas, Fayetteville (671)
- University of Denver (656)
- Yale University (575)
- Keyword
-
- Kentucky (2232)
- Infrastructure (2089)
- Industry (2069)
- Journal (1961)
- CISR (1296)
-
- Mine Action (1281)
- Economic Development (1257)
- Economic development (1216)
- JMU (1197)
- ERW (888)
- DDAS (849)
- United States (832)
- Education (700)
- AP (634)
- Policy (631)
- Portland (Or.) -- Politics and government -- Periodicals (557)
- Urban policy -- Oregon -- Portland -- Periodicals (557)
- Portland (Or.) -- Social conditions -- Periodicals (555)
- Newspaper (545)
- UNA (545)
- Florence (543)
- Flor-Ala (540)
- Florala (540)
- ERW Clearance (533)
- Human rights (514)
- Afghanistan (508)
- COVID-19 (467)
- Terrorism (464)
- 9th Infantry Division Association (434)
- Public policy (434)
- Publication Year
- Publication
-
- The Journal of Conventional Weapons Destruction (1981)
- Walden Dissertations and Doctoral Studies (1692)
- Global CWD Repository (1444)
- Bulletin of Chinese Academy of Sciences (Chinese Version) (1065)
- World Maritime University Dissertations (929)
-
- The Foundation Review (773)
- Independent Study Project (ISP) Collection (744)
- Publications (732)
- The Cresset (archived issues) (724)
- City Club of Portland (610)
- New England Journal of Public Policy (609)
- Theses and Dissertations (604)
- International Bulletin of Political Psychology (593)
- Muthanna Journal of Administrative and Economics Sciences (571)
- Morehead State Press Release Archive, 1961 to the Present (567)
- The US Army War College Quarterly: Parameters (550)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (547)
- Mineta Transportation Institute (540)
- The Journal of Sociology & Social Welfare (531)
- Journal of Financial Crises (476)
- The Journal of Social Encounters (456)
- Human Rights & Human Welfare (454)
- Electronic Theses and Dissertations (452)
- The Octofoil (434)
- Institute for Veterans and Military Families (424)
- MPA/MPP/MPFM Capstone Projects (424)
- Faculty Publications and Presentations (419)
- Kesmas (412)
- Dissertations and Theses (373)
- Center for Medical Ethics and Health Policy Staff Publications (366)
- Publication Type
Articles 11251 - 11280 of 62484
Full-Text Articles in Public Affairs, Public Policy and Public Administration
Infrared Thermography In The Built Environment: A Multi-Scale Review, Miguel Martin, Adrian Chong, Filip Biljecki, Clayton Miller
Infrared Thermography In The Built Environment: A Multi-Scale Review, Miguel Martin, Adrian Chong, Filip Biljecki, Clayton Miller
Research Collection College of Integrative Studies
The paper presents a review on major contributions in infrared thermography to study the built environment at multiple scales. To elaborate the review, hundreds of studies conducted between the 1980s and 2020s were first selected based on their relevance to the scope. Afterward, the most relevant contributions were classified and chronologically sorted. From the classification, it is observed that most reviewed studies were conducted to evaluate the thermal performance of buildings or detect their defects using images collected by an infrared camera. At the same time, a considerable number of studies used thermal images obtained by a satellite to observe …
Desert Arcologies And Path Dependencies, Sayd Randle
Desert Arcologies And Path Dependencies, Sayd Randle
Research Collection College of Integrative Studies
In Phoenix, Arizona last year, the local high temperature topped 100 degrees Fahrenheit on 145 days, a new record. Of those 145, 53 days saw top temperatures above 110 and 14 days exceeded 115 – also new peaks. Taken together, these numbers strongly suggest that to live out 2020 in Phoenix was to inhabit an environment sliding towards a painful, and perhaps even hellish, new baseline. Of course, numbers are known to occlude at least as much as they reveal. But in the case of Arizona’s largest metropolitan area, they’re useful for framing a certain conventional wisdom about the place: …
2022 September, Morehead State University. Office Of Communications & Marketing.
2022 September, Morehead State University. Office Of Communications & Marketing.
Morehead State Press Release Archive, 1961 to the Present
Press releases for September of 2022.
