Chemistry Commons^™

California - Peralta Weigh Station, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication (2001)

Environmental Science & Technology Publication (2012)

Environmental Science & Technology Publication (2013)

Environmental Science & Technology Publication (2018)

Air & Waste Management Journal (2021)

2008 Final Report

2009 Final Report

2010 Final Report

2012 Final Report

2017 Final Report

Texas - San Marcos Weigh Station 1998, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication

Final Report

Novel Detection Methods And Gas-Free Hydroxide Eluent Generator For Capillary Liquid/Ion Chromatography, Bikash Chouhan

Chemistry & Biochemistry Dissertations - Archive

The light absorbed by a molecule, except for an efficient fluorophore, is mostly converted into heat, thereby causing a change in temperature. In a liquid flow system, this change in temperature results in changes in the refractive index (RI) and electrical conductivities of the solution. Photothermal measurement of optical absorption (PMOA) most often involves detecting the temperature change indirectly by measuring changes in pressure, RI, or conductivity. In a small-bore capillary, the PMOA detection technique has some distinct advantages: (a) no penalty is paid for smaller path length, (b) there are no stray light issues, and (c) a broadband light …

New Strategies For Hydrosilylation Of Propargyl Alcohols, Olefin Polymerization And On-Chip Organic Synthesis, Udaya Sree Dakarapu

Chemistry & Biochemistry Dissertations - Archive

The research described in this dissertation is on three different projects namely i) design and synthesis of traceless hydrosilyl acetal-directed, exo-syn hydrosilylation of propargyl alcohols to produce α-hydroxy (E)-vinylsilanes, ii) alkali metal lewis base-catalyzed, complexation-induced hydrogen atom transfer (LBCI-HAT) olefin polymerization and iii) on-chip organic synthesis enabled by engine-and-cargo on an electrowetting-on-dielectric digital microfluidic (EWOD) device. The first chapter is focused on the design and synthesis of traceless hydrosilyl acetal-directed, exo-syn hydrosilylation of propargyl alcohols to produce α-hydroxy (E)-vinylsilanes. Transition metal-catalyzed regioselective intramolecular hydrosilylation of propargylic alcohols utilizing easily accessible, inexpensive, and readily installable hydrosilyl acetals as a directing group …

Synthesis, Study, And Applications Of Highly Fluorinated Copper Pyrazolate Complexes Of Small Alkene, Alkynes And Carbon Monoxide, Devaborniny Parasar

Chemistry & Biochemistry Dissertations - Archive

Trinuclear copper pyrazolate complexes (copper trimers) function as excellent precursors to synthesize multinuclear complexes of copper. Using highly fluorinated pyrazolates as supporting ligands, we have successfully synthesized and isolated several unique complexes of copper with alkene (e.g., ethylene), alkynes (e.g., 3-hexyne, butyne, acetylene, etc.) and carbon monoxide from the copper trimers. Synthetic details, solid-state structures, and physico-chemical properties of a series of multinuclear complexes have been studied. Chapter 2 of this research work focuses on the olefin/paraffin separation technology. For this we have succesfully synthesized a novel, highly fluorinated copper pyrazolate complex, that undergoes remarkable structural rearrangement forming a dinuclear …

Computational Elucidation Of The "Coloring Problem" In Rhenium Aluminum Silicon Compounds, Alec George Neeson

Graduate Theses/Dissertations

Re₁Si₁Al₁ and its related compounds are potential thermoelectric materials. Previously, it was reported to adopt a MoSi₂-type structure with Si and Al atoms statistically sharing the same crystallographic sites. This recent study indicates otherwise – Si and Al are segregated and occupy different sites when mixed with a 1:1:1 stoichiometry. To confirm and rationalize the segregation between Si and Al, this research studied this compound with first-principle calculations. Several model structures have been constructed for Re₁Si₁Al₁ including a number of different super-cell models. Energy analysis confirmed that the …

