Artificial Intelligence and Robotics Commons^™

A Survey On Deep Learning For Drug-Target Binding Prediction: Models, Benchmarks, Evaluation, And Case Studies, Kusal Debnath, Pratip Rana, Preetam Ghosh

Computer Science Faculty Publications

Conventional drug discovery is expensive, time-consuming, and prone to failure. Artificial intelligence has become a potent substitute over the last decade, providing strong answers to challenging biological issues in this field. Among these difficulties, drug-target binding (DTB) is a key component of drug discovery techniques. In this context, drug-target affinity and drug–target interaction are complementary and essential frameworks that work together to improve our comprehension of DTB dynamics. In this work, we thoroughly analyze the most recent deep learning models, popular benchmark datasets, and assessment metrics for DTB prediction. We look at the paradigm shift in the development of drug …

Normalizing Images In Various Weather And Lighting Conditions Using Colorpix2pix Generative Adversarial Network, Sanjida Tasnim, Ashif Mahmud Mostafa, Azmain Morshed, Namreen Shaiyaz, Shakib Mahmud Dipto, Saad Aloteibi, Mohammad Ali Moni, Md. Golam Rabiul Alam, Md. Ashraful Alam

Computer Science Faculty Publications

Autonomous vehicles (AVs) are widely regarded as the future of transportation due to their tremendous benefits and user comfort. However, the AVs have been struggling with very crucial challenges, such as achieving reliable accuracy in object detection as well as faster computation required for quick decision-making. In recent years, perception systems in driverless cars have been significantly enhanced, mainly due to advances in deep-learning-based object detection systems. However, these perception systems are still heavily affected by environmental variables, such as changes in illumination, refractive interference, and adverse weather conditions, which may compromise their reliability and safety. This research proposes an …

Coldstartcpi: Induced-Fit Theory-Guided Dti Predictive Model With Improved Generalization Performance, Qichang Zhao, Haochen Zhao, Linyuan Gao, Kai Zheng, Yajie Li, Qiao Ling, Jing Tang, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Predicting compound-protein interactions (CPIs) plays a crucial role in drug discovery. Traditional methods, based on the key-lock theory and rigid docking, often fail with novel compounds and proteins due to their inability to account for molecular flexibility and the high sparsity of CPI data. Here, we introduce ColdstartCPI, a framework inspired by induced-fit theory, which leverages unsupervised pre-training features and a Transformer module to learn both compound and protein characteristics. ColdstartCPI treats proteins and compounds as flexible molecules during inference, aligning with biological insights. It outperforms state-of-the-art sequence-based models, particularly for unseen compounds and proteins, and shows strong generalization capability …

Geometric Gnns For Charged Particle Tracking At Gluex, Ahmed Hossam Mohammed, Kishansingh Rajput, Simon Taylor, Denis Furletov, Sergey Furletov, Malachi Schram

Computer Science Faculty Publications

Nuclear physics experiments are aimed at uncovering the fundamental building blocks of matter. The experiments involve high-energy collisions that produce complex events with many particle trajectories. Tracking charged particles resulting from collisions in the presence of a strong magnetic field is critical to enable the reconstruction of particle trajectories and precise determination of interactions. It is traditionally achieved through combinatorial approaches that scale worse than linearly as the number of hits grows. Since particle hit data naturally form a point cloud and can be structured as graphs, graph neural networks (GNNs) emerge as an intuitive and effective choice for this …

Adapting Online Customer Reviews For Blind Users: A Case Study Of Restaurant Reviews, Mohan Sunkara, Akshay Kolgar Nayak, Sandeep Kalari, Yash Prakash, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Online reviews have become an integral aspect of consumer decision-making on e-commerce websites, especially in the restaurant industry. Unlike sighted users who can visually skim through the reviews, perusing reviews remains challenging for blind users, who rely on screen reader assistive technology that supports predominantly one-dimensional narration of content via keyboard shortcuts. In an interview study, we uncovered numerous pain points of blind screen reader users with online restaurant reviews, notably, the listening fatigue and frustration after going through only the first few reviews. To address these issues, we developed QuickCue assistive tool that performs aspect-focused sentiment-driven summarization to reorganize …

Decode The Workload: Training Deep Learning Models For Efficient Compute Cluster Representation, Ahmed Hossam Mohammed, Mark Jones, Diana Mcspadden, Malachi Schram, Bryan Hess, Kishansingh Rajput

