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The Epidemiology Of Clostridioides Difficile In Nebraska - A Descriptive Study Between 2018-2020, Storm Keffer 2021 University of Nebraska Medical Center

The Epidemiology Of Clostridioides Difficile In Nebraska - A Descriptive Study Between 2018-2020, Storm Keffer

Capstone Experience

Objectives: Clostridioides difficile (C. diff) is a common but challenging infection both financially and medically. Due to these difficulties, Clostridioides difficile infection (CDI) caused by C. diff is a mandatory reportable disease in Nebraska and as such has been a priority disease targeted by various disease control practices across many hospitals. All CDI laboratory results are reported electronically through the Nebraska Electronic Disease Surveillance System (NEDSS). However, capturing and conceptualizing the true burden of CDIs in Nebraska has not been adequately accomplished since monitoring of CDIs began. The objective of this study is to examine the trends of C. diff ...


The Effect Of Fiber And Omega-6:Omega-3 Fatty Acid Ratio On Asthma And Asthma-Related Symptoms In An Adult U.S. Population, Korie AS Nelson 2021 University of Nebraska Medical College

The Effect Of Fiber And Omega-6:Omega-3 Fatty Acid Ratio On Asthma And Asthma-Related Symptoms In An Adult U.S. Population, Korie As Nelson

Capstone Experience

Asthma is one of the most common diseases in the world affecting more than 10% of adults in many westernized countries and 339 million globally. Studies have shown a positive association between increased dietary fiber and improvement in asthma-related inflammation. Omega-3 fatty acids have also been shown to help mitigate inflammation in general. No identified studies have looked at the synergistic effect of omega-3 and omega-6 fatty acids alone and as a ratio with fiber on asthma, lung function, and respiratory morbidities. A positive association could mean that dietary interventions of fiber and fatty acids could significantly improve asthma and ...


Adherence To Mediterranean Diet Among Adolescents Attending Public Schools In North Lebanon, Rosy Mitri, Fouad Ziade 2021 Rosi Mitri, Assistant Professor, Faculty of Health Sciences, Beirut Arab University, Beirut, Lebanon

Adherence To Mediterranean Diet Among Adolescents Attending Public Schools In North Lebanon, Rosy Mitri, Fouad Ziade

BAU Journal - Health and Wellbeing

The Mediterranean diet (MD) is a model of a healthy diet and healthy lifestyle. Adherence to the MD has been correlated with a reduction in many metabolic disorders including cancers. The factors associated with adolescents’ adherence to the MD in North Lebanon using the KIDMED index have never been explored. The objective of this study was to examine the factors associated with the Mediterranean diet (MD) adherence among a sample of Lebanese adolescents. A cross-sectional survey was conducted in the city of Tripoli, North Lebanon. A total of 298 students, aged 11-18 years, were randomly selected from public schools in ...


A Cross-Sectional Study On Bullying And Psychological Disturbances Among Malaysian School Children, Muhammad Lokman Md Isa, Nurfatin Aina Mocktar, Wisam Nabeel Ibrahim, Mohd Said Nurumal, Muhammad Kamil Che Hasan 2021 Kulliyyah of Nursing, International Islamic University Malaysia, Kuantan 25200, Malaysia

A Cross-Sectional Study On Bullying And Psychological Disturbances Among Malaysian School Children, Muhammad Lokman Md Isa, Nurfatin Aina Mocktar, Wisam Nabeel Ibrahim, Mohd Said Nurumal, Muhammad Kamil Che Hasan

Makara Journal of Health Research

Background: Bullying is a common violence in school and has become a major public health and global concern. Bullying influences mental health and is identified as a leading factor of depression. Therefore, this study aimed to identify bullying prevalence and its association toward psychological disturbances (stress, anxiety, and depression).

Methods: This cross-sectional study was conducted in three secondary schools in Kuantan. After obtaining consent from parents/guardians, participants were asked to answer a self-administered questionnaire, including School Climate Bullying Survey, Depression Anxiety Stress Questionnaire-21, Patient Depression Questionnaire, and Generalized Anxiety Disorder. Demographic data were self-reported. Data were analyzed using SPSS ...


