Kinesiology Commons^™

Neural Epigenetic Changes In Response To Morphine: A Peek Into The Science Of Addiction, Timothy Smartt, Jeffrey Edwards, Addison Smartt

Library/Life Sciences Undergraduate Poster Competition 2024

Introduction

Since the 1990's, the United States has experienced a crisis of opioid addiction and overdose. The effects of opioids on the ventral tegmental area (VTA), the reward center of the brain, are a primary cause of opioid dependence.

New Perspectives On Foot Segment Forces And Joint Kinetics - Integrating Plantar Shear Stresses And Pressures With Multi-Segment Foot Modeling, Dustin A. Bruening, Spencer R. Petersen, Sarah T. Ridge

Faculty Publications

The role of the foot in gait is not well understood, in part due to challenges in capturing and utilizing segmental ground reaction forces. The purposes of this study were to 1) develop methodology to integrate plantar pressure/shear stresses with a multi-segment foot model, and 2) generate and display key normative data from this combined system. Twenty-six young healthy adults walked barefoot (1.3 m/s) across a pressure/shear sensor with markers matching a published 4-segment kinetic foot model. A novel anatomical/geometric masking method was developed that successfully separated regions aligned with model segmentation. This template-based method can be automated and customized …

The Metabolic Effects Of Exercise And A Pre-Exercise Snack During A 30-Hour Fast, Katelynn Hales, Hil'ilei Chan, Landon S. Deru, Jake Moss, Bruce W. Bailey Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2022

As incidence rates of chronic illnesses continue to increase, many pharmacological and lifestyle interventions have been undertaken to pinpoint effective treatment and prevention tools to combat them. One such intervention of recent interest includes the use of fasting. Ketones, a product of fat breakdown, are thought to be a key player in some of the health benefits achieved through fasting. Despite potential benefits, adhering to a fasting regimen can be difficult. While it is generally well-tolerated, some experience negative side effects,² indicating potential issues with long-term adherence. Heilbronn et al. suggest that a small meal on fasting days may be …

Validity Of Ultrasound Imaging For Intrinsic Foot Muscle Cross-Sectional Area Measurements Demonstrated By Strong Agreement With Mri, Dallin C. Swanson, Joshua K. Sponbeck, Derek A. Swanson, Connor D. Stephens, Steven P. Allen, Ulrike H. Mitchell, James D. George, A. Wayne Johnson

Library/Life Sciences Undergraduate Poster Competition 2022

Intrinsic foot muscles maintain foot structural integrity and contribute to functional movement, posture and balance Thus, assessing intrinsic foot muscle size and strength are important One way to assess strength of a muscle is by measuring its cross sectional area ( Magnetic resonance imaging ( and ultrasound ( are two modalities allowing for visualization of these muscle bodies MRI has been shown to accurately image the individual muscles but is costly and time consuming US imaging may provide an alternative that is less costly and more readily available The purpose of this study was to investigate the validity and reproducibility …

Low-Cost Prosthetic Feet For Underserved Populations: A Comparison Of Gait Analysis And Mechanical Stiffness, Kaleigh Renninger, Brevin Banks, Dustin A. Bruening

Library/Life Sciences Undergraduate Poster Competition 2022

• Lower limb loss is an ongoing cause of disability throughout the world.
• Despite advancements in prosthetic technologies, there are numerous underserved populations in need of effective low-cost prosthetic foot options.

The Effects Of Exercise On Inflammatory Biomarkers Over A 36-H Fast, Austin F. Duersch, Bruce W. Bailey, Landon S. Deru, Jacob Coleman, Hunter Chamberlain, Spencer Cleverly

Library/Life Sciences Undergraduate Poster Competition 2022

Diet-induced chronic inflammation has become a popular point of discussion over recent years in lifestyle medicine as studies have uncovered the effects that inflammation markers have on chronic diseases including heart disease, diabetes, and arthritis. Each time we eat, an immune response is stimulated resulting in increased levels of inflammatory biomarkers.1,2 Interventions to help lower inflammation could help promote longevity and decrease risk of chronic diseases. This study assessed the impact of an acute 36h fast with and without exercise at the beginning on inflammatory biomarkers IL-6, C-peptide, GIP, MCP-1, and TNF-alpha.

