Border Inspections Of Imported Food And Related Products In Taiwan From 2011 To 2013,
2020
Taiwan Food and Drug Administration
Border Inspections Of Imported Food And Related Products In Taiwan From 2011 To 2013, H.-C. Chen, H.-L. Huang, S.-C. Chen, W.-L. Lu, C.-H. Tung, H.-W. Shiau, J.-Y. Wang, H.-W. Huang, J.-F. Shyu, R.-L. Feng, Y.-M. Chiang
Journal of Food and Drug Analysis
[No abstract available]
Antioxidant, Antimicrobial, Antitumor, And Cytotoxic Activities Of An Important Medicinal Plant (Euphorbia Royleana) From Pakistan,
2020
Taiwan Food and Drug Administration
Antioxidant, Antimicrobial, Antitumor, And Cytotoxic Activities Of An Important Medicinal Plant (Euphorbia Royleana) From Pakistan, A. Ashraf, R.A. Sarfraz, M.A. Rashid, M. Shahid
Journal of Food and Drug Analysis
The aim of present study was to evaluate antioxidant, antimicrobial, and antitumor activities of methanol, hexane, and aqueous extracts of fresh Euphorbia royleana. Total phenolic and flavonoid contents were estimated as gallic acid and querectin equivalents, respectively. Antioxidant activity was assessed by scavenging of free 2,2′- diphenyl-1-picrylhydrazyl radicals and reduction of ferric ions, and it was observed that inhibition values increase linearly with increase in concentration of extract. The results of ferric reducing antioxidant power assay showed that hexane extract has maximum ferric reducing power (12.70 ± 0.49 mg gallic acid equivalents/g of plant extract). Maximum phenolic (47.47 ± 0.71 …
High-Throughput Liquid Chromatography Tandem Mass Spectrometry Method For Simultaneous Determination Of Fampridine, Paroxetine, And Quinidine In Rat Plasma: Application To In Vivo Perfusion Study,
2020
Taiwan Food and Drug Administration
High-Throughput Liquid Chromatography Tandem Mass Spectrometry Method For Simultaneous Determination Of Fampridine, Paroxetine, And Quinidine In Rat Plasma: Application To In Vivo Perfusion Study, S. Achanti, R.R. Katta
Journal of Food and Drug Analysis
A selective and high-throughput liquid chromatography–mass spectrometry method has been developed and validated for the simultaneous quantification of paroxetine, fampridine, and quinidine in rat plasma using imipramine as an internal standard. Following protein precipitation extraction, the analytes and internal standard were run on XBridge C18 column (150 mm × 4.6 mm, 5 μm) using a gradient mobile phase consisting of 5mM ammonium formate in water (pH 9.0) and acetonitrile in a flow gradience program. The precursor and product ions of the drugs were monitored on a triple quadrupole instrument operated in the positive ionization mode. The method was validated over …
Nonenzymatic Glucose Sensor Based On Disposable Pencil Graphite Electrode Modified By Copper Nanoparticles,
2020
Taiwan Food and Drug Administration
Nonenzymatic Glucose Sensor Based On Disposable Pencil Graphite Electrode Modified By Copper Nanoparticles, S. Pourbeyram, K. Mehdizadeh
Journal of Food and Drug Analysis
A nonenzymatic glucose sensor based on a disposable pencil graphite electrode (PGE) modified by copper nanoparticles [Cu(NP)] was prepared for the first time. The prepared Cu(NP) exhibited an absorption peak centered at ∼562 nm using UV-visible spectrophotometry and an almost homogenous spherical shape by scanning electron microscopy. Cyclic voltammetry of Cu(NP)-PGE showed an adsorption controlled charge transfer process up to 90.0 mVs−1The sensor was applied for the determination of glucose using an amperometry technique with a detection limit of [0.44 (±0.01) μM] and concentration sensitivity of [1467.5 (±1.3) μA/mMcm−2]. The preparation of the Cu(NP)-PGE sensor was reproducible (relative standard deviation …
Antifatigue And Increasing Exercise Performance Of Actinidia Arguta Crude Alkaloids In Mice,
2020
Taiwan Food and Drug Administration
Antifatigue And Increasing Exercise Performance Of Actinidia Arguta Crude Alkaloids In Mice, Y. Liu, C. Liu
Journal of Food and Drug Analysis
