Disparities Among Hispanic Ethnicity And Stage At Diagnosis For Invasive Breast And Colorectal Cancer,
2014
University at Albany, State University of New York
Disparities Among Hispanic Ethnicity And Stage At Diagnosis For Invasive Breast And Colorectal Cancer, Raquel Velazquez
Legacy Theses & Dissertations (2009 - 2024)
Objective: To assess the relationship between ethnicity and stage at diagnosis among invasive cases of breast and colorectal cancer.
An Evaluation Of Factors Leading To The Risk And Detection Of Thyroid Cancer,
2014
University at Albany, State University of New York
An Evaluation Of Factors Leading To The Risk And Detection Of Thyroid Cancer, Thomas James O'Grady
Legacy Theses & Dissertations (2009 - 2024)
Abstract:
Paternal Occupational Pesticide Exposure And Neural Tube Defects In The National Birth Defects Prevention Study,
2014
University at Albany, State University of New York
Paternal Occupational Pesticide Exposure And Neural Tube Defects In The National Birth Defects Prevention Study, Stacy Marie Pettigrew
Legacy Theses & Dissertations (2009 - 2024)
ABSTRACT
Sex Work And Daily Alcohol Use May Increase Hiv Risks Of Women Who Inject Drugs In Ukraine,
2014
University at Albany, State University of New York
Sex Work And Daily Alcohol Use May Increase Hiv Risks Of Women Who Inject Drugs In Ukraine, Tetyana Vasylyeva
Legacy Theses & Dissertations (2009 - 2024)
Background: Between 10 - 50% of female PWID in former USSR countries, where HIV epidemics are driven by injecting drug use, are reported to exchange sex for money, drugs or goods. Research in the region shows contradictory data on the association between exchange sex and HIV for PWID, and suggests that this association might be influenced by other factors. Since female PWID who exchange sex might be a bridge population between PWID and other people, it is important to monitor their risks and suggest timely interventions.
Sleep Duration And Diabetes In An Adult Population Of Rural Upstate New York,
2014
University at Albany, State University of New York
Sleep Duration And Diabetes In An Adult Population Of Rural Upstate New York, Tarak Shrestha
Legacy Theses & Dissertations (2009 - 2024)
Introduction: Within the past five decades, there has been a rapid increase in the number of diabetic cases in the US. The number of diabetic cases increased from 1.5 million in 1959 to 25.8 million in 2011. Around the same time period, the average sleep duration per night decreased from 8 hours to 6.9 hours.
Psychological Features Of Abstinent Heroin Users And Predictors Of Their Improvement During Rehabilitation In Saint-Petersburg, Russia,
2014
University at Albany, State University of New York
Psychological Features Of Abstinent Heroin Users And Predictors Of Their Improvement During Rehabilitation In Saint-Petersburg, Russia, Timofey Galankin
Legacy Theses & Dissertations (2009 - 2024)
Objective: Find predictors of adherence to post-detoxification rehabilitation programs in opiate intravenous drug users (IDUs) in Russia. Assess whether longer-term rehabilitation programs improve participants' psychological profiles more than shorter-term ones.