Individual Perceptions Of Climate Anomalies And Collective Action: Evidence From An Artefactual Field Experiment In Malaysian Borneo, Terry Van Gevelt, T. Zamanb, K.N. Chanc, M.M. Bennettd
Individual Perceptions Of Climate Anomalies And Collective Action: Evidence From An Artefactual Field Experiment In Malaysian Borneo, Terry Van Gevelt, T. Zamanb, K.N. Chanc, M.M. Bennettd
Research Collection College of Integrative Studies
We explore the effect of individual perceptions of climate anomalies on collective action within a context of environmental complexity and uncertainty. To do so, we construct two competing propositions that are theoretically robust but with very different real-world implications. Our first proposition suggests that collective action to adapt to climate change is likely to be more effective when perceptions of climate anomalies converge within a community. Our second proposition suggests the opposite: that convergence is likely to hinder adaptation behaviour. We use a community co-designed measure of perceptions and an artefactual field experiment to test our propositions and explore the …
Learning To Solve Multiple-Tsp With Time Window And Rejections Via Deep Reinforcement Learning, Rongkai Zhang, Cong Zhang, Zhiguang Cao, Wen Song, Puay Siew Tan, Jie Zhang, Bihan Wen, Justin Dauwels
Learning To Solve Multiple-Tsp With Time Window And Rejections Via Deep Reinforcement Learning, Rongkai Zhang, Cong Zhang, Zhiguang Cao, Wen Song, Puay Siew Tan, Jie Zhang, Bihan Wen, Justin Dauwels
Research Collection School Of Computing and Information Systems
We propose a manager-worker framework (the implementation of our model is publically available at: https://github.com/zcaicaros/manager-worker-mtsptwr) based on deep reinforcement learning to tackle a hard yet nontrivial variant of Travelling Salesman Problem (TSP), i.e. multiple-vehicle TSP with time window and rejections (mTSPTWR), where customers who cannot be served before the deadline are subject to rejections. Particularly, in the proposed framework, a manager agent learns to divide mTSPTWR into sub-routing tasks by assigning customers to each vehicle via a Graph Isomorphism Network (GIN) based policy network. A worker agent learns to solve sub-routing tasks by minimizing the cost in terms of both …
Damage Detection And Damage Localization In Bridges With Low-Density Instrumentations Using The Wave-Method: Application To A Shake-Table Tested Bridge, Mehran Rahmani, Xintong Ji, Sovann Reach Kiet
Damage Detection And Damage Localization In Bridges With Low-Density Instrumentations Using The Wave-Method: Application To A Shake-Table Tested Bridge, Mehran Rahmani, Xintong Ji, Sovann Reach Kiet
Mineta Transportation Institute
This study presents a major development to the wave method, a methodology used for structural identification and monitoring. The research team tested the method for use in structural damage detection and damage localization in bridges, the latter being a challenging task. The main goal was to assess capability of the improved method by applying it to a shake-table-tested prototype bridge with sparse instrumentation. The bridge was a 4-span reinforced concrete structure comprising two columns at each bent (6 columns total) and a flat slab. It was tested to failure using seven biaxial excitations at its base. Availability of a robust …
Fueling Green Connections: Networked Policy Instrument Choices For Sustainability Regulation, Ishani Mukherjee
Fueling Green Connections: Networked Policy Instrument Choices For Sustainability Regulation, Ishani Mukherjee
Research Collection School of Social Sciences
This paper presents a policy network analysis study that examines policy subsystem interconnectedness and cohesion, to explore three constituent regulatory policy instruments that have a combined impact on governing sustainability. The network surrounding the environmental sustainability of biodiesel policy in Indonesia is marked by high interconnectedness and relatively weaker cohesion, properties that impact how policy solutions are formulated through policy actor interactions and define prevailing policy formulation styles. Using primary policy network data on 46 organizations and the review of national regulations, laws, and directives, this paper tests established hypotheses on how instruments that are formulated within the same policy …
Access To Power: Electricity And The Infrastructural State In Pakistan, Ijlal Naqvi
Access To Power: Electricity And The Infrastructural State In Pakistan, Ijlal Naqvi
Research Collection School of Social Sciences
Pakistan would desperately like to produce enough electricity, but it usually doesn’t. This is the rare issue on which government and private sector can unite, and it is the cause of suffering for rich and poor alike across the entirety of the country. Despite prioritization by successive governments, targeted reforms shaped by international development actors, and featuring prominently in Chinese Belt and Road Investments, the Pakistani power sector still stifles economic and social life across the country. This book explores state capacity in Pakistan by following the material infrastructure of electricity across the provinces and down into cities and homes. …
Advancing Philanthropic Strategy Through Evaluative Thinking: One Foundation’S Approach, Christine Baker, Margaret Eigsti, Kathryn Racine, Laurence O’Connell
Advancing Philanthropic Strategy Through Evaluative Thinking: One Foundation’S Approach, Christine Baker, Margaret Eigsti, Kathryn Racine, Laurence O’Connell
The Foundation Review
The Sisters of Charity Foundation of Cleveland supports Catholic sisters and their ministries in northeast Ohio through the grantmaking, partnership, capacitybuilding, and evaluation efforts of its Catholic Sisters Program Area. The decline of sisters actively engaged in ministry, due both to their rising median age and a decades-long decline in their overall numbers, called for a reconsideration and likely revision of the CSPA existing theory of change.
