Statistics and Probability Commons^™

The Utility Of Bioenergetics Modelling In Quantifying Predation Rates Of Marine Apex Predators: Ecological And Fisheries Implications, A. Barnett, M. Braccini, C. L. Dudgeon, N. L. Payne, K. G. Abrantes, M. Sheaves, E. P. Snelling

Fisheries Research Articles

Predators play a crucial role in the structure and function of ecosystems. However, the magnitude of this role is often unclear, particularly for large marine predators, as predation rates are difficult to measure directly. If relevant biotic and abiotic parameters can be obtained, then bioenergetics modelling offers an alternative approach to estimating predation rates, and can provide new insights into ecological processes. We integrate demographic and ecological data for a marine apex predator, the broadnose sevengill shark Notorynchus cepedianus, with energetics data from the literature, to construct a bioenergetics model to quantify predation rates on key fisheries species in …

Persistent Organic Pollutants And Mortality In The United States, Nhanes 1999-2011., Kristiann Fry, Melinda C Power

Epidemiology Faculty Publications

Background

Persistent organic pollutants (POPs) are environmentally and biologically persistent chemicals that include polybrominated diphenyl ethers (PBDEs), per- and polyfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and organochlorine (OC) pesticides. Currently, data on the associations between exposure to POPs and the risk of mortality in the U.S. population is limited.

Our objective was to determine if higher exposure to POPs is associated with greater risk of all-cause, cancer, heart/cerebrovascular disease, or other-cause mortality.

Methods

Analyses included participants aged 60 years and older from the 1999–2006 National Health and Nutrition Examination Surveys (NHANES). We included 483 participants for analyses of PBDEs, 1043 …

Using Multivariate Statistical Techniques To Aid In A Sports Index Construction, Tiffany Kelly

Mathematics Colloquium Series

Within a quantitative career, you are/will soon be challenged to create an overall value to explain a situational status. For example, socio-economic status, well-being, and in this specific example, happiness among sports fans. This talk seeks to discuss my previous work developed out from student research performed at NSU in its application to my first project for ESPN Sports Analytics, the College Football Fan Happiness Index (http://es.pn/2vmParA) . I will dive into the multivariate statistical techniques of principal component analysis and hierarchal clustering to create this happiness index from a slew of variables.

A Bivariate Hypothesis Testing Approach For Mapping The Trait-Influential Gene, Garrett Saunders, Matthew D. Meng, John R. Stevens

Mathematics and Statistics Faculty Publications

The linkage disequilibrium (LD) based quantitative trait loci (QTL) model involves two indispensable hypothesis tests: the test of whether or not a QTL exists, and the test of the LD strength between the QTaL and the observed marker. The advantage of this two-test framework is to test whether there is an influential QTL around the observed marker instead of just having a QTL by random chance. There exist unsolved, open statistical questions about the inaccurate asymptotic distributions of the test statistics. We propose a bivariate null kernel (BNK) hypothesis testing method, which characterizes the joint distribution of the two test …

Latent Storm Factors And Their Indicators, Joy D'Andrea

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Open Source Artificial Intelligence In A Biological/Ecological Context, Trevor Grant

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Deep Learning In R, Troy Hernandez

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Discrete Stochastic Modeling For First-Year Biology Students, Dmitry Kondrashov

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Handguns And Hotspots: Spatio- Temporal Models For Gun Violence In Chicago,Il, Shelby Scott

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

A Simulation Of Anthropogenic Columbian Mammoth Extinction, Alex Capaldi

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Investigating Statistics Teachers' Knowledge Of Probability In The Context Of Hypothesis Testing, Jason Mark Asis Dolor

Dissertations and Theses

In the last three decades, there has been a significant growth in the number of undergraduate students taking introductory statistics. As a result, there is a need by universities and community colleges to find well-qualified instructors and graduate teaching assistants to teach the growing number of statistics courses. Unfortunately, research has shown that even teachers of introductory statistics struggle with concepts they are employed to teach. The data presented in this research sheds light on the statistical knowledge of graduate teaching assistants (GTAs) and community college instructors (CCIs) in the realm of probability by analyzing their work on surveys and …

Quantifying Certainty: The P-Value, Dominic Klyve

Statistics and Probability

No abstract provided.

Data Envelopment Analysis Using Glpkapi In R, Konrad Miziolek, Jordan Beary, Shreyas Vasanth, Surekha Chanamolu, Rudraxi Mitra

Engineering and Technology Management Student Projects

The work done here is primarily a wrapper function written to separate some of the more difficult-to-use glpkAPI functionality from the end-user. The user, when prompted, selects the appropriate configuration of the .mod file to the task (for example, output-oriented CRS), and the data file, as a .dat. The function then loads the required glpkAPI library, and carries forward the model. It allocates the problem and workspace, reads the model file and data file the user selects, builds the problem, and solves it. The function returns primal values, and, if dual = TRUE is selected, also returns dual weights.

