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Gingival Crevicular Flow (Volume) As A Biomarker Of Orthodontic Tooth Movement, Harrison Truman, Nina Stevens, Tyler Starley 2023 University of the Pacific

Gingival Crevicular Flow (Volume) As A Biomarker Of Orthodontic Tooth Movement, Harrison Truman, Nina Stevens, Tyler Starley

Excellence Day

Tooth movement is caused by the application of force. In short, applied force strains structures present in the PDL space – cells, ligaments, blood vessels. Cells in the PDL are damaged by extension and by diminished oxygen supply due to compression of blood vessels. Compounds released from damaged or dead cells trigger an innate inflammatory response. One of the biomarkers of that response is increased formation of extracellular fluid (edema), specifically gingival crevicular fluid (GCF). Our goal is to monitor changes of GCF flow during the orthodontic treatment with Invisalign.


Hazardous Noise Level Measured In A Dental Clinic: A Comprehensive Study, Isabella P. Gantman, Nico Scordakis, Samantha Rodriguez, Emily Bernard, Bina Surti, Karen A. Schulze, Fadi Najem, Joing Hu 2023 University of the Pacific

Hazardous Noise Level Measured In A Dental Clinic: A Comprehensive Study, Isabella P. Gantman, Nico Scordakis, Samantha Rodriguez, Emily Bernard, Bina Surti, Karen A. Schulze, Fadi Najem, Joing Hu

Excellence Day

This project intends to determine the amount of long term noise exposure to dentists in the modern-day dental environment. By systematically conducting noise collection within a standard dental environment, the institution can identify ways to minimize the amount of noise within the dental environment. This will provide new instruments and or resources to dentists to mitigate the overall risk of dental health professionals in relation to hearing loss over time.


Screw Loosening In Cast-To-Ucla Abutment Versus Cad-Cam Abutment Design In Last Five Years: A Retrospective Cohort Study, Jasdeep Kaur Cheema, Steven Sadowsky 2023 University of the Pacific

Screw Loosening In Cast-To-Ucla Abutment Versus Cad-Cam Abutment Design In Last Five Years: A Retrospective Cohort Study, Jasdeep Kaur Cheema, Steven Sadowsky

Excellence Day

In recent years, the use of screw retained implant supported prostheses has increased compared with cement-retained designs because of its biological advantages and retrievability. The UCLA castable abutment has been the mainstay for screw-retained porcelain fused to metal (PFM) implant crowns. It consists of a plastic cylinder that connects to the abutment which can be customized by waxing and casting using base or noble metal alloy. While PFM implant crowns using the UCLA abutment allows for minimal interocclusal space (5 mm) unlike other screw-retained designs, it has been linked to increase in mechanical complications such as screw loosening and screw …


Comparison Of Zirconia And Lithium Disilicate As A Restorative Material, Jemima Chatla, Urvi Sanghvi, Elham Shakeri 2023 University of the Pacific

Comparison Of Zirconia And Lithium Disilicate As A Restorative Material, Jemima Chatla, Urvi Sanghvi, Elham Shakeri

Excellence Day

Background: Zirconia and Lithium disilicate have been widely utilized in dental restorations for both partial and full coverage procedures, employing monolithic and layered methods. Objective: The aim of this literature review was to assess these materials and compare them based on various criteria, such as tooth preparation, bonding techniques, optical and mechanical properties, clinical performance, biocompatibility, marginal fit and adaptation. Additionally, this review also compared the clinical applications of these materials in different types of restorations including full and partial coverage restorations, implants, fixed partial dentures, and endocrowns.


Accuracy Of 3-D Automated Landmark Identification On Cone-Beam Computed Tomography, Joyce Choi, Jake Nealon 2023 University of the Pacific

Accuracy Of 3-D Automated Landmark Identification On Cone-Beam Computed Tomography, Joyce Choi, Jake Nealon

Excellence Day

To evaluate the accuracy of a fully automated landmark identification (ALI) system as a tool for automatic landmark location compared with human judges. Materials and


Traditional Vs Resin Cements For Indirect Restorations, Parveena Ganesh, Dhruvesh Gupta, Parveen Poliki, Tanvir Singh 2023 University of the Pacific

Traditional Vs Resin Cements For Indirect Restorations, Parveena Ganesh, Dhruvesh Gupta, Parveen Poliki, Tanvir Singh