Unlike other strategic approaches at the foundation, such as ending homelessness or improving health equity, transitioning from sister-led to lay-led leadership of ministries remained largely unexplored: Basic research was lacking, and model practices …
Engaging Community To Build A Community Dashboard, Tanya Upthegrove Gregory, Liz Gordillo
Engaging Community To Build A Community Dashboard, Tanya Upthegrove Gregory, Liz Gordillo
The Foundation Review
The Ruth Mott Foundation’s mission is to advocate, stimulate, and support community vitality in our community of Flint, Michigan. The goal of the foundation’s 2016–2025 strategic plan is that residents of north Flint neighborhoods create and sustain opportunities to contribute and thrive. As a place-based grantmaker, the foundation uses community-level data internally to establish baseline data. Those data, in combination with local relationships and knowledge of other community initiatives, guide the foundation’s grantmaking strategy in the community’s context and assist with data-driven decision-making. Externally, the dashboard supports community engagement through access to local data. The foundation partnered with the Dorothy …
The Yin And Yang Of Equity-Centered Philanthropy, Douglas Easterling, Laura Mcduffee, Sabina Gesell
The Yin And Yang Of Equity-Centered Philanthropy, Douglas Easterling, Laura Mcduffee, Sabina Gesell
The Foundation Review
Foundations face two competing imperatives when they commit to advancing equity. On the one hand, they are counseled to support and follow the lead of community-based groups that are on the front lines of social change. On the other hand, they are also being challenged to use their power and influence to act boldly to change inequitable structures, policies, and institutions. These two orientations, yin and yang, can take a foundation in different directions and thus cause confusion and internal conflict.
The challenge for a foundation is to balance and integrate the two orientations into a comprehensive and effective approach …
Media Relations Strategies Of Philanthropic Foundations: A Longitudinal Analysis Of News Releases Produced By Top U.S. Foundations, Richard D. Waters, Giselle Auger, Kelly Husted
Media Relations Strategies Of Philanthropic Foundations: A Longitudinal Analysis Of News Releases Produced By Top U.S. Foundations, Richard D. Waters, Giselle Auger, Kelly Husted
The Foundation Review
Given their role in funding programs and services provided by nonprofit organizations, foundations have a critical role as advocates for social change. However, grant money is by itself not enough to create that change. Agenda-setting theory highlights the critical role of organizations in bringing change issues to the attention of the media and, therefore, the public. This article uses content analysis to compare two sets of a random sample of news releases from 20 of the largest foundations in the United States. The two sets are seven years apart, from 2014 and 2021, to allow comparison of the maturation of …
The Soft Stuff Doesn’T Have To Be Hard: Foundation Investments In Grantee Workers Are Necessary, Valuable, And Measurable, Rusty Stahl
The Foundation Review
There is an urgent need for funder investments in the ability of grantee nonprofit organizations to support their staff. Such investments, when done well, can yield significant value for individuals, organizations, and fields of work or movements. Furthermore, the value of these investments can be evaluated and communicated.
This article explores the reasons for and implications of the inadequate response by funders, offers a path forward for designing investments in grantee staff, and documents how funders can capture and communicate the value of these “talent investments.”
Powerful myths serve as barriers to widespread funder investment in grantee staff, and the …
Book Review: In Defence Of Philanthropy, Nabih Haddad
Book Review: In Defence Of Philanthropy, Nabih Haddad
The Foundation Review
No abstract provided.
Learning As We Go: How Emergent Process Supports Sustainable Community And Philanthropic Change, Elizabeth Myrick, Rachel Mosher-Williams, Laurie Zierer
Learning As We Go: How Emergent Process Supports Sustainable Community And Philanthropic Change, Elizabeth Myrick, Rachel Mosher-Williams, Laurie Zierer
The Foundation Review
Beginning in 2014, PA Humanities, one of 56 state and territorial humanities councils across the country, drew upon the work of Orton Family Foundation to deploy the Community Heart & Soul method, which centers community planning and civic engagement around connecting people to each other, and to the many assets of the places they live, through individual storytelling and collective narrative building.
