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Label-Free Biochemical Recognition Using Mems Resonators For Microarray Technology, Babak Tousifar 2011 University of Denver

Label-Free Biochemical Recognition Using Mems Resonators For Microarray Technology, Babak Tousifar

Electronic Theses and Dissertations

Highly sensitive biosensors capable of detecting and characterizing smallest quantities of cellular and molecular targets are needed in pharmaceutical and medical diagnostics industries. In this work, the importance of biological target recognition specifically proteins through microarray technologies has been discussed and the most successful tools and techniques have been studied. Moreover, a thermally actuated Micro Electro-Mechanical Systems (MEMS) resonator has been demonstrated and fabricated in this work as an accurate, reliable and low cost biotechnology tool. As a proof of concept, amine to epoxide coupling of octadecylamine to functionalized silicon dioxide surface have been shown through resonator frequency monitoring. The …


Computational Prediction Of The Influence Of Crosslink Distribution On The Thermo-Mechanical Properties Of Epoxies, Ananyo Bandyopadhyay 2011 Michigan Technological University

Computational Prediction Of The Influence Of Crosslink Distribution On The Thermo-Mechanical Properties Of Epoxies, Ananyo Bandyopadhyay

Dissertations, Master's Theses and Master's Reports - Open

Experimental studies on epoxies report that the microstructure consists of highly crosslinked localized regions connected with a dispersed phase of low crosslink density. The various thermo-mechanical properties of epoxies might be affected by the crosslink distribution. But as experiments cannot report the exact number of crosslinked covalent bonds present in the structure, molecular dynamics is thus being used in this work to determine the influence of crosslink distribution on thermo-mechanical properties. Molecular dynamics and molecular mechanics simulations are used to establish wellequilibrated molecular models of EPON 862-DETDA epoxy system with a range of crosslink densities and various crosslink distributions. Crosslink …


In-Situ Electrical, Mechanical And Electrochemical Characterizations Of One-Dimensional Nanostructures, Hessam Mir Shah Ghassemi 2011 Michigan Technological University

In-Situ Electrical, Mechanical And Electrochemical Characterizations Of One-Dimensional Nanostructures, Hessam Mir Shah Ghassemi

Dissertations, Master's Theses and Master's Reports - Open

One-dimensional nanostructures initiated new aspects to the materials applications due to their superior properties compared to the bulk materials. Properties of nanostructures have been characterized by many techniques and used for various device applications. However, simultaneous correlation between the physical and structural properties of these nanomaterials has not been widely investigated. Therefore, it is necessary to perform in-situ study on the physical and structural properties of nanomaterials to understand their relation. In this work, we will use a unique instrument to perform real time atomic force microscopy (AFM) and scanning tunneling microscopy (STM) of nanomaterials inside a transmission electron microscopy …


Computational Simulations Of Latent Heat Thermal Energy Storage Systems - With Innovative And First-Principles Based Simulation For The Underlying Unsteady Melting (And Solidification) Processes, Rohan Achyut Gumaste 2011 Michigan Technological University

Computational Simulations Of Latent Heat Thermal Energy Storage Systems - With Innovative And First-Principles Based Simulation For The Underlying Unsteady Melting (And Solidification) Processes, Rohan Achyut Gumaste

Dissertations, Master's Theses and Master's Reports - Open

This thesis develops an effective modeling and simulation procedure for a specific thermal energy storage system commonly used and recommended for various applications (such as an auxiliary energy storage system for solar heating based Rankine cycle power plant). This thermal energy storage system transfers heat from a hot fluid (termed as heat transfer fluid - HTF) flowing in a tube to the surrounding phase change material (PCM). Through unsteady melting or freezing process, the PCM absorbs or releases thermal energy in the form of latent heat. Both scientific and engineering information is obtained by the proposed first-principle based modeling and …


Development Of A Continuum Mechanics Model Of Passive Skeletal Muscle, Duane A. Morrow 2011 Michigan Technological University

Development Of A Continuum Mechanics Model Of Passive Skeletal Muscle, Duane A. Morrow

Dissertations, Master's Theses and Master's Reports - Open

Skeletal muscle force evaluation is difficult to implement in a clinical setting. Muscle force is typically assessed through either manual muscle testing, isokinetic/isometric dynamometry, or electromyography (EMG). Manual muscle testing is a subjective evaluation of a patient’s ability to move voluntarily against gravity and to resist force applied by an examiner. Muscle testing using dynamometers adds accuracy by quantifying functional mechanical output of a limb. However, like manual muscle testing, dynamometry only provides estimates of the joint moment. EMG quantifies neuromuscular activation signals of individual muscles, and is used to infer muscle function. Despite the abundance of work performed to …


Analytical And Experimental Vibration Analysis Of Variable Update Rate Waveform Generation, Joshua F. Mark 2011 Wright State University

Analytical And Experimental Vibration Analysis Of Variable Update Rate Waveform Generation, Joshua F. Mark

Browse all Theses and Dissertations

Typical vibration analysis of turbine engine components incorporates the use of a function generator to produce a signal that is routed to an excitation source as the forcing function of the test specimen. These waveforms are constructed by varying the amplitude of the signal over time with a fixed update rate (time increment between samples). This research investigates generating chirp waveforms by storing only one sinusoid of points and using an external timing signal to repetitively send out these stored data points. This results in varying the amplitude of the signal over time as well as the update rate. The …


Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu T. Tekalign, Margo S. Levine 2011 Western Kentucky University

Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu T. Tekalign, Margo S. Levine

Mathematics Faculty Publications

The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.


Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu Tekalign, Margo Levine 2011 Western Kentucky University

Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu Tekalign, Margo Levine

Mathematics Faculty Publications

The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.


An Integrated Platform To Increase The Range/Endurance Of Unmanned Helicopters, Roy Godzdanker 2011 University of Denver

An Integrated Platform To Increase The Range/Endurance Of Unmanned Helicopters, Roy Godzdanker

Electronic Theses and Dissertations

Class I (kg) autonomous helicopters are becoming increasingly popular for a wide range of non-military applications such as, surveillance, reconnaissance, traffic monitoring, emergency response, agricultural spraying, and many other "eye in the sky" missions. However, an efficient landing/takeoff platform with refueling/recharging capabilities has not yet been developed to increase the endurance and decrease the cost for Class I helicopters.

This dissertation presents a three-prong approach for increasing the range and endurance of Class I autonomous helicopters, which will then spur demand by non-military organizations wanting to take advantage of such capabilities and, therefore, drop their price. The proposed Intelligent Self-Leveling …


Test 2012a: New Holland Workmaster 55, Nebraska Tractor Test Lab 2011 University of Nebraska-Lincoln

Test 2012a: New Holland Workmaster 55, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …


Probabilistic Stress Analysis Of Circular Fins Of Different Profiles, Sridhar Madhira venkata 2011 Cleveland State University

Probabilistic Stress Analysis Of Circular Fins Of Different Profiles, Sridhar Madhira Venkata

ETD Archive

The temperature distribution and thermal Stresses induced by a temperature difference for steady state heat transfer in silicon carbide (SiC) ceramic tube heat exchanger with circular fins was computationally simulated by a finite element method and probabilistically evaluated in view of the several uncertainties in the performance parameters. Cumulative distribution functions and sensitivity factors were computed for Hoop and Radial stresses due to the structural and thermodynamic random variables. These results are used to identify the most critical design variables in order to optimize the design and make it cost effective. The probabilistic analysis leads to the selection of the …


Computational Models Of Chemical Systems Inspired By Braess’ Paradox, Dante Lepore, Carl Barratt, Pauline Schwartz 2011 Cornell University

Computational Models Of Chemical Systems Inspired By Braess’ Paradox, Dante Lepore, Carl Barratt, Pauline Schwartz

Chemistry and Chemical Engineering Faculty Publications

Systems chemistry is a new discipline which investigates the interactions within a network of chemical reactions. We have studied several computational models of chemical systems inspired by mathematical paradoxes and have found that even simple systems may behave in a counterintuitive, non-linear manner depending upon various conditions. In the present study, we modeled a set of reactions inspired by one such paradox, Braess’ paradox, an interesting phenomenon whereby the introduction of additional capacity (e.g. pathways) in some simple network systems can lead to an unexpected reduction in the overall flow rate of “traffic” through the system. We devised several chemical …


Nitric Oxide-Generating Silicone As A Blood-Contacting Biomaterial, Kagya Amoako 2011 University of New Haven

Nitric Oxide-Generating Silicone As A Blood-Contacting Biomaterial, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

Coagulation upon blood-contacting biomaterials remains a problem for short and long-term clinical applications. This study examined the ability of copper(II)-doped silicone surfaces to generate nitric oxide (NO) and locally inhibit coagulation. Silicone was doped with 3-micron copper (Cu(0)) particles yielding 3 to 10 weight percent (wt%) Cu in 70-μm thick Cu/Silicone polymeric matrix composites (Cu/Si PMCs). At 3, 5, 8 and 10 wt% Cu doping, the surface expression of Cu was 12.1 ± 2.8%, 19.7 ± 5.4%, 29.0 ± 3.8%, and 33.8 ± 6.5% respectively. After oxidizing Cu(0) to Cu(II) by spontaneous corrosion, NO flux, JNO (mol*cm−2*min−1), as measured by …


Development Of A Friction Testing Apparatus For Demoulding Force Prediction, Kevin Delaney, David Kennedy, G. Bissacco 2011 Technological University Dublin

Development Of A Friction Testing Apparatus For Demoulding Force Prediction, Kevin Delaney, David Kennedy, G. Bissacco

Conference Papers

Friction between replication tools and replicated parts determines the force required to demould the part and also the stresses which develop in both the tool and the part during the demoulding process. Standardized equipment and procedures have been developed which strive to improve the repeatability and reproducibility of friction tests. Specific test standards, describing sled-type tests, include JIS K 7125, ISO 8295 and ASTM D1894. However these tests do not produce results which are representative of the conditions typically found within replication tools such as injection moulds or embossing tools. This paper reviews how this challenge has been addressed by …


