Applied Mathematics Commons^™

Traveling Wave Fronts For Sir Epidemic Models With Nonlocal Dispersal And Delayed Effects, Ashley Evette Embry

Theses and Dissertations

This dissertation investigates traveling wave solutions for two classes of delayed nonlocal dispersal susceptible--infected--recovered (SIR) epidemic models incorporating biologically realistic mechanisms such as delayed infectivity, delayed dispersal, nonlocal transmission, demographic turnover, and nonlinear incidence effects. These models extend classical spatial epidemic frameworks by allowing long-range population movement through nonlocal dispersal operators and incorporating temporal memory into both diffusion and transmission processes. The primary objective is to establish the existence of traveling wave solutions connecting disease-free equilibria to endemic states and to characterize threshold conditions governing epidemic propagation. The simultaneous presence of nonlocal dispersal, multiple delays, and non-monotone nonlinear incidence terms …

A New Approach To Generate Combinatorial Patterns In Logical Analysis Of Data And Its Application To Predict College Retention, Salihah Ahmed E. Jaafari

Theses and Dissertations

Student retention and degree completion remain central challenges for higher-education institutions, with significant implications for student success, institutional effectiveness, and public accountability. While advances in predictive analytics have enabled earlier identification of students at risk of withdrawal, many commonly used machine learning approaches suffer from limited interpretability, constraining their practical usefulness for advising, intervention, and policy decision making. This dissertation addresses the problem of predicting student persistence by developing and evaluating optimization based, interpretable classification models within the Logical Analysis of Data (LAD) framework. Building on existing LAD formulations, this research introduces two novel pattern generation models, the Best Term …

Multivariate Time-Series Forecasting Of 24-Hour Ambulatory Blood Pressure Using Long Short-Term Memory And Temporal Fusion Transformers, Sebastian Alejos Torres

Theses and Dissertations

Time series play a central role in healthcare by enabling continuous patient monitoring and forecasting of physiological and clinical measurements. Traditional models, such as autoregressive integrated moving average (ARIMA), are limited in capturing nonlinear dynamics and irregular sampling. In this study, we develop and evaluate Long Short-Term Memory (LSTM) networks and Temporal Fusion Transformers (TFTs) to forecast 24-hour ambulatory systolic and diastolic blood pressure (SBP and DBP) time series enriched with demographic and clinical features. Mean absolute error (MAE), root mean squared error (RMSE), mean absolute percentage error (MAPE), and R² were used to evaluate predictive accuracy and temporal pattern …

Adaptive Artificial Potential Field Guidance And Control For Autonomous Docking With Uncooperative And Unknown Spacecraft, Steven Holmberg

Theses and Dissertations

The increasing demand for on-orbit servicing (OOS), active debris removal (ADR), and space domain awareness (SDA) missions has increased the need for autonomous spacecraft rendezvous and proximity operations (RPO) with uncooperative and unknown targets. Traditional guidance and control methods are typically designed for cooperative systems with known geometry and state information. This work builds on previous research to develop and evaluate an artificial potential field (APF)-based control framework capable of autonomous operation with minimal prior target knowledge and applicability to both relatively static and tumbling spacecraft.

The proposed APF formulation incorporates established safety constructs from cooperative docking systems, including an …

Type Ii Diabetes Treatment Comparison Via Compartment Modeling, Abigail M. Collins

Theses and Dissertations

Type II diabetes mellitus affects one in ten adults worldwide, yet the effects of treatment type and adherence level on developing complications and quality of life have not been well characterized at the population level, and mathematical modeling offers a structured way to examine these dynamics. This thesis adapts the Boutayeb et al. (2004) model to incorporate dynamic treatment types and levels of adherence, producing nine scenarios in which complication development rate and complication recovery rate differed, to compare peak complications and quality of life across treatment and adherence conditions. Using a system of ordinary differential equations and compartment modeling, …

Managing Multi-Drug Resistance: An Evolutionary Game Theory And Optimal Control Approach, Shukhrat Nasrulloev

