Epidemiology Commons^™

Coronavirus Disease-19 And Cardiovascular Disease: A Risk Factor Or A Risk Marker?, Jing Liu, Salim S Virani, Mahboob Alam, Ali E Denktas, Ihab Hamzeh, Umair Khalid

Faculty, Staff and Students Publications

Severe acute respiratory syndrome coronavirus-2 causes the clinical syndrome of coronavirus disease of 2019 (COVID-19) which has become a global pandemic resulting in significant morbidity and mortality. While the virus primarily affects the respiratory system, it also causes a wide variety of complex cardiac manifestations such as acute myopericarditis, acute coronary syndrome, congested heart failure, cardiogenic shock and cardiac arrhythmias. There are numerous proposed mechanisms of cardiac injury, including direct cellular injury, pro-inflammatory cytokine storm, myocardial oxygen-demand mismatch, and systemic inflammation causing multi-organ failure. Additionally, medications commonly used to treat COVID-19 patients have various cardiovascular side effects. We aim to …

Depression And Quality Of Life Among Adults With Asthma Presence In Nevada, Elizabeth D. Kahane

UNLV Theses, Dissertations, Professional Papers, and Capstones

Asthma is a lung disease that causes coughing, chest tightness, wheezing, and breathlessness. It is often controlled by medication use and avoidance of environmental triggers. It is a leading chronic, non-communicable disease affecting over 19 million adults in the United States (CDC, 2020a). Asthma and severe asthma have been shown to negatively affect mental health and quality of life among adults including limiting physical activity, lowering sleep quality, exacerbating economic challenges, missing work, and increasing healthcare use (Stanescu, et al., 2019). Approximately 8% of adult Nevadans reported current asthma symptoms and 12.6% reported having a diagnosis during their lifetime (CDC, …

Food Insecurity And Adiposity Among Children And Adults Nhanes 2015-2016, Denise Vidal

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Obesity is a preventable disease that has been associated with many adverse health outcomes. A possible factor that may influence adiposity development is food insecurity. Although several epidemiological studies have been conducted examining the association between food insecurity and adiposity among children and adults, results have been inconsistent. Objective: This cross-sectional study investigates the relationship between food insecurity and adiposity among children and adults using recent data from a representative sample of the US population. Methods: We examined 3,391 adults and 2,837 children from the National Health and Nutrition Examination Survey (NHANES) 2015-2016. Household food insecurity was assessed using …

Does Social Support Moderate The Association Between Income And Food Security Status Among Seniors Living In Southern Nevada?, Adugna Teka Siweya

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Income is the strongest predictor of food insecurity among seniors, and social support also an essential factor to help mitigate the effects of food insecurity. However, little is known about the potential role that social support may play as a moderator of the association between income and food insecurity. Thus, we aim to examine social support as a moderator for the relationship between income and food insecurity among seniors. Methods: Logistic regression models were used to analyze data collected in 2019 from seniors residing in Southern Nevada. Predictors of food insecurity, sociodemographic factors, social support variables, and income and …

Adherence To Mediterranean Diet Among Adolescents Attending Public Schools In North Lebanon, Rosy Mitri, Fouad Ziade

BAU Journal - Health and Wellbeing

The Mediterranean diet (MD) is a model of a healthy diet and healthy lifestyle. Adherence to the MD has been correlated with a reduction in many metabolic disorders including cancers. The factors associated with adolescents’ adherence to the MD in North Lebanon using the KIDMED index have never been explored. The objective of this study was to examine the factors associated with the Mediterranean diet (MD) adherence among a sample of Lebanese adolescents. A cross-sectional survey was conducted in the city of Tripoli, North Lebanon. A total of 298 students, aged 11-18 years, were randomly selected from public schools in …

Epigenome-Wide Association Study Of Kidney Function Identifies Trans-Ethnic And Ethnic-Specific Loci, Charles E. Breeze, Anna Batorsky, Mi Kyeong Lee, Mindy D. Szeto, Xiaoguang Xu, Daniel L. Mccartney, Rong Jiang, Amit Patki, Holly J. Kramer, James M. Eales, Laura Raffield, Leslie Lange, Ethan Lange, Peter Durda, Yongmei Liu, Russ P. Tracy, David Van Den Berg, Nhlbi Trans-Omics For Precision Medicine (Topmed) Consortium, Topmed Mesa Multi-Omics Working Group, Kathryn L. Evans, William E. Kraus, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this are poorly understood. We aimed to identify trans-ethnic and ethnic-specific differentially methylated positions (DMPs) associated with eGFR using an agnostic, genome-wide approach.

METHODS: The study included up to 5428 participants from multi-ethnic studies for discovery and 8109 participants for replication. We tested the associations between whole blood DNAm and eGFR using beta values from Illumina 450K or EPIC arrays. Ethnicity-stratified analyses were performed using linear …

Prevalence And Impacts Of Musculoskeletal Pain Among The Elderly Living In The East Coast Region Of Peninsular Malaysia, Muhammad Kamil Che Hasan, Nur Nabila Izzati Asmera, Suliza Sulaiman, Mohd Said Nurumal, Nik Noor Kaussar Nik Mohd Hatta

Makara Journal of Health Research

Background: Musculoskeletal pain commonly affects the elderly, but the extent of this problem within the Malaysian community remains unknown. This study aimed to investigate the prevalence and impact of musculoskeletal pain among the elderly living in the community.

