Epidemiology Commons^™

Correlates And Predictors Of Risky Sexual Partnering, Jennifer Nield

Theses and Dissertations

Introduction: Sexually Transmitted Diseases, including HIV/AIDS, continue to be a major burden in the United States. Sexual partnering behaviors contribute to the spread of STDs. Sexual concurrency has been shown to exponentially increase STD prevalence in populations. Serial monogamy with short periods between sexual partners also introduces risk. Methods: We identified sexually active men and women from the 2006-2010 National Survey of Family Growth (NSFG) and used sub sets for each particular study. Sexual partnering was defined as being concurrent, serially monogamous or monogamous in the previous year. Polytomous logistic regression models were developed to evaluate the associations between age …

The Association Of Caregivers' Educational Level And Their Knowledge Of Children's Nutrition And Exercise Behavior, Hauwa Okorie, Bersabeh Medmim, Nazrat Mirza

GW Research Days 2013

BACKGROUND:

Parents play an instrumental role in modeling their children's health behaviors and exposing them to new foods, and engaging them in physical activities.

OBJECTIVE:

To assess the association of parents' educational level on their nutritional and physical activity knowledge.

METHODS:

This is a cross-sectional study of 72 participants from a nutrition and wellness program targeting parents of African American preschoolers. Socio-demographic, child's nutritional and physical exercise habit survey and anthropometric data were collected from all participants at baseline.

RESULTS:

77% of the participants were grandmothers or mothers; the mean age was 44.8 and 13% of participants were college graduates. …

Occupational Exposure To Ultraviolet Radiation And Risk Of Non-Melanoma Skin Cancer In A Multinational European Study, Simona Surdu, Edward F. Fitzgerald, Michael S. Bloom, Francis P. Boscoe, David Orlo Carpenter, Richard F. Haase, Eugen S. Gurzau, Peter Rudnai, Kvetoslava Koppova, Joelle Fevotte, Giovanni Leonardi, Marie Vahter, Walter Goessler, Rajiv Kumar, Tony Fletcher

Epidemiology & Biostatistics Faculty Scholarship

Background: Studies suggest that ambient sunlight plays an important role in the pathogenesis of non-melanoma skin cancers (NMSC). However, there is ongoing controversy regarding the relevance of occupational exposure to natural and artificial ultraviolet radiation (UV) radiation.

Objectives: We investigated potential associations between natural and artificial UV radiation exposure at work with NMSC in a case-control study conducted in Hungary, Romania, and Slovakia. Methods: Occupational exposures were classified by expert assessment for 527 controls and 618 NMSC cases (515 basal cell carcinoma, BCC). Covariate information was collected via interview and multiple logistic regression models were used to assess associations between …

Efek Penyakit Kronis Terhadap Gangguan Mental Emosional, Giri Widakdo, Besral Besral

Kesmas

Hasil Riset Kesehatan Dasar tahun 2007 menunjukkan 11,6% penduduk Indonesia berumur 15 tahun ke atas mengalami gangguan mental emosional. Penelitian ini bertujuan untuk mengetahui efek penyakit kronis terhadap gangguan mental emosional. Desain penelitian ini adalah potong lintang menggunakan data Riskesdas tahun 2007. Sebanyak 660.452 responden berusia di atas 15 tahun yang tidak mengalami gangguan jiwa dijadikan sampel. Gangguan mental emosional dinyatakan ada jika responden mem-punyai paling tidak enam dari 20 gangguan. Penyakit kronis seperti tuberculosis (TB) paru, hepatitis, jantung, diabetes, kanker, dan stroke diukur melalui wawancara yang didasarkan pada diagnosis petugas kesehatan. Hasil penelitian menunjukkan bahwa dari sepuluh penderita penyakit …

Determinan Penyakit Stroke, Woro Riyadina, Ekowati Rahajeng

Kesmas

Penyakit stroke merupakan penyebab kematian dan kecacatan kronik yang paling tinggi pada kelompok umur di atas usia 45 tahun terbanyak di Indonesia. Tujuan penelitian ini untuk mengidentifikasi determinan utama yang berhubungan dengan penyakit stroke pada masyarakat di kelurahan Kebon Kalapa Bogor. Analisis lanjut terhadap 1.912 responden subset baseline data penelitian “Studi Kohort Faktor Risiko Penyakit Tidak Menular” Data dikumpulkan dengan metode wawancara pada penduduk tetap di kelurahan Kebon Kalapa, Kecamatan Bogor Tengah, Bogor tahun 2012. Diagnosis stroke berdasarkan anamnesis dan pemeriksaan dokter spesialis syaraf. Variabel independen meliputi karakteristik sosiodemografi, status kesehatan dan perilaku berisiko. Data dianalisis dengan uji regresi logistik …

