An Investigative Study Into The Relationship Of Bone Morphogenetic Protein Antagonist Expression And Osteocyte Density By Region And Quadrant,
2010
California Polytechnic State University, San Luis Obispo
An Investigative Study Into The Relationship Of Bone Morphogenetic Protein Antagonist Expression And Osteocyte Density By Region And Quadrant, Scott C. Mosher
Master's Theses
The role of cytokines and cell behavior and viability with respect to bone remodeling and bone behavior is an exciting area of orthopedic research. The purpose of this study was to investigate the relationships between BMP antagonist expression and osteocyte density, lacunar densities and osteocyte viability in cortical bone. Samples of unloaded tibial bone obtained from six C57Bl/6 mice were immunohistochemically stained for gremlin and noggin expression and also underwent methyl green staining to determine osteocyte presence. Bone sections were divided into four quadrants (cranial, caudal, medial and lateral) and three regions (proximal, mid shaft and distal), followed by analysis …
Development Of A Novel Noise Delivery System For Jp-8 Ototoxicity Studies,
2010
Air Force Institute of Technology
Development Of A Novel Noise Delivery System For Jp-8 Ototoxicity Studies, John E. Stubbs
Theses and Dissertations
Numerous chemicals with ototoxic properties may cause hearing loss directly, potentiate noise-induced hearing loss, or produce additive effects. Of interest to the US Air Force are studies showing ototoxic effects of JP-8 jet fuel and its hydrocarbon constituents. The Naval Health Research Center (NHRC) at Wright-Patterson AFB, Ohio, in conjunction with the USAF, is studying the ototoxic effects of JP-8 in rats. The study requires a white noise source that is one octave band wide, centered at 8 kHz frequency, delivered from outside of exposure chambers. Sound pressure levels must be within ± 2 dB at all exposure points within …
An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm,
2010
California Polytechnic State University, San Luis Obispo
An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore
Master's Theses
The humerus of a racing horse Thoroughbred is highly susceptible to stress fractures at a characteristic location as a result of cyclic loading. The propensity of a Thoroughbred to exhibit humeral fracture has made equines useful models in the epidemiology of stress fractures. In this study, a racing Thoroughbred humerus was simulated during training using a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different training programs were incorporated …
