Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Mathematics (2866)
- Numerical Analysis and Computation (1369)
- Computer Sciences (1134)
- Engineering (993)
- Statistics and Probability (986)
-
- Ordinary Differential Equations and Applied Dynamics (853)
- Partial Differential Equations (814)
- Life Sciences (701)
- Other Applied Mathematics (675)
- Education (641)
- Science and Mathematics Education (562)
- Arts and Humanities (551)
- Physics (531)
- Medicine and Health Sciences (520)
- Dynamic Systems (509)
- Higher Education (499)
- History (483)
- Teacher Education and Professional Development (482)
- History of Science, Technology, and Medicine (470)
- Non-linear Dynamics (447)
- Applied Statistics (362)
- Analysis (280)
- Electrical and Computer Engineering (251)
- Control Theory (237)
- Social and Behavioral Sciences (231)
- Other Mathematics (227)
- Mechanical Engineering (217)
- Fluid Dynamics (184)
- Institution
-
- Prairie View A&M University (697)
- Taylor University (475)
- Illinois State University (468)
- University of New Mexico (382)
- Old Dominion University (277)
-
- Virginia Commonwealth University (257)
- Claremont Colleges (256)
- University of Nebraska - Lincoln (249)
- Louisiana State University (232)
- Air Force Institute of Technology (187)
- University of Texas at El Paso (168)
- Wayne State University (161)
- Technological University Dublin (155)
- University of Dayton (144)
- Wright State University (144)
- University of Dar es Salaam (142)
- Embry-Riddle Aeronautical University (134)
- Clemson University (129)
- Portland State University (116)
- Association of Arab Universities (114)
- Montclair State University (108)
- City University of New York (CUNY) (98)
- Western Kentucky University (95)
- Rose-Hulman Institute of Technology (92)
- University of Nevada, Las Vegas (81)
- Utah State University (78)
- Florida Institute of Technology (75)
- COBRA (73)
- Binghamton University (70)
- The University of Southern Mississippi (66)
- Keyword
-
- Mathematics (146)
- Stability (95)
- Differential equations (73)
- Epidemiology (65)
- Machine learning (65)
-
- Optimization (63)
- Finite element method (57)
- Mathematical modeling (51)
- Medicine (49)
- Neutrosophic logic (49)
- Simulation (48)
- Modeling (43)
- Generalized differentiation (42)
- Variational analysis (42)
- Machine Learning (41)
- Numerical analysis (41)
- Other (39)
- Partial differential equations (38)
- Optimal control (37)
- Statistics (36)
- Applied sciences (33)
- Bifurcation (33)
- Algorithms (32)
- COVID-19 (32)
- Inverse problems (31)
- Ecology (28)
- Solitons (28)
- Pure sciences (27)
- Graph theory (25)
- Boundary value problems (23)
- Publication Year
- Publication
-
- Applications and Applied Mathematics: An International Journal (AAM) (697)
- Annual Symposium on Biomathematics and Ecology Education and Research (409)
- Theses and Dissertations (320)
- Branch Mathematics and Statistics Faculty and Staff Publications (211)
- Biology and Medicine Through Mathematics Conference (194)
-
- LSU Doctoral Dissertations (188)
- Department of Mathematics: Faculty Publications (176)
- Mathematics Faculty Publications (172)
- Mathematics & Statistics ETDs (160)
- Mathematics and Statistics Faculty Publications (148)
- Dissertations (141)
- Tanzania Journal of Engineering and Technology (TJET) (131)
- Mathematics & Statistics Faculty Publications (117)
- Departmental Technical Reports (CS) (114)
- Articles (108)
- Electronic Theses and Dissertations (104)
- Mathematics Research Reports (93)
- Journal of Engineering Research (89)
- Mathematics and Statistics Faculty Publications and Presentations (86)
- Publications (85)
- All HMC Faculty Publications and Research (82)
- All Dissertations (81)
- Mathematical Sciences Technical Reports (MSTR) (71)
- Northeast Journal of Complex Systems (NEJCS) (67)
- Faculty Publications (64)
- Summer Conference on Topology and Its Applications (62)
- Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works (58)
- Publications and Research (57)
- Mathematics & Statistics Theses & Dissertations (52)
- Open Access Theses & Dissertations (51)
- Publication Type
- File Type
Articles 3991 - 4020 of 7929
Full-Text Articles in Applied Mathematics
On The Slow Growth And Approximation Of Entire Function Solutions Of Second-Order Elliptic Partial Differential Equations On Caratheodory Domains, Devendra Kumar
Applications and Applied Mathematics: An International Journal (AAM)
In this paper we consider the regular, real-valued solutions of the second-order elliptic partial differential equation. The characterization of generalized growth parameters for entire function solutions for slow growth in terms of approximation errors on more generalized domains, i.e., Caratheodory domains, has been obtained. Moreover, we studied some inequalities concerning the growth parameters of entire function solutions of above equation for slow growth which have not been studied so far.
