Applied Mathematics Commons^™

A Model For Spheroid Versus Monolayer Response Of Sk-N-Sh Neuroblastoma Cells To Treatment With 15-Deoxy-Pgj2, Dorothy I. Wallace, Ann Dunham, Paula X. Chen, Michelle Chen, Milan Huynh, Evan Rheingold, Olivia F. Prosper

Mathematics Faculty Publications

Researchers have observed that response of tumor cells to treatment varies depending on whether the cells are grown in monolayer, as in vitro spheroids or in vivo. This study uses data from the literature on monolayer treatment of SK-N-SH neuroblastoma cells with 15-deoxy-PGJ₂ and couples it with data on growth rates for untreated SK-N-SH neuroblastoma cells grown as multicellular spheroids. A linear model is constructed for untreated and treated monolayer data sets, which is tuned to growth, death, and cell cycle data for the monolayer case for both control and treatment with 15-deoxy-PGJ₂. The monolayer …

The Kretschmann Scalar, Charles G. Torre

How to... in 10 minutes or less

On a pseudo-Riemannian manifold with metric g, the "Kretschmann scalar" is a quadratic scalar invariant of the Riemann R tensor of g, defined by contracting all indices with g. In this worksheet we show how to calculate the Kretschmann scalar from a metric.

Inżynieria Chemiczna Lab., Wojciech M. Budzianowski

Wojciech Budzianowski

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Simulation Of Nuclear Fusion Using A One Dimensional Particle In Cell Method, Steven T. Margell

Cal Poly Humboldt theses and projects

In this thesis several novel techniques are developed to simulate fusion events in an isotropic, electrostatic three-dimensional Deuterium-Tritium plasma. These techniques allow us to accurately predict three-dimensional collision events with a one-dimensional model while simultaneously reducing compute time via a nearest neighbor algorithm. Furthermore, a fusion model based on first principles is developed that yields an average fusion reactivity which correlates well with empirical results.

Models Of Internal Waves In The Presence Of Currents, Alan Compelli, Rossen Ivanov

Conference papers

A fluid system consisting of two domains is examined. The system is considered as being bounded at the bottom and top by a flatbed and wave-free surface respectively. An internal wave propagating in one direction, driven by gravity, acts as a free common interface between the fluids. Various current profiles are considered. The Hamiltonian of the system is determined and expressed in terms of canonical wave-related variables. Limiting behaviour is examined and compared to that of other known models. The linearised equations as well as long-wave approximations are formulated. The presented models provide potential applications to modelling of internal geophysical …

Factorized Runge-Kutta-Chebyshev Methods, Stephen O'Sullivan

Conference papers

The second-order extended stability Factorized Runge-Kutta-Chebyshev (FRKC2) class of explicit schemes for the integration of large systems of PDEs with diffusive terms is presented. FRKC2 schemes are straightforward to implement through ordered sequences of forward Euler steps with complex stepsizes, and easily parallelised for large scale problems on distributed architectures.

Preserving 7 digits for accuracy at 16 digit precision, the schemes are theoretically capable of maintaining internal stability at acceleration factors in excess of 6000 with respect to standard explicit Runge-Kutta methods. The stability domains have approximately the same extents as those of RKC schemes, and are a third longer …

A Competitive Random Sequential Adsorption Model For Immunoassay Activity, Dana Mackey, Eilis Kelly, Robert Nooney

Conference papers

Immunoassays rely on highly specific reactions between antibodies and antigens and are used in biomedical diagnostics applications to detect biomarkers for a variety of diseases. Antibody immobilization to solid interfaces through random adsorption is a widely used technique but has the disadvantage of severely reducing the antigen binding activity and, consequently, the assay performance. This paper proposes a simple mathematical framework, based on the theory known as competitive random sequential adsorption (CRSA), for describing how the activity of immobilized antibodies depends on their orientation and packing density and generalizes a previous model by introducing the antibody aspect ratio as an …

Sphere Representations, Stacked Polytopes, And The Colin De Verdière Number Of A Graph, Lon Mitchell, Lynne Yengulalp

Mathematics Faculty Publications

We prove that a k-tree can be viewed as a subgraph of a special type of (k + 1)- tree that corresponds to a stacked polytope and that these “stacked” (k + 1)-trees admit representations by orthogonal spheres in R k+1. As a result, we derive lower bounds for Colin de Verdi`ere’s µ of complements of partial k-trees and prove that µ(G) + µ(G) > |G| − 2 for all chordal G.