Validity Of Intrinsic Foot Muscle Size Measured By Ultrasound And Mri, Dallin Swanson

Undergraduate Honors Theses

Intrinsic foot muscles maintain foot structural integrity and contribute to functional movement, posture and balance. Thus, assessing intrinsic foot muscle size and strength are important. Magnetic resonance imaging (MRI) has been shown to accurately image the individual muscles but is costly and time consuming. Ultrasound (US) imaging may provide an alternative that is less costly and more readily available. The purpose of this study was to investigate the validity and reproducibility of US imaging in measuring intrinsic foot muscle size in comparison to MRI. US and MRI were employed to measure the intrinsic foot muscle size involving 35 participants (females …

Milk-Fat Intake And Differences In Abdominal Adiposity And Bmi: Evidence Based On 13,544 Randomly Selected Adults, Klarissa Rae Wilkinson

Theses and Dissertations

The primary objective of this study was to evaluate the relationship between milk-fat intake and obesity, particularly abdominal obesity, in 13,544 U.S. adults. A secondary objective was to determine the extent to which the association was influenced by multiple potential confounding variables. This cross-sectional study used data from the 2011–2016 National Health and Nutrition Examination Survey (NHANES). Level of milk-fat content regularly consumed was the exposure variable. Body mass index (BMI) and sagittal abdominal diameter (SAD), a measure of abdominal obesity, were the outcome variables. SAD correlates strongly with visceral fat, when measured by computed tomography, and has been shown …

The Relationship Between Vascular Endothelial Function Andpeak Exercise Blood Flow, Brady Edward Hanson

Theses and Dissertations

Purpose The vascular endothelium is an influential contributor to vasodilation at rest, yet its role during peak exercise is relatively unknown. The purpose of this study is to determine if exercise leg blood flow during dynamic submaximal and maximal exercise is related to resting vascular endothelial function. Methods Nineteen subjects (aged 23 ± 0.57 yr) completed multiple assessments of vascular endothelial function including passive leg movement (PLM), rapid onset vasodilation, (ROV) and flow-mediated dilation (FMD). Peak muscle blood flow was assessed during single leg knee extension (KE) exercise. Doppler ultrasound of the femoral artery was utilized to assess muscle blood …

The Effect Of Deep Tissue Heating On Skeletal Muscle Pgc1 A Protein Expression During Muscle Atrophy, Kaitlin Abbott, Dr. Allen Percell

Journal of Undergraduate Research

Through this project, we aimed to determine if repeated heat stress is a viable treatment to reduce or slow muscle atrophy in human muscle subjected to disuse. Specifically, I investigated how repeated heat stress affects the expression of PGC1-a, a gene that is an upstream regulator of mitochondrial biogenesis. This protein promotes muscle growth and normally is triggered by environmental factors including the metabolic needs (energy, temperature, stress, etc.) of the muscle. If it could be increased in the muscle, it could potentially lead to the preservation of muscle strength and function in a variety of disease states. These include …

Effect Of Cuff Pressure On Blood Flow During Blood Flow-Restricted Rest And Exercise, Kent Westerberg Crossley

Theses and Dissertations

Purpose: The purpose of this study was to investigate the blood flow/pressure relationship (linear or nonlinear) in the superficial femoral artery when seated, as well as to investigate blood flow changes with exercise using varying cuff pressures and a preexercise (PE) condition. The presence of venous outflow with occlusion at rest and exercise was also investigated.Methods: Twenty-three subjects visited the lab on 3 occasions. First to determine linearity of blood flow using 0% to 90% arterial occlusion pressure (AOP), and venous outflow at rest and during exercise with cuff inflated to 40% AOP. Subsequent visits compared blood flow between rest …

The Role Of The Midfoot In Drop Landings, Mark T. Olsen, Dustin A. Bruening, A. Wayne Johnson, Sarah T. Ridge

Faculty Publications

Purpose: The midfoot is instrumental to foot function; however, quantifying its roles in human movement has been difficult. A forceful dynamic activity like landing may help elucidate the midfoot’s contribution to foot energetics and function. The main purpose of this study was to measure midtarsal joint kinematics and kinetics during a barefoot single-leg landing task. A secondary aim of this study was to explore the relationship between static foot posture and dynamic midfoot function.