Theses and Dissertations

Multi-drug resistance is an evolutionary process in which treatment eliminates sensitive cells, allowing resistant clones to dominate. This thesis investigates this process using a framework integrating population dynamics, evolutionary game theory, and optimal control theory. We develop a two-population logistic growth model describing competition between drug-sensitive and drug-resistant cells under treatment, construct dose-dependent payoff matrices and replicator dynamics to characterize evolutionary competition, and derive a critical drug level D_crit = (r_S - rR)/(dS - d_R) at which resistant cells gain a fitness advantage. An optimal control problem is formulated via Pontryagin's Maximum Principle to identify schedules …

Data-Driven Partitioning In Distributed Optimization For Networked Systems, Prosper Azameti

Theses and Dissertations

The convergence behavior of distributed optimal power flow (OPF) depends strongly on how the power network is partitioned into regions. Classical graph-based methods such as METIS are widely used, but they rely mainly on static topological criteria and do not explicitly incorporate operating-point-dependent information that may affect distributed optimization performance. This thesis develops a data-driven partitioning framework for distributed OPF using graph neural networks (GNNs). Each OPF scenario is represented as a graph in which buses are nodes and transmission lines are edges. Node and edge features capture both structural and operational characteristics of the network. Partition prediction is formulated …

Mathematical Models With Clinical Applications For Improving Health Outcomes, Helen Harris

Theses and Dissertations

In clinical settings, patients are exposed to many risks and stressors that could result in adverse health outcomes. Here we present mathematical models that seek to address these risks. First, we present a Markov Chain model to investigate the effect of medication reconciliation (MR) completion on patient health outcomes in the intensive care unit. Using this model, we simulate the annual incidence of adverse drug events (ADEs) for three different ADE rates. Based on the simulated results, we conduct a cost-benefit analysis for various levels of compliance to determine the financial implications of increasing MR completion depending on the baseline …

The Effects Of Overwash On Barrier Island Evolution And Building A Barrier Island Measure Of Resistance, Beth Thomas

Theses and Dissertations

Barrier islands are critical for coastal communities, as they serve as a natural buffer against storm surge, waves, and the effects of rising sea levels, protecting life and property. These islands continuously evolve due to both normal and severe environmental conditions; global warming makes it increasingly difficult to predict the evolution of these islands due to increases in storm frequency and intensity. We present a cellular model of barrier island evolution consisting of biotic and abiotic processes including the effects of vegetation, wind, ocean currents, and gravity. The model is used to predict the future evolution of barrier islands off …

A Mathematical Frameworks For Singular, Nonlinear Phenomena: Applications To Nematocyst Firing And Inhomogeneous Nls With Coulomb Potential, Abdulrahman Alharbi

Theses and Dissertations

Nematocysts are specialized cellular organelles found in all cnidarians, including corals and jellyfish, as well as in some single-celled protists such as dinoflagellates. These organelles display remarkable diversity in morphology and function, playing roles in prey capture and defense. The firing of a nematocyst is one of the fastest accelerations in nature, yet the underlying physical mechanisms remain not fully understood. In this work, we address key questions: how sufficient force is generated to overcome the fluid boundary layer, whether fluid–structure interaction models can reproduce observed dynamics, and what mechanisms trigger discharge.

Our research investigates models based on osmotic pressure …

Spectral Methods And Wavelets In Quantitative Finance Problems, Davood Damircheli

Theses and Dissertations

This dissertation leverages advanced spectral methods and wavelet techniques to address complex quantitative finance models, enhancing the computation of financial derivatives and risk assessments. Building on foundational studies, this research extends these methods to broader, intricate financial contexts. The first section explores fractional-order generalized Chebyshev wavelets (FOCW) applied to fractional advection equations, relevant in both mathematics and physics. Using a regularized beta function to compute the Riemann-Liouville fractional integral operator, this study introduces a novel numerical scheme with robust accuracy, confirmed through error analysis and empirical tests. The second part examines the fractional Black-Scholes equations for option pricing under subdiffusive …

Clustering 24-Hour Ambulatory Blood Pressure Time Series With Dynamic Time Warping And Time Warp Edit Distance, John Knight

Theses and Dissertations

Ambulatory blood pressure monitoring (ABPM) captures dynamic circadian changes in blood pressure (BP) that are not reflected in static clinic readings. This study applied time-series clustering with two elastic distance measures—Dynamic Time Warping (DTW) and Time Warp Edit Distance (TWED)—to identify distinct phenotypes in 2,155 24-hour ABPM time series from participants in the Maracaibo Aging Study. DTW and TWED both yielded three clusters corresponding to non-dipping, moderate-dipping, and strong-dipping patterns. The non-dipping group showed elevated nighttime BP, associated with greater cardiovascular and cognitive risk, while the strong-dipping group was associated with higher education and younger age in baseline clinic measurements. …