Modelling Random Antibody Adsorption And Immunoassay Activity, Dana Mackey, Eilis Kelly, Robert Nooney
Modelling Random Antibody Adsorption And Immunoassay Activity, Dana Mackey, Eilis Kelly, Robert Nooney
Articles
One of the primary considerations in immunoassay design is optimizing the concentration of capture antibody in order to achieve maximal antigen binding and, subsequently, improved sensitivity and limit of detection. Many immunoassay technologies involve immobilization of the antibody to solid surfaces. Antibodies are large molecules in which the position and accessibility of the antigen-binding site depend on their orientation and packing density. In this paper we propose a simple mathematical model, based on the theory known as random sequential adsorption (RSA), in order to calculate how the concentration of correctly oriented antibodies (active site exposed for subsequent reactions) evolves during …
Heat Source Thermoelastic Problem In A Hollow Elliptic Cylinder Under Time-Reversal Principle, Pravin Bhad, Vinod Varghese, Lalsingh Khalsa
Heat Source Thermoelastic Problem In A Hollow Elliptic Cylinder Under Time-Reversal Principle, Pravin Bhad, Vinod Varghese, Lalsingh Khalsa
Applications and Applied Mathematics: An International Journal (AAM)
The article investigates the time-reversal thermoelasticity of a hollow elliptical cylinder for determining the temperature distribution and its associated thermal stresses at a certain point using integral transform techniques by unifying classical orthogonal polynomials as the kernel. Furthermore, by considering a circle as a special kind of ellipse, it is seen that the temperature distribution and the comparative study of a circular cylinder can be derived as a special case from the present mathematical solution. The numerical results obtained are accurate enough for practical purposes.
Implementation Of The Matrix Differential Transform Method For Obtaining An Approximate Solution Of Some Nonlinear Matrix Evolution Equations, M. M. Khader, A. Borhanifar
Implementation Of The Matrix Differential Transform Method For Obtaining An Approximate Solution Of Some Nonlinear Matrix Evolution Equations, M. M. Khader, A. Borhanifar
Applications and Applied Mathematics: An International Journal (AAM)
This article introduces the matrix differential transform method (MDTM) to apply to matrix partial differential equations (MPDEs) and employs it for solving matrix Fisher equations, matrix Burgers equations and matrix KdV equations. We show how the MDTM applies to the linear part and nonlinear part of any MPDE and give various examples of MPDEs to illustrate the efficiency of the method. The results obtained are in excellent agreement with the exact solution and show that the proposed method is powerful, accurate, and easy.