Toward Development Of A Paper-Based Microanalytical Device For Heavy Metal Ion Detection By Enzyme Inhibition, Adjoa Otubea Adams

Graduate Theses/Dissertations

In recent years, paper-based microanalytical devices have attracted great attention in broad application areas including the colorimetric detection of heavy metal ions. The simplicity, portability, and low cost of the devices offer unique advantages over conventional instrumental analysis. This project utilizes the inhibition of an enzyme-catalyzed reaction by metal ions to develop a paper-based analytical device for the detection of heavy metal contaminants such as mercury. I selected alkaline phosphatase for this study. This enzyme possesses Mg and Zn ions in its active site. Therefore, the competitive displacement of these metal ions and/or denaturation of the enzyme by heavy metal …

In Silico Investigation For The Conversion Of Methyl Oleate To Gasoline, Arkanil Roy

Graduate Theses/Dissertations

Petroleum products are found in all walks of life. From the plastic casing on a cell phone to the gasoline that runs most vehicles, a lot is derived from petroleum. Ubiquitous use of petroleum has adversely affected the environment. Toxic substances such as SOx and NOx are released into the atmosphere during the processing and usage of petroleum products, which contributes to global warming. Inevitable oil spills cause devastating effects to marine ecosystems. The rate of regeneration of petroleum is much slower than the rate of usage that would lead to it being exhausted in the recent future. Hence, a …

Investigating Chitosan Modified With Triethylammonium Butanamide And Triethylphosphonium Butanamide As Non-Viral Gene Delivery Vectors By Examining Cytotoxicity And Transfection Efficiency, Deborah C. Ehie

Graduate Theses/Dissertations

Gene therapy is a very challenging field, especially with new emerging genetic disorders. Chitosan (CS), due to chitosan’s flexibility, biocompatibility, and biodegradability, has been of interest in the world of gene therapy especially as researchers are gravitating towards non-viral vectors due to the problems caused by viral vectors. Nevertheless, there are still issues regarding solubility, cellular uptake of cargos being transported in vitro or in vivo, increased cytotoxicity levels, as well as many other things that prevent chitosan from being an efficient gene delivery agent. Here I present five derivatives of chitosan, which were all modified with either triethylphosphonium …

Designing A Reactor Chamber For Hot Electron Chemistry On Bimetallic Plasmonic Nanoparticles, Bryn Merrill, Bingjie Zhang, Jerry Larue

SURF Posters and Papers

Catalysis provides pathways for efficient and selective chemical reactions by lowering the energy barriers for desired products. Gold nanoparticles (AuNPs) show excellent promise as plasmonic catalysts. Plasmonic materials have localized surface plasmon resonances, oscillations of the electron bath at the surface of a nanoparticle, that generate energetically intense electric fields which rapidly decay into energetically excited electrons. The excited electrons have the potential to destabilize atoms strongly bound to the catalysts through occupation of antibonding orbitals. Tuning the antibonding orbitals to make them accessible for occupancy by electrons is achieved by coating the AuNP in a thin layer of another …

Investigation Of Computational Determination Of Elastic Properties For Silicon Nitride And Silicon Carbonitride Materials, Timothy Aaron West

Chemistry & Biochemistry Theses - Archive

Silicon nitride and silicon carbonitride materials are versatile materials exhibiting useful properties at high temperatures and pressures. This study investigates the use of molecular dynamics simulations to determine the elastic properties of these materials. Elastic constants and moduli are determined for a series of crystalline and amorphous silicon nitride materials and amorphous silicon carbonitride materials employing Tersoff, Garofalini, and Marian-Gastreich two-body empirical potentials. Our results show that the Tersoff empirical potential is best suited of the three under study to elastic property determination. Results also show that the elastic behavior of silicon carbonitride is highly dependent on the morphology of …

California - Port Of Los Angeles, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication (2012)

Environmental Science & Technology Publication (2013)

2008 Final Report

2009 Final Report

2010 Final Report

2012 Final Report

Colorado - Dumont Weigh Station, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication (2001)