Medication Use And Patients Co-Infected With Human Immunodeficiency Virus And Hepatitis C Virus : Quantifying The Prevalence And Identifying The Predictors Of Clinically Significant Drug-Drug Interactions Associated With Therapy Containing First Generation Non-Structural 3a Serine Protease Inhibitors,
2014
University at Albany, State University of New York
Medication Use And Patients Co-Infected With Human Immunodeficiency Virus And Hepatitis C Virus : Quantifying The Prevalence And Identifying The Predictors Of Clinically Significant Drug-Drug Interactions Associated With Therapy Containing First Generation Non-Structural 3a Serine Protease Inhibitors, Nimish Patel
Legacy Theses & Dissertations (2009 - 2024)
This dissertation enhances our understanding of clinically significant drug-drug interactions (CSDDIs) and contraindicated drug interactions among patients with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection before and after the addition of HCV therapy including first generation non-structural (NS) 3A serine protease inhibitors. This is important to understand because the clinical sequelae of untreated chronic HCV infection are devastating yet drug-drug interactions greatly complicate treatment for these patients. The HIV/HCV coinfected population is a population that is particularly vulnerable because they are using a high volume of medications. Specifically, the standard of care for patients with HIV infection …
Atrazine In Maternal Drinking Water Supply Below The Federal Maximum Contaminant Level And Risk Of Preterm Birth, Small For Gestational Age, Cryptorchidism And Hypospadias,
2014
University at Albany, State University of New York
Atrazine In Maternal Drinking Water Supply Below The Federal Maximum Contaminant Level And Risk Of Preterm Birth, Small For Gestational Age, Cryptorchidism And Hypospadias, Daniel Rice
Legacy Theses & Dissertations (2009 - 2024)
The prevalence of preterm birth, small for gestational age (SGA), and hypospadias has been increasing for several decades in the U.S resulting in significant morbidity and mortality and direct costs to society. Drinking water provides a mechanism for prolonged chronic exposure to environmental contaminants but is one of the least assessed environmental exposures in pregnancy and birth outcomes. To test the hypothesis that maternal exposure to atrazine through drinking water during pregnancy, or one or more trimesters of gestation, is associated with an increased risk of preterm birth, small for gestational age, cryptorchidism and hypospadias a retrospective cohort study was …
Novel Partner Notification Approaches In New York State, And Antibiotic Resistance In The Management Of Chlamydia Trachomatis Infections,
2014
University at Albany, State University of New York
Novel Partner Notification Approaches In New York State, And Antibiotic Resistance In The Management Of Chlamydia Trachomatis Infections, Christopher Frank Davis
Legacy Theses & Dissertations (2009 - 2024)
Chlamydia trachomatis (chlamydia) is the most frequently reported notifiable disease in the United States. This dissertation provides an evaluation of chlamydia treatment and control through three different lenses: 1) patient views on a novel strategy to facilitate treatment, 2) student perceptions about materials to promote treatment of sexual partners, and 3) evidence regarding recurrent infection etiology.
Maternal Characteristics And Factors Associated With Hepatitis C (Hcv) Infection Among Hiv-Positive Pregnant Women In Ukraine, 2010-2011,
2014
University at Albany, State University of New York
Maternal Characteristics And Factors Associated With Hepatitis C (Hcv) Infection Among Hiv-Positive Pregnant Women In Ukraine, 2010-2011, Liudmyla Slobodianyk
Legacy Theses & Dissertations (2009 - 2024)
Objective: Determine the association between risk factors for Hepatitis C and hepatitis C (HCV) infection among HIV-positive pregnant women in Ukraine.
Social Support And Risky Sexual Behavior Among Male Migrant Market Workers From Central Asia In Almaty, Kazakhstan,
2014
University at Albany, State University of New York
Social Support And Risky Sexual Behavior Among Male Migrant Market Workers From Central Asia In Almaty, Kazakhstan, Gaukhar Mergenova
Legacy Theses & Dissertations (2009 - 2024)
Background: Many studies have shown that risky sexual behavior leads to increased rates of HIV infection among labor migrants. However, little is known about the role of social support in risky sexual behavior among labor migrants in Kazakhstan. This study explores the potential association between social support and risky sexual behaviors among male migrant market vendors in Almaty, Kazakhstan.
