Epidemiology Commons^™

Exercise To Improve Asthma Control And Lung Function In Stable Asthma: An Evidence-Based Case Report, Abdul Rois Romdhon, Andre Thadeo Abraham, Triya Damayanti

Kesmas

Asthma is a heterogeneous disease with respiratory symptoms that vary over time and intensity. Exercise-induced asthma patients are advised to avoid strenuous physical activity, which can trigger bronchospasm. However, appropriate exercise can improve asthma control and lung function in stable asthma patients. A literature search was conducted on PubMed, COCHRANE, and EMBASE databases using Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines according to the specified eligibility criteria. Those studies were critically appraised using the Oxford Critical Appraisal Tool 4.0. Four articles were selected based on the PRISMA search strategy flowchart to assess their validity, importance, and applicability. …

Multidrug-Resistant Organisms Infection On Mortality Of Burn Patients At Public Hospital X In Jakarta: A Retrospective Study, Raja Merlinda Veronica, July Kumalawati, Cleopas Martin Rumende, Leonard Nainggolan, Marcellus Simadibrata, Hamzah Shatri, Em Yunir, Aditya Wardhana, Erni Juwita Nelwan, Musfardi Rustam

Kesmas

Susceptibility to infection and increasing antibiotic resistance put burn patients at risk of developing infections caused by multidrug-resistant organisms (MDRO). This condition can progress to sepsis, increasing morbidity and mortality. This retrospective cohort study employed the medical record data of patients treated at Public Hospital X in Jakarta, Indonesia, from January 2020 to June 2022. Of 160 subjects, most were aged <60 years (82.5%) and had comorbidities (16.88%). The most common cause of burns was fire (86.25%). The use of medical devices was 90.63%, with a 14-day median length of stay. The most common gram-negative MDRO pathogens were K. pneumoniae (29.91%), Enterobacter sp (22.32%), and Acinetobacter (20.54%); 45% of patients infected with MDRO died. The bivariate analysis found an increased risk of death due to MDRO infection in burn patients (RR 1.103; 95%CI 1.004-1.211, p-value = 0.046). After adjusting for role variables (age, comorbidities, total body surface area, use of medical devices, length of stay) and from multivariate analysis, the confounding variables for MDRO infection and mortality were length of stay and age. MDRO infection increases the mortality rate in burn patients. Mortality in burn patients due to MDRO infection is greater than non-MDRO.

Data Mining Analysis With Orange In The Development Of Tuberculosis Among Diabetes Mellitus Patients, Malahayati Rusli Bintang, Adang Bachtiar, Cicilya Candi

Kesmas

Prevention and treatment of diabetes will have a positive influence on tuberculosis (TB) since people may get TB because they have diabetes mellitus (DM). Recording and reporting through the TB Information System are not run optimally because of many factors. The information system must be strengthened to be used by private health facilities. This study used secondary data from the 2013 and 2018 Indonesian Basic Health Research (IBHR). The data was analyzed univariately and analyzed further using Orange Data Mining Tools to test the screening tool model used to predict TB in diabetic individuals. The total sample in this study …

New Approach To Mapping Regional Vulnerability In Controlling Tuberculosis Disease In Indonesia, Maria Holly Herawati, Asep Hermawan, Dasuki Dasuki, Hadi Supratikta, Al Asyary, M Rokhis Khomarudin, Muhammad Priyatna, Raflizar Raflizar, Kristina Kristina, Noer Endah Pracoyo, Dina Bisara, Cahya Tri Purnami, Mentari Nur Farida Suteja, Yusrial Bachtiar, Noor Edi Widya Sukoco, Doni Lasut

Kesmas

Tuberculosis (TB) in Indonesia is still a health problem. The TB prevalence in Indonesia ranks second in the world after India in 2023. Regional factors, inadequate healthcare facilities, and limited resources (financial, human, and infrastructure) are challenges requiring innovation to help the government control TB. TB eradication efforts need to be made with a comprehensive and effective approach. One method used is to look at the vast territory of Indonesia, therefore, mapping the TB disease vulnerability is a highly recommended method. The use of a Geographic Information System is expected to help map the TB vulnerability areas in Indonesia. Given …

Ammonia Exposure Based On The Length Of Work To Lung Function Abnormalities Among Traditional Scavengers, Maulyda Shakeela Jasmine, Fajaria Nurcandra, Nayla Kamilia Fithri, Arga Buntara