Epidemiology News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• A Merged Model for Quality Improvement

Progress Realized: Trends In Hiv-1 Viral Load And Cd4 Cell Count In A Tertiary-Care Center From 1999 Through 2011, Howard B. Gale, Manuel D. Rodriguez, Heather J. Hoffman, Debra A. Benator, Fred M. Gordin, Ann M. Labriola, Virginia L. Kan

Epidemiology Faculty Publications

Abstract

Accumulating evidence suggests that alterations in immune function may be important in the etiology of papillary thyroid cancer (PTC). To identify genetic markers in immune-related pathways, we evaluated 3,985 tag single nucleotide polymorphisms (SNPs) in 230 candidate gene regions (adhesion-extravasation-migration, arachidonic acid metabolism/eicosanoid signaling, complement and coagulation cascade, cytokine signaling, innate pathogen detection and antimicrobials, leukocyte signaling, TNF/NF-kB pathway or other) in a case-control study of 344 PTC cases and 452 controls. We used logistic regression models to estimate odds ratios (OR) and calculate one degree of freedom P values of linear trend (PSNP-trend) for the association …

Impact Of The Tohoku Earthquake And Tsunami On Pneumonia Hospitalisations And Mortality Among Adults In Northern Miyagi, Japan: A Multicentre Observational Study, Hisayoshi Daito, Motoi Suzuki, Jun Shiihara, Paul E. Kilgore, Hitoshi Ohtomo, Konosuke Morimoto, Masayuki Ishida, Taro Kamigaki, Hitoshi Oshitani, Masahiro Hashizume, Wataru Endo, Koichi Hagiwara, Koya Ariyoshi, Shoji Okinaga

Department of Pharmacy Practice

Background On 11 March 2011, the Tohoku earthquake and tsunami struck off the coast of northeastern Japan. Within 3 weeks, an increased number of pneumonia admissions and deaths occurred in local hospitals.

Methods A multicentre survey was conducted at three hospitals in Kesennuma City (population 74000), northern Miyagi Prefecture. All adults aged ≥18 years hospitalised between March 2010 and June 2011 with community-acquired pneumonia were identified using hospital databases and medical records. Segmented regression analyses were used to quantify changes in the incidence of pneumonia.

Results A total of 550 pneumonia hospitalisations were identified, including 325 during the pre-disaster period …

Epidemiology News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Barriers to Cervical Cancer Screening

Faktor Risiko Diare Shigellosis Pada Anak Balita, A. Zulkifli Abdullah, A. Arsunan Arsin, Lidyawati Dahlan

Kesmas

Diare shigellosis pada balita merupakan masalah serius sebab dapat menyebabkan kematian. Untuk mengetahui faktor-faktor risiko kejadian shigellosis pada anak balita dilakukan studi kasus kontrol di beberapa rumah sakit di Kota Makassar dengan 68 kasus dan 136 kontrol. Data mengenai jenis kelamin dan status gizi anak balita, pemberian air susu ibu (ASI) eksklusif, status ekonomi, pendidikan ibu, kebiasaan ibu mencuci tangan memakai sabun, kepadatan hunian rumah, sarana air bersih, danjamban keluarga dikumpulkan dengan wawancara dan observasi serta dikategorikan dan disaring (screening) dengan uji chi square. Enam variabel dengan nilai p < 0,25 dimasukkan dalam uji regresi logistik yang menghasilkan variabel dengan nilai p < 0,05 (gizi rendah, ASI tidak eksklusif, dan status ekonomi rendah). Uji regresi logistik tahap kedua dengan 3 variabel ini menghasilkan model shigellosis = 1,47 gizi rendah + 1,471 ASI tidak eksklusif + 1,022 status ekonomi rendah - 2,546 dengan nilai oddsratio (OR) = 4,352 (gizi rendah), 4,353 (ASI tidak eksklusif), dan 2,779 (status ekonomi rendah). Studi ini menyimpulkan bahwa gizi balita yang rendah, pemberian ASI yang tidak eksklusif, dan status ekonomi ibu yang rendah merupakan faktor-faktor risiko penting kejadian diare shigellosis pada balita.