Spatiotemporal Subspace Feature Tracking By Mining Discriminatory Characteristics, Richard D. Appiah

Doctoral Dissertations

Recent advancements in data collection technologies have made it possible to collect heterogeneous data at complex levels of abstraction, and at an alarming pace and volume. Data mining, and most recently data science seek to discover hidden patterns and insights from these data by employing a variety of knowledge discovery techniques. At the core of these techniques is the selection and use of features, variables or properties upon which the data were acquired to facilitate effective data modeling. Selecting relevant features in data modeling is critical to ensure an overall model accuracy and optimal predictive performance of future effects. The …

On Congruence Lattices Of Nilsemigroups, Alexander L. Popovich, Peter R. Jones

Mathematics, Statistics and Computer Science Faculty Research and Publications

We prove that the congruence lattice of a nilsemigroup is modular if and only if the width of the semigroup, as a poset, is at most two, and distributive if and only if its width is one. In the latter case, such semigroups therefore coincide with the nil Δ">Δ Δ -semigroups. It is further shown that if a finitely generated nilsemigroup has modular congruence lattice, then the semigroup is finite.

The Double-Edged Sword: A Mixed Methods Study Of The Interplay Between Bipolar Disorder And Technology Use, Mark Matthews, Elizabeth Murnane, Jaime Snyder, Shion Guha, Pamara Chang, Gavin Doherty, Geri K. Gay

Mathematics, Statistics and Computer Science Faculty Research and Publications

Human behavior is increasingly reflected or acted out through technology. This is of particular salience when it comes to changes in behavior associated with serious mental illnesses including schizophrenia and bipolar disorder. Early detection is crucial for these conditions but presently very challenging to achieve. Potentially, characteristics of these conditions' traits and symptoms, at both idiosyncratic and collective levels, may be detectable through technology use patterns. In bipolar disorder specifically, initial evidence associates changes in mood with changes in technology-mediated communication patterns. However much less is known about how people with bipolar disorder use technology more generally in their lives, …

Emergency Diesel-Electric Generator Set Maintenance And Test Periodicity, Stephen John Fehr

Engineering Management & Systems Engineering Theses & Dissertations

Manufacturer and industry recommendations vary considerably for maintenance and tests of emergency diesel-electric generator sets in emergency standby duty. There is little consistency among generator sets of similar technology, and manufacturers and their representatives often provide contradictory guidance. As a result, periodicity of emergency diesel-electric generator set maintenance and tests varies considerably in practice. Utilizing the framework proposed and tested by Fehr (2014), this research developed a parametric regression survival model of the reliability of modern diesel-electric generator sets in emergency standby duty as a function of maintenance, age, and cumulative run hours. A survival regression technique leveraging Cox’s (1972) …

Increased Birth Weight Is Associated With Altered Gene Expression In Neonatal Foreskin, Leryn J. Reynolds, Rebecca I. Pollack, Richard J. Charnigo, Cetewayo S. Rashid, Arnold J. Stromberg, Shu Shen, John O'Brien, Kevin J. Pearson

Pharmacology and Nutritional Sciences Faculty Publications

Elevated birth weight is linked to glucose intolerance and obesity health-related complications later in life. No studies have examined if infant birth weight is associated with gene expression markers of obesity and inflammation in a tissue that comes directly from the infant following birth. We evaluated the association between birth weight and gene expression on fetal programming of obesity. Foreskin samples were collected following circumcision, and gene expression analyzed comparing the 15% greatest birth weight infants (n = 7) v. the remainder of the cohort (n = 40). Multivariate linear regression models were fit to relate expression levels on differentially …

Rates And Causes Of Accidents For General Aviation Aircraft Operating In A Mountainous And High Elevation Terrain Environment, Marisa Aguiar, Alan Stolzer, Douglas D. Boyd

Publications

Flying over mountainous and/or high elevation terrain is challenging due to rapidly changeable visibility, gusty/rotor winds and downdrafts and the necessity of terrain avoidance. Herein, general aviation accident rates and mishap cause/factors were determined (2001–2014) for a geographical region characterized by such terrain.

