Medical Specialties Commons^™

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Neuropsychological Sequelae Of Brain Tumors, John L. Fisk, Jerel E. Del Dotto

Henry Ford Hospital Medical Journal

Investigation of the neuropsychological sequelae of brain tumors is extremely complex largely because the neurobehavioral consequences of brain tumors depend upon complex interactions among disease and treatment variables as well as patient characteristics. To illustrate some of these complexities, we present case studies of two patients in whom the behavioral outcome was not easily predictable on the basis of our current understanding of brain-behavior relationships in tumor patients. The case studies do illustrate how neuropsychological evaluation aids in identifying cognitive deficits which have implications for subsequent quality of life. Recommendations for future experiments and statistical analyses of neurobehavioral data of …

Health And Adjustment In Young Adults: Preliminary Findings From An Epidemiologic Survey, Naomi Breslau, Glenn C. Davis, Patricia Andreski

Henry Ford Hospital Medical Journal

No abstract provided.

Response To Cpap And Uppp In Apnea, Frank J. Zorick, Timothy Roehrs, William Conway, George Potts, Thomas Roth

Henry Ford Hospital Medical Journal

Ninety-two consecutive patients with obstructive sleep apnea syndrome (OSAS) were studied before and six weeks after treatment with either nasal continuous positive airway pressure (CPAP) or uvulopalatopharyngoplasty (UPPP) (n = 46 per group). Assignment of patients to treatment was based on clinical considerations and patient preference. Patients were assessed by nocturnal polysomnography and performance on the Multiple Sleep Latency Test (MSLT) the following day. Before treatment, the CPAP and UPPP groups did not differ in sleep-related respiratory disturbance, oxygenation during sleep, fragmentation of sleep, or the level of excessive daytime sleepiness indicated by the MSLT. Both treatments produced significant improvement …

Perioperative Management Of Diabetes, Gary W. Edelson, J. David Fachnie, Fred W. Whitehouse

Henry Ford Hospital Medical Journal

No abstract provided.

The Physiologic Basis For Nutritional Support In Hepatic Failure, John J. Fath

Henry Ford Hospital Medical Journal

Hepatic failure is often perceived as a unidimensional progression from near normal clinical function (Child's class A) to overt clinical failure (Child's class C). As this view fails to distinguish between patients who are capable of using exogenous protein and those who cannot, it hinders the nutritional support team in determining protein supplementation. This report addresses the physiologic basis for variable findings in hepatic failure and proposes a simple definition of hepatic faliure based upon ability to utilize amino acids.

Nutritional Implications Of Liver Transplantation, Jeanette M. Hasse

Henry Ford Hospital Medical Journal

Malnutrition is a common problem of patients undergoing liver transplantation. To treat malnutrition, it must first be identified through a nutritional assessment. Because many objective nutritional assessment parameters have limitations in end-stage liver disease, subjective nutritional indicators may be used as an alternative. Nutritional needs following transplantation are categorized as short and long term. The short-term nutritional goal, anabolism, can be complicated by the nutritional status of the patient, surgical procedures, and necessary medications. The increased nutrient needs during the early posttransplant phase require particular nutritional support. Nutrition-related problems following transplantation may include obesity, hyperlipidemia. hypertension, diabetes mellitus. hyperkalemia, edema, …

Allogeneic Whole Pancreas Transplantation In Insulin-Dependent Diabetes Mellitus, José Goldman, Heung K. Oh, Mark G. Webb, Martin Mozes, Nancy Turza, Warren L. Kupin, K. K. Venkat, Ramón Del Busto

Henry Ford Hospital Medical Journal

A clinical whole organ pancreas transplantation program for patients with insulin-dependent diabetes mellitus complicated by end-stage renal disease was initiated at Henry Ford Hospital in 1987. Five patients have received pancreatic allografts after a previous kidney transplant (phase 1), and six patients had simultaneous pancreas-kidney transplants (phase 2). Ten patients had functioning pancreatic grafts after surgery, and all of them had normal carbohydrate tolerance with appropriate plasma free insulin responses to an oral glucose tolerance test three months after transplantation. As long as 28 months postsurgery six patients remained free of insulin requirements; however, one patient rejected the pancreatic allograft, …

Passive Inhalation Of Cocaine By Infants, Sabrina M. Heidemann, Mark G. Goetting

Henry Ford Hospital Medical Journal

Cocaine abuse has increased greatly in recent years, creating important medical, legal, and social problems. Urine drug testing is used to diagnose cocaine ingestion. The presence of the cocaine metabolite benzoylecgonine (BZ) is commonly believed to be proof of recent cocaine intoxication. However, oral ingestion of even a minute quantity of cocaine can result in a positive test result. BZ was detected in the urine of four nonbreast-fed infants aged 6 weeks to 14 months who were admitted with diagnoses unrelated to cocaine poisoning. These infants were exposed to cocaine by passive inhalation of vapors generated by adult caretakers smoking …

Psychiatry Update: Current Research And Other New Developments, Glenn C. Davis, Naomi Breslau

Henry Ford Hospital Medical Journal

No abstract provided.