Shigellosis diarrhea is a serious issue to children under five years …

Ukuran Lingkar Pinggang Optimal Untuk Identifikasi Sindrom Metabolik Pada Populasi Perkotaan Di Indonesia, Krisnawaty Bantas, Hari Koesnanto Yoseph, Budi Moelyono

Kesmas

Sindrom metabolik (SM) adalah suatu kombinasi gangguan medis yang meningkatkan risiko diabetes tipe 2 dan penyakit kardiovaskuler. Salah satu kriteria sindrom metabolik adalah obesitas sentralis. Beberapa sumber mendefinisikan sindrom metabolik menggunakan ukuran lingkar pinggang yang berbeda yang belum tentu sesuai apabila diterapkan untuk populasi Indonesia. Penelitian ini bertujuan untuk mendapat nilai titik potong lingkar pinggang yang optimal sebagai salah satu kriteria SM yang sesuai dengan antropometri populasi Indonesia. Penelitian ini bersifat deskriptif menggunakan data sekunder yang berasal Riset Kesehatan Dasar (Riskesdas) Indonesia 2007. Sampel terdiri dari 13.262 orang berusia diatas 15 tahun pria dan wanita tidak hamil. Sebagai variabel dependen …

Can Changes In Angiogenic Biomarkers Between The First And Second Trimesters Of Pregnancy Predict Development Of Pre-Eclampsia In A Low-Risk Nulliparous Patient Population?, Leslie Myatt, Rebecca G. Clifton, J. M. Roberts, Catherine Y. Spong, Ronald J. Wapner, +10 Additional Authors

GW Biostatistics Center

OBJECTIVE:

To determine if change in maternal angiogenic biomarkers between the first and second trimesters predicts pre-eclampsia in low-risk nulliparous women.

DESIGN:

A nested case-control study of change in maternal plasma soluble Flt-1 (sFlt-1), soluble endoglin (sEng) and placenta growth factor (PlGF). We studied 158 pregnancies complicated by pre-eclampsia and 468 normotensive nonproteinuric controls.

SETTING:

A multicentre study in 16 academic medical centres in the USA.

POPULATION:

Low-risk nulliparous women.

METHODS:

Luminex assays for PlGF, sFlt-1 and sEng performed on maternal EDTA plasma collected at 9-12, 15-18 and 23-26 weeks of gestation. Rate of change of analyte between first and …

Modeling The Impact And Costs Of Semiannual Mass Drug Administration For Accelerated Elimination Of Lymphatic Filariasis, Wilma A. Stolk, Quirine A. Ten Bosch, Sake J. De Vlas, Peter U. Fischer, Gary J. Weil, Ann S. Goldman

Epidemiology Faculty Publications

The Global Program to Eliminate Lymphatic Filariasis (LF) has a target date of 2020. This program is progressing well in many countries. However, progress has been slow in some countries, and others have not yet started their mass drug administration (MDA) programs. Acceleration is needed. We studied how increasing MDA frequency from once to twice per year would affect program duration and costs by using computer simulation modeling and cost projections. We used the LYMFASIM simulation model to estimate how many annual or semiannual MDA rounds would be required to eliminate LF for Indian and West African scenarios with varied …

Environmental Exposure To Pyrethroids And Sperm Sex Chromosome Disomy: A Cross-Sectional Study, Heather A. Young, John D. Meeker, Sheena E. Martenies, Zaida I. Figueroa, Dana Boyd Barr, Melissa J. Perry

Epidemiology Faculty Publications

Background

The role of environmental pesticide exposures, such as pyrethroids, and their relationship to sperm abnormalities are not well understood. This study investigated whether environmental exposure to pyrethroids was associated with altered frequency of sperm sex chromosome disomy in adult men.

Methods

A sample of 75 subjects recruited through a Massachusetts infertility clinic provided urine and semen samples. Individual exposures were measured as urinary concentrations of three pyrethroid metabolites ((3-phenoxybenzoic acid (3PBA), cis- and trans- 3-(2,2-Dichlorovinyl)-1-methylcyclopropane-1,2-dicarboxylic acid (CDCCA and TDCCA)). Multiprobe fluorescence in situ hybridization for chromosomes X, Y, and 18 was used to determine XX, YY, XY, 1818, and …

Characterizing Inflammatory Breast Cancer Among Arab Americans In The California, Detroit And New Jersey Surveillance, Epidemiology And End Results (Seer) Registries (1988–2008), Kelly A. Hirko, Amr S. Soliman, Mousumi Banerjee, Julie Ruterbusch, Joe B. Harford, Robert M. Chamberlain, John J. Graff, Sofia D. Merajver, Kendra Schwartz

Wayne State University Associated BioMed Central Scholarship

Abstract

Introduction

Inflammatory breast cancer (IBC) is characterized by an apparent geographical distribution in incidence, being more common in North Africa than other parts of the world. Despite the rapid growth of immigrants to the United States from Arab nations, little is known about disease patterns among Arab Americans because a racial category is rarely considered for this group. The aim of this study was to advance our understanding of the burden of IBC in Arab ethnic populations by describing the proportion of IBC among different racial groups, including Arab Americans from the Detroit, New Jersey and California Surveillance, Epidemiology …