Non Markovian Queue With Two Types Service Optional Re-Service And General Vacation Distribution, K. Sathiya, G. Ayyappan
Non Markovian Queue With Two Types Service Optional Re-Service And General Vacation Distribution, K. Sathiya, G. Ayyappan
Applications and Applied Mathematics: An International Journal (AAM)
We consider a single server batch arrival queueing system, where the server provides two types of heterogeneous service. A customer has the option of choosing either type 1 service with probability p1 or type 2 service with probability p2 with the service times follow general distribution. After the completion of either type 1 or type 2 service a customer has the option to repeat or not to repeat the type 1 or type 2 service. As soon as the customer service is completed, the server will take a vacation with probability θ or may continue staying in the system with …
Some Results On F-Simultaneous Chebyshev Approximation, Sh. Al-Sharif, Kh. Qaraman
Some Results On F-Simultaneous Chebyshev Approximation, Sh. Al-Sharif, Kh. Qaraman
Applications and Applied Mathematics: An International Journal (AAM)
Let X be Hausdorff topological vector space and f be a real valued continuous function on X: In this paper we introduce and study the concept of f-simultaneous approximation of a nonempty subset K of X as a generalization to the problem of simultaneous approximation. Further we present some results regarding f-simultaneous approximation in the quotient space.
Density-Dependent Leslie Matrix Modeling For Logistic Populations With Steady-State Distribution Control, Bruce Kessler, Andrew Davis
Density-Dependent Leslie Matrix Modeling For Logistic Populations With Steady-State Distribution Control, Bruce Kessler, Andrew Davis
Mathematics Faculty Publications
The Leslie matrix model allows for the discrete modeling of population age-groups whose total population grows exponentially. Many attempts have been made to adapt this model to a logistic model with a carrying capacity (see [1], [2], [4], [5], and [6]), with mixed results. In this paper we provide a new model for logistic populations that tracks age-group populations with repeated multiplication of a density-dependent matrix constructed from an original Leslie matrix, the chosen carrying capacity of the model, and the desired steady-state age-group distribution. The total populations from the model converge to a discrete logistic model with the same …
Complex Solutions Of The Time Fractional Gross-Pitaevskii (Gp) Equation With External Potential By Using A Reliable Method, Nasir Taghizadeh, Mona N. Foumani
Complex Solutions Of The Time Fractional Gross-Pitaevskii (Gp) Equation With External Potential By Using A Reliable Method, Nasir Taghizadeh, Mona N. Foumani
Applications and Applied Mathematics: An International Journal (AAM)
In this article, modified (G'/G )-expansion method is presented to establish the exact complex solutions of the time fractional Gross-Pitaevskii (GP) equation in the sense of the conformable fractional derivative. This method is an effective method in finding exact traveling wave solutions of nonlinear evolution equations (NLEEs) in mathematical physics. The present approach has the potential to be applied to other nonlinear fractional differential equations. Based on two transformations, fractional GP equation can be converted into nonlinear ordinary differential equation of integer orders. In the end, we will discuss the solutions of the fractional GP equation with external potentials.
Regional Mapping Of Flow And Wall Characteristics Of Intracranial Aneurysms, Juan R. Cebral, Xinjie Duan, Piyusha S. Gade, Bong Jae Chung, Fernando Mut, Khaled Aziz, Anne M. Robertson
Regional Mapping Of Flow And Wall Characteristics Of Intracranial Aneurysms, Juan R. Cebral, Xinjie Duan, Piyusha S. Gade, Bong Jae Chung, Fernando Mut, Khaled Aziz, Anne M. Robertson
Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works
The evolution of intracranial aneurysms (IAs) is thought to be driven by progressive wall degradation in response to abnormal hemodynamics. Previous studies focused on the relationship between global hemodynamics and wall properties. However, hemodynamics, wall structure and mechanical properties of cerebral aneurysms can be non-uniform across the aneurysm wall. Therefore, the aim of this work is to introduce a methodology for mapping local hemodynamics to local wall structure in resected aneurysm specimens. This methodology combines image-based computational fluid dynamics, tissue resection, micro-CT imaging of resected specimens mounted on 3D-printed aneurysm models, alignment to 3D vascular models, multi-photon microscopy of the …
Applying Ahp And Clustering Approaches For Public Transportation Decisionmaking: A Case Study Of Isfahan City, Alireza Salavati, Hossein Haghshenas, Bahador Ghadirifaraz, Jamshid Laghaei, Ghodrat Eftekhari