Environmental Science & Technology Publication (2006)

Thesis

Switzerland - Canton Of Uri 1998, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication

Texas - Port Of Houston 2009, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Thesis

Colorado - Coors Brewery, University Of Denver

FEAT Heavy-Duty Vehicle Measurements

Relevant Publications

Environmental Science & Technology Publication (2001)

Environmental Science & Technology Publication (2006)

Thesis

Probing The Surface Acidity Of Supported Aluminum Bromide Catalysts, Md Ashraful Abedin, Swarom Kanitkar, Nitin Kumar, Zi Wang, Kunlun Ding, Graham Hutchings, James J. Spivey

Faculty Publications

Solid acid catalysis is an important class of reactions. The principal advantages of solid acid catalysts as compared to their corresponding fluid acids include minimal waste and ease of product separation. One type of these catalysts is based on aluminum bromide (Al2Br6), which is a stronger Lewis acid than Al2Cl6. In this report, Al(2)Br(6)is grafted on commercial mesoporous silica (CMS), SBA-15 and silica gel to create a solid catalyst similar to the silica-supported Al(2)Cl(6)superacid. These supported Al(2)Br(6)catalysts were characterized by NH3-Temperature Programmed Desorption (TPD), pyridine Diffuse Reflectance for Infrared Fourier Transform Spectroscopy (DRIFTS) and Magic Angle Spinning Nuclear Magnetic Resonance …

Nanoceria Distribution And Effects Are Mouse-Strain Dependent, Robert A. Yokel, Michael T. Tseng, D. Allan Butterfield, Matthew L. Hancock, Eric A. Grulke, Jason M. Unrine, Arnold J. Stromberg, Alan K. Dozier, Uschi M. Graham

Pharmaceutical Sciences Faculty Publications

Prior studies showed nanoparticle clearance was different in C57BL/6 versus BALB/c mice, strains prone to Th1 and Th2 immune responses, respectively. Objective: Assess nanoceria (cerium oxide, CeO₂ nanoparticle) uptake time course and organ distribution, cellular and oxidative stress, and bioprocessing as a function of mouse strain. Methods: C57BL/6 and BALB/c female mice were i.p. injected with 10 mg/kg nanoceria or vehicle and terminated 0.5 to 24 h later. Organs were collected for cerium analysis; light and electron microscopy with elemental mapping; and protein carbonyl, IL-1β, and caspase-1 determination. Results: Peripheral organ cerium significantly increased, generally more …

Determining The Relative Activities Of Wild-Type Mycobacterium Tuberculosis Indole-3-Glycerol Phosphate Synthase And Mutants E57a And E219a With An Investigation Into The Relationship Between Wild-Type Mycobacterium Tuberculosis Igps Activity And Ph, Thomas Emmanuel Candela

Theses, Dissertations and Culminating Projects

The relationship between wild-type protein indole-3-glycerol phosphate synthase (IGPS) activity and pH was investigated through the formation of pH activity profiles, and the relative catalytic activities of wild-type Mycobacterium tuberculosis and mutants E57A and E219A were also deduced in this work. The activity of each enzyme variant was determined by reacting native substrate 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate with enzyme buffered at pH 7.5 in a cuvette and using a fluorometer to detect the increase in fluorescent signal produced by the formation of fluorescent product indole-3 glycerol phosphate. Work with wild-type IGPS showed the enzyme to have a kcat of 1.26 ± 1.75 (s …

Characterizing Functions Of Two Regulatory Proteins In The Parasitic Nematode Brugia Malayi And Their Potential As Drug Targets In Treating Lymphatic Filariasis, Brittany Amber Hart