Perfluorinated Compounds, Thyroid Function, And Neuropsychological Status In Older Residents Of Upper Hudson River Communities,
2014
University at Albany, State University of New York
Perfluorinated Compounds, Thyroid Function, And Neuropsychological Status In Older Residents Of Upper Hudson River Communities, Srishti Shrestha
Legacy Theses & Dissertations (2009 - 2024)
Perfluorinated compounds (PFCs) are widespread in the environment. Minimal data exist regarding the neurotoxicity and thyroid disruptive property of PFCs in aging populations and the possible mediating effects of thyroid hormones (THs). In this study, we assessed associations among PFCs, thyroid function, and neuropsychological status, and determined if the neurotoxic effects of PFCs are mediated by changes in THs in an aging population. We measured perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), thyroid stimulating hormone (TSH), total thyroxine (T4), free T4 (fT4), and total triiodothyronine (T3) in serum and performed neuropsychological tests in men and women aged 55-74 years and living …
A Population-Based Case-Control Study Of The Association Between Extreme Heat Events And Neural Tube Defects And Oral Clefts,
2014
University at Albany, State University of New York
A Population-Based Case-Control Study Of The Association Between Extreme Heat Events And Neural Tube Defects And Oral Clefts, Aida Soim
Legacy Theses & Dissertations (2009 - 2024)
With climate change it is expected that extreme weather events will become more frequent and longer in duration. The health consequences of maternal exposure during pregnancy to extreme heat events are not well understood in spite of biological plausibility for adverse effects suggested by prior findings. There is very limited research that explores the relationship between extreme heat events and birth defects. The overall goal of this line of research was to determine whether heatwaves (HW) are associated with two major classes of birth defects: neural tube defects (NTDs) and oral clefts. One component of this project aimed to describe …
Initiation And Completion Of Adjuvant Chemotherapy Among Colorectal Cancer Patients,
2014
University at Albany, State University of New York
Initiation And Completion Of Adjuvant Chemotherapy Among Colorectal Cancer Patients, Ashar Ata
Legacy Theses & Dissertations (2009 - 2024)
Introduction: For regionally advanced colorectal cancers resection followed by adjuvant chemotherapy (ACT) is the recommended treatment. Despite consensus on benefits, studies have shown that a significant proportion of patients do not initiate it. Among those who initiate the survival benefits of chemotherapy cannot be fully realized without completed treatment. Without supplementing treatment information from insurance claims cancer registries are inadequate for assessment of ACT utilization. This study was aimed at measuring the initiation and completion of ACT among colorectal cancer patients and identifying the associated factors.
Dabigatran And Warfarin For Stroke Prevention In Atrial Fibrillation: Use, Switching, And Clinical Effects Following New Market Entry In Real-World Patients,
2014
Illinois Mathematics and Science Academy
Dabigatran And Warfarin For Stroke Prevention In Atrial Fibrillation: Use, Switching, And Clinical Effects Following New Market Entry In Real-World Patients, Julie C. Lauffenburger '03
Doctoral Dissertations
Patients with atrial fibrillation frequently benefit from anticoagulation to prevent stroke and systemic embolism. For decades, warfarin was the primary oral anticoagulant option despite its narrow therapeutic index requiring monitoring and drug-drug interactions. Dabigatran’s recent availability provides practical advantages including no monitoring and fewer interactions; however, it lacks a convenient reversal agent for bleeding events. Currently, it is unclear what factors have driven anticoagulant utilization since dabigatran’s introduction, and little real-world evidence on the agents’ comparative effectiveness and safety is available. The objectives were to describe dabigatran and warfarin’s utilization and switching patterns and assess their comparative effectiveness and safety. …
Exploration Of The Genetic Epidemiology Of Asthma: A Review, With A Focus On Prevalence In Children And Adolescents In The Caribbean,
2014
Old Dominion University
Exploration Of The Genetic Epidemiology Of Asthma: A Review, With A Focus On Prevalence In Children And Adolescents In The Caribbean, A. Mohan, A. J. Roberto, B. C. Whitehill, A. Mohan, A. Kumar
Biological Sciences Faculty Publications