Effects Of Ectodermal Dysplasia On The Maxilla: A Study Of Cone-Beam Computed Tomography, Beyza Karadede Ünal 2021 Department of Orthodontics, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir 35640, Turkey

Effects Of Ectodermal Dysplasia On The Maxilla: A Study Of Cone-Beam Computed Tomography, Beyza Karadede Ünal

Makara Journal of Health Research

Background: This study aimed to examine the effects of ectodermal dysplasia (ED) on the transverse width of the maxillary bone.

Methods: The ED group was composed of seven people, while the control group consisted of retrospective cone-beam computed tomography images of seven individuals with skeletal class 1 relationship. Images on the sagittal planes were taken, and cross-sections were taken from the longest point of the Anterior Nasal Spine-Posterior Nasal Spine line. The distance between the distal anterior canine teeth from the right buccal cortical bone to the left buccal cortical bone was measured. At the posterior region, the distance between ...


Controlling Dentistry-Related Musculoskeletal Disorders With Ergonomic Interventions In Lahore, Pakistan, Marriyam Nasar, Farwa Rubab, Hazik Bin Shahzad, Minam Qureshi, Maham Shahid, Pakiza Batool 2021 Institute of Social and Cultural Studies, University of the Punjab, Lahore 54590, Pakistan

Controlling Dentistry-Related Musculoskeletal Disorders With Ergonomic Interventions In Lahore, Pakistan, Marriyam Nasar, Farwa Rubab, Hazik Bin Shahzad, Minam Qureshi, Maham Shahid, Pakiza Batool

Makara Journal of Health Research

Background: Musculoskeletal disorders (MSDs) usually result from a prolonged static position and repetitive movements. A comfortable environment, appropriate working position, and multiple short breaks could alleviate MSDs. While the occasional back or neck ache is not a cause for alarm, regularly occurring pain or discomfort, if ignored, may further develop into an injury or career-ending disability.

Methods: A total of 370 dentists were selected from two dental hospitals and multiple dental clinics in Lahore, Pakistan. Current MSDs were recorded with the Standardized Nordic Questionnaire (SNQ). Information sheets containing dental ergonomics and back and tendon-gliding exercises were distributed among the participants ...


Prevalence And Impacts Of Musculoskeletal Pain Among The Elderly Living In The East Coast Region Of Peninsular Malaysia, Muhammad Kamil Che Hasan, Nur Nabila Izzati Asmera, Suliza Sulaiman, Mohd Said Nurumal, Nik Noor Kaussar Nik Mohd Hatta 2021 Kulliyyah of Nursing, International Islamic University Malaysia, Kuantan 25200, Malaysia

Prevalence And Impacts Of Musculoskeletal Pain Among The Elderly Living In The East Coast Region Of Peninsular Malaysia, Muhammad Kamil Che Hasan, Nur Nabila Izzati Asmera, Suliza Sulaiman, Mohd Said Nurumal, Nik Noor Kaussar Nik Mohd Hatta

Makara Journal of Health Research

Background: Musculoskeletal pain commonly affects the elderly, but the extent of this problem within the Malaysian community remains unknown. This study aimed to investigate the prevalence and impact of musculoskeletal pain among the elderly living in the community.

Methods: Elderly individuals aged 60 years and above with musculoskeletal pain and intact cognition were recruited for this study. Musculoskeletal pain was scored using the Nordic Musculoskeletal Questionnaire, and functional ability was assessed via the Lawton Instrumental Activities of Daily Living scale. Mental wellbeing was evaluated using the Short Warwick–Edinburgh Mental Wellbeing scale, and risk of falling was determined via the ...


Prevalence And Associated Factors Of Urinary Incontinence Among Elderly In Pekanbaru, Indonesia, Wulan Sari 2021 Public Health Program, STIKes Hang Tuah Pekanbaru, Pekanbaru 28281, Indonesia

Prevalence And Associated Factors Of Urinary Incontinence Among Elderly In Pekanbaru, Indonesia, Wulan Sari

Makara Journal of Health Research

Background: The proportion of the elderly in Riau Province was 4.8% higher than that (4.2%) in 2011. Urinary incontinence (UI) is a common health problem among the elderly. This study aims to determine the prevalence and associated factors for UI among the elderly (≥60 years).