Computer Science Faculty Publications

In this study, we address the mounting challenge of monitoring high throughput computing clusters running computationally intensive jobs, which increasingly strains system administrators. We develop autoencoders that analyze traces of Linux kernel CPU metrics to capture salient system features by producing robust compressed embeddings for various downstream tasks. In addition, we employ graph neural networks to incorporate contextual information from surrounding CPUs and assess their performance. We also demonstrate the enhanced job differentiation achieved by increasing the sampling rate of these traces. Our models are evaluated based on their ability to generate meaningful latent representations, detect anomalies, and distinguish between …

Neural Topic Modeling Via Contextual And Graph Information Fusion, Jiyuan Liu, Jiaxing Yan, Chunjiang Zhu, Xingyu Liu, Qing Li, Yanghui Rao

Computer Science Faculty Publications

Topic modeling is a powerful unsupervised tool for knowledge discovery. However, existing work struggles with generating limited-quality topics that are uninformative and incoherent, which hindering interpretable insights from managing textual data. In this paper, we improve the original variational autoencoder framework by incorporating contextual and graph information to address the above issues. First, the encoder utilizes topic fusion techniques to combine contextual and bag-of-words information well, and meanwhile exploits the constraints of topic alignment and topic sharpening to generate informative topics. Second, we develop a simple word co-occurrence graph information fusion strategy that efficiently increases topic coherence. On three benchmark …

Adversarially Attacking Graph Properties And Sparsification In Graph Learning, Chunjiang Zhu, Blake Gaines, Jing Deng, Jinbo Bi

Computer Science Faculty Publications

Graph neural networks and graph transformers explicitly or implicitly rely on fundamental properties of the underlying graph, such as spectral properties and shortest-path distances. However, it is still not clear how these graph properties are vulnerable to adversarial attacks and what impacts this has on the downstream graph learning. Moreover, while graph sparsification has been used to improve computational cost of learning over graphs, its susceptibility to adversarial attacks has not been studied. In this paper, we study adversarial attacks on graph properties and graph sparsification and their impacts on downstream graph learning, paving the way for how to protect …

A Personal Interview With William Patry: His Thoughts On Music, Ai, And Copyright

IP Theory

No abstract provided.

Csc36000 - Modern Distributed Computing Assignment 2, Saptarashmi Bandyopadhyay

Open Educational Resources

This assignment is designed to help the student identify and mitigate common errors in Distributed Computing such as race conditions and reaching consensus, as well as reflecting on how Distributed Computing concepts apply to their class project.

Design And Analysis Of Facial Recognition Algorithms For Home Monitoring, Nathaniel F. Bernich

Honors Theses and Capstones

Facial recognition "in the wild" has posed a challenge in the field of computer vision. Though facial recognition algorithms are generally proficient at recognizing faces up close, subjects at awkward angles and greater distances from the camera make monitoring areas with this software a practical challenge. At UNH's Cognitive Assistive Robotics Lab (CARL), overcoming the weak areas of face recognition is essential to the task of home monitoring. The CARL research team is implementing a suite of robotics and computer vision technologies to monitor patients with Alzheimer's dementia in their homes. This necessitates a reliable and effective facial recognition pipeline …

Application Of Machine Learning And Large Language Models In Healthcare For Data Prediction And Summarization, Chiazam Chisom Izuchukwu

College of Graduate Studies: Theses & Dissertations

This study aims to examine the use of machine learning (ML) and large language models (LLMs) in healthcare to enhance disease prediction, clinical decision-making, and information management. Five supervised ML models—Logistic Regression (LR), Support Vector Machine (SVM), Random Forest (RF), Decision Trees (DT), and Naïve Bayes (NB)—on three different computing platforms—Google Colab, Databricks, and Snowflake—were employed for disease classification. Data preprocessing included treating missing values, encoding categorical variables utilizing one-hot-encoding, feature scaling when needed, and tackling class imbalance with Synthetic Minority Over-sampling Technique (SMOTE) before an 80-20 train-test separation. Models were created with Scikit-learn (Google Collab), Spark MLlib (Databricks), and …

Comparative Analysis Of Eye-Metric Algorithms For Code Comprehension In Introductory Cs Course, Noushin Gauhar

College of Graduate Studies: Theses & Dissertations

Eye-tracking technology offers a non-intrusive way to study cognitive processes by tracking where and how long individuals look. In computer science education, it provides valuable insights into how students understand source code—a task that requires intense visual and mental effort. This study investigates how eye-tracking can reveal differences in code comprehension strategies among students in an Introductory Programming course. By analyzing three key metrics—dwell time, gaze entropy, and the K coefficient—the research explores how students engage with code. Dwell time indicates cognitive focus on specific code elements, the K coefficient measures attentional shifts between scanning and focused reading, and gaze …

Fault And Cyberattack Diagnosis And Handling Via Large Language Models And State Prediction For Manufacturing And Quantum Systems, Jihan Abou Halloun