Quantum Entanglement As A Resource For Coordinating Navigation, Aamir Ahmad

Theses and Dissertations

John Clauser, Michael Horne, Abner Shimony, and Richard Holt (CHSH) originally formulated the CHSH game as an experiment to establish entanglement as a quantum mechanical phenomenon that could not be predicted by classical theories. I will apply the quantum strategy used in the CHSH game to demonstrate that it also establishes a structure that employs entanglement as a resource to enable coordination without communication in the context of navigation.

Advancing Real-World Implementation Of The Well Optimized Linear Finder (Wolf) High-Speed Atmospheric Turbulence Compensation Method, Timothy Evan Coon

Theses and Dissertations

This dissertation advances the real-world implementation of the Well Optimized Linear Finder (WOLF) method for high-speed Atmospheric Turbulence Compensation (ATC). Atmospheric turbulence introduces phase aberrations into optical wavefronts and degrades image quality in terrestrial imaging systems. Traditional phase diversity methods are computationally intensive and poorly suited to real-time operation. The WOLF method addresses these limitations through a novel, point-wise formulation of the optical transfer function (OTF) as a structured autocorrelation of the generalized pupil function (GPF). This formulation enables the estimation of phase aberrations at individual spatial coordinates with distributed computational complexity.

The research begins by developing a MATLAB-based simulation …

Statistical Power To Detect Simultaneous Violation Of Proportionality In Hazards And Additive Assumption In Cox Regression Model, Lawrence Mensah Agbota

Theses and Dissertations

The Cox proportional hazards regression model is a widely employed semi-parametric tool in epidemiological and medical research for analyzing time-to-event data and assessing the relationship between patient survival times and one or more predictors. This method involves regression analyses necessitating a meticulous approach to careful examination of the covariates and the relationship among covariates included in the model through a series of critical decisions and steps. Violation of the additivity of the effects and the proportionality in hazards (PH) assumption can lead to biased results and misleading scientific findings. We conducted a Monte Carlo simulation study to assess the performance …

Predicting Enzyme-Substrate Association Using Heterogeneous Knowledge Graph, Jannatul Ferdaus

Theses and Dissertations

Phosphorylation and dephosphorylation are dynamic processes that control many aspects of cellular activity, such as metabolic pathways, cell cycle progression, and signal transduction. Protein activity and interactions are modulated by the reversible addition or removal of phosphate groups, which allows cells to react abruptly to evolving conditions. Although kinase-specific phosphorylation site prediction has advanced, phosphatase-specific dephosphorylation site computational prediction is still a major obstacle that prevents us from fully comprehending the extent of cellular regulation. In this study, we constructed a knowledge graph for the prediction of enzymes (kinases and phosphatases) and their associated substrates with specific phosphosites. As part …

Sequential Data Modeling Of Influenza A Via Traditional, Dwt-Gpr Hybrid, And Deep Learning Architectures, Edmund Fosu Agyemang

Theses and Dissertations

Influenza A is responsible for 290,000 to 650,000 respiratory deaths a year, though this estimate is an improvement from years past due to improved sanitation, healthcare practices, and vaccination programs. In this study, we perform a comparative analysis of traditional, deep-learning and discrete wavelet (DWT)-Gaussian Process (GP) hybrid models to predict Influenza A outbreaks. Using historical data from January 2009 to December 2023, we compared the performance of traditional ARIMA and ETS models, four variants of DWT-GPR models and six distinct deep learning architectures: Simple RNN, LSTM, GRU, BiLSTM, BiGRU and Transformer. The results reveal a clear superiority of all …

Equiangularity From Compatible Orthobiangularity, Tyler J. Myers

Theses and Dissertations

An equiangular tight frame (ETF) is an equal norm sequence of vectors in a Hilbert space whose coherence achieves equality in the Welch bound. Such sequences necessarily have minimal coherence and thus are, in some sense, as "spread out" in space as possible. ETFs have a variety of applications, such as compressed sensing and waveform design. The main problem in the study of ETFs is determining the pairs (D, N) for which an ETF with N vectors in a D-dimensional space exists. Real ETFs are moreover equivalent to a special subset of a well-studied class of graphs known as strongly …