Toward Increasing Performance And Efficiency In Gas Turbines For Power Generation And Aero-Propulsion Unsteady Simulation Of Angled Discrete-Injection Coolant In A Hot Gas Path Crossflow, Perry L. Johnson 2011 University of Central Florida

Toward Increasing Performance And Efficiency In Gas Turbines For Power Generation And Aero-Propulsion Unsteady Simulation Of Angled Discrete-Injection Coolant In A Hot Gas Path Crossflow, Perry L. Johnson

HIM 1990-2015

This thesis describes the numerical predictions of turbine film cooling interactions using Large Eddy Simulations. In most engineering industrial applications, the Reynolds-Averaged Navier-Stokes equations, usually paired with two-equation models such as k-Greek lowercase letter epsilon] or k-Greek lowercase letter omega], are utilized as an inexpensive method for modeling complex turbulent flows. By resolving the larger, more influential scale of turbulent eddies, the Large Eddy Simulation has been shown to yield a significant increase in accuracy over traditional two-equation RANS models for many engineering flows. In addition, Large Eddy Simulations provide insight into the unsteady characteristics and coherent vortex structures of …


High Frequency Thermally Actuated Single Crystalline Silicon Micromechanical Resonators With Piezoresistive Readout, Amir Rahafrooz 2011 University of Denver

High Frequency Thermally Actuated Single Crystalline Silicon Micromechanical Resonators With Piezoresistive Readout, Amir Rahafrooz

Electronic Theses and Dissertations

Over the past decades there has been a great deal of research on developing high frequency micromechanical resonators. As the two most common and conventional MEMS resonators, piezoelectric and electrostatic resonators have been at the center of attention despite having some drawbacks. Piezoelectric resonators provide low impedances that make them compatible with other low impedance electronic components, however they have low quality factors and complicated fabrication processes. In case of electrostatic resonators, they have higher quality factors but the need for smaller transductions gaps complicates their fabrication process and causes squeezed film damping in Air. In addition, the operation of …


Development Of Optimal Bubble-Seeding Microheaters To Study Nucleate Boiling Heat Transfer In Microgravity, Ryan Martineau 2011 Utah State University

Development Of Optimal Bubble-Seeding Microheaters To Study Nucleate Boiling Heat Transfer In Microgravity, Ryan Martineau

Reports and Proposals

No abstract provided.


Heat Transfer And Friction Augmentation In A Narrow Rectangular Duct With Symmetrical And Non-Symmetrical Wedge-Shaped Turbulators, Michelle Valentino 2011 University of Central Florida

Heat Transfer And Friction Augmentation In A Narrow Rectangular Duct With Symmetrical And Non-Symmetrical Wedge-Shaped Turbulators, Michelle Valentino

Electronic Theses and Dissertations

The need for cleaner and more fuel efficient means to produce electricity is growing steadily. Advancements in cooling technologies contribute to the improvements in turbine efficiency and are used for gas turbines and for power generation in automotive, aviation, as well as in naval applications, and many more. Studies introducing turbulators on walls of internal cooling channels, which can be applied to hot gas components and in recuperative heat exchangers, have been reviewed for their ability to promote heat transfer in the channel while observing pressure loss caused by adding the features. Several types of turbulators have been studied; ribs, …


Model Identification, Updating, And Validation Of An Active Magnetic Bearing High-Speed Machining Spindle For Precision Machining Operation, Adam C. Wroblewski 2011 Cleveland State University

Model Identification, Updating, And Validation Of An Active Magnetic Bearing High-Speed Machining Spindle For Precision Machining Operation, Adam C. Wroblewski

ETD Archive

High-Speed Machining (HSM) spindles equipped with Active Magnetic Bearings (AMBs) are envisioned to be capable of autonomous self-identification and performance self-optimization for stable high-speed and high quality machining operation. High-speed machining requires carefully selected parameters for reliable and optimal machining performance. For this reason, the accuracy of the spindle model in terms of physical and dynamic properties is essential to substantiate confidence in its predictive aptitude for subsequent analyses.This dissertation addresses system identification, open-loop model development and updating, and closed-loop model validation. System identification was performed in situ utilizing the existing AMB hardware. A simplified, nominal open-loop rotor model was …


A Cfd Model Of Mixing In A Microfludic Device For Space Medicine Technology, Terri Lynn Mckay 2011 Cleveland State University

A Cfd Model Of Mixing In A Microfludic Device For Space Medicine Technology, Terri Lynn Mckay

ETD Archive

The DNA Medicine Institute (DMI) is currently developing a device to be used for blood analysis to satisfy the unique requirements of space medicine applications. A key component of that device is the micromixer, which will ensure mixing and dilution of reagents utilized for detection assays. As part of the device design process, the micromixer was modeled, and the mixing characteristics were analyzed and compared to experimental data. The experimental data was based on a top-view of the system and, lacking data throughout the fluid domain, could not provide the insight into the mixing process that modeling could readily provide. …


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