Applying Ahp And Clustering Approaches For Public Transportation Decisionmaking: A Case Study Of Isfahan City, Alireza Salavati, Hossein Haghshenas, Bahador Ghadirifaraz, Jamshid Laghaei, Ghodrat Eftekhari
Journal of Public Transportation
The main purpose of this paper is to define appropriate criteria for the systematic approach to evaluate and prioritize multiple candidate corridors for public transport investment simultaneously to serve travel demand, regarding supply of current public transportation system and road network conditions of Isfahan, Iran. To optimize resource allocation, policymakers need to identify proper corridors to implement a public transportation system. In fact, the main question is to adopt the best public transportation system for each main corridor of Isfahan. In this regard, 137 questionnaires were completed by experts, directors, and policymakers of Isfahan to identify goals and objectives in …
Mathematical Analysis Of Feedback Targets Of Bmp Signaling In Drosophila Embryonic Development, Yan Luo
Mathematical Analysis Of Feedback Targets Of Bmp Signaling In Drosophila Embryonic Development, Yan Luo
Open Access Theses
Bone morphogenetic proteins (BMPs) drive a range of cellular processes especially in the early stages of embryonic development. This family of proteins acts as one of the most important extracellular signals in development pattern formation across the animal kingdom. Cells in embryos differentiate into different cell types in response to the concentration level of BMP. This complex process is regulated by multiple regulators that serve to tune the signal response.
Extensive experimental and computational research has been performed to analyze BMP regulation in Drosophila, a widely studied model organism, and has advanced our understanding of animal development. Because of …
Integration Over Curves And Surfaces Defined By The Closest Point Mapping, Catherine Kublik, Richard Tsai
Integration Over Curves And Surfaces Defined By The Closest Point Mapping, Catherine Kublik, Richard Tsai
Mathematics Faculty Publications
We propose a new formulation for integrating over smooth curves and surfaces that are described by their closest point mappings. Our method is designed for curves and surfaces that are not defined by any explicit parameterization and is intended to be used in combination with level set techniques. However, contrary to the common practice with level set methods, the volume integrals derived from our formulation coincide exactly with the surface or line integrals that one wishes to compute. We study various aspects of this formulation and provide a geometric interpretation of this formulation in terms of the singular values of …
Computational Methods For Asynchronous Basins, Ian H. Dinwoodie
Computational Methods For Asynchronous Basins, Ian H. Dinwoodie
Mathematics and Statistics Faculty Publications and Presentations
For a Boolean network we consider asynchronous updates and define the exclusive asynchronous basin of attraction for any steady state or cyclic attractor. An algorithm based on commutative algebra is presented to compute the exclusive basin. Finally its use for targeting desirable attractors by selective intervention on network nodes is illustrated with two examples, one cell signalling network and one sensor network measuring human mobility.
Modern Fair-Weather And Storm Sediment Transport Around Ship Island, Mississippi: Implications For Coastal Habitats And Restoration Efforts, Eve Rettew Eisemann
Modern Fair-Weather And Storm Sediment Transport Around Ship Island, Mississippi: Implications For Coastal Habitats And Restoration Efforts, Eve Rettew Eisemann
Master's Theses
The Mississippi – Alabama barrier island chain is experiencing accelerated sea level rise, decreased sediment supply, and frequent hurricane impacts. These three factors drive unprecedented rates of morphology change and ecosystem reduction. All islands in the chain have experienced land loss on the order of hectares per year since records began in the 1840s. In 1969, Hurricane Camille impacted as a Category 5, breaching Ship Island, and significantly reduced viable seagrass habitat. Hurricane Katrina impacted as a Category 3 in 2005, further widening Camille Cut. To better understand the sustainability of these important islands and the ecosystems they support, sediment …
Fast Method Of Particular Solutions For Solving Partial Differential Equations, Anup Raja Lamichhane
Fast Method Of Particular Solutions For Solving Partial Differential Equations, Anup Raja Lamichhane
Dissertations
Method of particular solutions (MPS) has been implemented in many science and engineering problems but obtaining the closed-form particular solutions, the selection of the good shape parameter for various radial basis functions (RBFs) and simulation of the large-scale problems are some of the challenges which need to overcome. In this dissertation, we have used several techniques to overcome such challenges.