Effects Of Age, Neuropsychological Impairment, And Medication On Regional Cerebral Blood Flow In Schizophrenia And Major Affective Disorder, Perry C. Goldstein, Gregory G. Brown, Andrew Marcus, James R. Ewing

Henry Ford Hospital Medical Journal

Reports of abnormalities of regional cerebral blood flow (rCBF) in patients with schizophrenia and major affective disorder are contradictory. To gain a better understanding of the possible sources of these contradictions, the rCBF and neuropsychological functioning of 15 schizophrenics, 15 patients with major affective disorder, and 15 age-matched controls were studied. No group differences in overall rCBF, percent frontal devialion in flow, or rCBF asymmetries were observed. Both overall rCBF and percent frontal deviation of rCBF were reduced with greater age and with increasing neuropsychological impairment. Dosage of neuroleptic medication was associated with reduced whole brain flow, not with percent …

The Ketterer Stress Symptom Frequency Checklist: Anger And The Severity Of Coronary Artery Disease, Mark W. Ketterer

Henry Ford Hospital Medical Journal

Recent research suggests that the most potent feature of the Type A behavior pattern for prospectively predicting cardiac disease is aggravation, irritation, anger, and impatience (AIAI). The present study examines psychometric properties of a new AIAI measure and its relationship to the severity of coronary artery disease (CAD). Subjects included 61 males undergoing coronary angiography. Comparisons were made of mean psychometric scores across groupings, defined by number of vessels occluded. These comparisons showed that the normal or subclinically occluded coronary angiographic group had high levels of depression and anxiety. Higher levels of AIAI were observed in patients with multivessel CAD …

Psychometric Profiles Of Patient Populations With Excessive Daytime Sleepiness, Edward J. Stepanski, Jon J. Markey, Frank J. Zorick, Thomas Roth

Henry Ford Hospital Medical Journal

Patients with narcolepsy have more psychiatric symptoms than normal controls as measured by psychometric tests. However, it is unclear whether these findings are specific to narcolepsy, as some studies have suggested, or related to excessive daytime sleepiness (EDS) or to chronic illness. We compared a group of 56 narcoleptics to age- and sex-matched controls with EDS. A group of 48 individuals with normal sleep architecture was also used as an additional control group. Both the narcoleptic group and the EDS-control group had significantly greater scores on Minnesota Multiphasic Personality Inventory scales hut were not different from each other. Our data …

From His Rib, J. David Fachnie

Henry Ford Hospital Medical Journal

No abstract provided.

An Overview Of Renal Transplantation At Henry Ford Hospital, Warren L. Kupin, K. K. Venkat, Martin Mozes, Hajime Hayashi, Heung K. Oh

Henry Ford Hospital Medical Journal

No abstract provided.

Rectal Non-Hodgkin's Lymphoma: A Clinicopathologic Study And Review, Cary A. Gottlieb, Eyal Meiri, Koichi Maeda

Henry Ford Hospital Medical Journal

A total of 11 patients with lymphomatous involvement of the rectum were seen at Henry Ford Hospital between 1964 and 1987. Eight of these patients had primary rectal lymphoma and three had secondary rectal lymphoma. These patients' clinical presentation and course as well as pathological findings are described and compared with cases previously reported. As identified in ours and others' series, rectal lymphomas are associated with the acquired immunodeficiency syndrome and tend to have a B-cell phenotype.

