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Cancer Care Annual Report 2022-2023, Children's Mercy Kansas City

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Kansas City, a pediatric medical center. This year’s report focuses on Brain Tumors.

Children's Mercy Annual Report 2023, Children's Mercy Kansas City

Children's Mercy Annual Reports

Annual report for Children's Mercy Kansas City in Kansas City MO, a pediatric medical center.

Outpatient Medications Deimplemented By The Aap Bronchiolitis Guidelines: An Umbrella Review Of Meta-Analyses, Larry Mellick, Paul Walsh, Clista Clanton, Sarathi Kalra, Shane Mckinney

University Research Data and Datasets

OBJECTIVE: To systematically perform an umbrella review all meta-analyses that included outpatient sub-analyses or network meta-analyses with medication treatment comparisons to study the clinical benefits of these deimplemented medications in the outpatient setting.

Mechanosensory Encoding In Ex Vivo Muscle–Nerve Preparations, Stephen N. Housley, Evelyn A. Gardolinski, Paul Nardelli, J'Ana Reed, Mark M. Rich, Timothy C. Cope

Neuroscience, Cell Biology & Physiology Faculty Publications

Our objective was to evaluate an ex vivo muscle-nerve preparation used to study mechanosensory signalling by low threshold mechanosensory receptors (LTMRs). Specifically, we aimed to assess how well the ex vivo preparation represents in vivo firing behaviours of the three major LTMR subtypes of muscle primary sensory afferents, namely type Ia and II muscle spindle (MS) afferents and type Ib tendon organ afferents. Using published procedures for ex vivo study of LTMRs in mouse hindlimb muscles, we replicated earlier reports on afferent firing in response to conventional stretch paradigms applied to non-contracting, that is passive, muscle. Relative to in vivo …

Maggot Debridement Therapy Vs. Negative Pressure Wound Therapy And Their Effectiveness On Tissue Healing On Older Adults, Angelica L. Funes

Soaring: A Journal of Undergraduate Research

Chronic ulcers, particularly prevalent in older adults, significantly impact patients' quality of life, leading to prolonged hospital stays and increased healthcare costs. This study explores the efficacy of two common therapies, Negative Pressure Wound Therapy (NPWT) and Maggot Debridement Therapy (MDT), in promoting tissue healing for chronic ulcers in adults aged 60 and older. A methodical search was conducted using databases such as CINAHL, PubMed, EBSCO, and ProQuest, employing specific search strategies and inclusion/exclusion criteria. Four high-quality Level 1 randomized controlled trials were selected for analysis, comparing NPWT and MDT in various settings. The results indicate that MDT exhibits superior …

Targeting Transitioning Lung Monocytes/Macrophages As Treatment Strategies In Lung Disease Related To Environmental Exposures, Aaron Schwab, Todd A. Wyatt, Grace Moravec, Geoffrey M. Thiele, Amy J. Nelson, Angela Gleason, Oliver Schanze, Michael J. Duryee, Debra J. Romberger, Ted R. Mikuls, Jill A. Poole

Journal Articles: Pulmonary & Critical Care Med

Background: Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) induce recruited,transitioning murine lung monocytes/macrophages, yet their cellular role remains unclear.

Methods: CCR2 RFP⁺ mice were intratracheally instilled with high concentration ODE (25%), LPS (10 μg), or gram-positive peptidoglycan (PGN, 100 μg) for monocyte/macrophage cell-trafficking studies. CCR2 knockout (KO) mice and administration of intravenous clodronate liposomes strategies were employed to reduce circulating monocytes available for lung recruitment following LPS exposure.Lung tissues and bronchoalveolar lavage fluid (BALF) were collected. Pro-inflammatory and/or pro-fibrotic cytokines, chemokines, and lung extracellular matrix mediators were quantitated by ELISA. …

Role Of Computed Tomography In Traumatic Brain Injuries, Rebekah Spott

Medical Imaging Senior Posters

This project explains the role of computed tomography (CT) in assessing traumatic brain injuries (TBI). The major components of the research include various intracranial traumas, penetrating vs. non-penetrating TBIs, symptoms, grades of injury, and treatment options. CT is essential in diagnosing a TBI because it can quickly produce hundreds of images of the brain and skull in slices. CT allows radiologists, physicians, and surgeons to plan a course of action for the best possible patient recovery outcome. Images can identify various lesions and fractures as well as their severity. A TBI can present itself as penetrating or non-penetrating, ultimately determining …

Neonatal Abstinence Signs During Treatment: Trajectory, Resurgence And Heterogeneity, Jennifer S. Miller, Henrietta S. Bada, Philip M. Westgate, Thitinart Sithisarn, Markos Leggas

