Toxicology Commons

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Recent Articles in Toxicology

Exploring The Sulfide Tolerance Of Ectosymbiotic Niphargus Amphipods From The Frasassi Caves, Central Italy, Jan Bauermeister, Karoline Assig, Sharmishtha Dattagupta University of South Florida

Exploring The Sulfide Tolerance Of Ectosymbiotic Niphargus Amphipods From The Frasassi Caves, Central Italy, Jan Bauermeister, Karoline Assig, Sharmishtha Dattagupta

International Journal of Speleology

Two species of the crustacean amphipod genus Niphargus inhabit the sulfidic groundwaters of the Frasassi caves in central Italy, and both harbor filamentous, sulfide-oxidizing Thiothrix ectosymbionts. As sulfide is toxic to most aerobic organisms, it appeared possible that the ectosymbionts could help their Niphargus hosts with detoxification processes. In this study, mortality due to sulfide was compared between Niphargus individuals with ectosymbionts and individuals whose ectosymbionts had been killed by antibiotic treatment. Both Frasassi-dwelling Niphargus species revealed exceptionally high tolerances to sulfide compared to other amphipod species studied so far. Niphargus individuals without viable ectosymbionts tolerated sulfide levels exceeding those ...


Sp605-B Preventing Lead Poisioning, Martha Keel, Janice McCoy University of Tennessee, Knoxville

Sp605-B Preventing Lead Poisioning, Martha Keel, Janice Mccoy

Environment (Indoor & Outdoor)

No abstract provided.


Sp605-A What Do You Know About Lead Poisoning? Common Myths, Misunderstandings And The Facts, Martha Keel, Janice McCoy University of Tennessee, Knoxville

Sp605-A What Do You Know About Lead Poisoning? Common Myths, Misunderstandings And The Facts, Martha Keel, Janice Mccoy

Environment (Indoor & Outdoor)

No abstract provided.


Sp605-P Lead Poisoning Can Hurt Your Child Bookmark, Martha Keel University of Tennessee, Knoxville

Sp605-P Lead Poisoning Can Hurt Your Child Bookmark, Martha Keel

Environment (Indoor & Outdoor)

No abstract provided.


Non-Cytotoxic Antibacterial Silver–Coumarin Complex Doped Sol–Gel Coatings, Swarna Jaiswal, Brendan Duffy, Patrick McHale Dublin Institute of Technology

Non-Cytotoxic Antibacterial Silver–Coumarin Complex Doped Sol–Gel Coatings, Swarna Jaiswal, Brendan Duffy, Patrick Mchale

Articles

Microbial colonisation on clinical and industrial surfaces is currently of global concern and silane based sol–gel coatings are being proposed as potential solutions. Sol–gels are chemically inert, stable and homogeneous and can be designed to act as a reservoir for releasing antimicrobial agents over extended time periods. In the present study, silver nitrate (AgN) and a series of silver coumarin complexes based on coumarin-3-carboxylatosilver (AgC) and it is 6,7 and 8 hydroxylated analogues (Ag6, Ag7, Ag8) were incorporated into sol–gel coatings. The comparative antibacterial activity of the coatings was determined against meticillin resistant Staphylococcus aureus (MRSA ...


Reactive Oxygen Species Mediated Dna Damage In Human Lung Alveolar Epithelial (A549) Cells From Exposure To Non-Cytotoxic Mfi-Type Zeolite Nanoparticles, Kunal Bhattacharya, Pratap Naha, Izabela Naydenova, Svetlana Mintova, Hugh Byrne Dublin Institute of Technology

Reactive Oxygen Species Mediated Dna Damage In Human Lung Alveolar Epithelial (A549) Cells From Exposure To Non-Cytotoxic Mfi-Type Zeolite Nanoparticles, Kunal Bhattacharya, Pratap Naha, Izabela Naydenova, Svetlana Mintova, Hugh Byrne

Articles

Increasing utilization of engineered nanoparticles in the field of electronics and biomedical applications demands an assessment of risk associated with deliberate or accidental exposure. Metal based nanoparticles are potentially most important of all the nanoparticles in terms of health risks. Microporousalumino-silicates and pure silicates named as zeolites and zeo-type materials with variety of structures, chemical compositions, particle sizes and morphologies have a significant number of industrial uses such as in catalysis, sorption and ion-exchange processes. In particular, the nanosized particles due to their unique properties are used in hybrid organic-inorganic materials for photography, photonics, electronics, labeling, imaging, and sensing. The ...