Asthma is a chronic disease caused by the inflammation of the main air passages of the lungs. This paper outlines a review of the published literature on asthma. While a few studies show a trend of rising asthma cases in the Caribbean region, even fewer have explored the genetic epidemiological factors of asthma. This is a literature review that seeks to sum the body of knowledge on the epidemiology of asthma. Specifically, the major objective of the literature review is to provide a unified information base on the current state of factors involved in the genetic epidemiology of asthma. The …
Primary And Secondary Prevention Of Hepatitis C Virus Among Rural Appalachian People Who Use Drugs,
2014
University of Kentucky
Primary And Secondary Prevention Of Hepatitis C Virus Among Rural Appalachian People Who Use Drugs, Dustin B. Stephens
Theses and Dissertations--Clinical and Translational Science
Hepatitis C virus (HCV) remains a major cause of morbidity and mortality worldwide, with 3% of the global population chronically infected. Clinical impacts in the United States are projected to increase for two decades, and mortality attributed to HCV now exceeds HIV. Injection drug use (IDU) is the most common route of transmission in the developed world. Advances in treatment offer hope of mitigating HCV impacts, but substantial barriers obstruct people who inject drugs (PWID) from receiving care, particularly in medically underserved regions including Central Appalachia. This study assessed IDU paraphernalia sharing longitudinally over 24 months in a sample of …
Clinical Features, Proximate Causes, And Consequences Of Active Convulsive Epilepsy In Africa,
2014
Kenya Medical Research Institute, Kilifi, Kenya
Clinical Features, Proximate Causes, And Consequences Of Active Convulsive Epilepsy In Africa, Symon M. Kariuki, William Matuja, Albert Akpalu, Angelina Kakooza-Mwesige, Martin Chabi, Ryan G. Wagner, Myles Connor, Eddie Chengo, Anthony K. Ngugi, Rachael Odhiambo, Christian Bottomley, Steven White, Josemir W. Sander, Brian G. R. Neville, Charles R. J. C. Newton
Internal Medicine, East Africa
Purpose: Epilepsy is common in sub-Saharan Africa (SSA), but the clinical features and consequences are poorly characterized. Most studies are hospital-based, and few studies have compared different ecological sites in SSA. We described active convulsive epilepsy (ACE) identified in cross-sectional community-based surveys in SSA, to understand the proximate causes, features, and consequences.
Methods: We performed a detailed clinical and neurophysiologic description of ACE cases identified from a community survey of 584,586 people using medical history, neurologic examination, and electroencephalography (EEG) data from five sites in Africa: South Africa; Tanzania; Uganda; Kenya; and Ghana. The cases were examined by clinicians to …
Proximate And Evolutionary Insights Into The Epigenetics Of Posttraumatic Stress Disorder,
2014
Wayne State University
Proximate And Evolutionary Insights Into The Epigenetics Of Posttraumatic Stress Disorder, Levent Sipahi
Wayne State University Dissertations
Posttraumatic stress disorder (PTSD) is an important medical and social condition. Although the vast majority of individuals are exposed to traumatic events within their lifetime, a minority subsequently develop diagnosable PTSD. What underlies differential risk and resiliency in the face of trauma is an ongoing research and clinical question with implications for prevention and treatment. Recent work has revealed a putative role of epigenetic variation and modification - most notably DNA methylation - in the etiology of PTSD. That DNA methylation is stable, yet modifiable in response to lived experiences, makes it a strong candidate to mechanistically explain the ontogeny …
The Associations Between Homa-Ir And Muscular Strengthening Activity In Euglycemic U.S. Adults,
2014
University of North Florida
The Associations Between Homa-Ir And Muscular Strengthening Activity In Euglycemic U.S. Adults, William Robert Boyer Ii
UNF Graduate Theses and Dissertations
Background: Muscular strengthening activity (MSA) has been shown to be inversely associated with insulin resistance (IR). The associations between quartiles of the homeostatic model assessment of insulin resistance (HOMA-IR) and self-reported MSA in a nationally representative sample of euglycemic U.S. adults were examined.
Methods: Sample included adult participants (≥20 years of age [n=2,543]) from the 1999-2004 National Health and Nutrition Examination Survey (NHANES). HOMA-IR was categorized into quartiles based on every 25th percentile. No MSA was the dependent variable.
Results: Following adjustment for covariates, those with HOMA-IR values in third (p
Conclusions: Having a higher HOMA-IR value is associated …
