Chemistry Commons^™

Rhodium On Alumina Catalyzed Hydrodechlorination Of Trichlorethylene, Amber Krueger, Gage Mueller

Celebrating Scholarship and Creativity Day (2018-)

Chlorinated ethylenes are common groundwater contaminants that persist in the environment and pose significant risks to human health such as damage to the nervous system, liver, kidneys, and even increased risk of cancer. Catalytic dehydrochlorination has emerged as a promising strategy for detoxifying compounds such as trichloroethylene (TCE). This study investigates whether rhodium on alumina (Rh/Al₂O₃) in the presence of hydrogen gas can completely degrade TCE to non-toxic products without the accumulation of harmful chlorinated intermediates. While palladium catalysts have been widely studied for dehydrochlorination, the activity and mechanism of rhodium supported on alumina in aqueous systems remains less characterized. …

Supercritical Fluid Extractions Of Organic Compounds For Chemistry 202 Laboratory, Avery Polipnick, Autumn Larson

Celebrating Scholarship and Creativity Day (2018-)

Supercritical fluid extractions are a green chemistry technique that is used to isolate nonpolar compounds, without the use of solvents that are harmful to the environment. Compounds reach their supercritical point which is found above their critical temperature and pressure causing them to be in a state between liquid and gas phases. Carbon dioxide in its supercritical fluid form acts as a solvent. This study investigates how a supercritical carbon dioxide extraction can be incorporated into the Chemistry 202 Laboratory curriculum at the College of Saint Benedict and Saint John’s University. Initial conditions for this extraction were previously determined. The …

Creating A Unique Hemoglobin-Based Oxygen Carrier, Clayton Fuller

Celebrating Scholarship and Creativity Day (2018-)

The purpose of this thesis is to explain the current state of alternative oxygen carriers and propose a new hemoglobin-based oxygen carrier (HBOC) as a blood substitute/ blood therapeutic. Blood donation has drawbacks: risk of spread of infection, short storage time, and blood typing, and the current shortage. There are several possible modifications for hemoglobin to create a carrier (HBOC) which address specific issues related to allowing free hemoglobin to exist extra cellularly. One issue to address is vasoconstriction caused by nitric oxide scavenging, which has been solved by increasing the molecular weight of the HBOC via (co)polymerization, or by …

Form And Fusion: The Art And Science Of Ceramics And Glass, Juniper J. Bauroth-Sherman, Kaleigh Evans

Interdivisional Studies Presentations

The first Ceramics & Art class (IDS-110-F: ST: Ceramics) has completed an immersive, interdisciplinary exploration of stained glass and we’re excited to showcase it now. Through hands-on studio work, experiments, and design projects, we combined artistic expression with the science of glass—learning how physics and chemistry shape everything from color to strength and light interaction. The students have developed practical skills in cutting, grinding, foiling, soldering, and assembling stained-glass pieces, while also experimenting with thermal stress, light transmission, and color chemistry. Glass is now understood as not just as an art form, but as a dynamic material grounded in scientific …

Folic Acid–Carbon Dot–Gemcitabine Nanoparticles For Targeted Cancer Drug Delivery, Irfan Huda, Hua Mei

SPARK Symposium Presentations

This project aims to develop a folic acid-attached carbon dot nanoparticle system (FA-CDs-GEM) for the targeted delivery of gemcitabine to cancer cells. While gemcitabine is widely used, its effectiveness is limited because a short in vivo half life and lack of selectivity, which lead to severe side effects. Carbon dots offer a simple and modifiable platform as the drug delivery and bioimaging agent. Conjugation of folic acid to the carbon dots enables selective targeting of cancer cells that overexpress folate receptors. In this study, we synthesized and characterized FA-CD-GEM nanoparticles and developed an HPLC calibration curve of GEM to accurately …

Developing A Course-Based Undergraduate Research Experience For Chem 122, Melanie J. Harvey Phd

Sabbatical Projects

Sabbatical presentation from a 2022 Sabbatical

Structure Disorder And Magnetic Behavior Of An Olivine-Type Cathode Material, Hamida Hassan, Madalynn Marshall

Symposium of Student Scholars

Our research investigates the structure disorder and magnetic behavior of Li(Mn,Fe)PO₄, an olivine-type material relevant for lithium-ion battery applications. Using single-crystal neutron diffraction at Oak Ridge National Laboratory, we precisely determined Mn and Fe occupancy, revealing a 56% Fe and 44% Mn distribution at the atomic 4c site within the Pnma space group. Additionally, we observed significant lithium site vacancies (78% occupied), influencing the material's electrochemical and magnetic properties. The varying Mn/Fe ratio affected spin reorientation transitions, shifting from antiferromagnetic alignment along the a-axis to the b-axis. Our findings provide crucial insights for optimizing olivine-based cathodes, enhancing energy …

Special Purpose Epr Resonators, Gareth R. Eaton

TeachEPR Submissions

Many types of EPR resonators are described.

