High-Order Flexible Multirate Integrators For Multiphysics Applications, 2021 Southern Methodist University

#### High-Order Flexible Multirate Integrators For Multiphysics Applications, Rujeko Chinomona

*Mathematics Theses and Dissertations*

Traditionally, time integration methods within multiphysics simulations have been chosen to cater to the most restrictive dynamics, sometimes at a great computational cost. Multirate integrators accurately and efficiently solve systems of ordinary differential equations that exhibit different time scales using two or more time steps. In this thesis, we explore three classes of time integrators that can be classified as one-step multi-stage multirate methods for which the slow dynamics are evolved using a traditional one step scheme and the fast dynamics are solved through a sequence of modified initial value problems. Practically, the fast dynamics are subcycled using a small ...

Lexicographic Sensitivity Functions For Nonsmooth Models In Mathematical Biology, 2021 University of Maine

#### Lexicographic Sensitivity Functions For Nonsmooth Models In Mathematical Biology, Matthew D. Ackley

*Electronic Theses and Dissertations*

Systems of ordinary differential equations (ODEs) may be used to model a wide variety of real-world phenomena in biology and engineering. Classical sensitivity theory is well-established and concerns itself with quantifying the responsiveness of such models to changes in parameter values. By performing a sensitivity analysis, a variety of insights can be gained into a model (and hence, the real-world system that it represents); in particular, the information gained can uncover a system's most important aspects, for use in design, control or optimization of the system. However, while the results of such analysis are desirable, the approach that classical ...

Population And Evolution Dynamics In Predator-Prey Systems With Anti-Predation Responses, 2021 The University of Western Ontario

#### Population And Evolution Dynamics In Predator-Prey Systems With Anti-Predation Responses, Yang Wang

*Electronic Thesis and Dissertation Repository*

This thesis studies the impact of anti-predation strategy on the population dynamics of predator-prey interactions. This work includes three research projects.

In the first project, we study a system of delay differential equations by considering both benefit and cost of anti-predation response, as well as a time delay in the transfer of biomass from the prey to the predator after predation. We reveal some insights on how the anti-predation response level and the biomass transfer delay jointly affect the population dynamics; we also show how the nonlinearity in the predation term mediated by the fear effect affects the long term ...

Predicting Tumor Response To Radiotherapy Based On Estimation Of Non-Treatment Parameters, 2021 Lafayette College

#### Predicting Tumor Response To Radiotherapy Based On Estimation Of Non-Treatment Parameters, Yutian Huang, Allison L. Lewis

*Spora: A Journal of Biomathematics*

Though clinicians can now collect detailed information about a variety of tumor characteristics as a tumor evolves, it remains difficult to predict the efficacy of a given treatment prior to administration. Additionally, the process of data collection may be invasive and expensive. Thus, the creation of a framework for predicting patient response to treatment using only information collected prior to the start of treatment could be invaluable. In this study, we employ ordinary differential equation models for tumor growth and utilize synthetic data from a cellular automaton model for calibration. We investigate which parameters have the most influence upon treatment ...

Entropic Dynamics Of Networks, 2021 Department of Physics, University at Albany, State University of New York

#### Entropic Dynamics Of Networks, Felipe Xavier Costa, Pedro Pessoa

*Northeast Journal of Complex Systems (NEJCS)*

Here we present the entropic dynamics formalism for networks. That is, a framework for the dynamics of graphs meant to represent a network derived from the principle of maximum entropy and the rate of transition is obtained taking into account the natural information geometry of probability distributions. We apply this framework to the Gibbs distribution of random graphs obtained with constraints on the node connectivity. The information geometry for this graph ensemble is calculated and the dynamical process is obtained as a diffusion equation. We compare the steady state of this dynamics to degree distributions found on real-world networks.

A Dynamic Energy Budget Model Of Ornate Box Turtle Shell Growth, 2021 University of Wisconsin-Stout

#### A Dynamic Energy Budget Model Of Ornate Box Turtle Shell Growth, Tyler Skorczewski, Brandon Andersen

*Spora: A Journal of Biomathematics*

Many aspects of box turtle development may depend on size rather than age. Notable examples include sexual maturity and the development of the fully closing hinge in the shell that allows box turtles to completely hide in their shells. Thus, it is important to understand how turtles grow in order to have a complete understanding of turtle biology. Previous studies show that turtle shell growth behaves in a logistic manner. These studies use functional models that fit the data well but do little to explain mechanisms. In this work we use the ideas found in dynamic energy budget theory to ...

Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, 2021 Virginia Commonwealth University

#### Flattening The Curve: The Effects Of Intervention Strategies During Covid-19, Kelly A. Reagan, Rachel J. Pryor, Gonzalo M. Bearman, David M. Chan

*Spora: A Journal of Biomathematics*

COVID-19 has plagued countries worldwide due to its infectious nature. Social distancing and the use of personal protective equipment (PPE) are two main strategies employed to prevent its spread. A SIR model with a time-dependent transmission rate is implemented to examine the effect of social distancing and PPE use in hospitals. These strategies’ effect on the size and timing of the peak number of infectious individuals are examined as well as the total number of individuals infected by the epidemic. The effect on the epidemic of when social distancing is relaxed is also examined. Overall, social distancing was shown to ...

Undetermined Coefficients: A Fully Generalized Approach, 2021 Old Dominion University

#### Undetermined Coefficients: A Fully Generalized Approach, Taylor Powell

*Undergraduate Research Symposium*

In this presentation, I outline the development of a fully-generalized solution of linear, non-homogeneous differential equations with constant coefficients and whose non-homogeneous function is any product of sinusoidal, exponential, and polynomial functions. This particular method does not require the reader to work with annihilator operators or additional related ODEs, and only requires an understanding of summation notation, matrix multiplication, and calculus. Additionally, this method provides a straightforward way to develop a program to implement the technique, and potentially reduces the time-complexity for solutions with comparisons to other methods.

Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, 2021 Washington State University

#### Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, Heather Gudaz, Henry A. Ogu, Elissa J. Schwartz

*Spora: A Journal of Biomathematics*

One of many risks facing HIV+ individuals is the development of kidney dysfunction and end stage kidney disease (ESKD). A differential equation-based mathematical model was developed to assess the impact of antiretroviral therapy on the progression to kidney disease and on reducing mortality due to kidney failure. Analytical and numerical predictions of long-term HIV+ ESKD prevalence show that therapy can lead to either extremely low levels of disease prevalence or increased prevalence, depending on drug efficacy levels and mechanisms of action. Maintenance of HIV+ ESKD prevalence below one individual is possible with sufficient efficacy (e.g., 99%) against the progression ...

Green's Function For The Schrodinger Equation With A Generalized Point Interaction And Stability Of Superoscillations, 2021 Chapman University

#### Green's Function For The Schrodinger Equation With A Generalized Point Interaction And Stability Of Superoscillations, Yakir Aharonov, Jussi Behrndt, Fabrizio Colombo, Peter Schlosser

*Mathematics, Physics, and Computer Science Faculty Articles and Research*

In this paper we study the time dependent Schrödinger equation with all possible self-adjoint singular interactions located at the origin, which include the *δ* and *δ*'-potentials as well as boundary conditions of Dirichlet, Neumann, and Robin type as particular cases. We derive an explicit representation of the time dependent Green's function and give a mathematical rigorous meaning to the corresponding integral for holomorphic initial conditions, using Fresnel integrals. Superoscillatory functions appear in the context of weak measurements in quantum mechanics and are naturally treated as holomorphic entire functions. As an application of the Green's function we study ...

Supercritical And Subcritical Pitchfork Bifurcations In A Buckling Problem For A Graphene Sheet Between Two Rigid Substrates, 2021 The University of Akron

#### Supercritical And Subcritical Pitchfork Bifurcations In A Buckling Problem For A Graphene Sheet Between Two Rigid Substrates, Jake Grdadolnik

*Williams Honors College, Honors Research Projects*

In this paper we study a model of the buckling of a sheet of graphene between two rigid substrates. We seek to understand the buckling of the sheet as the substrate separation is varied with a fixed load on each end of the sheet. We write down the expression for total energy of the system and from it derive a 2-point nonlinear boundary-value problem whose solutions are equilibrium configurations of the sheet. We cannot get an explicit solution. Instead, we perform a bifurcation analysis by using asymptotics to approximate solutions on the bifurcating branches near the bifurcation points. The bifurcating ...