Effects Of Salinity On The Toxicity Of Ionic Silver And Ag-Pvp Nanoparticles To Tisbe Battagliai And Ceramium Tenuicorne, Ailbhe Macken, Hugh Byrne, Kevin V. Thomas Dublin Institute of Technology

Effects Of Salinity On The Toxicity Of Ionic Silver And Ag-Pvp Nanoparticles To Tisbe Battagliai And Ceramium Tenuicorne, Ailbhe Macken, Hugh Byrne, Kevin V. Thomas

Articles

The toxic effects of polyvinylpyrrolidone (PVP) coated silver nanoparticles (Ag-NPPVP) and ionic Ag, to Tisbe battagliai (Tb) and Ceramium tenuicorne (Ct) were investigated and the usefulness of standardised marine guidelines for ENP risk assessment were assessed. The toxicity of Ag-NPPVP [CtEC50 = 26.6 µg/L, TbEC50 = 7.9 µg/L] and Ag+ [CtEC50 = 2312.2µg/L, Tb EC50 = 90.9 µg/L] to both test species differed, with the silver ENPs being more toxic. In contrast to Ag+ the toxicity of Ag-NPPVP increased significantly with increasing salinity, however, after thorough characterisation it was ...


Protecting Children From Overexposure To Lead In Candy And Protecting Children By Lowering The Blood Lead “Level Of Concern” Standard, Bryan Wagner, Colleen C. Hughes, Robert Sobsey University of Nevada, Las Vegas

Protecting Children From Overexposure To Lead In Candy And Protecting Children By Lowering The Blood Lead “Level Of Concern” Standard, Bryan Wagner, Colleen C. Hughes, Robert Sobsey

Nevada Journal of Public Health

The American Public Health Association: Recognizing that in April 2004, the Orange County Register in an investigative report, published for the first time information that the state of California had been testing for lead in candies for decades but had not informed the public about the high lead levels in many candies, candy wrappers and seasonings (sold as a snack item and consumed as candy) imported from Mexico, the Philippines and other countries.


Physiologically-Based Pharmacokinetic Modeling Of Acetaminophen Metabolism And Toxicity, David M. Ng, Ali Navid California Polytechnic State University

Physiologically-Based Pharmacokinetic Modeling Of Acetaminophen Metabolism And Toxicity, David M. Ng, Ali Navid

STEM Teacher and Researcher (STAR) Program Posters

Acetaminophen is a common analgesic and antipyretic. Metabolism of acetaminophen and acetaminophen-induced liver necrosis are predicted using physiologically-based pharmacokinetic (PBPK) modeling. Pharmacokinetic means the model determines where the drug is distributed in the body over time. Physiologically-based means the anatomy and physiology of the human body is reflected in the structure and functioning of the model. Acetaminophen is usually safe and effective when taken as recommended, but consumption at higher levels may lead to liver damage. Additionally, other factors such as alcoholic liver disease, smoking, and malnutrition affect the maximum safe dose of acetaminophen.


Warped Ideas: Geometric Morphometrics As A Complementary Technique For Studying Gastropod Shell Morphology, Mariam Yousif McMaster University

Warped Ideas: Geometric Morphometrics As A Complementary Technique For Studying Gastropod Shell Morphology, Mariam Yousif

Open Access Dissertations and Theses

Geometric morphometrics (GM) provides a complementary method for studying morphology. Snails have been analyzed in the field of morphometrics since the 1960s because their shells serve to record information about their life histories and environmental habitats. In this thesis, we present an annotated bibliography for advancements in GM, using applications to snail shells as a representative case study. We categorize 30 publications into four fields, morphology, ecology, taxonomy and evolution, and show that developments have been unequal among them. We conclude by predicting that GM applications on snail shells will increase, especially in hybrid fields, such as, ecotoxicology, which currently ...


Cadmium Accumulation And Distribution In Lettuce And Barley, Fardausi Akhter Western University

Cadmium Accumulation And Distribution In Lettuce And Barley, Fardausi Akhter

University of Western Ontario - Electronic Thesis and Dissertation Repository

Cadmium (Cd) is a non-essential trace element and its environmental concentrations are increasing due to human activities. Edible plants can accumulate high concentrations of Cd, which could be toxic to humans. Understanding how and where Cd is stored in plants is important for ensuring lower concentration of Cd in the food. In this thesis, the accumulation and distribution of Cd in three agricultural plants, namely lettuce (Lactuca sativa L.), barley (Hordeum vulgare L.) and radish (Raphanus sativus L.), were investigated with a focus on the potential mechanisms involved in the localization of Cd in the root. The main objectives of ...