Existence Of Periodic Solutions For A Quantum Volterra Equation, Muhammad Islam, Jeffrey T. Neugebauer

Mathematics Faculty Publications

The objective of this paper is to study the periodicity properties of functions that arise in quantum calculus, which has been emerging as an important branch of mathematics due to its various applications in physics and other related fields. The paper has two components. First, a relation between two existing periodicity notions is established. Second, the existence of periodic solutions of a q-Volterra integral equation, which is a general integral form of a first order q-difference equation, is obtained. At the end, some examples are provided. These examples show the effectiveness of the relation between the two periodicity notions that …

Stochastic Models Of Evidence Accumulation In Changing Environments, Alan Veliz-Cuba, Zachary P. Kilpatrick, Krešimir Josić

Mathematics Faculty Publications

Organisms and ecological groups accumulate evidence to make decisions. Classic experiments and theoretical studies have explored this process when the correct choice is fixed during each trial. However, we live in a constantly changing world. What effect does such impermanence have on classical results about decision making? To address this question we use sequential analysis to derive a tractable model of evidence accumulation when the correct option changes in time. Our analysis shows that ideal observers discount prior evidence at a rate determined by the volatility of the environment, and the dynamics of evidence accumulation is governed by the information …

Almost Automorphic Solutions Of Delayed Neutral Dynamic Systems On Hybrid Domains, Murat Adıvar, Halis Can Koyuncuoğlu, Youssef Raffoul

Mathematics Faculty Publications

We study the existence of almost automorphic solutions of the delayed neutral dynamic system on hybrid domains that are additively periodic. We use exponential dichotomy and prove uniqueness of projector of exponential dichotomy to obtain some limit results leading to sufficient conditions for existence of almost automorphic solutions to neutral system. Unlike the existing literature we prove our existence results without assuming boundedness of the coefficient matrices in the system. Hence, we significantly improve the results in the existing literature. Finally, we also provide an existence result for an almost periodic solutions of the system.

Positive Solutions For A Singular Fourth Order Nonlocal Boundary Value Problem, John M. Davis, Paul W. Eloe, John R. Graef, Johnny Henderson

Mathematics Faculty Publications

Positive solutions are obtained for the fourth order nonlocal boundary value problem, u⁽⁴⁾=f(x,u), 0 < x < 1, u(0) = u''(0) = u'(1) = u''(1) - u''(2/3)=0, where f(x,u) is singular at x = 0, x=1, y=0, and may be singular at y=∞. The solutions are shown to exist at fixed points for an operator that is decreasing with respect to a cone.

Radical Recognition In Off-Line Handwritten Chinese Characters Using Non-Negative Matrix Factorization, Xiangying Shuai

Senior Projects Spring 2016

In the past decade, handwritten Chinese character recognition has received renewed interest with the emergence of touch screen devices. Other popular applications include on-line Chinese character dictionary look-up and visual translation in mobile phone applications. Due to the complex structure of Chinese characters, this classification task is not exactly an easy one, as it involves knowledge from mathematics, computer science, and linguistics.

Given a large image database of handwritten character data, the goal of my senior project is to use Non-Negative Matrix Factorization (NMF), a recent method for finding a suitable representation (parts-based representation) of image data, to detect specific …

Modeling Of Piezoelectric Traveling Wave Rotary Ultrasonic Motors With The Finite Volume Method, Ivan Arturo Renteria Marquez

Open Access Theses & Dissertations

In 1983 Toshiiku Sashida developed a new motor concept called Piezoelectric Traveling Wave Rotary Ultrasonic Motor (PTRUSM). The advantages of these motors include high torque at low speed, absence of a generated magnetic field, and high potential for miniaturization. Unfortunately PTRUSMs have some disadvantages that limit the areas of applications for these types of motors. The disadvantages are a short operating life (about 1000 hours), small output power, and the need of a complex motor controller.

