Space Habitation and Life Support Commons^™

Neuroinflammatory Signaling And Immune Cell Infiltration Differ In Brains Of Rats Exposed To Space Radiation And Social Isolation, Austin M. Adkins, Zachary N. M. Luyo, Alea F. Boden, Riley S. Heerbrandt, Richard A. Britten, Laurie L. Wellman, Larry D. Sanford

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

Astronauts on the proposed Mars missions will be exposed to extended periods of social isolation (SI) and space radiation (SR). SI and SR-induced immune dysregulation can result in persistent neuroinflammation and neuronal damage which could negatively impact an astronaut’s health and ability to maintain adequate levels of performance. The synergistic effects of combined SI and SR on immune system functionality and the brain remain unknown. Determining how single and combined inflight stressors modulate the immune system is crucial for fully understanding pathways impacting astronaut health and performance. We used ground-based analogs of SI and SR in rodent models to investigate …

Ground Testing Of A Magnetic-Electrostatic Separation System For Lunar Regolith Beneficiation, Peter Bachle, Charles Wood, Jeffrey Smith, Fateme Rezaei, David Bayless, William Schonberg, Daoru Han

Materials Science and Engineering Faculty Research & Creative Works

The separation of lunar regolith by mineral composition and size category is useful forin-situ resource utilization (ISRU). The research presented herein discusses the designing and development of equipment that has the potential to separate lunar regolith into aluminum, iron-titanium, and magnesium-iron ores. Along with the metal ore separation, this equipment shows the potential to separate regolith by size categories. The combined effect of these separation methods generates output that is valuable to subsequent use in metal and oxygen extraction, additive manufacturing, and regolith sintering processes. The designed equipment uses a dual-strength magnet system with N42 and N52 neodymium magnets for …

Extending The Applicability Of Thermal Protection System Ballistic Limit Equations Beyond The Testable Regime, William P. Schonberg, Michael D. Squire

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Spacecraft use thermal insulation in their design, which is usually placed on their exterior. As such, it is susceptible to high-speed impacts by meteoroids and orbital debris, which can damage it to a point where the protection it offers is below acceptable limits. It is important to be able to characterize expected levels of damage stemming from such high-speed impacts. In this paper, we extend the applicability of a previously developed ballistic limit equation (BLE) for one such thermal insulation material using the results of a series of Smooth Particle Hydrodynamics Code (SPHC) impact simulations at velocities in excess of …

Lunar Refueling: Legal Issues And Suggested Solutions, Francesca Giannoni-Crystal

Journal of Law and Mobility

The establishment of settlements and economic activities on the Moon is expected to occur in the near future, positioning the Moon as a critical hub for continued exploration of the Solar System. Central to this development is the creation of a lunar refueling industry, which will play a pivotal role in supporting lunar activities and fostering further exploration.

Lunar refueling, which includes extracting local resources like lunar ice water to obtain hydrogen, offers key benefits, such as reducing the need for resupply missions from Earth, lowering launch costs, extending mission capabilities, and enabling launches from the Moon, which are more …

Man On Mars: How Can International Space Law Limit The Environmental Consequences Of The Coming Rush For Resources In Space, Elizabeth Anne Henderson

Michigan Journal of International Law

The body of international law governing space has stood at a standstill for decades. The five central treaties regulating this area of law are not only vague, but they have also become a hindrance to the global community’s ability to address the rapidly intensifying second space race. The treaties do not adequately state who space belongs to, who is entitled to take advantage of the natural resources of celestial bodies, or what protections are afforded to celestial environments in the face of impending mining and resource extraction projects. This impasse within international law has not stopped entrepreneurs and corporations from …

Sex-Dependent Changes In Risk-Taking Predisposition Of Rats Following Space Radiation Exposure, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Charles Nguyen, Richard A. Britten

Department Radiation Oncology & Biophysics Faculty Publications

The Artemis missions will establish a sustainable human presence on the Moon, serving as a crucial steppingstone for future Mars exploration. Astronauts on these ambitious missions will have to successfully complete complex tasks, which will frequently involve rapid and effective decision making under unfamiliar or high-pressure conditions. Exposure to low doses of space radiation (SR) can impair key executive functions critical to decision making. This study examined the effects of exposure to 10 cGy of Galactic Cosmic Ray simulated radiation (GCRsim) on decision-making performance in male and female rats with a naturally low predisposition for risk-taking (RTP) prior to exposure. …

A Two-Hit Model Of Executive Dysfunction: Simulated Galactic Cosmic Radiation Primes Latent Deficits Revealed By Sleep Fragmentation, Richard A. Britten, Ella N. Tamgue, Paola Arriaga Alvarado, Arriyam S. Fesshaye, Larry D. Sanford