Actinidia arguta (Siebold et Zucc.) Planch. ex. Miq. is one of the most recently domesticated fruit species with increasing commercial production worldwide. It is a well-known traditional Chinese medicine and is used to reduce blood glucose and treat atopic dermatitis. In addition, it possesses antioxidant, anticancer, and antiallergic properties. In this study, we investigated the physical antifatigue and exercise performance effects of A. arguta crude alkaloids (AACA) extracted with 70% ethanol. Four groups of male Kunming mice (n = 16) were orally administered AACA at doses of 0 mg/kg/d (vehicle), 50 mg/kg/d (AACA-50), 100 mg/kg/d (AACA-100), or 200 mg/kg/d (AACA-200) …
Production Of A Monoclonal Antibody Against Aflatoxin M1 And Its Application For Detection Of Aflatoxin M1 In Fortified Milk,
2020
Taiwan Food and Drug Administration
Production Of A Monoclonal Antibody Against Aflatoxin M1 And Its Application For Detection Of Aflatoxin M1 In Fortified Milk, U. Chadseesuwan, A. Sangdokmai, U. Pimpitak, S. Puthong, T. Palaga, K. Komolpis
Journal of Food and Drug Analysis
Aflatoxin M1 (AFM1) is a toxic metabolite of the fungal product aflatoxin found in milk. For food safety concern, maximum residual limits of AFM1 in milk and dairy products have been differently enforced in many countries. A suitable detection method is required to screen a large number of product samples for the AFM1 contamination. In this study, monoclonal antibodies (MAbs) against AFM1 were generated using a conventional somatic cell fusion technique. After screening, five MAbs (AFM1-1, AFM1-3, AFM1-9, AFM1-11, and AFM1-17) were obtained that showed cross-reactivity with aflatoxin B1 (AFB1) and aflatoxin G1 (AFG1) but with no other tested compounds. …
Hygienic Quality, Adulteration Of Pork And Histamine Production By Raoultella Ornithinolytica In Milkfish Dumpling,
2020
Taiwan Food and Drug Administration
Hygienic Quality, Adulteration Of Pork And Histamine Production By Raoultella Ornithinolytica In Milkfish Dumpling, Y.-C. Lee, Y.-F. Chen, Y.-L. Huang, H.-F. Kung, T.-Y. Chen, Y.-H. Tsai
Journal of Food and Drug Analysis
Ten milkfish dumpling products purchased from retail stores in southern Taiwan were collected to determine the occurrence of biogenic amines, histamine-forming bacteria, and adulteration of pork. This study showed the high contents of aerobic plate count (APC), total coliforms (TC) and Escherichia coli in tested milkfish dumpling samples, whereas the average content of various biogenic amines in all tested samples was < 1.6 mg/100 g (< 0.05 to 1.54 mg/100 g). Three histamine-producing bacterial strains (2 isolates of Raoultella ornithinolytica and 1 isolate of Enterobacter aerogenes) isolated from tested samples produced 276.6 ppm to 561.8 ppm of histamine in trypticase soy broth supplemented with 1.0% L-histidine (TSBH). Assay of multiplex polymerase chain reaction (PCR) revealed that the adulteration rates were 50% (5/10) for pork in milkfish dumplings. In addition, milkfish dumpling stuffing was inoculated with R. ornithinolytica at 5.0 log colony forming units (CFU)/g and stored at various temperatures from 4°C to 37°C to investigate bacterial growth and formation of histamine. The histamine contents quickly increased to higher than 50 mg/100 g in samples stored at 37°C and 25°C within 24 hours and 36 hours, respectively, as well as stored at 15°C within 48 hours. Therefore, bacterial growth and histamine formation were controlled by cold storage of the samples at 4°C. © 2016
Hydrolysis Of Isoflavone In Black Soy Milk Using Cellulose Bead As Enzyme Immobilizer,
2020
Taiwan Food and Drug Administration
Hydrolysis Of Isoflavone In Black Soy Milk Using Cellulose Bead As Enzyme Immobilizer, K.-I. Chen, Y. Yao, H.-J. Chen, Y.-C. Lo, R.-C. Yu, K.-C. Cheng
Journal of Food and Drug Analysis
The establishment of a catalytic system to enrich isoflavone aglycones in black soybean milk was investigated in this study. Beta-glucosidase, which was covalently immobilized onto cellulose beads, exhibited a significant efficiency for the conversion of 4-nitrophenyl β-D-glucuronide to p-nitrophenol over the sol–gel method. The Michaelis constant (Km) of the cellulose bead enzymatic system was determined to be 1.50 ± 0.10 mM. Operational reusability of the cellulose bead enzymatic system was justified for more than 10 batch reactions in black soy milk. Moreover, the storage stability verification indicated that the cellulose bead catalytic system was able to sustain its highest catalytic …