Wayne State University Dissertations

In the digitalization era and Smart Manufacturing, companies are harnessing the power of artificial intelligence (AI) and machine learning (ML) across multiple sectors, including process engineering optimization, process control and fault detection, to enhance efficiency and engineering decision making. Although AI and ML are widely used in anomaly detection and handling, there are still areas where it has been less explored. One of the major areas where AI’s potential in manufacturing needs to be characterized is with respect to the applications of large language models (LLMs) in manufacturing troubleshooting for fault/attack handling. A second major area where the potential of …

How Do Selected Biomedical And Health Sciences Journals React To Submissions Of Artificial Intelligence (Ai) Assisted Manuscripts?, Misa Mi, Lin Wu, Yingting Zhang, Wendy Wu

Library Scholarly Publications

Background and Objectives: Generative artificial intelligence (GenAI) increasingly impacts research and scholarly communication. Given the evolving application of ChatGPT and other AI tools in scholarly communications, health sciences librarians must become cognizant of any existing journal publishing guidelines for AI-created or assisted manuscripts. The study aims to examine how scholarly biomedical and health sciences journals and publishers respond to submissions of these manuscripts and what requirements or policies have been put in place to guide and instruct authors on AI use.

Methods: We first retrieved and consolidated a list of journals representing disciplines in biomedical and health sciences from four …

Machine Learning Models For Pancreatic Cancer Survival Prediction: A Multi-Model Analysis Across Stages And Treatments Using The Surveillance, Epidemiology, And End Results (Seer) Database, Aditya Chakraborty, Mohan D. Pant

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background: Pancreatic cancer is among the most lethal malignancies, with poor prognosis and limited survival despite treatment advances. Accurate survival modeling is critical for prognostication and clinical decision-making. This study had three primary aims: (1) to determine the best-fitting survival distribution among patients diagnosed and deceased from pancreatic cancer across stages and treatment types; (2) to construct and compare predictive risk classification models; and (3) to evaluate survival probabilities using parametric, semi-parametric, non-parametric, machine learning, and deep learning methods for Stage IV patients receiving both chemotherapy and radiation. Methods: Using data from the SEER database, parametric models (Generalized Extreme Value, …

Understanding Physiological Responses For Intelligent Posture Detection Using Wearable Technology, Chaitanya Vardhini Anumula, Tanvi Banerjee, Anuradha Oak

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

This study investigates the physiological impact of Iyengar yoga at the pose-level using EmbracePlus wearable smartwatch, for data recording and personalized yoga pose detection for tracking.

A Two-Phase Learning Approach Integrated With Multi-Source Features For Cloud Service Qos Prediction, Fuzan Chen, Jing Yang, Haiyang Feng, Harris Wu, Minqiang Li

Information Technology & Decision Sciences Faculty Publications

Quality of Service (QoS) is a key factor for users when choosing cloud services. However, QoS values are often unavailable due to insufficient user evaluations or provider data. To address this, we propose a new QoS prediction method, Multi-source Feature Two-phase Learning (MFTL). MFTL incorporates multiple sources of features influencing QoS and uses a two-phase learning framework to make effective use of these features. In the first phase, coarse-grained learning is performed using a neighborhood-integrated matrix factorization model, along with a strategy for selecting high-quality neighbors for target users. In the second phase, reinforcement learning through a deep neural network …

A Spoofing Speech Detection Method Combining Multi-Scale Features And Cross-Layer Identification, Hongyan Yuan, Linjuan Zhang, Baoning Niu, Xianrong Zheng

Information Technology & Decision Sciences Faculty Publications

Pre-trained self-supervised speech models can extract general acoustic features, providing feature inputs for various speech downstream tasks. Spoofing speech detection, which is a pressing issue in the age of generative AI, requires both global information and local features of speech. The multi-layer transformer structure in pre-trained speech models can effectively capture temporal information and global context in speech, but there is still room for improvement in handling local features. To address this issue, a speech spoofing detection method that integrates multi-scale features and cross-layer information is proposed. The method introduces a multi-scale feature adapter (MSFA), which enhances the model’s ability …

Investing In The Age Of Generative Ai: A Gpt-Based Sentiment Analysis Approach, Xianrong Zheng

Information Technology & Decision Sciences Faculty Publications

Generative AI, which ushers a new age of AI, comes with huge economic potential. To capitalize the AI boom, investors are interested in trading AI stocks. AI chatbots, which can identify and classify the sentiment from financial news, can be leveraged for investment. So, this paper proposes a GPT-based sentiment analysis approach for trading AI stocks. Also, natural experiments are conducted to evaluate its effectiveness. Initial results show that the approach achieves a good rate of return.