Applications Of The Mathieu Groups And Information Theory In Dna Encoding Functions, Juan C. Nava Jr

Theses and Dissertations

A foundational idea in mathematics lies in breaking down existing components into their bare fundamentals. As evidenced by prime numbers and composites, we learn this idea at an early age. Categorizing these broken-down components into their simplest form allows mathematicians to construct proofs from emergent patterns. John Conway’s Atlas of Finite Groups in the 1990s was particularly concerned with the categorization of structures known as groups. There are certain axioms a group must adhere to, which amount to the retention of symmetry; ultimately a group helps us to better understand symmetric actions performed on a set with a binary operation. …

Existence Of Traveling Waves In A Predator-Prey Invasion Model With Nonlocal Dispersal And Delayed Effects In Dispersal, Austin Simms

Theses and Dissertations

We investigate the existence and stability of traveling wave solutions in a predator--prey population model that incorporates both nonlocal dispersal and time-delayed interactions. The problem arises when species distributions and feeding or reproduction processes do not respond instantaneously, but rather exhibit lags in space and time. Our aim is to understand how these delays and nonlocal effects impact the wavefront speed and the eventual establishment of a predator population in previously prey-dominated regions. To accomplish this, we derive a PDE--integro--delay system from ecological considerations of prey self-regulation, predator ratio dependence, and jump-type dispersal kernels. We then employ a traveling wave …

The Herzog-Takayama Resolution Over A Skew Polynomial Ring, Linoy Utkina

Theses and Dissertations

Let k be a field, and let I be a monomial ideal in the polynomial ring R = k[x1,..., xn]. In her thesis, Taylor introduced a complex that yields a finite free resolution of R/I as an R-module. Building on Taylor’s work, Ferraro, Martin, and Moore extended this construction to monomial ideals in skew polynomial rings. Because the Taylor resolution is typically not minimal, subsequent research efforts went into identifying specific classes of ideals whose minimal free resolutions can be constructed more simply. In 1990, Eliahou and Kervaire devised an approach for handling minimal resolutions of …

Congruences In Arithmetic Progression For Coefficients Of Gaussian Polynomials And Crank Statistics, Joselyne Aniceto

Theses and Dissertations

The study of partition congruences, inspired by Ramanujan’s discoveries for ��(��) over a century ago, remains a central topic in this field. This dissertation examines congruence properties in two restricted partition functions: ��(��,��), which counts partitions of �� into at most �� parts, and ��(��,��,��), which further limits the size of the largest part to be at most ��. Building on Kronholm’s 2007 result, now known as the Interval Theorem, and a recent result by Eichhorn, Engle, and Kronholm, we establish new infinite families of congruences for ��(��,��,��). This dissertation extends not only the recent results of Eichhorn, Engle, …

Implementing And Evaluating An Ai-Powered Visual Decision Support System To Improve Antibiotic Usage Among Physicians With A Built-In Early Warning System, Akua Sekyiwaa Osei-Nkwantabisa

Theses and Dissertations

The widespread misuse and excessive prescription of antibiotics have played a pivotal role in the emergence and proliferation of antibiotic-resistant bacteria, posing a critical global public health crisis. Addressing this challenge necessitates innovative solutions that enhance antimicrobial stewardship. This study presents the development and implementation of a visual decision support system designed to monitor and optimize antibiotic usage among healthcare providers. The proposed system integrates advanced machine learning algorithms with real-time data analytics to provide a dynamic, evidence-based decision support tool. Specifically, a neural network model was developed after evaluating multiple machine learning approaches, including Random Forest, Logistic Regression and …

A Dg-Algebra Structure With Divided Powers On The Generalized Taylor Resolution, Raul F, Alvarez

Theses and Dissertations

This thesis investigates the construction of a DG Γ-algebra structure on the Generalized Taylor Resolution (GTR) associated with monomial ideals. The classical Taylor resolution is known for providing a free but generally non-minimal resolution, leading to computational challenges and inefficiencies in algebraic analysis. In contrast, the GTR preserves essential algebraic structures while optimizing the resolution process, offering a more efficient and comprehensive framework for studying monomial ideals.