Molecular Epidemiology Of Early And Acute Hiv Type 1 Infections In The United States Navy And Marine Corps, 2005–2010, Richard A. Heipertz, Eric Sanders-Buell, Gustavo Kijak, Shana Howell, Michelle Lazzaro, Linda L. Jagodzinski, John Eggleston, Sheila Peel, Jennifer Malia, Adam Armstrong, Nelson L. Michael, Jerome H. Kim, Robert J. O'Connell, Paul T. Scott, David Brett-Major, Sodsai Tovanabutra

Journal Articles: Epidemiology

The U.S. military represents a unique population within the human immunodeficiency virus 1 (HIV-1) pandemic. The last comprehensive study of HIV-1 in members of the U.S. Navy and Marine Corps (Sea Services) was completed in 2000, before large-scale combat operations were taking place. Here, we present molecular characterization of HIV-1 from 40 Sea Services personnel who were identified during their seroconversion window and initially classified as HIV-1 negative during screening. Protease/reverse transcriptase (pro/rt) and envelope (env) sequences were obtained from each member of the cohort. Phylogenetic analyses were carried out on these regions to determine relatedness within the cohort and …

Combating Sti Epidemic: Community Perspectives Learned From Mixed-Gender Focus Group Study, K. M. M. Islam, Laura C. Vinson, Sherri Nared, Ira Combs, Melissa Tibbits, Shinobu Watanabe-Galloway, Ruth Margalit

Journal Articles: Epidemiology

Background. Since 2004, Douglas County in Nebraska has been experiencing higher rates of sexually transmitted infections (STIs) than the rest of the state. Northern Omaha has been considered to be one of the “hot spots” for STIs in the county. In 2011-2012, a focus group study was conducted to investigate the community’s perception of STIs and to identify strategies to increase the testing and treatment of STIs. Methods. Fourteen young adults were recruited to participate in two mixed-gender focus group sessions, each lasting 1.5 hours. Sessions covered various topics on STIs. Audio-recorded sessions were transcribed and analyzed by …

Comparing Two-Year Community College And Four-Year University Student Social And Behavioral Sexually Transmitted Infection Risk Factors, Oswald M. Attin

Faculty Dissertations

Sexually transmitted infections (STIs) could cause ectopic, cervical cancer, infertility, and organ damage to the heart, kidneys, and brain. This study compared several behavioral risk factors of STIs (condom use, number of sexual partners, type of sex (anal or vaginal) and drinking habits) between two distinct educational settings and their association with socioeconomic risk factors such as low income and parent’s lower level of education that are known to increase the incidence of STIs among college-aged students. This study was based on the precautionary-health-behavior model, where individuals act regardless of consequences, and the health-behavior-change model, where individual behaviors either increase …

Condom Negotiation Across Different Relationship Types By Young Women Engaged In Sex Work In Phnom Penh, Cambodia, Lisa Maher, Julie Mooney-Somers, Pisith Phlong, Marie-Claude Couture, Serey Serey Kien, Ellen Stein, Anna Juong Bates, Neth Sansothy, Kimberly Page, Young Women's Health Study Collaborative

Nursing and Health Professions Faculty Research and Publications

Cambodia’s 100% Condom Use Programme is credited with an increase in consistent condom use in commercial sexual interactions and a decrease in HIV prevalence among female sex workers (FSWs). There has been little improvement in condom use between FSWs and non-commercial partners, prompting calls for more innovative approaches to increasing condom use in these relationships. To understand why condoms are used or not used in sexual interactions involving FSWs, we examined condom negotiation across different types of relationships. We conducted 33 in-depth interviews with young (15 to 29 years) women engaged in sex work in Phnom Penh. There was an …

Information And Communication Technology To Link Criminal Justice Reentrants To Hiv Care In The Community, Ann Kurth, Irene Kuo, James Peterson, Nkiru Azikiwe, Lauri Bazerman, Alice Cates, Curt G. Beckwith

Epidemiology Faculty Publications

The United States has the world’s highest prison population, and an estimated one in seven HIV-positive persons in the USA passes through a correctional facility annually. Given this, it is critical to develop innovative and effective approaches to support HIV treatment and retention in care among HIV-positive individuals involved in the criminal justice (CJ) system. Information and communication technologies (ICTs), including mobile health (mHealth) interventions, may offer one component of a successful strategy for linkage/retention in care. We describe CARE+ Corrections, a randomized controlled trial (RCT) study now underway in Washington, that will evaluate the combined effect of computerized motivational …