Pharmacy and Pharmaceutical Sciences Commons^™

Development And Pilot Implementation Of A Generative Ai-Powered Virtual Learning Assistant (Vla) In First-Year Pharm.D. Courses, Vivek S. Dave, Ankit Rochani, Priyanka Bhatt

Fisher Showcase 2026

To develop and implement a generative AI-powered Virtual Learning Assistant (VLA) within foundational Pharm.D. pharmaceutics courses (Pharmaceutics I & II).

Dispensing Discovery: A Summer Camp Approach To Pharmacy Recruitment., Mary Wines-Samuelson, Gabriela Cipriano, Ankit Rochani, Ramil Sapinoro, Juliette Miller, Kaylee Schelah, Jill C. Hardy, Christine R. Birnie Phd

Fisher Showcase 2026

No abstract provided.

Innovations In Pharmacy Resident Research To Streamline Preceptor Workload And Improve Publication Rates, Kathryn A. Connor, Nicole M. Acquisto, Jennifer Iuppa Melaragno, Samantha C. Heacock, Stephen Rappaport

Fisher Showcase 2026

Organization: Nine-hospital health system (includes 886-bed academic medical center, 261-bed academic community hospital, 12 outpatient pharmacies, specialty pharmacy program); pharmacy residency program spans 2 hospitals.

Residency Programs: Currently, 5 PGY1 Pharmacy (3 academic medical center, 2 community teaching hospital), 2 PGY1 community-based pharmacy and 7 PGY2 programs in ambulatory care, critical care, emergency medicine, infectious diseases, oncology, pediatrics, and specialty pharmacy administration and leadership.

Pharmacy Research Committee (PRC): Comprised of ~10 clinical pharmacists and local pharmacy school faculty members including 2 co-chairs, research administrative pharmacist, biostatistician, and clinical informatics pharmacist experienced in research methods who meet monthly and otherwise communicate …

Tutor Resource Utilization And Course Outcomes In The Systems Pharmacology Course Sequence, Michael A. Currier, Amy L. Parkhill, Kelly Conn

Fisher Showcase 2026

To describe student utilization of tutoring resources and the relationship with academic outcomes in four Systems Pharmacology courses.

Brain Delivery Of Antibody-Derived Biologicals For Alzheimer’S Disease: An Updated Narrative Review, Rachita K. Sumbria, Ruben J. Boado

Pharmacy Faculty Articles and Research

Antibodies directed against β-amyloid (Aβ) have been developed for the treatment of Alzheimer’s disease (AD). However, the in vivo central efficacy is reduced by the poor penetration of antibodies across the blood–brain barrier (BBB). In addition, these antibodies have been associated with adverse effects like amyloid-related imaging abnormalities. Thus, the development of new antibody-based therapies for AD with improved transport across the BBB may improve efficacy and reduce adverse effects. Antibodies targeting the BBB transferrin receptor (TfR) are able to cross the BBB through receptor-mediated transcytosis, producing a global distribution throughout the brain. Along the same line, bispecific antibodies directed …

Assessing Current Telehealth Mobile Applications In The United States: Accessibility, Privacy, And Care Delivery, Rosemary K. Frugé

Honors Theses

Telehealth has improved patient access by reducing barriers to convenient, cost-effective, and quality health care. Telehealth mobile applications allow individuals to remotely access services through smartphone-based platforms. The purpose of this study was to evaluate leading telehealth applications available in the United States, analyzing key factors that influence platform selection, including cost, prescribing and diagnostic capabilities, user feedback, and data privacy practices. Applications were identified through keyword-based searches of major app stores using the term “telehealth,” and each app was systematically evaluated using predefined criteria. Findings highlight variability across platforms in pricing transparency, service offerings, and privacy disclosures, despite generally …

Comparative Physicochemical Characterization Of Porcine, Fish, And Bovine Gelatin In Gummy Candies: Toward Halal Nutraceutical Development, Marlyn Dian Laksitorini, Cici Darsih, Nunung Yuniarti, Rumiyati Rumiyati, Mohammad Zainal Abidin

Pharmaceutical Sciences and Research

Gummy candies have emerged as one of the most popular dosage forms for multivitamins and nutraceutical supplements, including those for brain health. Gelatin is the primary gelling agent used to achieve the gummy texture; however, the influence of different gelatin sources on the physicochemical properties of gummies has not been systematically examined. This study investigated the physicochemical characteristics of gummies prepared with porcine, bovine, and fish gelatin. The gummies were evaluated for mechanical properties (gumminess, hardness, cohesiveness, springiness, adhesiveness, and stringiness), color, water activity, antioxidant activity, and protein content. Additionally, the effects of intentional adulteration—specifically the addition of porcine gelatin …

