Medicinal Chemistry and Pharmaceutics Commons™

Open Access. Powered by Scholars. Published by Universities.™

9 Institutions 15 Full-Text Articles 24 Authors 2,855 Downloads

Recent Articles in Medicinal Chemistry and Pharmaceutics

Cure From The Cave: Volcanic Cave Actinomycetes And Their Potential In Drug Discovery, Naowarat (Ann) Cheeptham Dr., Tara Sadoway, Devon Rule, Kent Watson, Paul Moote, Laiel C. Soliman, Nicholas Azad, Kingsley Donkor, Derrick Horne University of South Florida

Cure From The Cave: Volcanic Cave Actinomycetes And Their Potential In Drug Discovery, Naowarat (Ann) Cheeptham Dr., Tara Sadoway, Devon Rule, Kent Watson, Paul Moote, Laiel C. Soliman, Nicholas Azad, Kingsley Donkor, Derrick Horne

International Journal of Speleology

Volcanic caves have been little studied for their potential as sources of novel microbial species and bioactive compounds with new scaffolds. We present the first study of volcanic cave microbiology from Canada and suggest that this habitat has great potential for the isolation of novel bioactive substances. Sample locations were plot ted on a contour map that was compiled in ArcView 3.2. Over 400 bacterial isolates were obtained from the Helmcken Falls cave in Wells Gray Provincial Park, British Columbia. From our preliminary screen, of 400 isolates tested, 1% showed activity against extended spectrum ß-lactamase E. coli, 1.75 ...

Go to article

Explore all content

Popular Institutions

Wayne State University

University of South Florida

Northeastern University

University of Pennsylvania

Based on downloads this month

Popular Authors

Devon Rule University of South Florida

Derrick Horne University of South Florida

Kingsley Donkor University of South Florida

Tara Sadoway University of South Florida

Nicholas Azad University of South Florida

Laiel Soliman University of South Florida

Kent Watson University of South Florida

Sun ea Choi Wayne State University

Naowarat (Ann) Cheeptham University of South Florida

Paul Moote University of South Florida

Based on downloads this month

Popular Articles

The Structural Requirements Of Histone Deacetylase (Hdac) Inhibitors: Suberoylanilide Hydroxamic Acid (Saha) Analogues Modified At C3, C6, And C7 Positions Enhance Selectivity, Sun ea Choi

Cure From The Cave: Volcanic Cave Actinomycetes And Their Potential In Drug Discovery, Tara Sadoway, Devon Rule, Kent Watson, Paul Moote, Laiel Soliman, Nicholas Azad, Kingsley Donkor, Derrick Horne, Naowarat (Ann) Cheeptham

Novel Inhibitors Of Lysine Specific Demethylase 1 As Epigenetic Modulators, Michael Crowley

Modulating The Pharmacokinetics Of Bioflavonoids, Adam Smith

The Application Of Proteomics Tools For Characterization Of Biopharmaceutical Processes

The Role Of 15-Lipoxygenase-1- And Cyclooxygenase-2-Derived Lipid Mediators In Endothelial Cell Proliferation, Cong Wei

Investigation Of The Absorptive Potential Of Polymeric Nanoparticles Across The Lungs And Their Development For Efficient Systemic Delivery Following Pulmonary Administration, Abdul khader Mohammad

La Flore Qui A Faim : Une Enquête Chimique, Biologique Et Culturelle De La Dimorphisme Rouge/Verte Et Les Applications Médicinales De Nepenthes Madagascariensis

The Reaction Of Methionine With A Non-C2-Symmetrical Platinum (Ii) Diamine Compound, Nilesh Sahi

Comparison Of Subcellular Responses For The Evaluation And Prediction Of The Chemotherapeutic Response To Cisplatin In Lung Adenocarcinoma Using Raman Spectroscopy, Aidan Meade, Fiona Lyng, Haq Nawaz, Franck Bonnier, Hugh Byrne

Based on downloads this month