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Ada News - 12/11/2017, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Analytical Methods Used To Detect Fluoride In Dental Pharmaceuticals, Amber Aboona

Honors College Theses

My thesis, “The Analytical Methods Used to Detect Fluoride in Dental Pharmaceuticals” discusses the various analytical chemistry methods which are incorporated in the field of dentistry in order to detect fluoride in pharmaceuticals such as toothpaste and mouthwash. The oral cavity is exposed to various forms of bacteria, many of which enter through the consumption of foods and drinks that contain sugar and starch. The side effects of fluoride have been a controversial component of oral healthcare, however, many benefits have been discussed. Water fluoridation has been one of many significant methods of incorporating fluoride into the oral cavity, enhancing …

The Assessment Of A School-Based Dental Program, Peggy H. Hyden

Dental Hygiene ETDs

The Assessment of a School-Based Dental Program

by

Peggy H. Hyden

B.S., Dental Hygiene, Caruth School of Dental Hygiene, Texas A&M College of Dentistry, 1979 M.S., Dental Hygiene, University of New Mexico, 2018

ABSTRACT Purpose: The purpose of this study was to compare non-participants and participants of a school-based dental program and assess the utilization and satisfaction of services offered. Methods: Sixty-seven hundred questionnaires, containing 20 questions, were distributed to the parents/guardians of the Carlsbad and Loving school systems. Surveys were taken home by the students, given to the parent/guardians and returned within 1 week. Descriptive statistics was used to …

Relationship Between Self-Reported Oral Health And Self-Esteem In Two Columbia, Sc Populations, Matthew Ablonczy, Elizabeth Smith

Senior Theses

The importance of oral health to overall health cannot be overstated. For example, oral health can be used for early diagnosis of diseases such as diabetes. Furthermore, it has been well studied that self-esteem is related to oral health. Individuals with proper oral health care have more confidence to interact with others, which results in higher self-esteem. Those who lack the ability to pay for oral healthcare are thus at a great disadvantage. The present study sought to investigate the relationship between oral health and self-esteem in two Columbia, SC populations through surveying. There were two study populations, students at …

Clinical Cases In Endodontics; Chapter 1: Introduction, Takashi Komabayashi

Dental Medicine Faculty Publications

Chapter 1 of Clinical Cases in Endodontics, a problem-based text that presents a wide range of real cases in endodontics. Clinical Cases in Endodontics presents actual clinical cases, accompanied by academic commentary, that question and educate the reader about essential topics in endodontic therapy. It begins with sets of cases illustrating the most common diagnoses and the steps involved in preparing a treatment plan. Subsequent chapters continue in this style, presenting exemplary cases as the basis of discussing various treatment options, including nonsurgical root canal treatment, re-treatment, periapical surgery, internal and external resorption, emergencies and trauma, and treating incompletely developed …

Comparison Of Apical Centring Ability Between Incisal-Shifted Access And Traditional Lingual Access For Maxillary Anterior Teeth, Yoshio Yahata, Yoshiko Masuda, Takashi Komabayashi

Dental Medicine Faculty Publications

The aim of this study was to compare the apical centring ability of incisal-shifted access (ISA) with that of traditional lingual access (TLA). Fifteen three-dimensional printed resin models were prepared from the computed tomography data for a human maxillary central incisor and divided into ISA (n=7), TLA (n=7), and control (n=1) groups. After access preparation, these models were shaped to the working length using K-files up to #40, followed by step-back procedures. An apical portion of the model was removed at 0.5 mm coronal to the working length. Microscopic images of each cutting surface were taken to measure the preparation …

Heredity, Genetics And Orthodontics: How Much Has This Research Really Helped?, James K. Hartsfield Jr., George Jeryn Jacob, Lorri Ann Morford

Oral Health Science Faculty Publications

Uncovering the genetic factors that correlate with a clinical deviation of previously unknown etiology helps to diminish the unknown variation influencing the phenotype. Clinical studies, particularly those that consider the effects of an appliance or treatment regimen on growth, need to be a part of these types of genetic investigations in the future. While the day-to-day utilization of "testing" for genetic factors is not ready for practice yet, genetic testing for monogenic traits such as Primary Failure of Eruption (PFE) and Class III malocclusion is showing more promise as knowledge and technology advances. Although the heterogeneous complexity of such things …