Theses, Dissertations and Culminating Projects

Lymphatic filariasis (LF) is a debilitating disease caused by parasitic nematodes that affect millions of people in largely tropical environments. While drugs are available for treating LF, they suffer from a lack of efficacy against adult parasites, toxicity, and emergence of resistance. Here, we describe two novel potential drug targets within the filarial parasite, Brugia malayi (B. malayi). These two proteins, bm9350, a predictive MAPK stress response protein, and bm2032, a potential histone modifying enzyme, have little or no annotation or experimental evidence of function. Using predictive analysis and tools, we examined potential functions of these proteins and their potential …

Studies Toward The Synthesis Of A Novel Diamine Scaffold, Joseph Edward Quinlan Iii

Theses, Dissertations and Culminating Projects

The orexin system in humans contains receptors Orexin 1 (OX1) and Orexin 2 (OX2). These receptors are involved in numerous physiological processes including wake/sleep cycling, energy homeostasis, and motivation/reward. In scientific literature, it is known that antagonism of these receptors exhibits therapeutic effects in the realm of cocaine and alcohol addiction, as well as sleep disorders. On the market today exist drugs for treatment of sleep disorders through orexin receptor antagonization. Here we report a synthesis toward novel conformationally rigid antagonists of the orexin receptor system that may provide improved affinity and/or selectivity compared to known compounds. We report the …

Strategies For Enhancing Chromatographic Efficiencies In Chiral And Achiral Supercritical And Liquid Chromatography, Daipayan Roy

Chemistry & Biochemistry Dissertations - Archive

The fundamental aim of chromatography has been to achieve baseline separation between the components of a mixture in the shortest possible time. Recently there has been a shift in the chromatographic focus of enantiomeric separations, with an emphasis on increasing the efficiency of columns. Superficially porous particles (SPP) introduced about a decade ago lead to a surge in efficiency as compared to the traditionally used fully porous particles (FPP). Recently chiral selectors bonded to superficially porous particles have been commercialized. This work reports new methods for enantioseparation using chiral selectors like macrocyclic glycopeptides, modified cyclodextrins and cyclofructans bonded to SPPs. …

Water Cluster Motifs In Structurally Similar N-(2-Aminoethyl)-1-Methylimidazole-2-Carboxamide Metal Complexes: Synthesis, Characterization, Thermal And Electrical Properties., Nina Saraei

Electronic Theses and Dissertations

Water is a remarkable molecule and in all of its forms exhibits an amazing collection of properties and functions. Besides its crucial role in life and many technological processes, water displays some unusual and anomalous properties at various interfaces and under different conditions. Although the role of hydrogen-bonding interactions and their fluctuations are well known to determine the properties of water, the main obstacle exists in the complexity of correctly describing the interactions between water molecules. The key to understanding the behavior of water is to collect precise structural data of various H-bonded water networks in diverse environments. In this …

(Pseudo)Phase Tuning In The Service Of Synthesis: Technologies For Sustainable Catalysis., Justin Douglas Smith

Electronic Theses and Dissertations

Strategies for manipulation of chemical phases were explored with emphasis on synthetic chemistry applications. Some strategies are fairly divergent from their origin, but all ultimately began from investigations of micellar media. Accordingly, Chapter 1 reviews the historical development of micellar catalytic processes. Chapters 2 and 3 detail development of synthetic methods in micellar solutions of designer surfactant PS-750-M. PS-750-M was designed to create benign micellar solutions which effectively mimic toxic organic solvents; it contains a proline-based linker between its hydrophobic and hydrophilic regions which imparts increased polarity to the micellar core. Chapter 2 details an interfacial nucleophilic substitution of perfluoroarenes …

The Legacy Of Mining In Southwest Missouri: Past And Present Conditions Of The Tri-State Mining District, Anastasia M C Mcclanahan

Graduate Theses/Dissertations

The historic Tri-State Mining District (TSMD) of southwestern Missouri, southeastern Kansas, and northeastern Oklahoma has a history of lead and zinc mining that extended over a hundred years. During the district’s peak production period, the TSMD was one of the world’s largest producers of lead and zinc. The mining activities in the TSMD produced economic growth that supported the local communities and were essential to the victory of the Allied Forces during World War I and World War II. Beginning in the 1920s, the mining activities in the district slowly began to cease due to depletion of metal ores and …