Methods: Elderly individuals aged 60 years and above with musculoskeletal pain and intact cognition were recruited for this study. Musculoskeletal pain was scored using the Nordic Musculoskeletal Questionnaire, and functional ability was assessed via the Lawton Instrumental Activities of Daily Living scale. Mental wellbeing was evaluated using the Short Warwick–Edinburgh Mental Wellbeing scale, and risk of falling was determined via …

Prevalence And Associated Factors Of Urinary Incontinence Among Elderly In Pekanbaru, Indonesia, Wulan Sari

Makara Journal of Health Research

Background: The proportion of the elderly in Riau Province was 4.8% higher than that (4.2%) in 2011. Urinary incontinence (UI) is a common health problem among the elderly. This study aims to determine the prevalence and associated factors for UI among the elderly (≥60 years).

Methods: This cross-sectional study was conducted in 20 public health centers in Pekanbaru City in 2018. A total of 351 elderly meeting the inclusion criteria were enrolled. Gender, age, education, occupation, marital status, obesity, depression, cognitive impairment, smoking status, history of chronic cough, and history of lower abdominal surgery served as the independent …

Effects Of Ectodermal Dysplasia On The Maxilla: A Study Of Cone-Beam Computed Tomography, Beyza Karadede Ünal

Makara Journal of Health Research

Background: This study aimed to examine the effects of ectodermal dysplasia (ED) on the transverse width of the maxillary bone.

Methods: The ED group was composed of seven people, while the control group consisted of retrospective cone-beam computed tomography images of seven individuals with skeletal class 1 relationship. Images on the sagittal planes were taken, and cross-sections were taken from the longest point of the Anterior Nasal Spine-Posterior Nasal Spine line. The distance between the distal anterior canine teeth from the right buccal cortical bone to the left buccal cortical bone was measured. At the posterior region, the …

A Cross-Sectional Study On Bullying And Psychological Disturbances Among Malaysian School Children, Muhammad Lokman Md Isa, Nurfatin Aina Mocktar, Wisam Nabeel Ibrahim, Mohd Said Nurumal, Muhammad Kamil Che Hasan

Makara Journal of Health Research

Background: Bullying is a common violence in school and has become a major public health and global concern. Bullying influences mental health and is identified as a leading factor of depression. Therefore, this study aimed to identify bullying prevalence and its association toward psychological disturbances (stress, anxiety, and depression).

Methods: This cross-sectional study was conducted in three secondary schools in Kuantan. After obtaining consent from parents/guardians, participants were asked to answer a self-administered questionnaire, including School Climate Bullying Survey, Depression Anxiety Stress Questionnaire-21, Patient Depression Questionnaire, and Generalized Anxiety Disorder. Demographic data were self-reported. Data were analyzed using …

Controlling Dentistry-Related Musculoskeletal Disorders With Ergonomic Interventions In Lahore, Pakistan, Marriyam Nasar, Farwa Rubab, Hazik Bin Shahzad, Minam Qureshi, Maham Shahid, Pakiza Batool

Makara Journal of Health Research

Background: Musculoskeletal disorders (MSDs) usually result from a prolonged static position and repetitive movements. A comfortable environment, appropriate working position, and multiple short breaks could alleviate MSDs. While the occasional back or neck ache is not a cause for alarm, regularly occurring pain or discomfort, if ignored, may further develop into an injury or career-ending disability.

Methods: A total of 370 dentists were selected from two dental hospitals and multiple dental clinics in Lahore, Pakistan. Current MSDs were recorded with the Standardized Nordic Questionnaire (SNQ). Information sheets containing dental ergonomics and back and tendon-gliding exercises were distributed among …

Bridging The Inequality Gap Among Marginalized Populations In Africa Amid The Covid-19 Pandemic: A Call For Responsible Cooperation, Aanuoluwapo A. Afolabi, Olayinka S. Ilesanmi Dr., Titilope A. Afolabi

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Determinants Of Postnatal Care Service Utilization In Indonesia: A Secondary Analysis Using The Indonesian Health And Demographics Survey, Haerawati Idris, Willyana Syafriyanti

Makara Journal of Health Research

Background: The postnatal complication that occurs in the first week after childbirth is one of the causes of maternal death in Indonesia. However, it can be prevented with postnatal care (PNC). This study aims to analyze the determinants of PNC service utilization in Indonesia.

Methods: This quantitative study employed a cross-sectional study design and used secondary data from the Indonesian Health and Demographics Survey of 2017. The sample consisted of 14,724 women aged 15–49 years. We assessed the predictors of PNC service utilization using multivariate logistic regression models.