Between 2015 and 2018, PA Humanities awarded matching grants to three locations in Pennsylvania — Greater Carlisle, Meadville, and Williamsport — to pilot PA Heart & Soul, a humanities-based, resident-driven community planning process that cultivates a shared sense …
Editorial, Teresa R. Behrens
Will Anti-Vaccine Activism In The Usa Reverse Global Goals?, Peter J Hotez
Will Anti-Vaccine Activism In The Usa Reverse Global Goals?, Peter J Hotez
Center for Medical Ethics and Health Policy Staff Publications
In the time of the COVID-19 pandemic, anti-vaccine activism in the USA accelerated, amplified and formed an alliance with political groups and even extremists. An organized, well-funded and empowered anti-science movement now threatens to spill over and threaten all childhood immunizations in the USA and globally.
Change During Cognitive And Exposure Phases Of Cognitive-Behavioral Therapy For Autistic Youth With Anxiety Disorders, Andrew G Guzick, Sophie C Schneider, Philip C Kendall, Jeffrey J Wood, Connor M Kerns, Brent J Small, Ye Eun Park, Sandra L Cepeda, Eric A Storch
Change During Cognitive And Exposure Phases Of Cognitive-Behavioral Therapy For Autistic Youth With Anxiety Disorders, Andrew G Guzick, Sophie C Schneider, Philip C Kendall, Jeffrey J Wood, Connor M Kerns, Brent J Small, Ye Eun Park, Sandra L Cepeda, Eric A Storch
Center for Medical Ethics and Health Policy Staff Publications
Objective: To evaluate improvement during the (a) cognitive and (b) exposure therapy phases of cognitive-behavioral therapy (CBT) for autistic youth with anxiety disorders.
Method: Participants were 148 autistic youth (aged 7-13; 77% male; 64% White) with clinically significant anxiety who were randomized to standard or adapted CBT. Clinician-rated anxiety severity was recorded at each appointment. Trajectories of change during (a) the cognitive phase and (b) the exposure phase of treatment were analyzed using piecewise multilevel modeling.
Results: Compared to the psychoeducation and cognitive therapy phases, the exposure phase corresponded with significantly more rapid symptom reduction, b = -.11, 95% CI …
High Prevalence Of Osteopathy In Chronic Pancreatitis: A Cross-Sectional Analysis From The Proceed Study, Phil A Hart, Dhiraj Yadav, Liang Li, Savi Appana, William Fisher, Evan Fogel, Chris E Forsmark, Walter G Park, Stephen Pandol, Mark D Topazian, Stephen K Van Den Eden, Santhi Swaroop Vege, David Bradley, Jose Serrano, Darwin L Conwell
High Prevalence Of Osteopathy In Chronic Pancreatitis: A Cross-Sectional Analysis From The Proceed Study, Phil A Hart, Dhiraj Yadav, Liang Li, Savi Appana, William Fisher, Evan Fogel, Chris E Forsmark, Walter G Park, Stephen Pandol, Mark D Topazian, Stephen K Van Den Eden, Santhi Swaroop Vege, David Bradley, Jose Serrano, Darwin L Conwell
Center for Medical Ethics and Health Policy Staff Publications
Background & aims: Chronic pancreatitis (CP) is associated with osteopathy (osteoporosis or osteopenia). However, existing literature is mostly limited to retrospective or administrative studies that have not clearly defined the prevalence and risk factors. Our aim was to identify patient- and disease-related associations with osteopathy in a prospective cohort study of CP.