Special applications that use various resonators are mentioned.

How To Measure B1, Gareth R. Eaton

TeachEPR Submissions

• CW Methods
• Pulsed EPR Methods

How To Measure Q, Gareth R. Eaton

TeachEPR Submissions

•Frequency bandwidth
–Using spectrometer frequency sweep
–Using a network analyzer

•Ring down following a pulse

Workshop On Quantitative Epr, Dave Barr, Sandra S. Eaton, Gareth R. Eaton, Ralph T. Weber, Patrick Carl, Peter Höfer, Richard W. Quine, George A. Rinard, Colin Mailer

TeachEPR Submissions

Presentations on quantitative EPR at the workshop that preceded the writing of our text, Quantitative EPR.

Presented at the 31^st Annual EPR Symposium in Breckenridge, Colorado on July 27, 2008.

Types Of Epr Resonators, Gareth R. Eaton

TeachEPR Submissions

Fundamental properties of resonators are described with photographs of a variety of actual EPR resonators.

Epr Workshop: Lab Practicals Summary, Gareth R. Eaton

TeachEPR Submissions

• Basics – nitroxide and trityl
• Nitroxides
• Metals - vanadyl
• Pulse
• Rapid scan

Workshop On Rapid Scan Epr, Gareth R. Eaton, Arthur H. Heiss, Deborah Gale Mitchell, Joshua R. Biller, Richard W. Quine, George A. Rinard, Mark Tseitlin, Sandra S. Eaton

TeachEPR Submissions

An introduction to the method of rapid scan EPR is given with emphasis on the design of rapid scan coils, selection of scan parameters, and the reasons that the method improves signal to noise per unit time.

Workshop On Selecting An Epr Resonator, Gareth R. Eaton

TeachEPR Submissions

Guidance is presented to help select a resonator to optimize a measurement. Different resonator types are described with information about resonator Q and microwave power efficiency.

Workshop presented at the 28th International EPR Symposium on July 31, 2005.

Electrochemistry At Work: Bouncing Batteries, Bryant Corbin, James Daniel, Jade Riddle

Fall Showcase for Research and Creative Inquiry

No abstract provided.

Predicting The Reactions Of Cs2, Ocs, And Co2 With Group Iv And Group Vi Transition Metal Oxides, Marissa Shea Blair, Zachary Ryan Lee Phd, David A. Dixon Phd

Posters-at-the-Capitol

Building on a recent serious of high level electronic structure studies of Lewis acid gas reactions with metal oxide sorbents, DFT (B3LYP and ωB97X-D) and CCSD(T) methods are being used to predict the Lewis acid-base addition (physisorption) and formation of metal oxide carbonate/thiocarbonate formation (chemisorption) reactions of CS2, OCS, and CO2 of CS2, OCS, and CO2 with Group IV (MO2)n and Group VI (MO3)n (n = 1 - 3) nanoclusters. For the Group IV oxides, chemisorption to form terminal carbonates and thiocarbonates is predicted to be the most favored, with thiocarbonate ligand binding energies slightly more exothermic than their carbonate …

Photocurable Ionized Vinylimidazole Liquid Salt For Antibacterial Application, Gina Park, Lisa Ahlberg, Robert Zdor

Celebration of Research and Creative Scholarship

There has been an increasing demand for antibacterial dental composite as it can prevent the biofilm formation and the adhesion of bacteria after the treatment causing the consequential cavities. Previous study explored the antibacterial activity of the heterogenous mixture of heterocyclic polymer and resin. It showed limitations as the mixture did not show antibacterial activity since the mixture could only contain a small amount of heterocyclic polymer within the resin due to its inconvenience of shaping and low miscibility. To overcome this limitation, this research focused on synthesizing heterocyclic antibacterial monomer liquid salt and curing it with UV light to …

Determining The Ideal Concentrations Of Ethanol And Propylene Glycol In Ethosomes For Transdermal Delivery Of Vitamin D3, Rebecca Conner