Is Antimicrobial Photodynamic Therapy A Useful Therapeutic Protocol For Oral Decontamination? A Systematic Review And Meta-Analysis, Sergio Varelakellesarian, Faisal Qayyum, Paula C.De Freitas, Zohaib Akram, Fawad Javed

Section of Dental-Oral Maxillofacial Surgery

Background: The aim of the present systematic review and meta-analysis was to assess the efficacy of antimicrobial photodynamic therapy (aPDT) as a therapeutic protocol for oral decontamination.
Methods: In order to address the focused question: Is aPDT a useful therapeutic protocol for oral decontamination?, an electronic search without time or language restrictions was conducted up to July 2017 in indexed databases using the combination of different key words including photochemotherapy, lasers, photodynamic therapy, disinfection, mouth, saliva and oral. The exclusion criteria included reviews, case-reports, case-series, commentaries, letters to the editor, interviews, and updates. Four randomized control trials were included and …

Comparison Of Antibacterial Activity Of Ozonated Olive Oil And Chlorhexidine Gluconate, Changmin Lee

Loma Linda University Electronic Theses, Dissertations & Projects

Aim: The aim of this in vitro disk diffusion susceptibility test is to compare the antibacterial activity of ozonated olive oil (OzOO) with chlorhexidine gluconate (CHX) against periodontal pathogens, Porphyromonas gingivalis and Aggregatibacter Actinomycetemcomitans. Materials and Methods: The antibacterial activity of two antiseptics, OzOO and CHX, and, two controls, olive oil and normal saline was assessed by disk diffusion susceptibility test. For disk diffusion susceptibility test, two periodontal pathogens, 20 petri dishes for P. gingivalis and 18 petri dishes for A. actinomycetemcomitans, were used. To assess the antibacterial activity, the diameters of the growth inhibition zone were measured with a …

The Role Of Kinases And Phosphatases In The Pathobiology Of Porphyromonas Gingivalis., Sarah Whitmore

Electronic Theses and Dissertations

Periodontal diseases result from the interplay between the dysregulation of the host inflammatory response and the actions of a dysbiotic bacterial community. These chronic inflammatory conditions affect persons on a worldwide scale. P. gingivalis is strongly implicated as a key periodontal pathogen in the more severe manifestations of periodontal diseases such as periodontitis. A core element of P. gingivalis pathogenicity is its dysregulation of innate immunity, including suppression of IL-8 production by gingival epithelial cells. The NF-κB family of related transcription factors plays a central role in regulating many important aspects of innate immune responses. NF-κB RelA/p65 homodimers regulate transcription …

Deficiency Of Rdh10 Causes Cleft Secondary Palate In Mouse., Swetha Raja

Electronic Theses and Dissertations

The focus of this project is to understand the role of Retinoic Acid (RA) produced by RDH10-mediated metabolism of Vitamin A in palate development. For 80 years now, we have known that dietary restriction of RA/Vitamin A can cause cleft palate but we have failed to understand how RA deficiency causes cleft palate. Our gap in knowledge about how RA deficiency causes cleft palate is mainly owing to the fact that we lack a model system to study such defects. The aim of this thesis research project was to determine if conditional inactivation of the Vitamin A metabolic gene Rdh10 …

Type Ix Secretion System: Characterization Of An Effector Protein And An Insight Into The Role Of C-Terminal Domain Dimeration In Outer Membrane Translocation., Lahari Koneru

Electronic Theses and Dissertations

Porphyromonas gingivalis and Tannerella forsythia are two of the primary pathogens that are associated in the etiology and progression of chronic periodontitis. In T. forsythia, KLIKK proteases are the recently identified group of proteolytic enzymes that are secreted through Type IX secretion system (T9SS). Among, these KLIKK proteases a synergistic relationship was observed between karilysin and mirolysin in invading the host complement system for the survival of the bacteria. Since, karilysin has been already characterized, in this study we propose to study about mirolysin through structural, biochemical and biological characterization. The obtained results from the experiments has shown the …

Healthy Teeth: Building Dental Health Awareness Among Head Start Parents, Marisol Cruz

Capstone Projects and Master's Theses

In the U.S and state of California, tooth decay is the most common chronic disease and concerning health issue among children. The Head Start program in Monterey County serves about 1, 245 children annually from birth to five years of age. One requirement is that children obtain dental health checkups every six months, and receive dental treatment, if needed, as part of adhering to California's dental periodicity schedule. Over the past years, an increase of failed dental health assessments was observed among many children enrolled in the program. Obtaining and following through with treatment was an obstacle. The purpose of …