Methods: This cross-sectional study was conducted in 20 public health centers in Pekanbaru City in 2018. A total of 351 elderly meeting the inclusion criteria were enrolled. Gender, age, education, occupation, marital status, obesity, depression, cognitive impairment, smoking status, history of chronic cough, and history of lower abdominal surgery served as the independent ...


Determinants Of Postnatal Care Service Utilization In Indonesia: A Secondary Analysis Using The Indonesian Health And Demographics Survey, Haerawati Idris, Willyana Syafriyanti 2021 Faculty of Public Health, Sriwijaya University, South Sumatera 30862, Indonesia

Determinants Of Postnatal Care Service Utilization In Indonesia: A Secondary Analysis Using The Indonesian Health And Demographics Survey, Haerawati Idris, Willyana Syafriyanti

Makara Journal of Health Research

Background: The postnatal complication that occurs in the first week after childbirth is one of the causes of maternal death in Indonesia. However, it can be prevented with postnatal care (PNC). This study aims to analyze the determinants of PNC service utilization in Indonesia.

Methods: This quantitative study employed a cross-sectional study design and used secondary data from the Indonesian Health and Demographics Survey of 2017. The sample consisted of 14,724 women aged 15–49 years. We assessed the predictors of PNC service utilization using multivariate logistic regression models.

Results: About 78.4% of the respondents utilized PNC services ...


Soft Drink Consumption Patterns Of Middle School Students In North Okkalarpa, Moh Moh Thwe, Sein Yaw May, Min Htike Aung 2021 Department of Community Health Nursing, University of Nursing, Yangon 11131, Myanmar

Soft Drink Consumption Patterns Of Middle School Students In North Okkalarpa, Moh Moh Thwe, Sein Yaw May, Min Htike Aung

Makara Journal of Health Research

Background: Urbanization and economic development in Myanmar have brought about culture and dietary transition from a traditional to a westernized diet. The health of the nation, especially the youth, may influence the changing dietary patterns: i.e., the higher the soft drink consumption, the higher the prevalence of soft drink-related diseases.

Methods: This cross-sectional study was carried out among 250 middle school students in North Okkalarpa Township, Yangon Region. Data were collected using self-structured questionnaires, and respondents were selected by using simple random sampling method.

Results: In this study, 81.2% of the students consumed soft drink once a day ...


Mothers’ Nutritional Knowledge, Self-Efficacy, And Practice Of Meal Preparation For School-Age Children In Yangon, Myanmar, Wut Yee Phyo, Ohn Khin Khin, Min Htike Aung 2021 Department of Community Health Nursing, University of Nursing, Yangon 11131, Myanmar

Mothers’ Nutritional Knowledge, Self-Efficacy, And Practice Of Meal Preparation For School-Age Children In Yangon, Myanmar, Wut Yee Phyo, Ohn Khin Khin, Min Htike Aung

Makara Journal of Health Research

Background: Childhood malnutrition is a global public health concern. For Myanmar, mothers play a prominent role in improving the nutritional status of children as they prepare meals for children.

Methods: This community-based cross-sectional analytical study was conducted on 367 mother-child pairs (6–10 years). Significantly, systematic random sampling and structured questionnaires were utilized in this study.

Results: The mean age of mothers was 35.73 ± 6.9 years, and a majority had fair nutritional knowledge (52.3%), good self-efficacy (79.8%), and good practice of meal preparation (59.4%). The prevalence of childhood malnutrition was categorized as stunting (18.2 ...


Epigenome-Wide Association Study Of Kidney Function Identifies Trans-Ethnic And Ethnic-Specific Loci, Charles E. Breeze, Anna Batorsky, Mi Kyeong Lee, Mindy D. Szeto, Xiaoguang Xu, Daniel L. McCartney, Rong Jiang, Amit Patki, Holly J. Kramer, James M. Eales, Laura Raffield, Leslie Lange, Ethan Lange, Peter Durda, Yongmei Liu, Russ P. Tracy, David Van Den Berg, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed MESA Multi-Omics Working Group, Kathryn L. Evans, William E. Kraus, Donna K. Arnett 2021 National Cancer Institute