Excellence Day

Indirect restorations, such as inlays, onlays, crowns, and bridges, require a reliable cementation method to ensure long-term success. Aim of this literature is to compare various cementation options that are available, advantages and disadvantages of different materials using conventional cementation or adhesive cementation .Also this discusses the rationale in selecting the choice and techniques in different clinical situations. In conclusion, both traditional and resin cements have their advantages and disadvantages for indirect restoration cementation. The choice of cement type depends on the clinical situation and the preferences of the clinician. Traditional cements may be preferred in situations where high bond …


Replacement Of Missing Teeth: Fpd Vs Implants Vs Removable Prostheses, Pooja Bashyal, Andrew Lee, Maninder Singh 2023 University of the Pacific

Replacement Of Missing Teeth: Fpd Vs Implants Vs Removable Prostheses, Pooja Bashyal, Andrew Lee, Maninder Singh

Excellence Day

This literature review strives to understand different treatment modalities for replacing missing teeth, specifically, considerations for choosing between implants, bridges, and removable dentures.


Treatment Of Deep Bite Using Clear Aligner Therapy, Robert Zhou, Mahban Zarei 2023 University of the Pacific

Treatment Of Deep Bite Using Clear Aligner Therapy, Robert Zhou, Mahban Zarei

Excellence Day

Background: Deep bite is a type of malocclusion that can lead to problems with bite, mastication, speech, and has the potential to damage teeth and gums. While conventional orthodontic treatments have been shown to be effective in addressing this condition, the use of clear aligners for this purpose has not been fully explored in the current scientific literature. Objective: The objective of this retrospective longitudinal study is to evaluate the treatment effects of clear aligners in patients with deep bite malocclusion by examining the dental and skeletal changes between the initial and final treatment time points. Our null hypothesis states …


Adhesion And Minimally Invasive Dentistry, Sana Mohd, Javid Shaikh, Vidhi Bhuva, Vishwash Patel 2023 University of the Pacific

Adhesion And Minimally Invasive Dentistry, Sana Mohd, Javid Shaikh, Vidhi Bhuva, Vishwash Patel

Excellence Day

G. V. Black, the father of modern dentistry believed in extension for prevention. Today we have come a long way. We practice minimally invasive dentistry which is possible because of adhesion. We have eight generations of bonding systems. 4th generation is the gold standard, while 6th ,7th and 8th are used extensively. Direct restorations which involve minimally invasive procedure alternatives for carious lesion management, include the use of sealants, infiltration, atraumatic restorative treatment (ART), and selective carious tissue removal (e.g., indirect pulp capping, stepwise removal, or selective removal to soft dentine). Due to adhesion and the invention of higher quality …


A Review Of External Cervical Resorption, Sarah Makkiyah, Max Kazantcev 2023 University of the Pacific

A Review Of External Cervical Resorption, Sarah Makkiyah, Max Kazantcev

Excellence Day

Invasive cervical resorption (ECR) is a complex form of external resorption. It is distinguished by its localization, its invasive nature, and the formation of a mineralized replacement tissue resembling cellular cementum. During initiation of ECR, the portal of entry is the cementum below the gingival epithelium, and resorption starts with localized destruction and removal of PDL. Response to PDL injury includes formation of a blood clot and inflammation, followed by granulation tissue, recruitment of macrophages, and multinucleated-cell differentiation.


Three-Dimensional Analysis Of Nasoalveolar Molding Treatment (Nam) Effects In Unilateral Cleft Lip, Alveolus, And Palate Patients, Sophie DiPietro, Meghan Hansen, Yoon Weon Suh 2023 University of the Pacific

Three-Dimensional Analysis Of Nasoalveolar Molding Treatment (Nam) Effects In Unilateral Cleft Lip, Alveolus, And Palate Patients, Sophie Dipietro, Meghan Hansen, Yoon Weon Suh

Excellence Day

Background: NAM therapy is a non-surgical method that aims to improve both the aesthetic and functional outcomes of cleft lip and palate treatment in newborns. It applies controlled pressure to the cleft region, allowing for the reshaping of the area. However, further research is necessary to gain a deeper understanding of the underlying factors that influence cleft palate closure patterns and identify the regions that play the most significant role in approximating clefts. Objective: The aim of this study was to assess the impact of pre-surgical nasoalveolar molding (NAM) on infants with unilateral cleft lip and palate, with a hypothesis …


3d Printing In Restorative Dentistry, Sucharu Ghosh, Mahban Zarei, Parul Kumar, Priya Prasannakumar, Patrick Pansoy 2023 University of the Pacific