Accidents in single piston engine-powered aircraft for states west of the US continental divide characterized by mountainous terrain and/or high elevation (MEHET) were identified from the NTSB database. MEHET-related-mishaps were defined as satisfying any one, or more, criteria (controlled flight into terrain/obstacles (CFIT), downdrafts, mountain obscuration, wind-shear, gusting winds, whiteout, instrument meteorological conditions; density altitude, dust-devil) cited …

Systems Biology Approach To Late-Onset Alzheimer's Disease Genome-Wide Association Study Identifies Novel Candidate Genes Validated Using Brain Expression Data And Caenorhabditis Elegans Experiments, Shubhabrata Mukherjee, Joshua C. Russell, Daniel T. Carr, Jeremy D. Burgess, Mariet Allen, Daniel J. Serie, Kevin L. Boehme, John S. K. Kauwe, Adam C. Naj, David W. Fardo, Dennis W. Dickson, Thomas J. Montine, Nilufer Ertekin-Taner, Matt R. Kaeberlein, Paul K. Crane

Biostatistics Faculty Publications

Introduction—We sought to determine whether a systems biology approach may identify novel late-onset Alzheimer's disease (LOAD) loci.

Methods—We performed gene-wide association analyses and integrated results with human protein-protein interaction data using network analyses. We performed functional validation on novel genes using a transgenic Caenorhabditis elegans Aβ proteotoxicity model and evaluated novel genes using brain expression data from people with LOAD and other neurodegenerative conditions.

Results—We identified 13 novel candidate LOAD genes outside chromosome 19. Of those, RNA interference knockdowns of the C. elegans orthologs of UBC, NDUFS3, EGR1, and ATP5H were associated with Aβ …

Healthcare Outcomes And Resource Utilization Associated With Neonatal Hypoglycemia: Analysis Of Data From The Hcup Kid’S Inpatient Database, Brook T. Alemu

Health Services Research Dissertations

Neonatal hypoglycemia is the most common metabolic abnormality in infants and is associated with neurological damage and death. The risk of developing hypoglycemia among infants born from diabetic mothers is even higher. Although much work has been performed addressing issues for treatment and care, research related to neonatal hypoglycemia has been focused on the clinical or individual level risk factors. Contextual risk factors such as hospital characteristics, neighborhood economic status, and regional variations were not considered in earlier studies. Additionally, although healthcare resources utilization of hypoglycemia has been adequately addressed in the adult population, this topic has not been studied …

Estimation Of A Noisy Subordinated Brownian Motion Via Two-Scales Power Variations, José E. Figueroa-López, Kiseop Lee

Mathematics Faculty Research

High frequency based estimation methods for a semiparametric pure-jump subordinated Brownian motion exposed to a small additive microstructure noise are developed building on the two-scales realized variations approach originally developed by Zhang et al. (2005) for the estimation of the integrated variance of a continuous Itô process. The proposed estimators are shown to be robust against the noise and, surprisingly, to attain better rates of convergence than their precursors, method of moment estimators, even in the absence of microstructure noise. Our main results give approximate optimal values for the number K of regular sparse subsamples to be used, which is …

Methods For Analyzing Attribute-Level Best-Worst Discrete Choice Experiments, Amanda Faye Working

Mathematics & Statistics Theses & Dissertations

Discrete choice experiments (DCEs) have applications in many areas such as social sciences, economics, transportation research, health systems, and clinical decisions to mention a few. Usually discrete choice models (DCMs) focus on predicting the product choice; however, these models do not provide information about what attributes of the products are impacting consumers’ choices the most. Today, it is common to record the best and worst features of a product (or profile), also called attribute levels, and the goal is to investigate and build models for estimation of attribute and attribute-level impacts on consumer behavior. Attribute-level best-worst DCEs provide information into …

Statistical Analysis And Modeling Of Ovarian And Breast Cancer, Muditha V. Devamitta Perera

USF Tampa Graduate Theses and Dissertations

The objective of the present study is to investigate key aspects of ovarian and breast cancers, which are two main causes of mortality among women. Identification of the true behavior of survivorship and influential risk factors is essential in designing treatment protocols, increasing disease awareness and preventing possible causes of disease. There is a commonly held belief that African Americans have a higher risk of cancer mortality. We studied racial disparities of women diagnosed with ovarian cancer on overall and disease-free survival and found out that there is no significant difference in the survival experience among the three races: Whites, …

Investigating The Student Enrollment Decision At Wku, Alec Brown

Mahurin Honors College Capstone Experience/Thesis Projects

The purpose of this research is to investigate the relationships between the enrollment decision of first-time, first-year students admitted to Western Kentucky University and the amount of financial aid awarded, as well as demographic information. The Division of Enrollment Management provided a SAS dataset containing various information about all WKU students admitted in 2013, 2014, and 2015. Additionally, information about the 2016 class of admitted students was provided. The data has been analyzed in SAS Enterprise Miner. We performed analysis using decision tree modeling and logistic regression modeling. Results of these two procedures indicated the importance of credit hours earned …