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Vitamin D₃ is an important chemical in the human body, however, many Americans have low levels of this vitamin. There are plenty of oral supplementations for Vitamin D₃ deficiency, but those of older age and busy schedules may struggle to meet the minimum requirement. A recently developed ethosomal transmembrane delivery system (Touitou, 2000), similar to liposomes but also containing ethanol, allows users to apply a gel dermally and have the desired drug or active ingredient reach the bloodstream faster. However, there is considerable variation in the concentration of ethanol and permeation enhancers used. Using an affordable method to …

Carbon Nanotubes Animated, Nicholas Onyemeke

Chemistry Summer Fellows

In this project, I implemented the knowledge about carbon nanotubes into an animated short. The animated short is meant to simplify the research so that anyone can understand regardless of their background in science. The research I did was on how nanotubes can be used in the medical field as a measure to inhibit bacteria growth. A nanotube dye solution was synthesized to inoculate bacteria along with an antibiotic solution with the nanotubes. This was done to observe how well the nanotubes can inhibit bacteria growth without the need for a drug compared to the effectiveness when it has a …

A Comparative Study Of Specific Enthalpy Of Aromatic Hydrocarbons With Simple Carbohydrates, Kohl D. Kervin, Subha Pratihar

ATU Scholars Symposium

Calorimetry is an aspect of chemistry primarily focused on determining the enthalpy of reactions (∆Hrxn). In the bomb calorimetry technique, the heat of combustion of chemical compounds can be measured experimentally. From this data and the application of Hess’s Law, ∆the Hrxn of several chemical reactions can be determined. The technique of bomb calorimetry can be applied to food, fuels, pharmaceuticals, and many other fields. The objective of the present project is to determine the specific enthalpy of various simple carbohydrates (naturally occurring sugars) through bomb calorimetry and compare it with that of aromatic hydrocarbons.

By performing benzoic acid standardization …

Chemical And Biological Investigation Of Sambucus Canadensis And Salvia Officinalis, Elizabeth Martin, Harley Hines, Amber Parnell

ATU Scholars Symposium

New treatments for cancer and bacterial infections are needed, especially because most patients acquire resistance to conventional first-line treatments. Many natural product metabolites exhibit potent activity. Sambucus sp.,elderberry, and Salvia sp., or sage, are well-known shrubs for their therapeutic benefits. This study aims to analyze how secondary metabolites are extracted from the Native American Elderberry, Sambucus canadensis, and Sage, Salvia officinalis. It also aims to investigate the process of vinegar baking of medicinal plants to enhance the chemical space and increase the biological properties. Vinegar-baked and non-vinegar-baked elderberries and sage were utilized to test this theory. A Soxhlet …

Bis(Difluoroborylamidinates) With Flexible Ethylene Bridges As Bifunctional Aggregation-Induced Emitters, Connor Welch

Symposium of Student Scholars

4,4-Difluoro-4-bora-3a,4a-diaza-s-indacenes (BODIPYs) represent one of the most prominent classes of dyes, since they are ubiquitously used in protein and DNA labelling, photodynamic therapies, as luminescent tags, sensors, laser dyes, paint and ink compositions, as well as for electroluminescent devices. [1] This is because of their robustness in terms of photochemical stability, polarity and pH changes of their environment, in particular under physiological conditions. The versatility to introduce multiple functional substituents and ability of BODIPYs to strongly absorb UV-light while providing sharp fluorescence peaks, combined with high quantum yields make these dyes highly attractive for numerous applications. Closely related azaBODIPYs offer …

Study Of Protein Extraction Techniques For M. Foliorum Phages, Lola Sibaud, Anna Elgersma

Student Academic Conference

Characterizing phages is becoming increasingly important in biochemistry and biotechnology due to their potential to treat bacterial infections without need for antibiotics. Last year, students attempted to isolate proteins from Microbacterium foliorum infecting phages Babydotz and Rosadiaz. Proteins were successfully extracted; however, after further analysis it was shown that the obtained proteins belonged to the host bacteria and not the phages. The purpose of this study was to find a method to separate phage from host bacterial debris to successfully isolate phage proteins and analyze them later. Isolating phage proteins could help us characterize more phages and know more about …

Swelling Studies Of Poly(Ionic Liquids) In Different Solvents And Salt Solutions, Pierson Perdue, Ali Alshaikh, Creighton Baltier, Jason E. Bara, Sourav Chatterjee