Department Radiation Oncology & Biophysics Faculty Publications

Future Artemis-class missions to Mars will expose astronauts to prolonged space radiation (SR), sleep disruption, and operational demands requiring greater autonomy, placing decision making and executive function at heightened risk. Both SR and sleep fragmentation (SF) independently impair cognition, yet their combined effects remain poorly understood. Using the Associative Recognition Memory and Interference (ARMIT) task, we assessed cognitive performance in male rats exposed to 10 cGy of Galactic Cosmic Ray simulation (GCRsim), SF, or both. Under well-rested conditions, GCRsim-exposed rats exhibited overt deficits in the C.1.2 stage, performing at chance when reinforcement contingencies shifted, consistent with impaired cognitive flexibility. In …

Development Of A Model For Fire Spread In Low-Gravity Conditions, Kathleen Martinus

The Journal of Purdue Undergraduate Research

No abstract provided.

Nasa Microgreen Cultivation In Space Utilizing Pegda Hydrogels, Thomas Alarcon Ali, Zohaib Gabriel Khan, Ariel Marroquin, Samuel Martinez, Fabiha Samiha, Emily Yong

Publications and Research

During long-term space expeditions, it is crucial that astronauts receive the nutrients they need to maintain their overall health. While the current space diet of palatable foods is commendable and constantly evolving, nutritional content and food quality degrades over long durations. Microgreens are excellent candidates for space cultivation because they are nutrient-dense, young plants that are are densely grown and harvested when leaves are just emerging. However, antigravity, microgreen fragility, degradation speed, contamination, and limited water resources are substantial barriers to doing so. This study aims to address these challenges by cultivating microgreens inside a hydrogel, a soilless medium, to …

Kinetic Modeling Of Dust Grain Dynamics In Electrostatic Sieving, Aaron Berkhoff, Easton Ingram, Fateme Rezaei, Jeffrey Smith, David Bayless, William Schonberg, Daoru Han

Chemical and Biochemical Engineering Faculty Research & Creative Works

A new kinetic particle modeling framework was developed to investigate electrostatic transport of lunar regolith dust particles with applications to the concept of electrostatic sieving. the new approach is based on kinetic particle dynamics and includes major modules of sampling the particle size distribution, solving electric fields, and tracking motion of charged dust grains. a case study for a concept of electrostatic sieving was chosen to validate the new model. the simulation achieved similar performance of particle size classification as reported in the literature. the new model is computationally efficient (takes a few minutes on a PC-type laptop computer) so …

Space Radiation Assessment And Mitigation: Meeting The Growing Demand For Shielding Solutions By Enhancing Models And Exploring Novel Shielding Opportunities, M. Laura Sorgi Johann

Doctoral Dissertations and Master's Theses

The rapid growth of satellite technology and the increasing presence of vulnerable technology and human life in space have highlighted the need for improved shielding materials. Industry standard protocols for shielding are being pushed to their limits as we gain a deeper understanding of the harsh space environment and as chip sizes approach the scale of radiation wavelengths. Furthermore, the commercialization of space is attracting interest from industries such as pharmaceuticals and semiconductor crystal growing, as they explore the potential benefits of zero-gravity production environments. However, the eagerness to develop lighter shielding and the lack of consideration for existing tools …

Winning Battle For Key And Core Technologies In Emerging Fields—Inspiration Based On 863 Program Related Projects, Guangzu Bai, Li Li, Hongfei Meng, Qiang Wang, Xiaoyang Cao, Anrong Liu, Bo Cheng, Mimi Zhan, Jing Li, Leiei Cui, Xiangwan Du

Bulletin of Chinese Academy of Sciences (Chinese Version)

Emerging technology fields have become the main battleground for strategic competition among major powers today, with key and core technologies serving as crucial approach in shaping a nation’s international competitive advantage. This study, from the perspective of national strategy, profoundly understands the significant importance of winning the key and core technology battle in emerging fields. Based on this understanding, it starts with a comparison between the implementation background of the 863 Program and the current reality. It systematically summarizes valuable experiences from projects aimed at advancing key and core technologies in emerging fields, and puts forward reflections and suggestions for …

Microgravity Aeroponics System Project, Andrew W. Diddle

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Engineering at Morehead State University in partial fulfillment of the requirements for the degree Master of Science by Andrew W. Diddle on April 22, 2024.