Comparison Of Adaptive Randomized Trial Designs For Time-To-Event Outcomes That Expand Versus Restrict Enrollment Criteria, To Test Non-Inferiority, Josh Betz, Jon Arni Steingrimsson, Tianchen Qian, Michael Rosenblum

Johns Hopkins University, Dept. of Biostatistics Working Papers

Adaptive enrichment designs involve preplanned rules for modifying patient enrollment criteria based on data accrued in an ongoing trial. These designs may be useful when it is suspected that a subpopulation, e.g., defined by a biomarker or risk score measured at baseline, may benefit more from treatment than the complementary subpopulation. We compare two types of such designs, for the case of two subpopulations that partition the overall population. The first type starts by enrolling the subpopulation where it is suspected the new treatment is most likely to work, and then may expand inclusion criteria if there is early evidence …

Judging The Neonatal Abstinence Syndrome Assessment Tools To Guide Future Tool Development: The Use Of Clinimetrics As Opposed To Psychometrics, Philip M. Westgate, Enrique Gomez-Pomar

Biostatistics Faculty Publications

In the face of the current Neonatal Abstinence Syndrome (NAS) epidemic, there is considerable variability in the assessment and management of infants with NAS. In this manuscript, we particularly focus on NAS assessment, with special attention given to the popular Finnegan Neonatal Abstinence Score (FNAS). A major instigator of the problem of variable practices is that multiple modified versions of the FNAS exist and continue to be proposed, including shortened versions. Furthermore, the validity of such assessment tools has been questioned, and as a result, the need for better tools has been suggested. The ultimate purpose of this manuscript, therefore, …

Dietary Inflammatory Index And Colorectal Cancer Risk – A Meta-Analysis, Nitin Shivappa, Justyna Godos, James R. Hébert, Michael David Wirth, Gabriele Piuri, Attilio Speciani, Giuseppe Grosso

Faculty Publications

Diet and chronic inflammation of the colon have been suggested to be risk factors in the development of colorectal cancer (CRC). The possible link between inflammatory potential of diet, measured through the Dietary Inflammatory Index (DII®), and CRC has been investigated in several populations across the world. The aim of this study was to conduct a meta-analysis on studies exploring this association. Data from nine studies were eligible, of which five were case-control and four were cohort studies. Results from meta-analysis showed a positive association between increasing DII scores, indicating a pro-inflammatory diet, and CRC. Individuals in the highest versus …

Prevention Of Renal Apob Retention Is Protective Against Diabetic Nephropathy: Role Of Tgf-Β Inhibition, Patricia G. Wilson, Joel C. Thompson, Meghan S. Yoder, Richard Charnigo, Lisa R. Tannock

Internal Medicine Faculty Publications

Animal studies demonstrate that hyperlipidemia and renal lipid accumulation contribute to the pathogenesis of diabetic nephropathy (DN). We previously demonstrated that renal lipoproteins colocalize with biglycan, a renal proteoglycan. The purpose of this study was to determine whether prevention of renal lipid (apoB) accumulation attenuates DN. Biglycan-deficient and biglycan wild-type Ldlr^−/− mice were made diabetic via streptozotocin and fed a high cholesterol diet. As biglycan deficiency is associated with elevated transforming growth factor-β (TGF-β), in some experiments mice were injected with either the TGF-β-neutralizing antibody, 1D11, or with 13C4, an irrelevant control antibody. Biglycan deficiency had no significant effect …

Randomized Trial Of Interventions To Improve Childhood Asthma In Homes With Wood-Burning Stoves, Curtis W. Noonan, Erin O. Semmens, Paul Smith, Solomon W. Harrar, Luke Montrose, Emily Weiler, Marcy Mcnamara, Tony J. Ward

Statistics Faculty Publications

BACKGROUND: Household air pollution due to biomass combustion for residential heating adversely affects vulnerable populations. Randomized controlled trials to improve indoor air quality in homes of children with asthma are limited, and no such studies have been conducted in homes using wood for heating.

OBJECTIVES: Our aims were to test the hypothesis that household-level interventions, specifically improved-technology wood-burning appliances or air-filtration devices, would improve health measures, in particular Pediatric Asthma Quality of Life Questionnaire (PAQLQ) scores, relative to placebo, among children living with asthma in homes with wood-burning stoves.

METHODS: A three-arm placebo-controlled randomized trial was conducted in homes with …