Methods: In a cross-sectional study design, 48 females (age = 20.4 ± 1.8 yr, body mass index = 21.6 ± 1.7 kg/m) performed drop landings from …

A Sport-Specific Wearable Jump Monitor For Figure Skating, Dustin A. Bruening, Riley E. Reynolds, Chris W. Adair, Peter Zapalo, Sarah T. Ridge

Faculty Publications

Advancements in wearable technology have facilitated performance monitoring in a number of sports. Figure skating may also benefit from this technology, but the inherent movements present some unique challenges. The purpose of this study was to evaluate the feasibility of using an inertial measurement unit (IMU) to monitor three aspects of figure skating jumping performance: jump count, jump height, and rotation speed. Seven competitive figure skaters, outfitted with a waist-mounted IMU, performed a total of 59 isolated multi-revolution jumps and their competition routines, which consisted of 41 multi-revolution jumps along with spins, footwork, and other skills. The isolated jumps were …

The Effect Of Repeated Heat Stress On Mitochondrial Protein Content In Human Skeletal Muscle, Amy Twitchell, Robert Hyldahl

Journal of Undergraduate Research

Exercise has been known to improve mitochondrial function and increase its content in muscle. However, those who suffer from certain diseases such as Chronic Obstructive Pulmonary Disease (COPD) and Type II Diabetes often experience concomitant exercise intolerance. In vitro research suggests that the application of a mild heat stress may be sufficient to activate some of the same signaling proteins that become active during exercise, possibly leading to mitochondrial biogenesis in skeletal muscle. However, this has not yet been confirmed to occur in human skeletal muscle. Therefore, the purpose of this study was to investigate the effect of heat therapy …

The Effects Of Ice And Tens Combination Treatment On Knee And Hip Joint Neuromechanics In Individuals With Experimentally Induced Knee Pain During Running, Sunku Kwon

Theses and Dissertations

Context: Knee injury is a common problem for runners. Knee pain is a common symptom in knee injury and is associated with alterations in knee and hip muscle activation and hip joint angles. Relieving pain through intervention may help to restore neuromuscular function. Objective: To examine the effects of ice and transcutaneous electrical nerve stimulation (TENS) combination treatment on perceived knee pain, hip frontal plane angle, and muscle activation during running in individuals with experimental knee pain (EKP). Design: Crossover. Setting: Laboratory. Subjects: 19 participants (11 males and 8 females, 23.2 ± 1.9 y, 176 …

Effect Of Restricted Ankle Mobility On Muscle Reaction Time And Ankle Joint Kinematics To A Simulated Ankle Sprain During Walking In Chronic Ankle Instability Patients, Brandon Winward, Ty Hopkins

Journal of Undergraduate Research

Inversion ankle sprains are common and are caused by sudden inversion stresses during weight-bearing movement which causes the foot to roll under and inward.1 Ankle sprains result in tearing or stretching of ligaments and muscles, which reduces ankle stability.2 After a single ankle sprain, up to 80% of people suffer repeated sprains, which often develop into chronic ankle instability (CAI).3 Research has shown CAI patients often exhibit delayed lower leg muscle reaction time and restricted dorsiflexion range of motion (DROM).2

Passive Hallux Adduction Decreases Blood Flow To Plantar Fascia, Julia Lorene Dunbar

Theses and Dissertations

Purpose: Due to the vital role that blood flow plays in maintaining tissue health, compromised blood flow can prevent effective tissue healing. An adducted hallux, as often seen inside a narrow shoe, may put passive tension on the abductor hallucis, consequently compressing the lateral plantar artery (LPA) into the calcaneus and thus restricting blood flow. The purpose of this study was to compare blood flow within the LPA before and after passive hallux adduction (PHA). Methods: Forty-five healthy volunteers (20 female, 25 male; age = 24.8 ± 6.8 yr; height = 1.7 ± 0.1 m; weight = 73.4 ± 13.5 …

Gait Alterations And Plantar Pressure In Diabetic Peripheral Neuropathy: A Preliminary Study, Adrienne Dora Henderson

Theses and Dissertations

Background: Despite a lack of consensus on its utility, clinicians have traditionally relied on plantar pressure (PP) to predict ulcer risk and prescribe interventions in individuals with diabetic peripheral neuropathy (DPN). Joint kinematics and kinetics have the potential to contribute to DPN assessment and treatment, however previous studies have not accounted for walking speed nor integrated a full-body analysis with a detailed foot model. Purpose: To assess PP and gait alterations in DPN by controlling walking speed and incorporating a multisegment foot model into a full-body gait analysis. We hypothesize that hip and ankle kinetics will be altered consistent with …

Control Of Redundant Pointing Movements Involving The Wrist And Forearm, Garrett R. Dorman, Kevin C. Davis, Allan W. Peaden, Steven K. Charles

