Dentistry Commons^™

Microfluidic-Assisted Fabrication Of Reverse Micelle/Plga Hybrid Microspheres For Sustained Vascular Endothelial Growth Factor Delivery, Meisam Omidi, Luis Eduardo Almeida, Lobat Tayebi

School of Dentistry Faculty Research and Publications

In this study, poly (d, l-lactide-co-glycolide) (PLGA) composite microspheres containing anhydrous reverse micelle (R.M.) dipalmitoylphosphatidylcholine (DPPC) nanoparticles loaded vascular endothelial growth factor (VEGF) were produced using microfluidic platforms. The VEGF-loaded R.M. nanoparticles (VRM) were achieved by initial self-assembly and subsequent lipid inversion of the DPPC vesicles. The fabricated VRMs were encapsulated into the PLGA matrix by flow-focusing geometry microfluidic platforms. The encapsulation efficiency, in vitro release profile, and the bioactivity of the produced composite microspheres were investigated. The release study showed that VEGF was slowly released from the PLGA composite microspheres over 28 days with a reduced initial burst (18 …

J Mich Dent Assoc June 2021

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

• A cover story “Team-Based Treatment of Oral Cancer: The U-M Experience”.
• A feature article, “Dental Management of the Head and Neck Cancer Patient Treated with Radiation Therapy: Update 2021”.
• A feature article on “Understanding Cyber Threats and the Risk they Pose to Your Practice”.
• "A Train-the-Trainer Education Model and Rural Dental Opioid Prescribing Outcomes”, a …

The Acquisition Of Dental Competencies And Clinical Skills: Perceptions From Students, Faculty, Practicing Dentists And Industry Professionals In The Dominican Republic, Laura Virginia Reyes Alardo

Dissertations

The Dominican healthcare system faces many challenges, and dental education is not an exception. The lack of competencies established for dentistry is one of the most critical challenges that dentistry faces. There is no way to guarantee that all dentists receive the same quality education with no standards and lack of competencies. Previous research has revealed that the competencies achieved by dental students determine the way such students develop their professional practice in the future as dental graduates (Alcota, De Gauna, & González, 2016). However, there is a lack of shared language observed in dental education around the world. Not …

Mesenchymal Chondrosarcoma Simulating A Periodontal Disease: A Case Report, Adham Fahmy, Abanoub Selim, Yara Youssef, Iman Mostafa, Hala El-Kammar

Future Dental Journal

Mesenchymal chondrosarcoma (MCS) is a rare high-grade variant of chondrosarcoma. MSC`s represent about 1% to 9% of chondrosarcomas. Less than 500 cases of MCS have been reported in literature, so far. As opposed to other variants, MSC develops outside of the bone in almost third of the cases. Pain and swelling are the most common symptoms at presentation. The overall prognosis of MSC is poor, with frequent distant metastases. Histopathologically, MCS typically exhibits a biphasic pattern consisting of both small cells, and islands of atypical cartilage. The immunohistochemical profile of this lesion overlaps with several other entities. Resection with wide …

Evaluation Of Mucograft® In Increasing The Peri-Implant Soft Tissue Thickness In The Esthetic Zone., Sarah Gamal Moussa, Nivine Ibrahim Ragy, Khaled Abdel Ghaffar

Future Dental Journal

Objective: To study the effect of Collagen matrix Mucograft (CM) in enhancing the soft tissue thickness around immediate implants (II) in comparison to palatal connective tissue grafts (SCTG).