Epigenome-Wide Association Study Of Kidney Function Identifies Trans-Ethnic And Ethnic-Specific Loci, Charles E. Breeze, Anna Batorsky, Mi Kyeong Lee, Mindy D. Szeto, Xiaoguang Xu, Daniel L. Mccartney, Rong Jiang, Amit Patki, Holly J. Kramer, James M. Eales, Laura Raffield, Leslie Lange, Ethan Lange, Peter Durda, Yongmei Liu, Russ P. Tracy, David Van Den Berg, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Topmed Mesa Multi-Omics Working Group, Kathryn L. Evans, William E. Kraus, Donna K. Arnett

Epidemiology Faculty Publications

BACKGROUND: DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this are poorly understood. We aimed to identify trans-ethnic and ethnic-specific differentially methylated positions (DMPs) associated with eGFR using an agnostic, genome-wide approach.

METHODS: The study included up to 5428 participants from multi-ethnic studies for discovery and 8109 participants for replication. We tested the associations between whole blood DNAm and eGFR using beta values from Illumina 450K or EPIC arrays. Ethnicity-stratified analyses were performed using linear ...


Bridging The Inequality Gap Among Marginalized Populations In Africa Amid The Covid-19 Pandemic: A Call For Responsible Cooperation, Aanuoluwapo A. Afolabi, Olayinka S. Ilesanmi Dr., Titilope A. Afolabi 2021 Department of Community Medicine, College of Medicine, University of Ibadan, Ibadan, n=Nigeria

Bridging The Inequality Gap Among Marginalized Populations In Africa Amid The Covid-19 Pandemic: A Call For Responsible Cooperation, Aanuoluwapo A. Afolabi, Olayinka S. Ilesanmi Dr., Titilope A. Afolabi

The University of Louisville Journal of Respiratory Infections

No abstract provided.


Current Trends In The Application Of Causal Inference Methods To Pooled Longitudinal Observational Infectious Disease Studies-A Protocol For A Methodological Systematic Review, Heather Hufstedler, Ellicott C. Matthay, Sabahat Rahman, Valentijn M. T. de Jong, Harlan Campbell, Paul Gustafson, Thomas Debray, Thomas Jaenisch, Lauren Maxwell, Till Barnighausen 2021 Heidelberg University

Current Trends In The Application Of Causal Inference Methods To Pooled Longitudinal Observational Infectious Disease Studies-A Protocol For A Methodological Systematic Review, Heather Hufstedler, Ellicott C. Matthay, Sabahat Rahman, Valentijn M. T. De Jong, Harlan Campbell, Paul Gustafson, Thomas Debray, Thomas Jaenisch, Lauren Maxwell, Till Barnighausen

COVID-19 Publications by UMMS Authors

INTRODUCTION: Pooling (or combining) and analysing observational, longitudinal data at the individual level facilitates inference through increased sample sizes, allowing for joint estimation of study- and individual-level exposure variables, and better enabling the assessment of rare exposures and diseases. Empirical studies leveraging such methods when randomization is unethical or impractical have grown in the health sciences in recent years. The adoption of so-called "causal" methods to account for both/either measured and/or unmeasured confounders is an important addition to the methodological toolkit for understanding the distribution, progression, and consequences of infectious diseases (IDs) and interventions on IDs. In the ...


Suppression Of Human Coronavirus 229e Infection In Lung Fibroblast Cells Via Rna Interference, Hamidreza Montazeri Aliabadi, Jennifer Totonchy, Parvin Mahdipoor, Keykavous Parang, Hasan Uludağ 2021 Chapman University

Suppression Of Human Coronavirus 229e Infection In Lung Fibroblast Cells Via Rna Interference, Hamidreza Montazeri Aliabadi, Jennifer Totonchy, Parvin Mahdipoor, Keykavous Parang, Hasan Uludağ

Pharmacy Faculty Articles and Research

Despite extensive efforts to repurpose approved drugs, discover new small molecules, and develop vaccines, COVID-19 pandemic is still claiming victims around the world. The current arsenal of antiviral compounds did not perform well in the past viral infections (e.g., SARS), which casts a shadow of doubt for use against the new SARS-CoV-2. Vaccines should offer the ultimate protection; however, there is limited information about the longevity of the generated immunity and the protection against possible mutations. This study uses Human Coronavirus 229E as a model coronavirus to test the hypothesis that effective delivery of virus-specific siRNAs to infected cells ...


Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram 2021 University of Louisville

Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram

The University of Louisville Journal of Respiratory Infections

Streptococcus milleri group (SMG) also referred to as the Streptococcus anginosus group. These are Gram-positive, variable hemolysis, catalase negative, microaerophilic, non-motile facultative anaerobes which have been known to cause abscesses in humans. We report a case of empyema caused by Streptococcus anginosus in a patient with an unresolved pneumonia for over a month. In early October 2018, the patient presented to an emergency room with the complaints of shortness of air, productive cough, chills, subjective fever and weight loss for 4 weeks. A chest X-ray revealed a left lower lobe pneumonia. He was treated with 250 mg of azithromycin for ...


Characteristics And Outcomes Of Bacteremic Pneumococcal Pneumonia Of Patients With And Without Hiv Infection In Argentina, Alejandra González 2021 Posadas Hospital

Characteristics And Outcomes Of Bacteremic Pneumococcal Pneumonia Of Patients With And Without Hiv Infection In Argentina, Alejandra González

The University of Louisville Journal of Respiratory Infections

Streptococcus pneumoniae is the main causative agent of pneumonia, with a 10 to 25 percent rate of isolation in blood cultures. Controversies exist regarding the prognostic impact of a history of human immunodeficiency virus (HIV) infection on community-acquired pneumonia.

The aim of our work was to analyze and compare the clinical presentation, radiological findings and progression of pneumococcal pneumonia in patients infected with and not infected with HIV. We retrospectively analyzed adult patients with positive blood cultures for Streptococcus pneumoniae and clinical and radiological findings compatible with pneumonia in the period between January 2012 and May 2017. Age, sex, comorbidities ...


Announcing Plans For Fall 2021, Cedarville University 2021 Cedarville University

Announcing Plans For Fall 2021, Cedarville University

COVID-19 Updates

No abstract provided.


Seroprevalence Of Sars-Cov-2 Antibody In Echocardiography And Stress Laboratory, Renuka Jain, Stacie Kroboth, Denise Ignatowski, Bijoy K. Khandheria 2021 Advocate Aurora Health

Seroprevalence Of Sars-Cov-2 Antibody In Echocardiography And Stress Laboratory, Renuka Jain, Stacie Kroboth, Denise Ignatowski, Bijoy K. Khandheria

Journal of Patient-Centered Research and Reviews

Purpose: Transesophageal echocardiography is an aerosol-generating procedure, and exercise stress testing is a potentially aerosol-generating activity. Concern has been raised about heightened risk of transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among health care personnel participating in these procedures. We aimed to investigate the prevalence of past coronavirus disease 2019 (COVID-19) infection in echocardiography and stress laboratory staff.

Methods: All staff who worked in the echocardiography and stress laboratories of one high-traffic urban hospital from March 15, 2020, to June 15, 2020, were asked to voluntarily participate. Those willing to participate were consented, and past COVID-19 infection was ...


Preprocedure Covid-19 Testing In Early Phase Of Pandemic, Renuka Jain, Bradley Kruger, Robert Citronberg, Stacie Kroboth, Ana Cristina Perez Moreno, Bijoy K. Khandheria 2021 Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke’s Medical Centers

Preprocedure Covid-19 Testing In Early Phase Of Pandemic, Renuka Jain, Bradley Kruger, Robert Citronberg, Stacie Kroboth, Ana Cristina Perez Moreno, Bijoy K. Khandheria

Journal of Patient-Centered Research and Reviews

The COVID-19 pandemic led to a nationwide shutdown of elective medical procedures. Upon resumption of services, preprocedure nasopharyngeal swab testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was introduced for all patients requiring surgical or other aerosol-generating procedures. We investigated preprocedure COVID-19 testing in one of the largest U.S. health systems. Patients included in this retrospective, observational study were asymptomatic and scheduled for a procedure or surgery. All patients underwent a nasopharyngeal swab test for SARS-CoV-2 performed 24–72 hours prior to a planned procedure. Clinical demographics, type of procedure, test results, and subsequent procedure status were evaluated ...


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