Characterization Of Yogurts Made With Milk Solids Nonfat By Rheological Behavior And Nuclear Magnetic Resonance Spectroscopy,
2020
Taiwan Food and Drug Administration
Characterization Of Yogurts Made With Milk Solids Nonfat By Rheological Behavior And Nuclear Magnetic Resonance Spectroscopy, H.-Y. Yu, L. Wang, K.L. Mccarthy
Journal of Food and Drug Analysis
The effect of adding milk solids nonfat (MSNF) on the physical properties and microstructure of yogurts was investigated. The physical properties of fat free yogurt, fat free with MSNF yogurt, whole fat yogurt, and whole fat with MSNF yogurt were analyzed using shear viscosity, viscoelasticity, and texture analysis. The two yogurts with MSNF had higher consistency coefficient (K), storage modulus (G′), yield stress, and hardness. To gain insight into the multiphase system, nuclear magnetic resonance (NMR) and brightfield microscope images were acquired. The addition of MSNF significantly modified NMR relaxation time; T1 values were reduced significantly. Brightfield microscope images showed …
Inhibitory Mechanism Against Oxidative Stress Of Caffeic Acid,
2020
Taiwan Food and Drug Administration
Inhibitory Mechanism Against Oxidative Stress Of Caffeic Acid, F.A. Khan, A. Maalik, G. Murtaza
Journal of Food and Drug Analysis
The purpose of this article is to summarize the reported antioxidant activities of a naturally abundant bioactive phenolic acid, caffeic acid (CA, 3,4-dihydroxycinnamic acid), so that new avenues for future research involving CA can be explored. CA is abundantly found in coffee, fruits, vegetables, oils, and tea. CA is among the most potential and abundantly found in nature, hydroxycinnamic acids with the potential of antioxidant behavior. Reactive oxygen species produced as a result of endogenous processes can lead to pathophysiological disturbances in the human body. Foods containing phenolic substances are a potential source for free radical scavenging; these chemicals are …
Proteomic Changes Associated With Metabolic Syndrome In A Fructose-Fed Rat Model,
2020
Taiwan Food and Drug Administration
Proteomic Changes Associated With Metabolic Syndrome In A Fructose-Fed Rat Model, C.-C. Hsieh, C.-C. Liao, Y.-C. Liao, L.S. Hwang, L.-Y. Wu, S.-C. Hsieh
Journal of Food and Drug Analysis
Metabolic syndrome (MetS), characterized by a constellation of disorders such as hyperglycemia, insulin resistance, and hypertension, is becoming a major global public health problem. Fructose consumption has increased dramatically over the past several decades and with it the incidence of MetS. However, its molecular mechanisms remain to be explored. In this study, we used male Sprague-Dawley (SD) rats to study the pathological mechanism of fructose induced MetS. The SD rats were fed a 60% high-fructose diet for 16 weeks to induce MetS. The induction of MetS was confirmed by blood biochemistry examination. Proteomics were used to investigate the differential hepatic …
Bovine Serum Albumin Adsorbed On Eremomycin And Grafted On Silica As New Mixed-Binary Chiral Sorbent For Improved Enantioseparation Of Drugs,
2020
Taiwan Food and Drug Administration
Bovine Serum Albumin Adsorbed On Eremomycin And Grafted On Silica As New Mixed-Binary Chiral Sorbent For Improved Enantioseparation Of Drugs, I.A. Fedorova, E.N. Shapovalova, O.A. Shpigun, S.M. Staroverov
Journal of Food and Drug Analysis
A new silica-based, mixed-binary chiral sorbent grafted with the macrocyclic antibiotic eremomycin and bovine serum albumin (BSA) was obtained. The sorbent-filled high-performance liquid chromatography column was capable of enantioseparation of racemic drugs, such as profens, in reversed-phase-chromatography mode. The mixed-binary eremomycin-BSA-sorbent showed better capability for profens enantioseparation as compared with a sorbent containing eremomycin only. BSA grafted onto the sorbent surface significantly reduced retention times of other proteins from the analyte solution, and free proteins (including BSA) injected as analytes were not retained on the column, and subsequently eluted with a dead volume. The drastic difference observed in the binding …
Antibacterial And Laxative Activities Of Strictinin Isolated From Pu'er Tea (Camellia Sinensis),
2020
Taiwan Food and Drug Administration
