Pharmacy and Pharmaceutical Sciences Commons^™

Are Patients Living With Hiv Infection At Risk For Not Receiving Statin Medications For Cardiovascular Disease Risk Reduction?, Nick Hastain, Pharmd Candidate, Roshni S. Patel, Pharmd, Bcps, Jason J. Schafer, Pharmd, Mph, Bcps, Aahivp

College of Pharmacy Posters

Objective

To determine the prevalence of appropriate statin prescribing for ASCVD risk reduction in PLWH

Assessment Of Pharmacist Competency During Cardiopulmonary Arrest Code Participation In A Community Hospital, Lissette Bauza, Yarelys Garcia, Ada Jalice

All Publications

No abstract provided.

Retrospective Review Of Patients Treated With Argatroban For Heparin Induced Thrombocytopenia, Jessica Justiz, Jessica Greenwood, Heidi Clarke, Radhan Gopalani

All Publications

No abstract provided.

Impact Of A Urinary Tract Infection Treatment Pathway On Antimicrobial Prescribing Within A Community Hospital, Alyssa Donadio, Heidi Clarke, Erika Dittmar

All Publications

No abstract provided.

Executive Summary: A Comprehensive Report On Marijuana: Focus On The Paso Del Norte Region, Gabriel Frietze, Nora Hernandez, José O. Rivera

Departmental Papers (Pharmacy)

No abstract provided.

A Comprehensive Report On Marijuana: Focus On The Paso Del Norte Region, Gabriel Frietze, Nora Hernandez, José O. Rivera

Departmental Papers (Pharmacy)

The present executive summary highlights topics discussed within a comprehensive and extensive report on marijuana. This condensed summary discusses the chemical compounds within marijuana, the various methods of consuming marijuana, the therapeutic effects and health consequences associated with marijuana use, and repercussions that have emerged as a result of the legalization of marijuana in many states within the United States. Additionally, the impact of marijuana in communities within the Paso del Norte Region are discussed.

Read more: Executive Summary

Physical Properties And Solubility Studies Of Nifedipine-Peg 1450/Hpmcas-Hf Solid Dispersions, Rahul V. Haware, Bhavani Prasad Vinjamuri, Monika Gavireddi, Vivek S. Dave, Deepak Gupta, Mahavir B. Chougule, William C. Stagner

Pharmacy Faculty/Staff Publications

Low-order high-energy nifedipine (NIF) solid dispersions (SDs) were generated by melt solvent amorphization with polyethylene glycol (PEG) 1450 and hypromellose acetate succinate (HPMCAS-HF) to increase NIF solubility while achieving acceptable physical stability. HPMCAS-HF was used as a crystallization inhibitor. Individual formulation components, their physical mixtures (PMs), and SDs were characterized by differential scanning calorimetry, powder X-ray diffraction, and Fourier transform infrared spectroscopy (FTIR). NIF solubility and percent crystallinity (PC) were determined at the initial time and after 5 days stored at 25 °C and 60% RH. FTIR indicated that hydrogen bonding was involved with the amorphization process. FTIR showed that …

Evaluation Of A Daptomycin Dosing Protocol Based On Adjusted Body Weight At A Community Hospital, Lorenzo Porras Jr.

All Publications

No abstract provided.

Retrospective Review Of Alternative Antibiotic Use In Patients With A Reported Penicillin Allergy At A Community Hospital, Rita Chamoun, Monica Tadros, Amy Montes, Heidi Clarke, Radhan Gopalani

All Publications

No abstract provided.

Retrospective Review Of Oral Oncolytic Agent Use Within A Community Hospital, Alyssa Donadio, Moe Shwin, Maria Figueroa, Michelle Lamarque

All Publications

No abstract provided.

Canvass: A Crowd-Sourced, Natural-Product Screening Library For Exploring Biological Space, Sara E. Kearney, Gergely ZahoráNszky-KőHalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Robert B. Grossman

Chemistry Faculty Publications

Natural products and their derivatives continue to be wellsprings of nascent therapeutic potential. However, many laboratories have limited resources for biological evaluation, leaving their previously isolated or synthesized compounds largely or completely untested. To address this issue, the Canvass library of natural products was assembled, in collaboration with academic and industry researchers, for quantitative high-throughput screening (qHTS) across a diverse set of cell-based and biochemical assays. Characterization of the library in terms of physicochemical properties, structural diversity, and similarity to compounds in publicly available libraries indicates that the Canvass library contains many structural elements in common with approved drugs. The …

Ongoing Evaluation Of The Impact Of A Post-Operative Atrial Fibrillation Prevention Protocol For Patients Undergoing Cardiothoracic Surgery, Kamarena Sankar, Jonatha Kline, Heidi Clarke, Radhan Gopalani, Faaria Quadri

All Publications

No abstract provided.