Pediatrics Faculty Publications

Neonatal abstinence syndrome (NAS) presents with a varying severity of withdrawal signs and length of treatment (LOT). We examined the course and relevance of each of the NAS withdrawal signs during treatment in a sample of 182 infants with any prenatal opioid exposure, gestational age ≥ 35 weeks, without other medical conditions, and meeting the criteria for pharmacological treatment. Infants were monitored using the Finnegan Neonatal Abstinence Scoring Tool. Daily mean Finnegan scores were estimated using linear mixed models with random subject effects to account for repeated withdrawal scores from the same subject. Daily item prevalence was estimated using generalized …

Research Annual Report Fy2024, Children's Mercy Kansas City

Research Annual Reports

Annual report of the research at Children's Mercy Kansas City in Kansas City MO, a pediatric medical center.

Guideline For Management Of Alcohol Withdrawal Syndrome In A Southern California Jail, Tchuisse Hermione

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: In the United States, 52.8% of Americans aged 18 and older consume alcohol, with 29.5 million suffering from alcohol use disorder (AUD). In Los Angeles, 69.8% of Angelinos aged 12 and older suffer from AUD, and 33% of annual arrests are due to alcohol and other drugs. Alcohol withdrawal syndrome (AWS) develops after abrupt cessation of heavy drinking and is a common occurrence among incarcerated people when newly arrested, resulting in $1.3 billion in healthcare costs. Management of AWS using a fixed-dose therapy of benzodiazepines will improve the utilization of healthcare services in the correctional setting.

Objectives: The project …

Individualizing Patient Education To Reduce Heart Failure Readmissions, Melissa M. Andersen

Doctor of Nursing Practice (DNP) Scholarly Projects - Archive

Background: Heart failure (HF) is a chronic condition with high readmission rates, often due to inadequate patient knowledge about home care and symptom management. Individualized patient education combined with standardized approaches could improve patient outcomes.

Objective: This project’s goal was to determine if using individual patient knowledge to create a personalized education along with standard HF education would improve patient HF knowledge, improve home management and decrease HF readmission rates.

Methods: This pilot quality improvement (QI) project was conducted in an acute care hospital using a convenience sample of 29 patients admitted due to a HF exacerbation using pre-posttest design. …

The Effects Of Cannabis Use On Adverse Cardiovascular Outcomes, Mortality, And Cost Of Hospitalization: Retrospective Study Using National Inpatient Sample, Rabab Elsadek, Zeeshan Ismail, Isaac Loseke, Hashim Al-Ani, Mona Fikry, Suzanne Zentko

North Florida Division GME Research Day 2024

No abstract provided.

Non-Invasive Ventilatory Support, Tube Feeding & Risk Of Aspiration Pneumonia, Jason Mae Chacon, Zuhaib Murtaza, Sarah Barraza, Judy Jin, Payal Passi

Central & West Texas GME Research Day 2024

No abstract provided.

Case Study: Post-Traumatic Calcaneonavicular Coalition, Jihae Kim, James Clancy

East Florida Division GME Research Day 2024

No abstract provided.

Performance Improvement Project: Breast Cancer Screening, Manolo Torres, Julia Fashner, Warda Rana, Robert Chua

East Florida Division GME Research Day 2024

No abstract provided.

Ominous Mediastinal Mass Revealing Ectopic Thyroid, Cameron Summers, Gabriella Morey, Susana Ferra

East Florida Division GME Research Day 2024

Introduction: This report describes an asymptomatic 63-year-old female with a right paratracheal mass compressing and displacing the trachea to the left. Additionally, the epidemiology, clinical manifestation, diagnosis, and management of mediastinal ectopic thyroids are discussed.

Case Summary: A 63 y/o female with history of hypertension, myasthenia gravis and Type 2 diabetes mellitus had a hospitalization for pneumonia and was incidentally found via chest CT scan with a right paratracheal soft tissue mass with few coarse calcifications measuring 7.5 cm displacing the trachea to the left without compromise of the lumen. She was referred to a local cardiothoracic surgeon and underwent …

To Have And To Not Hold: Long-Acting Insulin For Npo Patients With Diabetes, William Hicks, Cindy Iwuagwu, Suzan Khalil, Juan Pablo Meruvia Garron, Cynthia Schwartz, Carlos Botero Suarez, Ashwini Komarla, Mustafa Kinaan

North Florida Division GME Research Day 2024

No abstract provided.