A Machine Learning Model Of Perturb-Seq Data For Use In Space Flight Gene Expression Profile Analysis, Liam F. Johnson, James Casaletto, Lauren Sanders, Sylvain Costes

Graduate Industrial Research Symposium

The genetic perturbations caused by spaceflight on biological systems tend to have a system-wide effect which is often difficult to deconvolute it into individual signals with specific points of origin. Single cell multi-omic data can provide a profile of the perturbational effects, but does not necessarily indicate the initial point of interference within the network. The objective of this project is to take advantage of large scale and genome-wide perturbational datasets by using them to train a tuned machine learning model that is capable of predicting the effects of unseen perturbations in new data. Perturb-Seq datasets are large libraries of …

Extraterrestrial Life: The Possibility Of A Human-Alien Interaction, Ariana M. Piscoya

CAFE Symposium 2024

We all have heard of at least one case where someone assured having seen a flying extraterrestrial object. There are thousands of thousands of videos we can find online that “prove” the existence of aliens. In the hypothetical case where aliens are really out there, why haven't we been able to talk to them and look at them face-to-face? A human-extraterrestrial interaction has not yet been achieved for two reasons. First, alien energy is much more powerful than that of humans, so it would require thousands of thousands of years for the human race to develop a technology able to …

Different Spectrum Of Space Radiation Induced Cognitive Impairments In Radiation-Naïve And Adapted Rats, Richard A. Britten, Arriyam S. Fesshaye, Alyssa Tidmore, Ella N. Tamgue, Paola A. Alvarado-Arriaga

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

NASA's decision to resume manned deep space mission, first to the Moon and then Mars, necessitated a detailed assessment of the potential health effects that astronauts may experience on long-duration missions. Multiple studies suggest that there may be significant space radiation (SR)-induced impairment of neurocognitive processes, including advanced executive functions. However, given the multitude of SR-induced changes in the CNS, it is possible that completely different SR-induced sequelae will be induced in previously exposed individuals. Thus, current risk estimates are likely to be pertinent only for the early stages of a deep space mission, and even then only for astronauts …

Optimizing Multi-Agent Network For Target Localization Through Mutual Information Maximization, Bibek Adhikari

Mechanical and Aerospace Engineering Theses - Archive

A multi-agent network is a system comprising multiple interacting agents that coexist collaboratively within a networked, autonomous environment. The thesis addresses the target localization problem using a multi-rover network, described as autonomous agents, using an information-theoretic distributed control framework. The objective of the mission, through the integration of the particle filter representation of the posterior probability distribution of the target state and the observable, is to compute control input to arrange agents’ locations, maximizing the mutual information between the target’s position and sensor measurements. Consequently, the method leads to future observation which minimizes the future uncertainty of the target state. …

Repurposing The United Nations Trusteeship Council To Govern The Establishment Of Outer Space Settlements, Andrew Wulf

Northwestern Journal of International Law & Business

Current existing international law and treaties on outer space do not address or regulate private actors’ property claims or human settlements in outer space. American companies such as SpaceX and Blue Origin, as well as countries like the United States, Russia, and China, are seeking to create colonies on the Moon and Mars. However, there is no international legal authority to allow or regulate this. In order to legitimize and control this impending outgrowth of human settlements, this paper proposes that the U.N. Trusteeship Council be repurposed to govern non-state actors’ claims of outer space property.

First, this paper explains …

Magnetic Separation Of Lunar Regolith Simulants With Applications To In Situ Resource Utilization On The Moon, Peter Bachle, Jeffrey Smith, Fateme Rezaei, David Bayless, William Schonberg, Daoru Han

Materials Science and Engineering Faculty Research & Creative Works

The development of in situ resource utilization (ISRU) for metal extraction is imperative as a steppingstone for habitation construction in lunar and non-terrestrial environments. Separation of minerals by chemical composition is important to optimize metal and oxygen liberation from lunar ore. to this effect, devices capable of separating aluminum bearing minerals from iron-bearing minerals from the lunar regolith simulants have been developed. Twenty-eight different simulants have been used in this study. a dual-belt separator was designed to reduce middlings. Para-magnetic minerals were reliably separated using a neodymium N52-magnet-separator system. Effective separation of aluminum-bearing minerals from iron-bearing minerals was greater than …

A Concept Of Producing Aluminum In-Situ On The Moon Through Molten Salt Electrolysis, Jacob N. Ortega, Jeffrey Smith, Fateme Rezaei, David Bayless, William Schonberg, Daniel Stutts, Daoru Han

Materials Science and Engineering Faculty Research & Creative Works

This paper presents a concept of producing aluminum in-situ on the lunar surface, namely, the Lunar In-Situ Aluminum Production through Molten Salt Electrolysis (LISAP-MSE) method developed at Missouri University of Science and Technology. This paper aims to demonstrate the use of electro-deoxidation to reduce aluminum oxide (i.e., alumina) into aluminum and oxygen gas via electrolysis in a molten salt bath for the production of aluminum on the Moon. It is shown that with a steady supply of hydrogen chloride, this in-situ resource utilization (ISRU) method could supply several necessary materials consumed in the electro-deoxidation process except hydrogen chloride to produce …