Open Access. Powered by Scholars. Published by Universities.®
Skin and Connective Tissue Diseases Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (303)
- Dermatology (234)
- Anatomy (134)
- Integumentary System (118)
- Medical Sciences (47)
-
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (46)
- Life Sciences (38)
- Chemicals and Drugs (36)
- Neoplasms (30)
- Nursing (29)
- Immune System Diseases (26)
- Public Health (24)
- Rheumatology (23)
- Musculoskeletal Diseases (22)
- Oncology (22)
- Pathological Conditions, Signs and Symptoms (22)
- Diagnosis (21)
- Medical Education (21)
- Bacterial Infections and Mycoses (19)
- Pharmacy and Pharmaceutical Sciences (19)
- Therapeutics (17)
- Internal Medicine (16)
- Cell and Developmental Biology (15)
- Primary Care (14)
- Social and Behavioral Sciences (14)
- Health and Medical Administration (13)
- Cancer Biology (12)
- Institution
-
- Universitas Indonesia (119)
- HCA Healthcare (52)
- Selected Works (21)
- Philadelphia College of Osteopathic Medicine (18)
- Rowan University (18)
-
- Aga Khan University (15)
- Wayne State University (9)
- Western University (9)
- Children's Mercy Kansas City (8)
- Valparaiso University (8)
- Chapman University (7)
- Himmelfarb Health Sciences Library, The George Washington University (7)
- Otterbein University (7)
- LSU Health Science Center (6)
- Old Dominion University (6)
- Touro College and University System (6)
- University of Nebraska Medical Center (6)
- Ohio Northern University (5)
- The Texas Medical Center Library (5)
- Thomas Jefferson University (5)
- University of Texas Rio Grande Valley (5)
- University of Vermont (5)
- Edith Cowan University (4)
- University of North Dakota (4)
- Virginia Commonwealth University (4)
- Arcadia University (3)
- City University of New York (CUNY) (3)
- Dartmouth College (3)
- Liberty University (3)
- Marshall University (3)
- Keyword
-
- Melanoma (23)
- Dermatology (15)
- Psoriasis (14)
- Skin cancer (11)
- Diagnosis (9)
-
- Neoplasms (9)
- Acne vulgaris (8)
- Case Reports (8)
- Children (8)
- Fibrosis (8)
- Leprosy (8)
- Skin (8)
- Acne (7)
- Atopic dermatitis (7)
- Rheumatoid arthritis (7)
- Treatment (7)
- Basal cell carcinoma (6)
- Cancer (6)
- Dermoscopy (6)
- Humans (6)
- Rheumatology (6)
- Skin of color (6)
- Vitiligo (6)
- Wound healing (6)
- Erythema nodosum (5)
- Inflammation (5)
- Scleroderma (5)
- Animals (4)
- Carcinoma (4)
- Efficacy (4)
- Publication Year
- Publication
-
- Journal of General - Procedural Dermatology & Venereology Indonesia (116)
- PCOM Physician Assistant Studies Student Scholarship (17)
- Rowan-Virtua Research Day (15)
- HCA Healthcare Journal of Medicine (10)
- North Texas Research Forum 2024 (10)
-
- Electronic Thesis and Dissertation Repository (8)
- South Atlantic Division Research Day 2023 (8)
- West Florida Division Virtual Research Day 2020 (8)
- Journal of Mind and Medical Sciences (7)
- Nursing Student Class Projects (Formerly MSN) (7)
- Section of Internal Medicine (7)
- Ellen M. Gravallese (6)
- Posters (6)
- School of Medicine Faculty Publications (6)
- Clinical Research in Practice: The Journal of Team Hippocrates (5)
- Dermatology Faculty Publications (5)
- Dissertations & Theses (Open Access) (5)
- Graduate Medical Education Research Journal (5)
- Jonathan Kay (5)
- Pharmacy Faculty Articles and Research (5)
- Pharmacy and Wellness Review (5)
- Research Symposium (5)
- Honors Theses (4)
- Medical Student Research Symposium (4)
- North Texas Research Forum 2023 (4)
- Capstone Showcase (3)
- Department of Dermatology and Cutaneous Biology Faculty Papers (3)