Subjects & methods: This randomized, controlled clinical trial included 16 patients, who were randomly divided into test (IIP +CM) and control (IIP+SCTG) groups. Clinical parameters evaluated at baseline, 3-months, and 6-months were papillary bleeding index (PBI), gingival index (GI), facial probing depth (FPD), palatal probing depth (PPD). Direct measurements of gingival thickness were evaluated at baseline and 6-months follow up. Pink esthetic score (PES) and white esthetic score (WES) were evaluated at …

Influence Of Leucocyte Platelet Rich Fibrin (L-Prf) On Guided Tissue Regeneration Using Perforated Membrane (Randomized Clinical Trial), Mariam Samir Nabih, Nivine Ibrahim Ragy, Waleed Abbas Nada, Ahmed Youssef Gamal

Future Dental Journal

Background: Passage of gingival fibroblasts/gingival mesenchymal stem cells through macro-perforated barrier membranes may allow them to contribute positively in periodontal regeneration. The present study was designed to evaluate the effect of use of Leucocyte Platelet Rich Fibrin (L-PRF) on periosteum-derived stem/ progenitor cells (PDPCs) and gingival mesenchymal stem cells (GMSCs) encouraging their passage through membrane perforations. Methods: twenty patients were randomly allocated into two equal groups; Group I perforated membrane (PM): included intrabony defects treated by perforated membranes. Group II Leucocyte-platelet rich fibrin + perforated membrane (L-PRF + PM): included intrabony defects treated by Leucocyte platelet rich fibrin & perforated …

Effect Of Different Surface Treatments On Bond Strength To Tetragonal And Cubic Zirconia, Mohamed Mahmoud Abdelnaby, Moustafa Nabil Aboushelib, Ossama Saleh Abdelghany, Amr El-Etreby

Future Dental Journal

Background: Dental zirconia has been widely used due to its superior mechanical properties. However, traditional etching techniques and surface treatments are generally ineffective on zirconia surfaces due to its inertness and lack of a silica phase. Hence, various surface treatments are applied to improve bonding to zirconia.

Objectives: The aim of this study was to evaluate the effect of three different surface treatments: low pressure air borne particle abrasion, selective infiltration etching and fusion sputtering on bond strength to both Tetragonal zirconia and Cubic zirconia.

Materials and Methods: Ninety two specimens of zirconia were used in this study. Two of …

Evaluation Of Dentin Micro-Hardness And Antibacterial Efficiency Against E.Faecalis After Irrigation With Sodium Hypochlorite Followed By Either Grape Seed Extract Or Edta: A Randomized In -Vitro Study, Yasmeen S. Mahmoud, Dalia A. Saba, Taheya A. Moussa

Future Dental Journal

Objectives: Evaluation of dentin micro-hardness, dentinal erosion and antibacterial efficiency against E.faecalis after irrigation with sodium hypochlorite (NaOCl) followed by grape seed extract (GSE)solution versus irrigation with NaOCl followed by EDTA.

Materials and Methods: Regarding dentin micro-hardness test; 16 teeth were divided into 2 groups; intervention (5.25%NaOCl+13%GSE) and comparator (5.25%NaOCl+17%EDTA) groups. Each tooth was decoronated and sectioned vertically. Dentin microhardness was evaluated before and after irrigation at the coronal, middle and apical thirds. Representative specimens from the micro-hardness test were used for dentin surface examination using scanning electron microscope (SEM). For the evaluation of the antibacterial efficiency, 18 teeth were …

Assessment Of Efficacy Of Photoactivated Disinfection Versus Calcium Hydroxide Disinfection In Regeneration Of Immature Infected Teeth - A Comparative In Vivo Study., Kholoud Mohamed Emam, Kariem El-Batouty Professor At Endodontic Department, Mohamed Mokhtar Nagy Ass. Professor At Endodontic Department

Future Dental Journal

Aim: To study the effectiveness of photo activated disinfection (PAD) Disinfection Versus Calcium Hydroxide Disinfection in Regeneration of Immature Infected Teeth. Material and Methods:30 patients with immature, single rooted teeth appearing with or without signs and/or symptoms of periapical pathology were involved in the study. Cases were classified into three groups according to the disinfection protocol, ten patients each group (n=10). Group I: Calcium hydroxide (Ca (OH)) was injected in the canal after drying the canal with sterile paper points. Group II: Photosensitizers (Azulenocyanine) was inserted in the canals and agitated in the canal, then activated with diode …