Kesmas

Lung function abnormalities can be caused by smoking habits or air pollution. Sanitary landfills can produce ammonia, which can cause lung function abnormalities. This study aimed to determine a relationship between ammonia exposure based on the length of work and lung function abnormalities among traditional scavengers at the Sumur Batu Landfill, Bekasi City, West Java Province, Indonesia. This analytical observational study applied quantitative methods and cross-sectional design. A total of 85 scavengers were selected using purposive sampling from March to May 2023. Data was obtained using a respondent characteristics questionnaire, spirometry, and spectrophotometer and analyzed using the Cox Regression Model. …

Smoking Habit At Home And Upper Respiratory Infection In Infants Aged 6-12 Months, Musfardi Rustam, Nur Pelita Sembiring, Taswir Effendy

Kesmas

Upper Respiratory Tract Infection (URI) is an acute infection caused by viruses, fungi, and bacteria. Smoking habit at home is a risk factor for URI in infants. This study aimed to determine a relationship between smoking at home and the incidence of URI in infants. This study was conducted the fourth week of February 2010 until the third week of April 2010 in Kampar District, Indonesia. This analytical study used a case-control design and cluster random sampling. The samples comprised 162 cases and 162 controls, infants aged 6-12 months. The cases were 162 infants aged 6-12 months suffering from URI …

A Mixed Methods Exploration Of Young Women's Agency And Mental Health During Covid-19 In Low-Income Communities In Mumbai, India, Marie A Brault, Melissa F Peskin, Anastasia N Jones, Amrita Saikia, Rinchen O Bhutia, Sai Sammitha Cheruvu, Vaishali M Jagtap, Rajendra Singh, Poornima Nair, Rajesh Vedanthan, Sten H Vermund, Shubhada Maitra

Faculty, Staff and Student Publications

Introduction: Adolescent girls and young women (AGYW) in India face additional health inequities compared to their male peers, as gender norms constrain agency for prevention and self-care. The onset of the COVID-19 pandemic and associated lockdowns deepened health inequities and often worsened mental health, but the impacts on agency are unclear. This exploratory sequential mixed methods paper examined mental health and COVID-19 elements that exacerbated or mitigated adverse consequences for AGYW in low-income communities in Mumbai.

Methods: We conducted semi-structured interviews with AGYW (aged 15-25 years; N = 60) and adults (parents, healthcare providers, community-based organization representative; N = 30). …

Sociocultural Effects On Suicidal Ideation Among South Asian Immigrants, Rezwana Ahmed Choudhury

Walden Dissertations and Doctoral Studies

With the growing South Asian immigrant population in the West, it is necessary to conduct suicide-related studies among this population to understand the reasons behind suicidal ideation faced by this population. This quantitative cross-sectional survey design study aimed to examine sociocultural factors that may be associated to the risk level of suicidal ideation among South Asian immigrants in the United States. A survey questionnaire was developed using a combination of demographic questions and existing instruments: the Suicide Ideation Attributes Scale, Religious Belief Salience Scale, Suinn-Lew Asian Self-Identity Acculturation Scale, and Rapid Eating Assessment for Participants—S. Data were collected from a …

Bayesian Beta-Binomial Mixed Models For Longitudinal, Clustered, And Spatiotemporal Data, Chun-Che Wen

MUSC Theses and Dissertations

Overdispersed binomial data arise in many clinical and public health research studies. Examples include timeline followback data (TLFB), which are used in addiction research to monitor recent substance use. This dissertation proposes novel beta-binomial (BB) mixed models to address the challenges associated with overdispersed binomial data, including zero-inflation, heterogenous effects, and spatiotemporal correlation. Motivated by a 12-week randomized controlled trial evaluating the efficacy of varenicline tartrate for smoking cessation among adolescents, Aim 1 develops a Bayesian zero-inflated beta-binomial (ZIBB) model to analyze longitudinal and bounded TLFB data — namely, the number of abstinent days in the past week. Because treatment …

Impact Of A Pharmacist-Led Hcv Treatment Program At A Federally Qualified Health Center, Jerika T. Lam, Sharon Xavioer