- Department of Medicine (3)
- Family Medicine Clerkship Student Projects (3)
- NYMC Faculty Publications (3)
Articles 421 - 442 of 442
Full-Text Articles in Skin and Connective Tissue Diseases
Defining The Role Of Nras In Melanoma Maintenance, Sravya T. Challa, Sheri L. Holmen
Defining The Role Of Nras In Melanoma Maintenance, Sravya T. Challa, Sheri L. Holmen
Undergraduate Research Opportunities Program (UROP)
The incidence of melanoma has increased 600 percent over the last four decades; it is the most rapidly increasing malignancy among young people in the United States and is currently the leading cause of cancer death in women aged 25- 29. If detected early, the disease is easily treated; however, once the disease has metastasized it is largely refractory to conventional therapies and is associated with a high mortality rate. The development of cancer from a pre-malignant primary tumor to a metastatic cancer that develops at secondary sites is a multi-step process, thought to require many genetic and epigenetic events …
Mutant Cx43 In Skin Differentiation And Disease, Jared M. Churko
Mutant Cx43 In Skin Differentiation And Disease, Jared M. Churko
Electronic Thesis and Dissertation Repository
Connexin43 (Cx43) is expressed within keratinocytes, dermal fibroblasts, and the hair follicle epithelium. Since Cx43 is so widely expressed in resident cells of the skin, we speculated that this connexin would play an essential role in skin homeostasis, hair growth and wound healing. Mutations in the gene which encodes Cx43 lead to a disease called oculodentodigital dysplasia (ODDD) and patients expressing the frame-shift mutants (fs230 or fs260) develop a skin disease called palmar plantar hyperkeratosis. In addition, patients with ODDD often develop hair which is dry, sparse, and slow growing. To study skin abnormalities associated with ODDD, hair growth and …
Juvenile Dermatomyositis, Sidra Ishaque, Shakeel Ahmed, Rehan Ali, Khurram Minhas
Juvenile Dermatomyositis, Sidra Ishaque, Shakeel Ahmed, Rehan Ali, Khurram Minhas
Section of Internal Medicine
Juvenile dermatomyositis (JDM) is an important subtype of dermatomyositis characterized by inflammation of muscle, skin and gastrointestinal tract. A 14-year-old girl, with a history of fever, joint pain, easy fatigability and a rash since the age of 3 years is described. Physical examination, laboratory evaluation, electromyography (EMG) and muscle biopsy were suggestive of a chronic inflammatory process involving the muscles, most likely dermatomyositis. The report highlights the importance of a muscle biopsy as the gold standard for diagnosing dermatomyositis.
Antivirulence Potential Of Tr-700 And Clindamycin On Clinical Isolates Of Staphylococcus Aureus Producing Phenol-Soluble Modulins, Jason Yamaki, Timothy Synold, Annie Wong-Beringer
Antivirulence Potential Of Tr-700 And Clindamycin On Clinical Isolates Of Staphylococcus Aureus Producing Phenol-Soluble Modulins, Jason Yamaki, Timothy Synold, Annie Wong-Beringer
Pharmacy Faculty Articles and Research
Staphylococcus aureus strains (n = 50) causing complicated skin and skin structure infections produced various levels of phenol-soluble modulin alpha-type (PSMα) peptides; some produced more than twice that produced by the control strain (LAC USA300). TR-700 (oxazolidinone) and clindamycin strongly inhibited PSM production at one-half the MIC but exhibited weak to modest induction at one-fourth and one-eighth the MICs, primarily in low producers. Adequate dosing of these agents is emphasized to minimize the potential for paradoxical induction of virulence.