Antibacterial And Laxative Activities Of Strictinin Isolated From Pu'er Tea (Camellia Sinensis), S.-K. Hsieh, J.-R. Xu, N.-H. Lin, Y.-C. Li, G.-H. Chen, P.-C. Kuo, W.-Y. Chen, J.T.C. Tzen
Journal of Food and Drug Analysis
Strictinin, the major phenolic compound in Pu'er teas produced from young leaves and buds of wild trees, was isolated to evaluate its antibacterial and laxative activities. The minimum inhibitory concentrations of strictinin against Propionibacterium acnes and Staphylococcus epidermidis were determined as 250 μM and 2000 μM, respectively, apparently higher than those of several antibiotics commonly used for bacterial infections. The additive and synergistic effects on the inhibitory activities of strictinin combined with other commercial antibiotics were observed in two bacteria tested in this study via the analysis of fractional inhibitory concentrations. Laxative activity was observed on defecation of the rats …
Nanotechnology In Food Science: Functionality, Applicability, And Safety Assessment,
2020
Taiwan Food and Drug Administration
Nanotechnology In Food Science: Functionality, Applicability, And Safety Assessment, X. He, H.-M. Hwang
Journal of Food and Drug Analysis
Rapid development of nanotechnology is expected to transform many areas of food science and food industry with increasing investment and market share. In this article, current applications of nanotechnology in food systems are briefly reviewed. Functionality and applicability of food-related nanotechnology are highlighted in order to provide a comprehensive view on the development and safety assessment of nanotechnology in the food industry. While food nanotechnology offers great potential benefits, there are emerging concerns arising from its novel physicochemical properties. Therefore, the safety concerns and regulatory policies on its manufacturing, processing, packaging, and consumption are briefly addressed. At the end of …
Sedative And Hypnotic Effects Of Supercritical Carbon Dioxide Fluid Extraction From Schisandra Chinensis In Mice,
2020
Taiwan Food and Drug Administration
Sedative And Hypnotic Effects Of Supercritical Carbon Dioxide Fluid Extraction From Schisandra Chinensis In Mice, H. Zhu, L. Zhang, G. Wang, Z. He, Y. Zhao, Y. Xu, Y. Gao, L. Zhang
Journal of Food and Drug Analysis
Schisandra chinensis is a traditional Chinese medicine that has been used for treating insomnia and neurasthenia for centuries. Lignans, which are considered to be the bioactive components, are apt to be extracted by supercritical carbon dioxide. This study was conducted to investigate the sedative and hypnotic activities of the supercritical carbon dioxide fluid extraction of S. chinensis (SFES) in mice and the possible mechanisms. SFES exhibited an obvious sedative effect on shortening the locomotor activity in mice in a dose-dependent (10–200 mg/kg) manner. SFES (50 mg/kg, 100 mg/kg, and 200 mg/kg, intragstrically) showed a strong hypnotic effect in synergy with …
Composition Of Asarum Heterotropoides Var. Mandshuricum Radix Oil From Different Extraction Methods And Activities Against Human Body Odor-Producing Bacteria,
2020
Taiwan Food and Drug Administration
Composition Of Asarum Heterotropoides Var. Mandshuricum Radix Oil From Different Extraction Methods And Activities Against Human Body Odor-Producing Bacteria, A.S.M.T. Haque, J.N. Moon, P.S. Saravana, A. Tilahun, B.-S. Chun
Journal of Food and Drug Analysis
In this study, oils from Asarum heterotropoides were extracted by traditional solvent extraction and supercritical CO2 (SC-CO2) extraction methods and their antioxidant activities along with antimicrobial and inhibitory activities against five human body odor-producing bacteria (Staphylococcus epidermidis, Propionibacterium freudenreichii, Micrococcus luteus, Corynebacterium jeikeium, and Corynebacterium xerosis) were evaluated. The oil was found to contain 15 components, among which the most abundant component was methyl eugenol (37.6%), which was identified at every condition studied in different extraction methods. The oil extracted with n-hexane and ethanol mixture exhibited a strong antioxidant activity (92% ± 2%) and the highest ABTS and 2,2-diphenyl-1-picrylhydrazyl scavenging …
Investigation Of Aluminum Content Of Imported Candies And Snack Foods In Taiwan,