The closed-form particular solutions for the Matérn and Gaussian RBFs were not known yet. With the help of the symbolic computational tools, we have derived the closed-form particular solutions of the Matérn and Gaussian RBFs for the Laplace and biharmonic …
A Traders Guide To The Predictive Universe- A Model For Predicting Oil Price Targets And Trading On Them, Jimmie Harold Lenz
A Traders Guide To The Predictive Universe- A Model For Predicting Oil Price Targets And Trading On Them, Jimmie Harold Lenz
Doctor of Business Administration Dissertations
At heart every trader loves volatility; this is where return on investment comes from, this is what drives the proverbial “positive alpha.” As a trader, understanding the probabilities related to the volatility of prices is key, however if you could also predict future prices with reliability the world would be your oyster. To this end, I have achieved three goals with this dissertation, to develop a model to predict future short term prices (direction and magnitude), to effectively test this by generating consistent profits utilizing a trading model developed for this purpose, and to write a paper that anyone with …
A Mathematical Model For Micropolar Fluid Flow Through An Artery With The Effect Of Stenosis And Post Stenotic Dilatation, R. B. Vijaya, K. M. Prasad, C. Umadevi
A Mathematical Model For Micropolar Fluid Flow Through An Artery With The Effect Of Stenosis And Post Stenotic Dilatation, R. B. Vijaya, K. M. Prasad, C. Umadevi
Applications and Applied Mathematics: An International Journal (AAM)
The effects of both stenosis and post stenotic dilatation have been studied on steady flow of
micropolar fluid through an artery. Assuming the stenosis to be mild, the equations governing the
flow of the proposed model are solved. Closed form expressions for the flow characteristics such
as velocity, pressure drop, and volumetric flow rate, resistance to the flow and wall shear stress
are derived. The effects of various parameters on resistance to the flow and wall shear stress
have been analyzed through the graphs. It is found that the resistance to the flow increases with
the height and length of …
Projective-Planar Graphs With No K3,4-Minor. Ii., John Maharry, Dan Slilaty
Projective-Planar Graphs With No K3,4-Minor. Ii., John Maharry, Dan Slilaty
Mathematics and Statistics Faculty Publications
The authors previously published an iterative process to generate a class of projectiveplanar K3,4-free graphs called ‘patch graphs’. They also showed that any simple, almost 4-connected, nonplanar, and projective-planar graph that is K3,4-free is a subgraph of a patch graph. In this paper, we describe a simpler and more natural class of cubic K3,4- free projective-planar graphs which we call M¨obius hyperladders. Furthermore, every simple, almost 4-connected, nonplanar, and projective-planar graph that is K3,4-free is a minor of a M¨obius hyperladder. As applications of these structures we determine the page number of patch graphs and of M¨obius hyperladders.
Markov Chain Profit Modelling And Evaluation Between Two Dissimilar Systems Under Two Types Of Failures, Saminu I. Bala, Ibrahim Yusuf
Markov Chain Profit Modelling And Evaluation Between Two Dissimilar Systems Under Two Types Of Failures, Saminu I. Bala, Ibrahim Yusuf
Applications and Applied Mathematics: An International Journal (AAM)
No abstract provided.