Methods: We studied 282 subjects with definitive CP enrolled in the PROCEED study who had a baseline dual-energy X-ray absorptiometry (DXA) scan. Osteopenia and osteoporosis were defined using the lowest T-scores. Clinical data were collected using standardized case report forms. Comparisons were performed with a multivariate logistic regression …
Recommendations For Whole Genome Sequencing In Diagnostics For Rare Diseases, Erika Souche, Sergi Beltran, Erwin Brosens, John W Belmont, Magdalena Fossum, Olaf Riess, Christian Gilissen, Amin Ardeshirdavani, Gunnar Houge, Marielle Van Gijn, Jill Clayton-Smith, Matthis Synofzik, Nicole De Leeuw, Zandra C Deans, Yasemin Dincer, Sebastian H Eck, Saskia Van Der Crabben, Meena Balasubramanian, Holm Graessner, Marc Sturm, Helen Firth, Alessandra Ferlini, Rima Nabbout, Elfride De Baere, Thomas Liehr, Milan Macek, Gert Matthijs, Hans Scheffer, Peter Bauer, Helger G Yntema, Marjan M Weiss
Recommendations For Whole Genome Sequencing In Diagnostics For Rare Diseases, Erika Souche, Sergi Beltran, Erwin Brosens, John W Belmont, Magdalena Fossum, Olaf Riess, Christian Gilissen, Amin Ardeshirdavani, Gunnar Houge, Marielle Van Gijn, Jill Clayton-Smith, Matthis Synofzik, Nicole De Leeuw, Zandra C Deans, Yasemin Dincer, Sebastian H Eck, Saskia Van Der Crabben, Meena Balasubramanian, Holm Graessner, Marc Sturm, Helen Firth, Alessandra Ferlini, Rima Nabbout, Elfride De Baere, Thomas Liehr, Milan Macek, Gert Matthijs, Hans Scheffer, Peter Bauer, Helger G Yntema, Marjan M Weiss
Center for Medical Ethics and Health Policy Staff Publications
In 2016, guidelines for diagnostic Next Generation Sequencing (NGS) have been published by EuroGentest in order to assist laboratories in the implementation and accreditation of NGS in a diagnostic setting. These guidelines mainly focused on Whole Exome Sequencing (WES) and targeted (gene panels) sequencing detecting small germline variants (Single Nucleotide Variants (SNVs) and insertions/deletions (indels)). Since then, Whole Genome Sequencing (WGS) has been increasingly introduced in the diagnosis of rare diseases as WGS allows the simultaneous detection of SNVs, Structural Variants (SVs) and other types of variants such as repeat expansions. The use of WGS in diagnostics warrants the re-evaluation …
Hispanics And Latinos In The Military: The Path From Service To Veteran Entrepreneurship, Rosalinda V. Maury, Mirza Tihic, Adam Pritchard
Hispanics And Latinos In The Military: The Path From Service To Veteran Entrepreneurship, Rosalinda V. Maury, Mirza Tihic, Adam Pritchard
Institute for Veterans and Military Families
This brief provides highlights from the 2021 National Survey of Military-Affiliated Entrepreneurs (NSMAE) focusing on Hispanic, Latino/a/x, or Spanish origin (for example Mexican or Mexican American, Salvadoran, Puerto Rican, Dominican, Cuban, Colombian, etc.) veteran entrepreneurs. NSMAE monitors trends in the activity, needs, and economic, social, and policy barriers of military-affiliated entrepreneurs in the United States.
The Employment Situation Of Veterans: August 2022, Institute For Veterans And Military Families At Syracuse University
The Employment Situation Of Veterans: August 2022, Institute For Veterans And Military Families At Syracuse University
Institute for Veterans and Military Families
Veteran employment trends and statistics among various demographics during August 2022
Twilytics: A Social Perception Analysis Of Public Transit Systems During The Covid-19 Pandemic, Egbe-Etu Etu, Imokhai Tenebe, Ankur Parma, Likhitha Yelamanchili, Dang Minh Nhu Nguyen, Louis Tran, Ihor Markevych
Twilytics: A Social Perception Analysis Of Public Transit Systems During The Covid-19 Pandemic, Egbe-Etu Etu, Imokhai Tenebe, Ankur Parma, Likhitha Yelamanchili, Dang Minh Nhu Nguyen, Louis Tran, Ihor Markevych
Mineta Transportation Institute
In the United States, public transit ridership in 2020 declined by 79% compared to 2019 levels. With lockdowns implemented during the early days of the pandemic, direct human-to-human interactions migrated to virtual platforms (e.g., Facebook, Twitter, and Reddit). Social media platforms have aided researchers in answering numerous questions about current societal dilemmas, including COVID-19. This study investigates the public’s perception of transit systems via a social media analysis given the emergence of vaccines and other COVID-19 preventive measures. Findings revealed themes of fear and confusion concerning the use of public transportation during the pandemic. The public had doubts regarding the …