Análise Da Produção Bibliográfica Sobre Qualidade De Vida De Portadores De Feridas Crônicas / Bibliographical Analysis On Quality Of Life Of Patients With Chronic Wounds, Everton Alves, Edilson De Albuquerque
Análise Da Produção Bibliográfica Sobre Qualidade De Vida De Portadores De Feridas Crônicas / Bibliographical Analysis On Quality Of Life Of Patients With Chronic Wounds, Everton Alves, Edilson De Albuquerque
Everton Fernando Alves
O estudo teve como objeto analisar algumas características da produção bibliográfica sobre a Qualidade de Vida (QV) de portadores de Feridas Crônicas (FC) no Brasil entre 2000 e 2009. Para tanto, realizou-se uma revisão sistemática da literatura através da busca de estudos indexados nas bases de dados da BIREME. Os materiais encontrados e utilizados foram sete artigos, uma dissertação e uma tese. Destes, a maioria dos artigos se concentrou no ano de 2001 e 2006, correspondendo a 50% das publicações levantadas. Os resultados demonstraram que apenas uma publicação, ou seja, (16,6%) dos dados, foi encontrada na Revista Ciencia y Enfermería …
Dermoscopy: An Evidence-Based Approach For The Early Detection Of Melanoma, Angela Armstrong
Dermoscopy: An Evidence-Based Approach For The Early Detection Of Melanoma, Angela Armstrong
UNF Graduate Theses and Dissertations
The purpose of this project was to evaluate the effectiveness of a practice-based dermoscopy training program for dermatology healthcare providers in order to improve their technique of performing clinical skin exams for the early detection of melanomas.
The overall incidence of melanoma continues to rise. More than 75% of all skin cancer deaths are from melanoma. Advanced melanoma spreads to lymph nodes and internal organs and can result in death. One American dies from melanoma almost every hour (American Cancer Society [ACS], 2009). Early diagnosis and excision are essential to reduce morbidity and to improve patient survival.
This one-group before-and-after …
Is Monotherapy Treatment Of Etanercept Effective Against Plaque Psoriasis?, Joseph Devito
Is Monotherapy Treatment Of Etanercept Effective Against Plaque Psoriasis?, Joseph Devito
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this systematic review is to determine whether or not monotherapy treatment of etanercept is effective against plaque psoriasis.
Is The Use Of Narrowband Ultraviolet B (Nb-Uvb) Phototherapy Effective Monotherapy In The Treatment Of Adults With Plaque Psoriasis?, Andrea M. Cardine
Is The Use Of Narrowband Ultraviolet B (Nb-Uvb) Phototherapy Effective Monotherapy In The Treatment Of Adults With Plaque Psoriasis?, Andrea M. Cardine
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this systematic review is to determine whether or not narrowband ultraviolet B (NB-UVB) phototherapy is effective monotherapy in the treatment of adults with plaque psoriasis.
Is Alitretinoin (9-Cis-Retinoic Acid) Safe And Effective For Use In Hand Eczema?, Jeanne K. Seeberger
Is Alitretinoin (9-Cis-Retinoic Acid) Safe And Effective For Use In Hand Eczema?, Jeanne K. Seeberger
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: To determine if Alitretinoin is a safe and effective alternative to current treatments in reducing the symptoms of Hand Eczema (HE)
Is Topical 1% Pimecrolimus Cream An Effective Treatment For Rosacea?, Lauren Sloan
Is Topical 1% Pimecrolimus Cream An Effective Treatment For Rosacea?, Lauren Sloan
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this systematic review is to determine whether or not topical 1% pimecrolimus cream is an effective treatment for rosacea.