Faculty Publications

The musculoskeletal system can move in more ways than are strictly necessary, allowing many tasks to be accomplished with a variety of limb configurations. Why some configurations are preferred has been a focus of motor control research, but most studies have focused on shoulder-elbow or whole-arm movements. This study focuses on movements involving forearm pronation-supination (PS), wrist flexion-extension (FE), and wrist radial-ulnar deviation (RUD), and elucidates how these three degrees of freedom (DOF) combine to perform the common task of pointing, which only requires two DOF. Although pointing is more sensitive to FE and RUD than to PS and could …

Dysregulation Of Tenascin C And Hyaluronic Acid In Aged Skeletal Muscle, Alex Holland, Alan Parcel

Journal of Undergraduate Research

Satellite cells are the progenitor stem cells of skeletal muscle (SM) that reside between the sarcolemma and basal lamina. This space is referred to as the satellite cell niche. Following injury, quiescent satellite cells are activated, proliferate then migrate and fuse to the injured region of muscle to support regeneration (3). Satellite cells in muscle tissue from older subjects migrate at less than half the speed of those in young tissue (2). This may contribute to the diminished regenerative response observed in older subjects. Tenascin C (TNC) has been identified as a de-adhesion protein that is upregulated in the satellite …

The Effect Of Photobiomodulation Therapy On Exercise-Induced Muscle Damage, Kathleen Nichole Thiriot

Theses and Dissertations

Purpose: To explore the difference between continuous and pulsed photobiomodulation (PBMT) versus a placebo treatment when using a red-blue light combination over multiple treatment sessions to decrease the symptoms of muscle damage in the quadriceps muscle after a bout of muscle damaging exercise. Methods: Thirty-six healthy, nonactive male and female participants were randomly assigned to one of three groups: continuous PBMT, pulsed PBMT, and placebo treatment. Participants were assessed for muscle damage with knee extension maximal isometric and isokinetic contractions, as well as Visual Analog Scale (VAS) and Lower Extremity Functional Scale (LEFS) scores. Blood creatine kinase (CK) was also …

The Effects Of A Three-Hour, After School Bout Of Sedentary Vs Active Behavior On Reward And Cognitive Control Activation In 8- To 9-Year-Old Children: A Randomized Crossover Study, Mary Linn White

Theses and Dissertations

PURPOSE: To compare the effects of after-school sedentary versus active play on activation in the reward and cognitive control regions of the brain to pictures of high- and low-calorie foods. METHODS: 32 children (12 girls, 20 boys; age 8.7 ± 0.5 years; height 137.9 ± 6.9 cm; weight 32.4 ± 6.2 kg) participated in a randomized crossover study with counterbalanced treatment conditions. Conditions took place on separate days after school and included three hours of active or sedentary play. After each condition, neural activation in reward and cognitive control regions of the brain were assessed using functional magnetic resonance imaging …

Effects Of Ice Massage Prior To An Iontophoresis Treatment Using Dexamethasone, Brady Michael Smith

Theses and Dissertations

Context: Low current intensity iontophoresis treatments have shown an increase in skin perfusion over 700% from baseline potentially increasing drug clearance from the targeted area. Objective: To determine the effects of a 10-minute ice massage on subcutaneous dexamethasone sodium phosphate (Dex-P) concentration and skin perfusion during and after a 4 mA iontophoresis treatment. Design: Controlled laboratory study. Setting: Research Laboratory. Patients or Other Participants: 26 individual participants (Males = 15, Females = 11, age = 25.6 ± 4.5 y, height = 173.9 ± 8.51 cm, mass = 76.11 ± 16.84 kg). Interventions: Participants were randomly assigned into two groups: 1) …

Positional Release Therapy Versus Therapeutic Massage In Reducing Muscle Trigger And Tender Points, Amber Hancock Bethers

Theses and Dissertations

Objective: To determine the difference in effectiveness of positional release therapy (PRT) compared with therapeutic massage (TM) in treating trigger and tender points in the upper trapezius muscle. Background: Trigger points in the upper trapezius muscle are common and can be painful. Therapeutic massage is a more traditional treatment method for this condition while PRT is relatively new. Design and Setting: A randomized-group design was used to examine the differences between the 2 treatments for reducing pain and muscle tension. Subjects: Sixty healthy subjects (males = 24, females = 36; age = 27.1 ± 8.8 years; wt = 75.2 ± …