2020
Taiwan Food and Drug Administration
Investigation Of Aluminum Content Of Imported Candies And Snack Foods In Taiwan, T.S. Yeh, Y.-T. Liu, P.-J. Liou, H.-P. Li, C.-C. Chen
Journal of Food and Drug Analysis
Candies, chewing gums, dried fruits, jellies, chocolate, and shredded squid pieces imported from 17 countries were surveyed for their aluminum content. The samples were bought from candy shops, supermarkets, and convenience stores, and through online shopping. Sample selection focused on imported candies and snacks. A total of 67 samples, including five chewing gums, seven dried fruits, 13 chocolates, two jellies, two dried squid pieces, and 38 candies, were analyzed. The content of aluminum was analyzed by inductively coupled plasma optical emission spectrometry (ICP OES). The limit of quantitation for aluminum was 1.53 mg/kg. The content of aluminum ranged from not …
In Vitro Prebiotic Effects And Quantitative Analysis Of Bulnesia Sarmienti Extract,
2020
Taiwan Food and Drug Administration
In Vitro Prebiotic Effects And Quantitative Analysis Of Bulnesia Sarmienti Extract, M.A. Reza, M.A. Hossain, S.-J. Lee, J.-C. Kim, S.-C. Park
Journal of Food and Drug Analysis
Prebiotics are used to influence the growth, colonization, survival, and activity of probiotics, and enhance the innate immunity, thus improving the health status of the host. The survival, growth, and activity of probiotics are often interfered with by intrinsic factors and indigenous microbes in the gastrointestinal tract. In this study, Bulnesia sarmienti aqueous extract (BSAE) was evaluated for the growth-promoting activity of different strains of Lactobacillus acidophilus, and a simple, precise, cost-effective high-performance liquid chromatography (HPLC) method was developed and validated for the determination of active prebiotic ingredients in the extract. Different strains of L. acidophilus (probiotic) were incubated in …
Certification Of Caffeine Reference Material Purity By Ultraviolet/Visible Spectrophotometry And High-Performance Liquid Chromatography With Diode-Array Detection As Two Independent Analytical Methods,
2020
Taiwan Food and Drug Administration
Certification Of Caffeine Reference Material Purity By Ultraviolet/Visible Spectrophotometry And High-Performance Liquid Chromatography With Diode-Array Detection As Two Independent Analytical Methods, A.B. Shehata, M.S. Rizk, E.A. Rend
Journal of Food and Drug Analysis
Caffeine reference material certified for purity is produced worldwide, but no research work on the details of the certification process has been published in the literature. In this paper, we report the scientific details of the preparation and certification of pure caffeine reference materials. Caffeine was prepared by extraction from roasted and ground coffee by dichloromethane after heating in deionized water mixed with magnesium oxide. The extract was purified, dried, and bottled in dark glass vials. Stratified random selection was applied to select a number of vials for homogeneity and stability studies, which revealed that the prepared reference material is …
Green Synthesis Of Silver Nanoparticles Using Onion Extract And Their Application For The Preparation Of A Modified Electrode For Determination Of Ascorbic Acid,
2020
Taiwan Food and Drug Administration
Green Synthesis Of Silver Nanoparticles Using Onion Extract And Their Application For The Preparation Of A Modified Electrode For Determination Of Ascorbic Acid, M.A. Khalilzadeh, M. Borzoo
Journal of Food and Drug Analysis
A high-quality method for one-pot biosynthesis of silver nanoparticles (AgNPs) using onion extracts as reductant and stabilizer is reported. The synthesized AgNPs were characterized by ultraviolet-visible spectroscopy (UV-Vis), X-ray powder diffraction (XRD), and transmission electron microscopy (TEM). UV-Vis spectroscopy results showed that the AgNP absorption band was located at a peak of 397 nm in aqueous solution. Both XRD and TEM results confirmed that the AgNPs were mainly spherical with average diameters of 6.0 nm by TEM and about 5.3–10.2 nm calculated using XRD data. The ability of AgNPs to reduce charge transfer resistance was also investigated using electrochemical impedance …