Pharmacy Faculty Articles and Research

Pharmacists are key players who can help to eliminate the hepatitis C virus (HCV) epidemic in the United States. This pilot retrospective study evaluated the impact of a pharmacist-led HCV treatment program in a federally qualified health center (FQHC) primary care clinic setting. The primary outcome was to assess sustained virologic response (SVR) rates 12 weeks after patients were initiated and completed their oral direct acting antiviral (DAA) treatment regimens. Methods: This pilot retrospective study included historical analyses of patients who received DAA treatment in the pharmacist-led HCV treatment program in a FQHC clinic between 1 January 2019 and 31 …

Psychological Impact Of Ebola Disease On Survivors: A West Africa Study, Babatunde Moses Irinoye

Walden Dissertations and Doctoral Studies

Survivors of Ebola virus disease often experience social isolation. Understanding the psychological impact of Ebola virus disease on these survivors was the focus of this study. The study encompasses assessment of experiences in re-integration back into communities, and psychological implications (post-recovery), among Ebola infection survivors (EIS) in Republic of Liberia. The purpose of the study was to explore the psychological impact of Ebola as the EIS continue their re-integration journey in their communities in Liberia. The conceptual framework for this study was based on principles of system theory, based on interrelatedness of the biopsychological experience of the EIS, and the …

Association Of High Fibrinogen To Albumin Ratio With Long-Term Mortality In Patients With Spontaneous Intracerebral Hemorrhage, Shiping Chen, Yu Zhang, Yangchun Xiao, Xin Cheng, Liyuan Peng, Yixin Tian, Tiangui Li, Jialing He, Pengfei Hao, Weelic Chong, Yang Hai, Chao You, Fang Fang

Department of Medical Oncology Faculty Papers

BACKGROUND: The association between fibrinogen-to-albumin ratio (FAR) and in-hospital mortality in patients with spontaneous intracerebral hemorrhage (ICH) has been established. However, the association with long-term mortality in spontaneous ICH remains unclear. This study aims to investigate the association between FAR and long-term mortality in these patients.

METHODS: Our retrospective study involved 3,538 patients who were diagnosed with ICH at West China Hospital, Sichuan University. All serum fibrinogen and serum albumin samples were collected within 24 h of admission and participants were divided into two groups according to the FAR. We conducted a Cox proportional hazard analysis to evaluate the association …

Relationship Between Geographic Location, Race, And Socioeconomic Status On Adolescent Male Hpv Vaccination In The United States, Stacy Herb

Walden Dissertations and Doctoral Studies

Human papillomavirus (HPV) represents the most prevalent sexually transmitted infection in the United States. Despite readily available safe and effective vaccines and established knowledge of influencing factors, HPV vaccination rates in the United States remain suboptimal, particularly among adolescent males. This quantitative study addressed this gap by investigating the association between geographic location, race, and socioeconomic status with HPV vaccination uptake in adolescent males. A secondary data analysis was conducted using the 2022 National Immunization Survey (NIS)—Teen, comprised of 22,667 adolescent males. The fundamental cause theory served as the theoretical framework, guiding the exploration of why a safe and effective …

The Role Of Sexual Network Core Groups In Disease Epidemics, Jason Janeaux

LSU Doctoral Dissertations

Sexually transmitted infections (STIs) remain an economic and social burden, non-discriminately affecting sexually active individuals worldwide. The unique transmission of STIs is dependent upon host and pathogen life histories, as well as the underlying network structure of the host population. Within a population there is a group of individuals, the core group, that maintains STI presence and helps sustain ongoing transmission both within the core group and in the surrounding population. While the presence of these core groups is well documented, the criteria for inclusion into a sexual core group is not. In this dissertation, I explore common factors that …

An Epidemiological Study Of Tinea Corporis In Al-Najaf City, Ahmed Rashad Rasool, Amel Mustafa Kamil, Dhakam Mohammed Abbas

Maaen Journal for Medical Sciences

Background: Dermatophytes are humans' and animals' primary causative agents in charge of cutaneous fungal infections. Understanding the epidemic behavior of dermatophytosis, such as Tinea corporis, which specifically affects the trunk, neck, and extremities, might aid in its prevention. Aim of the study: The study aims to determine the proportion of Tinea corporis and dermatophytosis, the clinical type distribution of dermatophytosis, and participant demographics for Tinea corporis. Method: a cross-sectional study focuses on individuals diagnosed with Tinea corporis in the three general hospitals in Al-Najaf City the study takes place from April 1st to July 31st. all cases with tinea corporis …