New Perspectives On Melanoma: The Role Of Pax3, Sandra Medic
New Perspectives On Melanoma: The Role Of Pax3, Sandra Medic
Theses: Doctorates and Masters
Background: Cutaneous melanoma is an aggressive form of skin cancer, arising in cutaneous melanocytes. The transcription factor PAX3 is critical for the proper development of neural crest lineages including melanocytes. Melanocytic cells show continued PAX3 expression from melanoblast formation in the neural crest to their differentiation into melanocytes. While many studies clarify the importance of PAX3 in embryonic development of melanocytes, less well understood, and more perplexing, is the continued PAX3 expression in adult skin melanocytes. By contrast PAX3 is frequently found in melanomas and naevi, and its expression correlates with melanoma staging. In this study we explore the multiple …
Plasmacytoid Dendritic Cells Sense Skin Injury And Promote Wound Healing Through Type I Interferons, Josh D. Gregorio
Plasmacytoid Dendritic Cells Sense Skin Injury And Promote Wound Healing Through Type I Interferons, Josh D. Gregorio
Dissertations & Theses (Open Access)
Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells, which selectively express intracellular Toll-like receptors (TLR)-7 and TLR-9 and have the capacity to produce large amounts of type I IFNs (IFN-a/b) in response to viruses or host derived nucleic acid containing complexes. pDCs are normally absent in skin but accumulate in the skin of psoriasis patients where their chronic activation to produce IFN-a/b drives the disease formation. Whether pDCs and their activation to produce IFN-a/b play a functional role in healthy skin is unknown. Here we show that pDCs are rapidly and transiently recruited into healthy human and …
Solar Radiation Damage To Human Skin Mitochondria, Luciene Zanchetta
Solar Radiation Damage To Human Skin Mitochondria, Luciene Zanchetta
Doctoral
The central objective of this study was to assess solar radiation-induced changes in cellular function, mitochondrial function and mitochondrial DNA to further investigate the role of these energy-dedicated and metabolically essential organelles in the response to the main environmental stressor associated with skin cancer initiation. An in vitro approach was chosen employing the human malignant melanoma (A375) and human amelanotic melanoma (C32) cells and the human spontaneously immortalized keratinocytes (HaCaT). A Q-Sun Solar Simulator was used to expose cells to low-level simulated solar radiation (SSR) as it provides a mimic of solar radiation that is environmentally relevant in the UV …
The Relationship Between Obesity And Skin And Soft Tissue Infections, Juliana Swiney
The Relationship Between Obesity And Skin And Soft Tissue Infections, Juliana Swiney
MPA/MPP/MPFM Capstone Projects
The Problem:
It is well known that our country is experiencing an obesity epidemic: 33.9% of all adults are obese (BMI>30) and 67% of adults are either overweight or obese (BMI>25). Obesity is a risk factor for several serious disease states such as, diabetes, stroke, hypertension, heart disease and some types of cancer. It also has a less well defined relationship with skin and soft tissue infections.
Although it is known that excessive weight increases the opportunity for harmful skin conditions, this relationship has not been as well studied. Some of the mechanisms that predispose obese people to …
Expression And Function Of Hypoxia Inducible Factor-1 Alpha In Human Melanoma Under Non-Hypoxic Conditions, Caroline N. Mills, Sandeep S. Joshi, Richard M. Niles
Expression And Function Of Hypoxia Inducible Factor-1 Alpha In Human Melanoma Under Non-Hypoxic Conditions, Caroline N. Mills, Sandeep S. Joshi, Richard M. Niles
Biochemistry and Microbiology
Background
Hypoxia inducible factor-1 alpha (HIF-1α) protein is rapidly degraded under normoxic conditions. When oxygen tensions fall HIF-1α protein stabilizes and transactivates genes involved in adaptation to hypoxic conditions. We have examined the normoxic expression of HIF-1α RNA and protein in normal human melanocytes and a series of human melanoma cell lines isolated from radial growth phase (RGP), vertical growth phase (VGP) and metastatic (MET) melanomas.
Results
HIF-1α mRNA and protein was increased in RGP vs melanocytes, VGP vs RGP and MET vs VGP melanoma cell lines. We also detected expression of a HIF-1α mRNA splice variant that lacks part …
John Contracts Skin Disease At Spa, Donna M. Hughes Dr., Melanie Shapiro Esq
John Contracts Skin Disease At Spa, Donna M. Hughes Dr., Melanie Shapiro Esq
Donna M. Hughes
Bleomycin Induced Pneumonitis: A Case Successfully Managed With High-Dose Steroids, Shahid Javed Husain, Ali Bin Sarwar Zubairi, Muhammad Irfan
Bleomycin Induced Pneumonitis: A Case Successfully Managed With High-Dose Steroids, Shahid Javed Husain, Ali Bin Sarwar Zubairi, Muhammad Irfan
Section of Pulmonary & Critical Care
No abstract provided.