We introduce a novel DG Γ-structure that incorporates divided powers into the GTR, enhancing its multiplicative and homological properties. This structure preserves strict graded commutativity and is fully compatible with the differential graded …

Stability Of Space-Time Finite Element Discretizations Of Subdiffusive Time-Fractional Differential Equations, Gabriel Kenneth Staton

Theses and Dissertations

The study of anamolous diffusion, and in particular of subdiffusive time-fractional differential equations, is of great interest for its ability to describe transport of particles through porous media. The time-fractional derivatives in these problems are nonlocal, which notably hinders performance of classical time-stepping methods. As a result, there is significant interest in using simultaneous space-time discretizations for these subdiffusive problems, which have the additional benefit of significantly relaxing the regularity requirements for candidate solutions. These types of Petrov-Galerkin schemes require a careful choice of discretized trial and test spaces in order to guarantee stability; in particular, the usual Galerkin choice …

Analyzing And Comparing Refinement Indicators For Rbf-Fd Adaptive Algorithms, Anders R. Johnson

Theses and Dissertations

Recent progress has been made in the development of collocation-based iterative algorithms that approximate solutions to PDEs. These algorithms rely on the ability to identify regions within a domain where a finer discretization is required. Such iterative algorithms are beneficial particularly when solution functions have highly localized behavior. This thesis proposes an indicator for node refinement that is constructed by approximating the forward error. This proposed indicator also helps to establish confidence in the accuracy of a given solution estimate. The proposed error estimator is theoretically examined and compared with contemporary refinement indicators. It is shown that an iterative algorithm, …

Impact Of Stochastic Travel Times On The Military Port Selection Problem: A Stochastic Programming Approach, William M. Titus

Theses and Dissertations

This research models and analyzes the impact of stochastic travel times on port selection during a large-scale mobilization of equipment from continental United States installations to deployment locations using sealift ships. A stochastic mixed-integer programming model is developed to minimize the average arrival time of equipment into theater. The model is solved using Sample Average Approximation. In the first stage, the model selects ports to open and assigns installations, equipment, and ships to open ports. In the second stage, travel times are realized, and equipment is assigned to specific ships that are scheduled to depart. Results show that the marginal …

Grassmannian Codes From Stratified Frames, William J. Brinkley

Theses and Dissertations

An equichordal tight fusion frame (ECTFF) is a finite sequence of equi-dimensional subspaces of a Euclidean space that achieves equality in Conway, Hardin and Sloane's simplex bound. Every ECTFF is an optimal Grassmannian code with respect to the chordal distance. We introduce a method for constructing an ECTFF from any finite sequence of unit norm tight frames that happen to be stratified in a certain sense. We moreover show how to construct stratified unit norm tight frames from a difference family for a finite abelian group, as well as from a suitable combination of a resolvable balanced incomplete block design …

Advancing Defense Software Cost Estimation Through Regression, Probabilistic, And Machine Learning Models, Stephen D. Chatterton

Theses and Dissertations

Accurately estimating software costs is critical for effective project management within the Department of Defense (DoD), where early decisions shape resource allocation and risk management. This work evaluates regression-based Cost Estimating Relationships (CERs), probabilistic models, and machine learning techniques to address limitations of traditional estimation methods. Using records from two DoD repositories, the analysis applied Ordinary Least Squares (OLS) regression, Multinomial Logistic Regression (MLR), Random Forest, and neural networks to model and classify software costs, with key predictors including Source Lines of Code (SLOC), Equivalent Source Lines of Code (ESLOC), and programming hours. The findings highlight strengths and trade-offs of …

Investigation Of Node Refinement Methods In Local Adaptive Kernel Based Approximation, Shelby W. Woodrum

Theses and Dissertations

This thesis explores computational efficiency and accuracy of six node refinement methods for local adaptive kernel-based approximations of solutions to the two-dimensional Poisson equation. Using an adaptive kernel-based approximation algorithm, this research investigates performance of Delaunay triangulation-based methods (shifted barycenters and edge midpoints), refinement via approximate Fekete and discrete Leja points, and a meshless predefined shift refinement method across two domains with varying complexities. Computational experiments reveal that Delaunay triangulation-based methods achieve a practical balance between accuracy and efficiency, particularly in square domains. Refinement via approximate Fekete and discrete Leja points produce accurate results but incur greater computational costs, making …