Assessing The Robustness And Versatility Of Nanojars For Anion Binding, Mia Lily Ann Jawor

Masters Theses

Supramolecular chemistry is a field in chemistry that focuses on intermolecular bonds in a “host-guest complex” or supramolecular assemblies. Nanojars are supramolecular assemblies of the formula [anion⊂{Cu(μ-OH)(μ-pz)}_n] (n = 27‒33) which incarcerate kosmotropic anions, such as carbonate (CO₃^2‒), sulfate (SO₄^2‒) and hydrogen phosphate (HPO₄^2‒). Nanojars consist of three [Cu(μ-OH)(μ-pz)]_x (x = 6‒14, except 11) rings that are assembled similarly to Matryoshka dolls, where the top and bottom rings act as guests for the central ring. The larger central ring is bound to the two smaller rings by multiple …

Embedded Gold Nanoparticles For Metal Enhanced Photoluminescence, Hasna Alali

Dissertations

Noble metal nanoparticles (MNPs) have attracted great attention in electronics, solar cells and catalysis. Their unique optical properties and biocompatibility makes them useful in biological applications like imaging, drug delivery, therapy and diagnostic. At the surface of MNPs the collective oscillation of free electrons resonates with a particular wavelength of incident light, generating the Localized Surface Plasmons Resonance (LSPR). LSPR results in absorption and scattering of incident light. Scattering results in reflecting photons and absorption leads to enhanced photoluminescence and quenching of fluorophores, if the fluorophore is in the vicinity of MNPs.

Most of the studies in this regard have …

Structural Characterization Of Organic Matter In Oil Shales Using Multiple Nuclear Magnetic Resonance Spectroscopic Techniques, Wenying Chu

Chemistry & Biochemistry Theses & Dissertations

Oil shale is a promising source of hydrocarbon fuel that is distributed throughout the world. The petroleum generating potential of oil shale is related to the molecular structure of the organic matter in source rock. The major fraction of organic matter of oil shale is termed kerogen, and due to its insolubility in organic solvents, ¹³C solid-state nuclear magnetic resonance (NMR) spectroscopy is one of the best ways to directly measure the insoluble organic matter without changing its chemical structures. This dissertation investigated oil shale samples using advanced solid-state ¹³C NMR spectroscopy techniques and high resolution magic angle …

Innovative Approaches In The Discovery Of Aquatic Mycobacteriophages, Janis H. Doss

Biomedical Sciences Theses & Dissertations

Bacteriophages (phages), viruses that infect bacteria, have many applications in medicine, agriculture, molecular biology, and other fields. As antibiotic resistance becomes an increasing problem, interest in phages has grown. The traditional techniques of phage discovery are successful for some phages, but others require modified procedures to achieve detectable host infection.

Mycobacterium is a diverse bacterial genus characterized by a unique cell wall containing mycolic acids, which aids in survival and pathogenesis. The aims of the present research were to isolate mycobacteriophages, use bioinformatics techniques to analyze mycobacterial prophages, and combine genetic analysis with multi-well plate host range studies to identify …

Application Of Carbon Nanoparticles As Dna Detection Probe And Fluorescent Ink, Luckio Frank Owuocha

Graduate Theses/Dissertations

There is a significant interest in developing a sensitive, selective, efficient, and inexpensive method for rapid molecular diagnostic tests. This research aims to develop an inexpensive nucleic acid detection method by using DNA-conjugated carbon nanoparticles that exhibit fluorescence in the visible region. Carbon nanoparticles of this class can be detected without specialized equipment and have great promise toward the development of analytical methods that can be used in resource-limited environments with a lack of access to proper diagnostic and healthcare. We employed EDC-NHS (two-step) and EDC (one-step) coupling techniques to prepare DNA-conjugated carbon nanoparticles. The dot blotting method was adapted …