Burrus, Swan Brasfield, 1855-1936 (Sc 3304), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid and scan (Click on "Additional Files" below) for Manuscripts Small Collection 3304. Letter to a Mr. Parker from Swan Burrus, State Line, Kentucky, referring to his children’s interest in an estate. He reminds Parker of his delivery of a bond as guardian for the three youngest children, and asks for further instructions. The letter is written on letterhead from the Office of Burrus Brothers, Drugs and General Merchandise, and bears an illustrated advertisement for Dr. Brown’s Family Remedies promising relief from a variety of complaints.

Pharmacist Interventions Involving Patient Outreach: Early Findings Of Patient Outcomes In Older Adults, Matthew Fair Bs, Pharmd, Bcps, Bcgp,, Michelle Omari-Okyere Bs, Pharmd, Bcps, Bcgp, Elie Jabbour Pharmd, Mba,, Brenda Frutos Mph, Ches, Nyann Biery Ms

Department of Pharmacy

No abstract provided.

Evaluation Of Antibiotic Prescribing Patterns For Community Acquired Pneumonia, Gregory Schaefer, Ann Wigton

Pharmacy Posters

Purpose: To evaluate duration of antibiotic therapy and prescribing patterns for non-ICU CAP at St Cloud Hospital, a tertiary community hospital.

Evaluation Of The Transition To A Fixed-Dose Prothrombin Complex Concentrate Regimen At A Tertiary Regional Medical Center, John Mullen, Lance Mcnab

Pharmacy Posters

Objective:

• Evaluate order set use in patients that received PCC for emergent warfarin reversal in the emergency department both before and after implementation of a fixed-dose protocol.
• Evaluate INR response to administration of PCC pre- and post- implementation and the percentage of post-infusion INRs that were less than 2 and 1.5.
• Assess cost of therapy before and after implementation of the fixed-dose protocol.

Evaluation Of Neonatal Abstinence Syndrome Management And Prescribing Patterns, Kaylee Erickson, Anthony Wieland, Kaia Ringwald

Pharmacy Posters

Purpose:

• Identify medications prescribed to manage NAS due to opioids and /or amphetamines.
• Evaluate average daily medication wean rates.
• Assess length of stay (LOS) and length of treatment (LOT)

Calcitriol And Calcipotriol Modulate Transport Activity Of Abc Transporters And Exhibit Selective Cytotoxicity In Mrp1-Overexpressing Cells, Kee W. Tan, Angelina Sampson, Bremansu Osa-Andrews, Surtaj H. Iram

Chemistry and Biochemistry Faculty Publications

Efflux transporters P-glycoprotein (P-gp/ABCB1), multidrug resistance protein 1 (MRP1/ABCC1), and breast cancer resistance protein (BCRP/ABCG2) can affect the efficacy and toxicity of a wide variety of drugs and are implicated in multidrug resistance (MDR). Eight test compounds, recently identified from an intramolecular FRET-based high throughput screening, were characterized for their interaction with MRP1. We report that the active metabolite of vitamin D3, calcitriol, and its analog calcipotriol are selectively cytotoxic to MRP1-overexpressing cells, besides inhibiting transport function of P-gp, MRP1, and BCRP. Calcitriol and calcipotriol consistently displayed a potent inhibitory activity on MRP1-mediated doxorubicin and calcein efflux in MRP1-overexpressing H69AR …

Characterization Of Antibiotic Use For Acute Otitis Media In Pediatric Physician Practices, Jasica N. Truong Pharmd, Kristin M. Held Pharmd, Bcop, Jennifer E. Macfarlan Mph, Tibisay Villalobos Md, Faap

Department of Pharmacy

No abstract provided.

Assessment Of The Use Of Non-Pharmacological Methods For Managing Depression In Patients With Myotonic Dystrophy (Dm) And Facioscapulohumeral Muscular Dystrophy (Fshd), Mackenzie Roberts, Amy L. Parkhill, Deidre Skalla, Kimberly Miller

Pharmacy Faculty/Staff Publications

Background: Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are two types of muscular dystrophies with multi-system manifestations.

Purpose: The purpose of this study was to determine 1: the prevalence of depression in patients with myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) and 2: which non-pharmacological methods DM and FSHD patients are using to manage their depression.

Methods: A survey was conducted using the online system, Qualtrics. The voluntary and anonymous survey was emailed to 1,205 eligible patients from the National Registry for DM and FSHD Patients and Family Members at the University of Rochester. Participants were at least …