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Articles 8401 - 8402 of 8402
Full-Text Articles in Microbiology
Some Impurities In Drinking Water, George Weitbrecht
Some Impurities In Drinking Water, George Weitbrecht
Journal of the Minnesota Academy of Science
The more we know about the causes of disease the more we are convinced that many of the ills that flesh is heir to come to us through germs that are transmitted through the air we breath, the water we drink and the food we eat. You are all familiar with the westward march of cholera among men and epizooty among animals. In surgical operations the danger is not from the operation, but from germs which are in the air and which get into the body through the wound, producing surgical fever, etc. Since Lester used the carbolic acid spray …
Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry
Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry
Nebraska Center for Virology: Faculty Publications
Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication but avoid production of infectious virions, we developed “single-cycle” adenovirus (SC-Ad) vectors. Previous work demonstrated that SC-Ads amplify transgene expression 100-fold and produce markedly stronger and more persistent immune responses than RD-Ad vectors …