The Effect Of Whole-Body Vibration In Repositioning The Talus In Chronic Ankle Instability Populations, Melissa Nicole Frixione

Theses and Dissertations

Context: Dorsiflexion range of motion (DFROM) is often limited in patients with chronic ankle instability (CAI). Whole-body vibration (WBV) may enhance DFROM by helping to reposition the talus and assisting with talocrural arthrokinematics. Objective: To determine if WBV can enhance DFROM in patients with ankle instability and determine if talar position is affected. Setting: Cohort study. Patients or Other Participants: A total of 25 subjects with CAI (17 women, 8 men; age = 22 ±2.101 years, mass = 72.4 ±17.9 kg, height = 171.2 ± 11.6 cm) participated. Intervention(s): Participants in the WBV group completed a 4-week (12 session) WBV …

Positional Release Therapy Versus Therapeutic Massage In Reducing Muscle Trigger And Tender Points, Amber Hancock Bethers

Theses and Dissertations

Objective: To determine the difference in effectiveness of positional release therapy (PRT) compared with therapeutic massage (TM) in treating trigger and tender points in the upper trapezius muscle. Background: Trigger points in the upper trapezius muscle are common and can be painful. Therapeutic massage is a more traditional treatment method for this condition while PRT is relatively new. Design and Setting: A randomized-group design was used to examine the differences between the 2 treatments for reducing pain and muscle tension. Subjects: Sixty healthy subjects (males = 24, females = 36; age = 27.1 ± 8.8 years; wt = 75.2 ± …

Can A Preseason Screen Predict Injury Or Performance Over Three Years Of College Football?, Bartley B. Mortensen

Theses and Dissertations

Purpose: To investigate if the Functional Movement Screen (FMSâ„¢) total score, individual component test scores or number of asymmetries can predict noncontact injury risk or player performance over three consecutive seasons of NCAA Division I football. Methods: As football teams are comprised of individuals with vastly different physical characteristics and playing responsibilities, we divided the subjects into three homogeneous groups based on position (Big, Combo and Skill). Each FMSâ„¢ score was assessed with regard to the total team score as well as by individual position groups. For our injury analysis we also controlled for exposure. For player performance we controlled …

The Role Of The Midfoot In Drop Landings, Mark Taylor Olsen

Theses and Dissertations

The contribution of the midfoot in landing mechanics is understudied. Therefore, the main purpose of this study was to quantify midtarsal joint kinematics and kinetics during a barefoot single-leg landing task. A secondary aim of this study was to explore the relationship between static foot posture and dynamic midfoot function. In a cross-sectional study design, 48 females (age = 20.4 ± 1.8 yr, height = 1.6 ± 0.06 m, weight = 57.3 ± 5.5 kg, BMI = 21.6 ± 1.7 kg·m^-1) performed drop landings from a height of 0.4 m onto split force platforms. Subjects hung from wooden …

Walking In Minimalist Shoes Is Effective For Strengthening Foot Muscles, Sarah T. Ridge, Mark T. Olsen, Dustin A. Bruening, Kevin Jurgensmeier, David Griffin, Irene S. Davis, A. Wayne Johnson

Faculty Publications

Introduction: Weakness of foot muscles may contribute to a variety of loading-related injuries. Supportive footwear may contribute to intrinsic foot muscle weakness by reducing the muscles’ role in locomotion (e.g., absorbing forces and controlling motion). Increased stimulus to the foot muscles can be provided through a variety of mechanisms, including minimalist footwear and directed exercise.

Purpose: To determine the effect of walking in minimalist footwear or performing foot strengthening exercises on foot muscle size and strength.

Methods: Fifty-seven runners were randomly assigned to one of three groups—minimalist shoe walking (MSW), foot strengthening (FS) exercise, or control (C). All groups maintained …

Comparison Of Varying Heel To Toe Differences And Cushion To Barefoot Running In Novice Minimalist Runners, Danny Moody, Iain Hunter, Sarah T. Ridge, J. William Myrer

Faculty Publications

There are many different types of footwear available for runners in today’s market. Many of these shoes claim to help runners run more efficiently by altering an individual’s stride mechanics. Minimalist footwear claims to aid runners run more on their forefeet whereas more traditional footwear provides more cushioning specifically for a heel first landing. The purpose of this paper was to determine if runners, who were accustomed to running in traditional footwear would alter their running mechanics while running acutely in various types of minimalist footwear. Twelve subjects, accustomed to running in traditional 12 mm heel/toe differential footwear, ran in …