A Generalized Polar-Coordinate Integration Formula, Oscillatory Integral Techniques, And Applications To Convolution Powers Of Complex-Valued Functions On $\Mathbb{Z}^D$, 2021 Colby College

#### A Generalized Polar-Coordinate Integration Formula, Oscillatory Integral Techniques, And Applications To Convolution Powers Of Complex-Valued Functions On $\Mathbb{Z}^D$, Huan Q. Bui

*Honors Theses*

In this thesis, we consider a class of function on $\mathbb{R}^d$, called positive homogeneous functions, which interact well with certain continuous one-parameter groups of (generally anisotropic) dilations. Generalizing the Euclidean norm, positive homogeneous functions appear naturally in the study of convolution powers of complex-valued functions on $\mathbb{Z}^d$. As the spherical measure is a Radon measure on the unit sphere which is invariant under the symmetry group of the Euclidean norm, to each positive homogeneous function $P$, we construct a Radon measure $\sigma_P$ on $S=\{\eta \in \mathbb{R}^d:P(\eta)=1\}$ which is invariant under ...

Analytic Solutions For Diffusion On Path Graphs And Its Application To The Modeling Of The Evolution Of Electrically Indiscernible Conformational States Of Lysenin, 2020 Boise State University

#### Analytic Solutions For Diffusion On Path Graphs And Its Application To The Modeling Of The Evolution Of Electrically Indiscernible Conformational States Of Lysenin, K. Summer Ware

*Boise State University Theses and Dissertations*

Memory is traditionally thought of as a biological function of the brain. In recent years, however, researchers have found that some stimuli-responsive molecules exhibit memory-like behavior manifested as history-dependent hysteresis in response to external excitations. One example is lysenin, a pore-forming toxin found naturally in the coelomic fluid of the common earthworm *Eisenia fetida*. When reconstituted into a bilayer lipid membrane, this unassuming toxin undergoes conformational changes in response to applied voltages. However, lysenin is able to "remember" past history by adjusting its conformational state based not only on the amplitude of the stimulus but also on its previous its ...

Sum Of Cubes Of The First N Integers, 2020 California State University, San Bernardino

#### Sum Of Cubes Of The First N Integers, Obiamaka L. Agu

*Electronic Theses, Projects, and Dissertations*

In Calculus we learned that Sum^{n}_{k=1} k = [n(n+1)]/2 , that Sum^{n}_{k=1} k^2 = [n(n+1)(2n+1)]/6 , and that Sum^{n}_{k=1} k^{3} = (n(n+1)/2)^{2}. These formulas are useful when solving for the area below quadratic or cubic function over an interval [a, b]. This tedious process, solving for areas under a quadratic or a cubic, served as motivation for the introduction of Riemman integrals. For the overzealous math student, these steps were replaced by a simpler method of evaluating antiderivatives at ...

Asymptotic Analysis Of Radial Point Rupture Solutions For Elliptic Equations, 2020 Illinois State University

#### Asymptotic Analysis Of Radial Point Rupture Solutions For Elliptic Equations, Attou Miloua

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.

Personalized Immunotherapy Treatment Strategies For A System Of Chronic Myelogenous Leukemia, 2020 Tijuana Institute of Technology, Mexico

#### Personalized Immunotherapy Treatment Strategies For A System Of Chronic Myelogenous Leukemia, Paul Valle

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.

Viewing Ode Models Through A New Lens: The Generalized Linear Chain Trick, 2020 University of Nevada, Reno

#### Viewing Ode Models Through A New Lens: The Generalized Linear Chain Trick, Paul Hurtado, Cameron Richards

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.

Applying Immuno-Epidemiology Principles To Violence, 2020 University of Tennessee, Knoxville

#### Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.

Various Mathematical Models To Study Covid-19 Pandemic Dynamics With Quarantine, Hospitalized And Non-Pharmaceutical Interventions As Control Strategies, 2020 JC DAV COLLEGE DASUYA, PUNJAB, INDIA

#### Various Mathematical Models To Study Covid-19 Pandemic Dynamics With Quarantine, Hospitalized And Non-Pharmaceutical Interventions As Control Strategies, Amit Sharma, Bhanu Gupta

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.

A Mathematical Model Illustrating Atherosclerotic Plaque Formation, 2020 Illinois State University

#### A Mathematical Model Illustrating Atherosclerotic Plaque Formation, Debasmita Mukherjee

*Annual Symposium on Biomathematics and Ecology Education and Research*

No abstract provided.