Maintaining Root Canal Curvatures After Preparation With Different Nickel-Titanium Rotary Systems (A Comparative In Vitro Study), Wael Betbout, Mohammad Al Shammaa, Roula S. Abiad

BAU Journal - Creative Sustainable Development

The ongoing advancement of materials and methods for root canal instrumentation is resulting in improved techniques with minimal variations to the canal morphology. One standard for assessment of the shaping quality of curved root canals is preparation-induced straightening of the canal. The aim of the study: To compare the effects of 2 Nickel-Titanium rotary systems, 2Shape (Micro-Mega, Besançon, France) and ProTaper Next (Dentsply,Sirona, Ballaigues, Switzerland), on maintaining the distobuccal canals curvature of extracted human maxillary molar teeth using periapical radiographs. Materials and methods: In this study a total of 26 distobuccal roots of upper maxillary molars were used and divided …

Laser-Assisted Tooth Extraction In Patients With Impaired Hemostasis, Elena Larionova Dr., Ekaterina Diachkova Dr., Elena Morozova Prof., Albert Davtyan Dr., Svetlana Tarasenko Prof.

BioMedicine

Introduction: The provision of efficient dental care to patients with hemostatic disorders is tied to difficulties and problems such as prolonged bleeding after or during surgical manipulation.

Aim: This study aims to increase the efficiency of oral surgery in patients with thrombocytopenia with the use of erbium laser on different stages of tooth extraction.

Methods: Patients (n = 96) were selected for tooth extraction on an outpatient basis: patients with confirmed thrombocytopenia (age 44 ± 15.4, 19–74) were included in the 1st group, and patients without impaired hemostasis (age 47.6 ± 15.3, 19¬81) were included in the …

Reprogramming Oral Epithelial Keratinocytes Into A Pluripotent Phenotype For Tissue Regeneration, Fayrouz Bazina, Sabine M. Brouxhon, Stephanos Kyrkanides

Center for Oral Health Research Faculty Publications

OBJECTIVES: We set out to reprogram adult somatic oral epithelial keratinocytes into pluripotent cells for regenerative dentistry.

SETTING AND SAMPLE POPULATION: Immortalized murine oral keratinocyte cell (IMOK) line raised from adult mouse mucosa were cultured in vitro in our studies.

MATERIALS AND METHODS: Adult murine oral epithelial keratinocytes were chronically treated with TGF-β1 in vitro, and the expression of Oct4, Nanog, Sox2 and Nestin, as well as specific homeobox Gata and Pax gene family members were investigated.

RESULTS: We documented the induction of stem factors linked with pluripotency and/or the maintenance and regulation of stem-cell self-renewal in oral epithelial keratinocytes …

Tissue Reaction To Novel Customized Calcium Silicate Cement Based Dental Implants. A Pilot Study In The Dog, Amir Fakhrzadeh, Mohammad A. Saghiri, Steven M. Morgano, Andrew Sullivan

All Dugoni School of Dentistry Faculty Articles

Objectives: The purpose of this study was to determine the level of periodontal tissue regeneration in a canine model following post-extraction placement of an implant molded from a composite material made from extracted tooth dentin and a calcium silicate cement (CSC) material. The investigation used autologous dentin in conjunction with a CSC material to form a composite implant designed for immediate tooth replacement. Methods: Two (2) beagles had a periodontal and radiographic examination performed to rule out any pre-treatment inflammation, significant periodontal disease, or mobility. Then, ination eleven (11) teeth were extracted and polyvinyl siloxane molds were made to fabricate …

Efficacy Of Hand Instrumentation Vs Power Instrumentation, Khrystyna Vyprynyuk, Annie Chitlall

Publications and Research

Dental hygienists face many challenges as they practice during a global pandemic. The strict implementation of a variety of new infection control guidelines needed to prevent the transmission of SARS-CoV-2 has changed the way many oral health professionals practice. On June 9, 2020, the American Dental Association’s (ADA) Advisory Task Force on Dental Practice Recovery issued guidelines that included the preferred use of hand instrumentation over ultrasonic instrumentation for plaque and calculus removal to reduce aerosol production.