On one hand, these motors have been used in satellites, mobile phones, photocopiers, robotic arms, telescopes, automobiles, and camera autofocusing. On the other hand, …

A Study Of The Effect Of Harvesting On A Discrete System With Two Competing Species, Rebecca G. Clark

Theses and Dissertations

This is a study of the effect of harvesting on a system with two competing species. The system is a Ricker-type model that extends the work done by Luis, Elaydi, and Oliveira to include the effect of harvesting on the system. We look at the uniform bound of the system as well as the isoclines and perform a stability analysis of the equilibrium points. We also look at the effects of harvesting on the stability of the system by looking at the bifurcation of the system with respect to harvesting.

A Two Host Species Stage-Structured Model Of West Nile Virus Transmission, Taylor A. Beebe

Theses and Dissertations

We develop and evaluate a novel host-vector model of West Nile virus (WNV) transmission that incorporates multiple avian host species and host stage-structure (juvenile and adult stages), with both species-specific and stage-specific biting rates of vectors on hosts. We use this model to explore WNV transmission dynamics that occur between vectors and multiple structured host populations as a result of heterogeneous biting rates. Our analysis shows that increased exposure of juvenile hosts results in earlier, more intense WNV transmission when compared to the effects of differential host species exposure, regardless of other parameter values. We also find that, in addition …

Heuristic And Exact Algorithms For The Two-Machine Just In Time Job Shop Scheduling Problem, Mohammed Al Salem, Leonardo Bedoya-Valencia, Ghaith Rabadi

Engineering Management & Systems Engineering Faculty Publications

The problem addressed in this paper is the two-machine job shop scheduling problem when the objective is to minimize the total earliness and tardiness from a common due date (CDD) for a set of jobs when their weights equal 1 (unweighted problem). This objective became very significant after the introduction of the Just in Time manufacturing approach. A procedure to determine whether the CDD is restricted or unrestricted is developed and a semirestricted CDD is defined. Algorithms are introduced to find the optimal solution when the CDD is unrestricted and semirestricted. When the CDD is restricted, which is a much …

Controllability Of Neutral Stochastic Integro-Differential Evolution Equations Driven By A Fractional Brownian Motion, El Hassan Lakhel, Mark A. Mckibben

Mathematics Faculty Publications

We establish sufficient conditions for the controllability of a certain class of neutral stochastic functional integro-differential evolution equations in Hilbert spaces. The results are obtained using semigroup theory, resolvent operators and a fixed-point technique. An application to neutral partial integro-differential stochastic equations perturbed by fractional Brownian motion is given.

A Discontinuous Galerkin Method For Unsteady Two-Dimensional Convective Flows, Andreas C. Aristotelous, N. C. Papanicolaou

Mathematics Faculty Publications

We develop a High-Order Symmetric Interior Penalty (SIP) Discontinuous Galerkin (DG) Finite Element Method (FEM) to investigate two-dimensional in space natural convective flows in a vertical cavity. The physical problem is modeled by a coupled nonlinear system of partial differential equations and admits various solutions including stable and unstable modes in the form of traveling and/or standing waves, depending on the governing parameters. These flows are characterized by steep boundary and internal layers which evolve with time and can be well-resolved by high-order methods that also are adept to adaptive meshing. The standard no-slip boundary conditions which apply on the …

The Global Stability Of The Solution To The Morse Potential In A Catastrophic Regime, Weerapat Pittayakanchit

HMC Senior Theses

Swarms of animals exhibit aggregations whose behavior is a challenge for mathematicians to understand. We analyze this behavior numerically and analytically by using the pairwise interaction model known as the Morse potential. Our goal is to prove the global stability of the candidate local minimizer in 1D found in A Primer of Swarm Equilibria. Using the calculus of variations and eigenvalues analysis, we conclude that the candidate local minimizer is a global minimum with respect to all solution smaller than its support. In addition, we manage to extend the global stability condition to any solutions whose support has a single …