Ethical Decision-Making Frameworks In Ai-Driven Pharmaceutical Research & Development, Dhaval Dinesh Panchal, Osama Mohd Hash Ansari, Sudha Divya Madhuri Kallam

Harrisburg University Dissertations and Theses

Artificial intelligence is increasingly being utilized in pharmaceutical research and development to speed up drug discovery, enhance clinical trial design, and support regulatory decision-making. However, the increasingly rapid adoption of AI in the pharma industry has outpaced the development of consistent ethical governance, raising concerns related to data privacy, transparency, regulatory compliance, and stakeholder trust. This study explored the methods by which project managers could develop and utilize ethical decision-making frameworks to facilitate responsible AI implementation in pharmaceutical research and development. Guided by the Responsible Innovation framework, this research employed a mixed-methods design combining semi-structured interviews and quantitative surveys with …

Structural Transformation Of A Hydrogel-Forming Cell Division Protein Zapb Of Multidrug Resistant Klebsiella Pneumoniae With Small Molecules, Ayesha Khan, M. Iqbal Choudhary, Sumaira Javaid, Humaira Zafar, Innokentiy Maslennikov, Atia-Tul Wahab

Pharmacy Faculty Articles and Research

Septal ring assembly protein ZapB (EMR18431.1) is involved in Z-ring formation, and nucleoid segregation during the bacterial cell division . It promotes cell division in the initial stages of the cell cycle through direct interaction with FtsZ, thus stimulating Z-ring assembly. The ZapB inhibition can make bacterial cell susceptible to primary antibiotics, and therefore considered as an important approach for adjuvent therapy against MDR bacterial infections. Hence in the current study, ZapB protein of multidrug resistant Klebsiella pneumoniae was cloned, and expressed in E. coli system. To understand its role, and to assess the mechanism of ZapB activation, the characteristic …

Improving Anesthesia Provider Confidence In The Identification, Management, And Treatment Of Postoperative Delirium, Brittany M. Whistle, Charles Dustin Phelps

Scholars Week

Purpose: Postoperative Delirium (POD) is a potentially devastating complication of anesthesia that is poorly understood by clinical staff leading to poor outcomes for surgical patients. This study is meant to determine if a focused knowledge presentation accompanied by visual aids could increase anesthesia providers confidence in identifying, diagnosing, and treating Postoperative Delirium.

Methodology: Utilizing a statistical model to analyze respondents results on a standardized test administered before and after an informational presentation with visual aids on the topic of Postoperative Delirium.

Results: Results indicated a statistically significant difference between pretest and posttest scores, with a p-value of .002, t(11) = …

Pacific Rxtracts - April 2026, Pacific Rxtracts

Pacific RxTracts

Articles:

• LAMA‑LABA Inhalers in COPD
• Another Potential Indication for Dupilumab: Chronic Spontaneous Urticaria
• Clinical Pharmacist‑Led Tobacco Treatment and Contingency Management in Patients With HIV
• FDA Approves First TYK2 Inhibitor for Adults With Active Psoriatic Arthritis
• Oral PCSK9 Inhibition with Enlicitide: A New Frontier in Lipid‑Lowering Therapy
• Lerodalcibep‑liga, Novel PCSK9 Inhibitor for the Management of Hypercholesterolemia
• Pharmaceutical Grade Cannabidiol for Myocardial Recovery in Acute Myocarditis
• Berberine Shows Limited Impact on Visceral and Liver Fat in MASLD Trial
• Comparative Outcomes of Orforglipron and Oral Semaglutide in Adults with Type 2 Diabetes
• Battling Pediatric Episodic Migraines – FDA Expands Approval of Fremanezumab
• Navepegritide …

Exploring Synthesized Cbd Derivatives: Implications Of Therapeutic Strategies For Neuroinflammation, Josephine Mosser

Senior Theses

Cannabidiol (CBD) is a non-psychoactive phytocannabinoid derived from Cannabis Sativa with well-documented antioxidant and anti-inflammatory properties, yet its clinical utility is limited by moderate receptor selectivity, rapid hepatic metabolism, and broad pharmacological activity on the central nervous system (CNS). This thesis describes the design and partial execution of a multi-step synthetic route aimed at generating CBD/CBD-derived chalcone intermediates for potential therapeutic applications for neuroinflammation. The steps encompass an O-methylation, O-acetylation, and a Fries rearrangement. The first three steps were completed successfully and reproducibly shown through 1H-NMR and 12C-NMR; however, purification of the fourth step was not successful within the available …

April 2026, Swosu Rural Health Center

RURAL ROCKS

• Oklahoma Rural Health Transformation Program
• State Immunization Websites
• Tracking Measles Cases in the U.S.
• FDA to Address Unused Opioids in American Homes
• Immune cells may underlie sex differences in chronic pain
• STRESS AWARENESS MONTH