Routes To Lower Greenhouse Gas Emissions From Freight Transportation In The City Of San José, Serena Alexander, Kyle Laveroni, Maxwell Friedman, Janani Thiagrajan
Routes To Lower Greenhouse Gas Emissions From Freight Transportation In The City Of San José, Serena Alexander, Kyle Laveroni, Maxwell Friedman, Janani Thiagrajan
Mineta Transportation Institute
Freight represents approximately 30% of all transportation-related emissions in the U.S., but local climate action plans (CAPs) and freight plans often place limited emphasis on freight emissions reduction strategies. The objective of this report is to examine and present strategies for the City of San José, California to reduce GHG emissions from freight. The authors conducted a geospatial analysis of freight data related to San José, and an analysis of relevant literature and successful freight reduction strategies implemented globally. The report also provides key objectives and generalized strategies to reduce GHG emissions from freight as well as specific recommendations for …
Vaccine-Linked Chemotherapy With A Low Dose Of Benznidazole Plus A Bivalent Recombinant Protein Vaccine Prevents The Development Of Cardiac Fibrosis Caused By Trypanosoma Cruzi In Chronically-Infected Balb/C Mice, Victor Manuel Dzul-Huchim, Maria Jesus Ramirez-Sierra, Pedro Pablo Martinez-Vega, Miguel Enrique Rosado-Vallado, Victor Ermilo Arana-Argaez, Jaime Ortega-Lopez, Fabian Gusovsky, Eric Dumonteil, Julio Vladimir Cruz-Chan, Peter Hotez, María Elena Bottazzi, Liliana Estefania Villanueva-Lizama
Vaccine-Linked Chemotherapy With A Low Dose Of Benznidazole Plus A Bivalent Recombinant Protein Vaccine Prevents The Development Of Cardiac Fibrosis Caused By Trypanosoma Cruzi In Chronically-Infected Balb/C Mice, Victor Manuel Dzul-Huchim, Maria Jesus Ramirez-Sierra, Pedro Pablo Martinez-Vega, Miguel Enrique Rosado-Vallado, Victor Ermilo Arana-Argaez, Jaime Ortega-Lopez, Fabian Gusovsky, Eric Dumonteil, Julio Vladimir Cruz-Chan, Peter Hotez, María Elena Bottazzi, Liliana Estefania Villanueva-Lizama
Center for Medical Ethics and Health Policy Staff Publications
Background: Chagas disease (CD) is caused by Trypanosoma cruzi and affects 6-7 million people worldwide. Approximately 30% of chronic patients develop chronic chagasic cardiomyopathy (CCC) after decades. Benznidazole (BNZ), one of the first-line chemotherapy used for CD, induces toxicity and fails to halt the progression of CCC in chronic patients. The recombinant parasite-derived antigens, including Tc24, Tc24-C4, TSA-1, and TSA-1-C4 with Toll-like receptor 4 (TLR-4) agonist-adjuvants reduce cardiac parasite burdens, heart inflammation, and fibrosis, leading us to envision their use as immunotherapy together with BNZ. Given genetic immunization (DNA vaccines) encoding Tc24 and TSA-1 induce protective immunity in mice and …
An Ultra-Brief Screening Scale For Pediatric Obsessive-Compulsive Disorder: The Oci-Cv-5, Amitai Abramovitch, Jonathan S Abramowitz, Dean Mckay, Heining Cham, Kennedy S Anderson, Lara J Farrell, Daniel A Geller, Gregory L Hanna, Sharna Mathieu, Joseph F Mcguire, David R Rosenberg, S Evelyn Stewart, Eric A Storch, Sabine Wilhelm
An Ultra-Brief Screening Scale For Pediatric Obsessive-Compulsive Disorder: The Oci-Cv-5, Amitai Abramovitch, Jonathan S Abramowitz, Dean Mckay, Heining Cham, Kennedy S Anderson, Lara J Farrell, Daniel A Geller, Gregory L Hanna, Sharna Mathieu, Joseph F Mcguire, David R Rosenberg, S Evelyn Stewart, Eric A Storch, Sabine Wilhelm
Center for Medical Ethics and Health Policy Staff Publications
Background: Obsessive-compulsive disorder (OCD) is an often disabling and chronic condition that is normally assessed using diagnostic interviews or lengthy self-report questionnaires. This makes routine screening in general health settings impractical, and as a result OCD is often under-(or mis-)recognized. The present study reports on the development of an ultra-brief version of the Obsessive-Compulsive Inventory-Child Version (OCI-CV) which may be administered routinely as a screener for pediatric OCD.
Method: A total of 489 youth diagnosed with OCD, 259 non-clinical controls, and 299 youth with other disorders completed the OCI-CV and other indices of psychopathology. Using item analyses, we extracted five …