A 10-Point Approximating Subdivision Scheme Based On Least Squares Technique, Ghulam Mustafa, Muhammad T. Iqbal
A 10-Point Approximating Subdivision Scheme Based On Least Squares Technique, Ghulam Mustafa, Muhammad T. Iqbal
Applications and Applied Mathematics: An International Journal (AAM)
In this paper, a 10-point approximating subdivision scheme is presented. Least squares technique for fitting the polynomial of degree 9 to data is used to develop this scheme. The proposed strategy can be used to generate a family of schemes. The important characteristics of the scheme are also discussed. Graphical efficiency of the scheme is shown by applying it on different types of data.
Impact Of Permeable Lining Of The Wall On The Peristaltic Flow Of Herschel Bulkley Fluid, G. C. Sankad, Asha Patil
Impact Of Permeable Lining Of The Wall On The Peristaltic Flow Of Herschel Bulkley Fluid, G. C. Sankad, Asha Patil
Applications and Applied Mathematics: An International Journal (AAM)
The peristaltic motion is modeled for the Herschel Bulkley fluid, considered to flow in a non-uniform inclined channel. The channel wall is supposed to be lined with a non-erodible porous material. The flow is considered to be moving in a wave frame of reference moving with same velocity as of the sinusoidal wave. Low Reynolds number and long wave length assumptions are made to solve the model. Analytical solution is obtained for the pressure difference and also for the frictional force. Graphs are plotted, using Mathematica software, for both the results of pressure difference and frictional force against time average …
On The Exchange Property For The Mehler-Fock Transform, Abhishek Singh
On The Exchange Property For The Mehler-Fock Transform, Abhishek Singh
Applications and Applied Mathematics: An International Journal (AAM)
The theory of Schwartz Distributions opened up a new area of mathematical research, which in turn has provided an impetus in the development of a number of mathematical disciplines, such as ordinary and partial differential equations, operational calculus, transformation theory and functional analysis. The integral transforms and generalized functions have also shown equivalent association of Boehmians and the integral transforms. The theory of Boehmians, which is a generalization of Schwartz distributions are discussed in this paper. Further, exchange property is defined to construct Mehler-Fock transform of tempered Boehmians. We investigate exchange property for the Mehler-Fock transform by using the theory …
On The Propagation Of Atmospheric Gravity Waves In A Non-Uniform Wind Field: Introducing A Modified Acoustic-Gravity Wave Equation, Ahmad Talaei
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
Atmospheric gravity waves play fundamental roles in a broad-range of dynamical processes extending throughout the Earth’s neutral atmosphere and ionosphere. In this paper, we present a modified form for the acoustic-gravity wave equation and its dispersion relationships for a compressible and non-stationary atmosphere in hydrostatic balance. Importantly, the solutions have been achieved without the use of the well-known Boussinesq approximation which have been used extensively in previous studies.
We utilize the complete set of governing equations for a compressible atmosphere with non-uniform airflows to determine an equation for vertical velocity of possible atmospheric waves. This intricate wave equation is simplified …
Spreading Speeds Along Shifting Resource Gradients In Reaction-Diffusion Models And Lattice Differential Equations., Jin Shang
Electronic Theses and Dissertations
A reaction-diffusion model and a lattice differential equation are introduced to describe the persistence and spread of a species along a shifting habitat gradient. The species is assumed to grow everywhere in space and its growth rate is assumed to be monotone and positive along the habitat region. We show that the persistence and spreading dynamics of a species are dependent on the speed of the shifting edge of the favorable habitat, c, as well as c*(∞) and c*(−∞), which are formulated in terms of the dispersal kernel and species growth rates in both directions. When …
Effects Of Cell Cycle Noise On Excitable Gene Circuits, Alan Veliz-Cuba, Chinmaya Gupta, Matthew R. Bennett, Krešimir Josić, William Ott
Effects Of Cell Cycle Noise On Excitable Gene Circuits, Alan Veliz-Cuba, Chinmaya Gupta, Matthew R. Bennett, Krešimir Josić, William Ott
Mathematics Faculty Publications
We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect intensifies in the presence of transcriptional delay. We explain this concentration effect with a three-states stochastic model. For genetic oscillators, we quantify the temporal correlations between daughter cells induced by cell division. Temporal correlations must be captured properly in order to accurately quantify noise sources within gene networks.