Esophageal Foreign Body: A Case Of The Hidden Wire Brush, Rebecca Ashton Taylor, Sandra Scott, William Jones, Jonnalagadda Veeraen

South Atlantic Division GME Research Day 2024

No abstract provided.

Cryptococcus Gattii: Disseminated Disease In An Immunocompetent Patient, Conner Dalton, Jani Smit

South Atlantic Division GME Research Day 2024

No abstract provided.

Facial Angiosarcoma Masquerading As Rosacea, Rachel Murray, Danielle Glinka, Juan Rosario-Collazo, Karthik Krishnamurthy

South Atlantic Division GME Research Day 2024

No abstract provided.

Drug Reaction With Eosinophilia And Systemic Symptoms (Dress) Syndrome: Lamotrigine Associated, Kendal Allen, Jordan Steelquist, Renee Delos Angeles, He Wang, Andrew Chen

Far West Division GME Research Day 2024

No abstract provided.

Stop Horsing Around: A Case Of Cenbuterol Toxicity, Justin Sanchez, Mark Cheneler, Alexandra Villacres

North Texas GME Research Forum 2024

Introduction: Clenbuterol is a medication that is relatively unknown outside of the equestrian and bodybuilding worlds. It acts as a sympathomimetic compound with beta-2 agonism and can cause tachycardia and bronchodilation. It is utilized for this bronchodilation as a means of improving equestrian performance. Its sympathomimetic effects were utilized in the bodybuilding community as a weight loss medication by increasing catabolic metabolism. Here we present a case of intentional clenbuterol toxicity for weight loss. Case presentation: A 34-year-old woman with past medical history of migraines presented to the emergency department for evaluation of palpitations and an EKG showed sinus …

Improving Documentation Of Patients' Physical Activity In The Outpatient Setting, Jordan Price, Syed Abbas, William Bass, Rigoberto Hernandez, Abdullah Shuaib, Michele L. Mccarroll, Lindsay Porter

North Texas GME Research Forum 2024

Background: There is vast data on the health benefits of physical activity (PA) and the serious health consequences that are associated with a sedentary lifestyle. Research suggests that physicians who have meaningful conversations about exercise with their patients can be effective at increasing their patients' PA. In order to measure the effects of these discussions, the clinician must be able to document the baseline and subsequent PA of their patients. Our project seeks to improve the assessment and documentation of patient PA. Methods: Using Plan-Do-Study-Act (PDSA) quality improvement methodology, a multidisciplinary team was created to identify ways to improve documentation …

Intertwin Membrane Separation In Monochorionic- Diamniotic Twins, Fran Franceschini Lopez, N Moreno, Henry Garcia, Manuel Rivera-Alsina

Central & West Texas GME Research Day 2024

No abstract provided.

Retrospective Study: Adverse Effects Of Hyperglycemia In Nondiabetic Critically Ill Patients With Myocardial Infarction, Enkhbileg Batbileg, Jourdan Harper, Daniel Moore, Carol Wang, Sarah Barraza

Central & West Texas GME Research Day 2024

No abstract provided.

Case Report: A 28-Year-Old Male With Bilateral Lower Extremities Paresthesias, Characteristic Presentation Of Guillain-Barre Syndrome And Innovative Treatments, Petros Keoseyan, Ricky Oshakuade, Danielle Genov, Derek Draper, Nick Duff, Anna Belits, Dmitriy Scherbak

Continental, MidAmerica, & Mountain Divisions GME Research Day 2024

No abstract provided.

Duodenal Ulcer Complicated By Pneumobilia After Chronic Use Of Prednisone, Mihran Ogaryan, Sandra Abadir, Ariel Ahl, Muhammad Durrani, Nusayba Ahmed, Kumar Desai

Far West Division GME Research Day 2024

No abstract provided.

Tracheal Bleed With A Laryngectomy From An Innominate Artery Fistula, Cherry Liu, James West, Hunter Brooks, Jennifer Gilbert, Gabe Scally, Sara Hajizadeh Barfjani, Siddharth Singh

Far West Division GME Research Day 2024

No abstract provided.

Left Bundle Branch Block After Moderna Covid-19 Booster, Yamann Sahlool, Neil Gerts, Yann Dacquay, Mihran Ogaryan, Saro Avedikian, Jeong Hwan Kim, Vishva Dev, Jasprit Takher

Far West Division GME Research Day 2024

No abstract provided.

Decreasing Blood Culture Contamination At A Children’S Hospital, Taylor Pearl, Brittany Bare, Ricardo Zegarra-Linares, Jessica Lee

South Atlantic Division GME Research Day 2024

No abstract provided.