Effects Of Retinoic Acid On Beta-Catenin Transcriptional Activity In Melanoma Cells, Fung Chan
Effects Of Retinoic Acid On Beta-Catenin Transcriptional Activity In Melanoma Cells, Fung Chan
Theses, Dissertations and Capstones
Melanoma is the most dangerous form of skin cancer and its incidence has been increasing in the United States. Most melanomas are resistant to current chemotherapies; therefore, understanding the mechanism of melanomagenesis is beneficial to treatment of the diseases. Accumulation of β-catenin has been shown in colon and other cancers, including melanomas, but the transcriptional role of β-catenin in melanomas is still unclear. All-trans retinoic acid (ATRA) is an anti-tumor agent that has an inhibitory effect on β-catenin, but this effect has not been studied in melanomas. It has been shown that Microphthalmia-associated transcription factor (MITF), a melanocyte specific protein, …
What Is The Safety And Efficacy Of Biobrane Versus Silver Sulfadiazine In The Treatment Of Low Body Surface Area Partial-Thickness Burns?, Gregory Wanner
What Is The Safety And Efficacy Of Biobrane Versus Silver Sulfadiazine In The Treatment Of Low Body Surface Area Partial-Thickness Burns?, Gregory Wanner
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: To determine how the synthetic skin substitute Biobrane compares to silver sulfadiazine (SSD, silvadine) in the treatment of patients with low body surface area partial thickness burns.
Reversible Nonthrombocytopenic Palpable Purpura Associated With Metoclopramide, Jeffery A. Goad
Reversible Nonthrombocytopenic Palpable Purpura Associated With Metoclopramide, Jeffery A. Goad
Pharmacy Faculty Articles and Research
OBJECTIVE: To report a case of reversible nonthrombocytopenic palpable purpura associated with metoclopramide.
CASE SUMMARY: A 72-year-old white man was admitted for worsening palpable purpura over a two-day period. Two days prior to admission, metoclopramide 10 mg orally three times per day was started for a gastrointestinal condition. Upon admission, all drugs were continued except metoclopramide. Over the next two days, the purpura began to resolve. Platelet count was within normal limits on admission and the patient developed no serious consequences because of the purpura.
DISCUSSION: According to the literature, reversible nonthrombocytopenic palpable purpura has not been …
Ua12/2/1 College Heights Herald, Vol. 72, No. 6, Wku Student Affairs
Ua12/2/1 College Heights Herald, Vol. 72, No. 6, Wku Student Affairs
WKU Archives Records
WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news.
Regular features include:
- Just a Second
- Campus Line
- For the Record / Crime Reports
- People Poll
- Sports
- Diversions
- Movie Reviews
- Classifieds
Articles in this issue:
- Stamper, John. Hurricane Fran
- VanWinkle, Cara. Bill Clinton Rules Favored – Tobacco
- Baker, Emily. Life With Diabetes is Bittersweet for Many Students
- VanWinkle, Cara. Olympics: Greek Pledges Keep Spirit Alive
- Signs of a World Becoming Less Humane
- Browning, Michelle. Cancer: Protect Yourself from Harmful Rays
- Hall, Jason. Board of Regents Get Frowns, Stars from Students
- Simmons, Darryn. Purpose of Armed Services Questioned
- Miller, Kristen. …
The Effect Of Fetal Age On Skin Permeability In Guinea Pigs, Benita Stiles Whitted
The Effect Of Fetal Age On Skin Permeability In Guinea Pigs, Benita Stiles Whitted
Loma Linda University Electronic Theses, Dissertations & Projects
Preliminary investigation has indicated large decreases in fetal skin permeability during the latter half of gestation (Parmley and Seeds, 1970; Treager, 1966). The purpose of this study was to demonstrate the degree of skin permeability in fetal guinea pigs at various gestational stages. The test hypothesis was that these skins would show a significant decrease in permeability to tritiated water when tested at time increments through out the latter half of gestation.
In vitro skin permeability to tritiated water was measured in samples from 22 guinea pig fetuses. Gestational age ranged from 30 to 65 days in increments of five, …