Folic Acid–Carbon Dot–Gemcitabine Nanoparticles For Targeted Cancer Drug Delivery, Irfan Huda, Hua Mei

SPARK Symposium Presentations

This project aims to develop a folic acid-attached carbon dot nanoparticle system (FA-CDs-GEM) for the targeted delivery of gemcitabine to cancer cells. While gemcitabine is widely used, its effectiveness is limited because a short in vivo half life and lack of selectivity, which lead to severe side effects. Carbon dots offer a simple and modifiable platform as the drug delivery and bioimaging agent. Conjugation of folic acid to the carbon dots enables selective targeting of cancer cells that overexpress folate receptors. In this study, we synthesized and characterized FA-CD-GEM nanoparticles and developed an HPLC calibration curve of GEM to accurately …

Patenting The Unexpected, Sean B. Seymore

Vanderbilt Law School Faculty Publications

Unexpected discoveries have transformed human existence. They’ve revolutionized science and spawned entire new fields of research. While unexpected discoveries seem inventive and worthy of patent protection, they don’t formally align with traditional patent theory. The bedrock principle that an invention begins with the conception of an idea in the inventor’s mind and ends with implementation doesn’t apply to unexpected discoveries. This misalignment is most acute for pharmaceuticals, where the discovery of new uses for old drugs has tremendous social and economic importance. Since a drug can inherently treat multiple conditions in a patient—even those unknown to the patient, doctor, or …

Sharksrx Newsletter Spring 2026, Nova Southeastern University

NSU Sharks Rx

No abstract provided.

3rd Place Contest Entry: "Examining Physicians’ Behaviors Regarding Buprenorphine Prescribing For Opioid Use Disorder", Khashayar Eshtiaghi

Eric M. Scandrett Graduate Library Research Prize

This is Khashayar Eshtiaghi's submission for the 2026 Eric M. Scandrett Graduate Research Prize, which won third place. It contains their essay on using library resources, a summary of their research project on physicians' behaviors regarding buprenorphine prescribing for opioid use disorde, and their bibliography.

Khashayar is a student in the Ph.D. in Pharmaceutical Economics and Policy program at Chapman University. Their faculty mentor is Dr. Marc Fleming.

2025 Novel Drug Approvals, Katherine Ghattas Pharmd, Amanda Rawa Pharmd

Transformative Medicine

The year 2025 marked another strong chapter in pharmaceutical innovation, with multiple novel therapies gaining approval from the U.S. Food and Drug Administration (FDA). These approvals reflect continued progress in addressing unmet medical needs across a wide range of disease states. This article reviews the FDA’s 2025 novel drug approvals, spotlighting a few therapeutic advancements and emerging trends. A comprehensive table of all approved agents is provided, along with a focused discussion of four particularly impactful therapies: donidalorsen (Dawnzera), taletrectinib (Ibtrozi), delgocitinib (Anzupgo), gepotidacin (Blujepa), etripamil (Cardamyst). Each of these agents represents a step forward in its respective field and …

Phytochemistry And Pharmacological Activities Of Sphagneticola Trilobata: A Systematic Review With Perspectives For Drug Discovery, Sonali Dnyaneshwar Labhade, Suraj Kamadi, Pawan Nandkishor Karwa, Ritesh Prakash Bhole, Harshad Sunil Kapare, Sohan Satyanarayan Chitlange

Makara Journal of Science

Sphagneticola trilobata (L.) Pruski is a medicinal plant widely used in traditional medicine for its anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, wound healing, and CNS depressant effects. Despite its broad pharmacolo-gical potential, clinical application is limited due to a lack of mechanistic understanding, standardization, and clinical validation. This review aims to provide a comprehensive overview of the phytochemical composition, pharmacological activities, and therapeutic potential of S. trilobata, while highlighting research gaps and suggesting future directions for clinical translation. A systematic review of scientific literature, ethnobotanical sources, and pharmacological studies was conducted, focusing on phytochemical analysis, biological activity, toxicity, and potential applications …

Comparative Antiscabies Efficacy Of Sonneratia Alba Extracts: Evaluation Of Plant Parts And Concentrations In Mice, Delima Engga Maretha, Lara Mukti Taresha, Karina Yuliana, Iis Ariska, Silvia Diah Lestari

Makara Journal of Science

This study evaluated the antiscabies efficacy of 70% ethanol extracts from various parts of the mangrove Sonneratia alba (leaves, flowers, bark, and roots) as a potential alternative therapy. The primary objective was to compare the healing effects of the extracts at different concentrations on scabies lesions in mice (Mus musculus). Using a completely randomized design, 24 male Swiss Webster mice were assigned to four groups: a control (K0) group and three treatment groups to receive 10% (K1), 20% (K2), and 30% (K3) extract concentrations topically twice daily. The results demonstrated that the S. alba extracts had significant effects …