Scholars Week

Poly(ionic liquid)s (PILs) represented a special class of polymers, which comprised of a polymeric backbone and ionic liquids (ILs) species in each monomeric repeating units. PILs has properties that combined the properties of ionic liquids (ILs) (i.e., high conductivity, better thermal and chemical stability, and tailor-made functionality) with the intrinsic properties of polymer (i.e., mechanical stability). This synergistic property makes PILs a good candidate for various applications such as stable-ion conductors, membranes for gas separations and sorbents. In the past, it was shown that PILs are capable of swelling when dissolved in different ILs but there are few literature reported …

Synthesis And Characterization Of Semi-Interpenetrating And Double Networks Of Sulfonimide- And Imidazolium-Containing Poly(Ionic Liquids), Jeremiah Coughlon, Seth Taylor, Jason Bara, Kevin Miller, Sourav Chatterjee

Scholars Week

In recent years, there has been increased research interest in creating electrically conductive polymer membranes with materials that are widely available and environmentally safe. Herein, we report how polymeric membranes comprised of unique combinations of ionenes and poly(ionic liquids), including a recently developed sulfonimide- and imidazolium-containing methacryloxy-based monomer, were produced via UV photopolymerization. These membranes were specifically tailored to exhibit both ionic conductivity and an affinity for carbon dioxide, which are both crucial characteristics in such applications as electron transport in lithium-ion batteries and gas sorbency in separation techniques. Monomers, such as the aforementioned methacryloxy-based ionic liquid (IL) and C4VIm, …

Physiochemical Properties Of Urethane-Containing Ionic Liquids And Ionenes From A Non-Isocyanate Synthetic Approach, George Timmermann

Scholars Week

Ionic polymers that are designed to contain ionic liquids (ILs) in their backbones have been shown to exhibit a high degree of variability through changing the type of ionic character and the location of the ionic region within the molecule. This large amount of variability in both the structure and characteristics of ILs allows researchers to design task-specific ionic polymers and ILs for a variety of applications including gas separation membranes and solid polymer electrolytes. The synthesis of a specific class of ILs and ionenes through the incorporation of urethane groups with imidazolium rings by reacting carbonyl diimidazole with various …

Strategies For Identifying Important Residues In The Trna Modification Protein Trm732, Alex K. Mullins, Natalie N. Creech, Holly Funk, Michael Guy

Posters-at-the-Capitol

Post-transcriptional tRNA modifications are required for efficient protein translation. In yeast, the Trm7 methyltransferase forms a complex with Trm732 to modify tRNA at position 32. In humans, lack of the human homolog for Trm7, FTSJ1, causes intellectual disability. Little is known about the function of Trm732, although we have shown that one conserved motif in Trm732 is important for tRNA modification. We have identified other residues important for function using two strategies. First, we compared Trm732 proteins of different organisms using protein alignments to determine conserved regions to mutate for testing. We have generated four new Trm732 variants and have …

Determination Of Nitrate In Aqueous Media, Ebony Arauz Tellez, John Bohannon, Rebecca Mills, Virginia Tam, Isabelle Villarreal, Melissa C. Rhoten

Fall Showcase for Research and Creative Inquiry

Determining the amount of inorganic ions in aqueous media is important in the food industry and environmentally. In the environment high levels of ions like nitrate (NO₃^-), nitrite (NO2^-), and phosphate (PO₄^3-) can lead to unhealthy conditions for aquatic species. Similarly, high levels of nitrate and nitrite can cause health issues in humans. One method for determining nitrate levels in aqueous samples involves reducing the nitrate species to nitrite via a redox reaction with finely divided zinc powder followed by conversion to a diazonium salt and complexation with 1-napthylamine to form a …

Is It Useful? Orthophosphate Mapping Of An Excavated Cellar Of A Mid 1700’S Tavern In New London Va, Thomas M. Bender, Randy Lichtenberger

Faculty Publications and Presentations

The partially backfilled cellar of Mead’s Tavern (VDHR # 015-0120) a circa 1760’s building in New London Virginia, was studied by orthophosphate (PO₄³) mapping of the recently exposed, culturally sterile, subsoil floor. Prior studies of the cellar had exposed a hearth along with features that were speculated to be wall partitions for subdivision of the cellar. The full intended purpose for those exposed features is unknown. To further probe that exposed subsoil prior to a major engineering stabilization of the tavern’s foundation, a chemical mapping of surface PO₄^3- levels in the cellar was done. The …