Lipohyperplasia Of Ileocecal Valve, Causing Recurrent Intussusception, Lacey Walke, Adrian J. Christie

Henry Ford Hospital Medical Journal

Lipohyperplasia of the ileocecal valve is a fairly common entity that occasionally behaves as an intestinal tumor, causing obstruction, sometimes with intussusception, or bleeding, which may be acute or chronic. Most often occurring in middle-aged or elderly women, it may be mistaken clinically and radiologically for carcinoma or other neoplasms. Its differentiation is best made by endoscopy, confirmed if possible by biopsy. Differentiation is important, as the treatment is a limited ileal and cecal resection, instead of a blind hemicolectomy. A recent study suggests possible associations with other medical conditions. We describe the clinical and pathological findings of this entity …

The Smoke-Out At Henry Ford Hospital, Or How Henry Ford Created A Smoke-Free Environment, Sidney Goldstein

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, December 1990, Boonshoft School Of Medicine

Vital Signs

A fifteen page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Malignant External Otitis And Mastoiditis Associated With An Igg4 Subclass Deficiency In A Child., Ricardo Castro, Md, Norman Robinson, Md, Joel Klein, Md, William Geimeier, Md

Department of Pediatrics Faculty Papers

We have presented the first child in Delaware with malignant external otitis associated with IgG4 deficiency. Our patient needed three courses of intravenous antibiotics and twice required mastoidectomy, but has recovered completely following the restoration of the natural barrier between the internal and external ear, using a fascial graft from the large temporalis muscle. Some hearing deficit remains.

New England Osteopathic Assembly: Kirmes To Bochman 1990-11-5, William Kirmes D.O.

William Kirmes, D.O. Collection

A letter from Dr. Kirmes to Dr. Bruce Bochman in response to his letter welcoming Dr. Kirmes to the New England Osteopathic Assembly board, contacts from UNECOM, and work on special projects.

New England Osteopathic Assembly: Suske To Bochman 1990-10-15, Chester Suske D.O.

William Kirmes, D.O. Collection

A letter from Dr. Chet Suske to Dr. Bruce Bochman regarding the planning of future New England Osteopathic Assembly meetings and the incorporation of UNECOM into the programming.

Platelet A-Granule Fibrinogen, Albumin, And Immunoglobulin G Are Not Synthesized By Rat And Mouse Megakaryocytes, Prem Handagama, Daniel A. Rappolee, Zena Werb, Jack Levin, Dorothy F. Bainton

Department of Obstetrics and Gynecology Research Publications

It has been assumed that endogenous synthesis by the platelet precursor cell, the bone marrow megakaryocyte, is the major source of platelet a-granule protein. To test this hypothesis, we used mRNA phenotyping to detect in megakaryocytes the presence of mRNA transcripts specific for various proteins. Our results indicate that megakaryocytes synthesize platelet factor 4, a protein relatively specific for platelets, but do not express mRNA transcripts for the fibrinogen, albumin, or IgG found in a-granules. We have previously shown that mega- karyocytes endocytose circulating proteins, including fibrino- gen, albumin, and IgG, and incorporate them into a-granules. Thus, platelets appear to …

The Report Of The American Heart Association Task Force On Strategies To Increase Federal Research Funding, Michael R. Rosen, Harold C. Strauss, Holly G. Atkinson, Alfred P. Fishman, Charles K. Francis, Arnold M. Katz, August M. Watanabe, Francois M. Abboud, Myron L. Weisfeldt, William F. Friedman, Bernadine P. Healy, Scott D. Ballin, Claudia Louis, Rodman D. Starke, Wallace G. Frasher

Publications and Research

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1990), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1990 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• President’s Perspective
• In the News
• Up, Up and Away
• "This Joyous Gathering of Our Family"
• The College Chancellor, Reminiscing
• New Appointments
• On Campus
• Class Acts
• In Memorium
• Coming Up

In Defense Of Intrauterine Repair Of Cleft Lip., Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.

New Mexico Location List Of Alumni And Former Housestaff, University Of New Mexico Medical Center

University of New Mexico School of Medicine Location Report

No abstract provided.

Correspondence: Unecom: Kirmes To Lenz 1990-8-20, William Kirmes D.O.

William Kirmes, D.O. Collection

A letter from Dr. Kirmes to Dr. Craig Lenz requesting information about the New England Foundation for Osteopathic Medicine for his work with the UNECOM Self-Study Committee.

Quantitative Respirator Fit Testing: Probed Facepiece Versus Probed Cartridge, Sonya Melissa Seward

Community & Environmental Health Theses & Dissertations

This study was performed to determine if there is a quantifiable difference between quantitative fit testing using a probed facepiece and a probed cartridge. Four subjects were tested on four different respirators. The respirators used were MSA & 3M full and half face respirator. Each subject performed each method five times per respirator. The results indicated no correlation between the two fit testing methods overall. However, a moderate correlation was found between the MSA respirators and the two methods. This study found many variables which influence fit testing. These include the type of respirator used (brand and facepiece), the probe …