Childhood Sexual Abuse And Compulsive Sexual Behavior Among Men Who Have Sex With Men Newly Diagnosed With Hiv, Monique J. Brown, Medinat Omobola Osinubi, Daniel Amoatika, Mohammad Rifat Haider, Sally Kirklewski, Patrick Wilson, Nathan B. Hansen

Faculty Publications

Childhood sexual abuse (CSA) continues to be a public health challenge. The prevalence of experiencing CSA is higher among men who have sex with men (MSM) than the general population. CSA has been linked to compulsive sexual behavior (CSB) among varying populations but has not been examined among MSM who were newly diagnosed with HIV. Therefore, the aims of this study were to assess the direct association between CSA and CSB among newly diagnosed MSM living with HIV, and to identify the potential mediating roles of depressive symptoms and emotion regulation in the association between CSA and CSB. The study …

Perceived Stress, Social Media Usage, And Sleep Quality In United States Adults, Justine P. Scott

Walden Dissertations and Doctoral Studies

The purpose of this quantitative study was to explore the intricate connections among perceived stress, sleep quality, and social media usage metrics, challenging prior assumptions by highlighting social media as a noteworthy stress coping mechanism. The research aimed to understand the relationship between sleep quality, perceived stress, and the frequency and quality of social media use, guided by the biopsychosocial model as the theoretical framework.The study involved adults aged 20-65. A questionnaire incorporated four validated instruments to assess these variables: the Epworth Sleepiness Scale (ESS), Internet Addiction Diagnostic Questionnaire (IADQ), Perceived Stress Scale (PSS), and Social Media Quality Measure (SMQM). …

Socioeconomic Status On The Management Of Type-2 Diabetes Among African Americans (Aged 26–64) In Rural Pennsylvania, Mariejo Joyce Constant

Walden Dissertations and Doctoral Studies

There is a lack of knowledge on hardly-reached patients’ socioeconomic status (SES). This quantitative study examined the extent to which SES moderated or impacted the relationships of African American status, rural status, or insurance status with type-2 diabetes mellitus (T2DM) management outcomes (testing for elevated glucose levels, patient education, and regular doctor visits) for African American individuals of low SES living in rural areas. The theoretical foundation for this study was the ecological systems theory (EST). Secondary data were from the publicly available Behavioral Risk Factor Surveillance System (BRFSS) 2021 dataset. Binary and linear regression analyses showed insufficient results to …

The Protective Efficacy Of A Sars-Cov-2 Vaccine Candidate B1351v Against Several Variant Challenges In K18-Hace2 Mice, Jie Yang, Huifen Fan, Anna Yang, Wenhui Wang, Xin Wan, Fengjie Lin, Dongsheng Yang, Jie Wu, Kaiwen Wang, Wei Li, Qian Cai, Lei You, Deqin Pang, Jia Lu, Changfu Guo, Jinrong Shi, Yan Sun, Xinguo Li, Kai Duan, Shuo Shen, Shengli Meng, Jing Guo, Zejun Wang

Faculty, Staff and Student Publications

The emergence of SARS-CoV-2 variants of concern (VOCs) with increased transmissibility and partial resistance to neutralization by antibodies has been observed globally. There is an urgent need for an effective vaccine to combat these variants. Our study demonstrated that the B.1.351 variant inactivated vaccine candidate (B.1.351V) generated strong binding and neutralizing antibody responses in BALB/c mice against the B.1.351 virus and other SARS-CoV-2 variants after two doses within 28 days. Immunized K18-hACE2 mice also exhibited elevated levels of live virus-neutralizing antibodies against various SARS-CoV-2 viruses. Following infection with these viruses, K18-hACE2 mice displayed a stable body weight, a high survival …

Knowledge, Attitudes And Practices Regarding Sexually Transmitted Infections In South Carolina: A Cross-Sectional Survey And Comparison To Geographically-Associated Social Determinants Of Health, Sean Patrick Sweeney

Theses and Dissertations

Sexually transmitted disease (STD) rates are on the rise in the United States. South Carolina ranks consistently among the states with the highest STD burdens, especially for the bacterial diseases gonorrhea and chlamydia. This study sought to determine the opinions, beliefs, and knowledgebase of South Carolina citizens regarding STDs and sexual health/education. In doing so, the study seeks to identify areas of improvement for educators, healthcare workers, and public health employees. Using a web-based cross-sectional survey, this study contacted approximately 900,000 South Carolina residents for participation. Participants were asked a variety of questions focused on STD knowledge, opinions, and practices. …