Results: About 78.4% of the respondents utilized PNC services. …

Soft Drink Consumption Patterns Of Middle School Students In North Okkalarpa, Moh Moh Thwe, Sein Yaw May, Min Htike Aung

Makara Journal of Health Research

Background: Urbanization and economic development in Myanmar have brought about culture and dietary transition from a traditional to a westernized diet. The health of the nation, especially the youth, may influence the changing dietary patterns: i.e., the higher the soft drink consumption, the higher the prevalence of soft drink-related diseases.

Methods: This cross-sectional study was carried out among 250 middle school students in North Okkalarpa Township, Yangon Region. Data were collected using self-structured questionnaires, and respondents were selected by using simple random sampling method.

Results: In this study, 81.2% of the students consumed soft drink once a …

Mothers’ Nutritional Knowledge, Self-Efficacy, And Practice Of Meal Preparation For School-Age Children In Yangon, Myanmar, Wut Yee Phyo, Ohn Khin Khin, Min Htike Aung

Makara Journal of Health Research

Background: Childhood malnutrition is a global public health concern. For Myanmar, mothers play a prominent role in improving the nutritional status of children as they prepare meals for children.

Methods: This community-based cross-sectional analytical study was conducted on 367 mother-child pairs (6–10 years). Significantly, systematic random sampling and structured questionnaires were utilized in this study.

Results: The mean age of mothers was 35.73 ± 6.9 years, and a majority had fair nutritional knowledge (52.3%), good self-efficacy (79.8%), and good practice of meal preparation (59.4%). The prevalence of childhood malnutrition was categorized as stunting (18.2%), underweight (18.8%), wasting …

Mortalidad Por Accidente Cerebrovascular En Guatemala 2018: Patrones E Inequidades, Alejandro Cerón, Gila Goldstein

Anthropology: Faculty Scholarship

El presente estudio busca analizar la mortalidad por accidente cerebrovascular (ACV) en Guatemala con el propósito de identificar posibles criterios epidemiológicos que orienten la priorización de acciones de salud pública. El riesgo de morir de ACV en Guatemala muestra marcadas desigualdades por departamento, las que son aún más marcadas al comparar por municipio. El riesgo de morir es también más alto en personas mestizas o ladinas, en niveles educativos bajos, y en personas que se dedican a ocupaciones elementales. Deberían implementarse medidas de salud pública orientadas a los municipios y grupos en mayor riesgo de morir de ACV. Este estudio …

Maternal Methylmercury Exposure Through Rice Ingestion And Child Neurodevelopment In The First Three Years: A Prospective Cohort Study In Rural China, Sarah E. Rothenberg, Susan A. Korrick, Jihong Liu, Yanfen Nong, Chuan Hong, Eva P. Trinh, Xu Jiang, Fred J. Biasini, Fengxiu Ouyang

Faculty Publications

Background

Rice is an important dietary source for methylmercury; however, rice does not contain the same beneficial nutrients as fish. Our main objective was to assess associations of prenatal methylmercury exposure through rice ingestion with child neurodevelopment in rural China.

Methods

Eligible peripartum women were enrolled (n = 391), provided peripartum hair samples, and children’s neurodevelopment was assessed at 12 months (n = 264, 68%) and 36 months (n = 190, 48%) using the Bayley Scales of Infant Development, 2nd Edition, including the Mental Developmental Index (MDI) and the Psychomotor Developmental Index (PDI). Associations between prenatal methylmercury …

Suppression Of Human Coronavirus 229e Infection In Lung Fibroblast Cells Via Rna Interference, Hamidreza Montazeri Aliabadi, Jennifer Totonchy, Parvin Mahdipoor, Keykavous Parang, Hasan Uludağ

Pharmacy Faculty Articles and Research

Despite extensive efforts to repurpose approved drugs, discover new small molecules, and develop vaccines, COVID-19 pandemic is still claiming victims around the world. The current arsenal of antiviral compounds did not perform well in the past viral infections (e.g., SARS), which casts a shadow of doubt for use against the new SARS-CoV-2. Vaccines should offer the ultimate protection; however, there is limited information about the longevity of the generated immunity and the protection against possible mutations. This study uses Human Coronavirus 229E as a model coronavirus to test the hypothesis that effective delivery of virus-specific siRNAs to infected cells will …

Efficiency With Covid-19: Home Vs. Dillon’S Rule States, Jason Kolb

Political Science Theses and Capstones

How does a state measure success when dealing with a pandemic like Covid-19? Can Dillon’s Rule keep their citizens happy and protected during a pandemic better then Home Rule? When local governments wait for the state to create policies, is this the best option for the state? Data will show a trend that states with a higher preemption rate have kept the death rate lower when dealing with the Covid-19 pandemic

Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram

The University of Louisville Journal of Respiratory Infections

Streptococcus milleri group (SMG) also referred to as the Streptococcus anginosus group. These are Gram-positive, variable hemolysis, catalase negative, microaerophilic, non-motile facultative anaerobes which have been known to cause abscesses in humans. We report a case of empyema caused by Streptococcus anginosus in a patient with an unresolved pneumonia for over a month. In early October 2018, the patient presented to an emergency room with the complaints of shortness of air, productive cough, chills, subjective fever and weight loss for 4 weeks. A chest X-ray revealed a left lower lobe pneumonia. He was treated with 250 mg of azithromycin for …