Comparison Of Expression Of The Gdnf Family Neurotrophic Factors In Dental Pulp Stem Cells With Deciduous And Adult Teeth, Kamille Mercado, Nan (Tori) Xiao

All Dugoni School of Dentistry Faculty Articles

The glial cell line-derived neurotrophic factor (GDNF) family has a role in neuron growth within the peripheral and central nervous systems. This makes it a potential therapeutic agent for neurological conditions like Parkinson’s disease and epilepsy. GDNF has also been implicated in murine odontogenesis. In permanent and deciduous human dental pulp stem cells, this study found that GDNF family members and receptors are expressed, indicating neurotrophic factors may play a role in dental pulp regeneration.

Patients’ Willingness To Participate In Rapid Hiv Testing: A Pilot Study In Three New York City Dental Hygiene Clinics, Susan H. Davide, Anthony J. Santella, Winnie Furnari, Petal Leuwaisee, Marilyn Cortell, Bhuma Krishnamachari

Publications and Research

Purpose: One in eight people living with an HIV infection in the United States is unaware of their status. Rapid HIV testing (RHT) is an easily used and accepted screening tool that has been introduced in a limited number of clinical settings. The purpose of this study was to investigate patient acceptability, certainty of their decision, and willingness to pay for screening if RHT was offered in university-based dental hygiene clinics.

Methods: A cross-sectional survey was administered to 426 patients at three dental hygiene clinics in New York City over a period of four months. The survey questionnaire was based …

Pseudomyogenic Hemangioendothelioma: A Vascular Tumor Previously Undescribed In The Oral Cavity, Yeshwant B. Rawal, Kenneth M. Anderson, Thomas B. Dodson

School of Dentistry Faculty Research and Publications

The pseudomyogenic hemangioendothelioma (PMH) is a low-grade malignant vascular neoplasm of different tissue planes including skin and soft tissue. Primary tumors in the skeletal muscle and bone have also been diagnosed. The PMH was introduced into the WHO classification of tumors of soft tissue and bone in 2013. This is the first description of oral involvement. A 21-year-old female presented with a 2-month old swelling of her gingiva. The swelling appeared red in color and was soft in consistency. A clinical diagnosis of a pyogenic granuloma was made and an incisional biopsy was submitted for histopathological evaluation. The lesion consisted …

Divergent Schwannoma-Like Phenotype In A Pleomorphic Adenoma, Srinivasa R. Chandra, Farah Karim, Yeshwant B. Rawal

School of Dentistry Faculty Research and Publications

The schwannoma-like pleomorphic adenoma is a rare histopathological variant of the pleomorphic adenoma. Five previous reports with seven cases exist in English language literature. These tumors present in the parotid gland most commonly. Intraparotid schwannomas of the facial nerve and schwannomas with glandular differentiation have also been reported. A 60-year-old male presented with an asymptomatic swelling over the left angle of the mandible. The swelling had been present for about 12 years with a recent increase in size. CT imaging showed a hyperdense circumscribed mass of the superficial lobe of the parotid. The working diagnosis was that of a benign …

Mineral Particles Stimulate Innate Immunity Through Neutrophil Extracellular Traps Containing Hmgb1., Hsin-Hsin Peng, Yu-Ju Liu, David M. Ojcius, Chiou-Mei Lee, Ren-Hao Chen, Pei-Rong Huang, Jan Martel, John D. Young

All Dugoni School of Dentistry Faculty Articles

Calcium phosphate-based mineralo-organic particles form spontaneously in the body and may represent precursors of ectopic calcification. We have shown earlier that these particles induce activation of caspase-1 and secretion of IL-1β by macrophages. However, whether the particles may produce other effects on immune cells is unclear. Here, we show that these particles induce the release of neutrophil extracellular traps (NETs) in a size-dependent manner by human neutrophils. Intracellular production of reactive oxygen species is required for particle-induced NET release by neutrophils. NETs contain the high-mobility group protein B1 (HMGB1), a DNA-binding protein capable of inducing secretion of TNF-α by a …

Ada News - 11/20/2017, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Ada News - 11/06/2017, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.