As many clinicians are accustomed to using power instrumentation during periodontal therapy, this article will examine the effectiveness of hand instrumentation in the …

International Journal Of Dentistry, Ahmed Hamdy, Dalia Ghalwash, Waleed M. Abbas, Hala K. Abd El Gaber

Dentistry

Objectives. This study aimed to clinically assess and compare the width of peri-implant keratinized mucosa following the use of a readymade plastic stent with apically repositioned flap versus conventional apically repositioned flap with papillary sparing incisions during single-stage implant placement protocol. Materials and Methods. A total of 20 patients were enrolled in this study. In the test group, a prefabricated implant-retained stent was clipped on the healing abutment after implant surgery to reposition the keratinized tissue buccoapically. In the control group, simple interrupted sutures were applied instead of using a stent. After the surgical procedure, the width of …

An Update On Cardiovascular Disease, Susan H. Davide, Audra E. Haynes

Publications and Research

In the United States, cardiovascular is the leading cause of death in men and women, and most racial and ethnic groups. There are several types of heart conditions; the most common type is coronary heart disease, also known as coronary artery disease or ischemic heart disease, which can cause acute myocardial infarction. Other heart conditions which can lead to heart failure include a past history of myocardial infarction, abnormal heart valves, heart muscle disease, or congenital heart muscle disease. In adults ages 65 and younger, approximately 2 in 10 deaths are caused from coronary artery disease and about 18.2 million …

The Moth-Eaten Mandible: Osteomyelitis, Galal Omami

Oral Health Practice Faculty Publications

Inflammatory lesions such as osteomyelitis of the jaw may share some of the radiographic features of malignancy; however, a demonstrable dental cause for it usually exists. In addition, inflammatory lesions generally stimulate a sclerotic bone reaction, which is uncommon in malignancy. The imaging modality of choice for aiding in the differential diagnosis is computed tomography imaging because of its ability to clearly delineate sequestra and periosteal new bone formation.

Knowledge, Protective Behaviors And Risk Perception Of Covid-19 Among Dental Students In India: A Cross-Sectional Analysis, Kavita Batra, Yashashri Urankar, Ravi Batra, Aaron F. Gomez, Meru S., Pragati Kaurani

School of Medicine Faculty Research

Objective: This study’s objective was to examine the knowledge, performance in practicing protective behaviors, and risk perception of Coronavirus disease-19 (COVID-19) among dental students of India. Methods: A web-based cross-sectional survey was conducted from 10–30 August 2020, involving 381 dental students that were enrolled at the Uttaranchal Dental and Medical Research Institute in India. A web-based structured questionnaire assessed the COVID-19 related knowledge, protective behaviors, and risk perception performance. The independent-samples-t and analysis of variance tests were used to analyze the differences in knowledge, protective behaviors, and perception across the groups. Results: Of the dental students surveyed, 83% had adequate …

Ada News - 05/10/2021, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Photobiostimulatory Effect Of A Single Dose Of Low-Level Laser On Orthodontic Tooth Movement And Pain, Irfan Qamruddin, Mohammad Khursheed Alam, Verda Mahroof, Mubassar Fida, Mohd Fadhli Khamis, Adam Husein

Section of Dental-Oral Maxillofacial Surgery

Objective: To assess the effect of low-level laser applied at 3 weeks intervals on orthodontic tooth movement (OTM) and pain using conventional brackets (CB).
Materials and methods: Twenty patients with Angle's class II div 1 (10 males and 10 females; aged 20.25 ± 3.88 years) needing bilateral extractions of maxillary first bicuspids were recruited. Conventional brackets MBT of 0.022 in slot (McLaughlin Bennett Trevisi) prescription braces (Ortho Organizers, Carlsbad, Calif) were bonded. After alignment and levelling phase, cuspid retraction began with nitinol closed coil spring on 19 × 25 stainless steel archwire, wielding 150 gram force. 7.5 J/cm² energy …