Simulating The Spread Of The Common Cold, R. Corban Harwood
Simulating The Spread Of The Common Cold, R. Corban Harwood
Faculty Publications - Department of Mathematics
This modeling scenario guides students to simulate and investigate the spread of the common cold in a residence hall. An example floor plan is given, but the reader is encouraged to use a more relevant example. In groups, students run repeated simulations, collect data, derive a differential equation model, solve that equation, estimate parameter values by hand and through regression, visually evaluate the consistency of the model with their data, and present their results to the class.
Robustness Of The Potential And Flux Landscapes In Fission Yeast Cell Cycle Networks, Xiaosheng Luo
Robustness Of The Potential And Flux Landscapes In Fission Yeast Cell Cycle Networks, Xiaosheng Luo
Theses and Dissertations
Using fission yeast cell cycle as an example, we uncovered that the non-equilibrium network dynamics and global properties are determined by two essential features: the potential landscape and the flux landscape. While potential landscape quantifies the probabilities of different states forming hills and valleys, the flux landscape quantifies the probability fluxes of different loops flowing through states. These two landscapes can be quantified through the decomposition of the dynamics into the detailed balance preserving part and detailed balance breaking non-equilibrium part. While the funneled potential landscape is often crucial for the stability of the single attractor networks, we have uncovered …
Convolutions And Green’S Functions For Two Families Of Boundary Value Problems For Fractional Differential Equations, Paul W. Eloe, Jeffrey T. Neugebauer
Convolutions And Green’S Functions For Two Families Of Boundary Value Problems For Fractional Differential Equations, Paul W. Eloe, Jeffrey T. Neugebauer
Mathematics Faculty Publications
We consider families of two-point boundary value problems for fractional differential equations where the fractional derivative is assumed to be the Riemann-Liouville fractional derivative. The problems considered are such that appropriate differential operators commute and the problems can be constructed as nested boundary value problems for lower order fractional differential equations. Green's functions are then constructed as convolutions of lower order Green's functions. Comparison theorems are known for the Green's functions for the lower order problems and so, we obtain analogous comparison theorems for the two families of higher order equations considered here. We also pose a related open question …
Network Inference Driven Drug Discovery, Gergely Zahoránszky-Kőhalmi, Tudor I. Oprea, Cristian G. Bologa, Subramani Mani, Oleg Ursu
Network Inference Driven Drug Discovery, Gergely Zahoránszky-Kőhalmi, Tudor I. Oprea, Cristian G. Bologa, Subramani Mani, Oleg Ursu
Biomedical Sciences ETDs
The application of rational drug design principles in the era of network-pharmacology requires the investigation of drug-target and target-target interactions in order to design new drugs. The presented research was aimed at developing novel computational methods that enable the efficient analysis of complex biomedical data and to promote the hypothesis generation in the context of translational research. The three chapters of the Dissertation relate to various segments of drug discovery and development process.
The first chapter introduces the integrated predictive drug discovery platform „SmartGraph”. The novel collaborative-filtering based algorithm „Target Based Recommender (TBR)” was developed in the framework of this …
Generalized Least-Powers Regressions I: Bivariate Regressions, Nataniel Greene
Generalized Least-Powers Regressions I: Bivariate Regressions, Nataniel Greene
Publications and Research
The bivariate theory of generalized least-squares is extended here to least-powers. The bivariate generalized least-powers problem of order p seeks a line which minimizes the average generalized mean of the absolute pth power deviations between the data and the line. Least-squares regressions utilize second order moments of the data to construct the regression line whereas least-powers regressions use moments of order p to construct the line. The focus is on even values of p, since this case admits analytic solution methods for the regression coefficients. A numerical example shows generalized least-powers methods performing comparably to generalized least-squares methods, …