3d Printing In Restorative Dentistry, Sucharu Ghosh, Mahban Zarei, Parul Kumar, Priya Prasannakumar, Patrick Pansoy

Excellence Day

The term 3 D printing is generally used to describe a manufacturing approach that builds objects one layer at a time, adding multiple layers to form an object The presentation aims to provide a comprehensive understanding of the use of 3 D printing technology in restorative dentistry and its potential impact on the field


Human Dental Pulp Stem Cell Culture Model For Studies On Etiopathogenesis Of Nonsyndromic Cleft Lip With Or Without Cleft Palate Anomaly, Tyler Starley, Jonathan Starley, Harrison Truman 2023 University of the Pacific

Human Dental Pulp Stem Cell Culture Model For Studies On Etiopathogenesis Of Nonsyndromic Cleft Lip With Or Without Cleft Palate Anomaly, Tyler Starley, Jonathan Starley, Harrison Truman

Excellence Day

Nonsyndromic cleft lip with or without cleft palate (NSCLP) occurs approximately in 1 of 700 live births. It has a serious impact on a patient during the whole life. It was shown that it can be prevented by supplementation of folic acid. However, much more needs to be known about etiopathogenetic factors and molecular mechanisms leading to NSCLP in order to personalize its prevention. Basic science information on etiology and pathogenesis of NSCLP was obtained from animal experiments. Clinical studies and trials showed efficacy of prevention by folic acid supplementation. A cell culture model is needed for studies on cellular …


Conventional Vs Digital Impressions, Vinitha Gopal-Murthy, Mirna Merhi-Boghossian, Geet Shukla 2023 University of the Pacific

Conventional Vs Digital Impressions, Vinitha Gopal-Murthy, Mirna Merhi-Boghossian, Geet Shukla

Excellence Day

Summary: A dental impression is a negative replica of the hard and soft tissues of the oral cavity. Conventional impressions help make dental casts which are used for diagnostic and therapeutic purposes. Digital impression involves a 3D intraoral scanning, which is processed by the impression involves a 3D intraoral scanning, which is processed by the computer to generate a virtual replica of the tissues in the mouth. In siloxanes, poly sulfides, addition and condensation silicones are used. Digital impressions can be a closed system like CEREC, that relies on one manufacturer and technology for CAD/CAM procedures or open systems like …


Comparison Of Various Post-Systems In Endodontically Treated Teeth, Viraj Ketkar, Hemal Pandya, Fariba Yaghoobi 2023 University of the Pacific

Comparison Of Various Post-Systems In Endodontically Treated Teeth, Viraj Ketkar, Hemal Pandya, Fariba Yaghoobi

Excellence Day

Summary: This study aims to compare various post-systems used in endodontically treated teeth. A comprehensive literature review was conducted to identify studies that compared different post systems in endodontically treated teeth. The inclusion criteria included studies comparing two or more post-systems regarding clinical and/or radiographic outcomes. The studies included in the review evaluated different types of post systems, including prefabricated metal posts, custom-made metal posts, fibre-reinforced posts, and zirconia posts. The outcomes evaluated included retention rates, fracture rates, and marginal adaptation. Cast posts offer customization benefits but need multiple appointments, while prefabricated posts are widely used for their various material, …


The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In The Oral Cavity – A Preliminary Literature Review, Youyoung Min 2023 University of the Pacific

The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In The Oral Cavity – A Preliminary Literature Review, Youyoung Min

Excellence Day

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been suggested to replicate and be found in the oral cavity. The objective of this preliminary literature review is to determine the effects of cigarette smoke on the risk of SARS-CoV-2 infection in the oral cavity, and the risk for the overall health. SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), uses the ACE2 receptor and protease TMPRSS2 for entry into host cells. The cigarette smoke condensates upregulates these receptors in human gingival epithelial cells. Because smoking can alter expression of COVID-19 viral entry genes, smokers are more susceptible to SARS-CoV-2 infection. Several …


Insight - Summer 2023, Dugoni School of Dentistry 2023 University of the Pacific

Insight - Summer 2023, Dugoni School Of Dentistry

Insight

Welcome to the summer 2023 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.


Report: North Dakota Department Of Health Oral Health Program: Full Evaluation Of The Oral Health Program’S Activities Under Centers For Disease Control And Prevention (Cdc) Grant, State Actions To Improve Oral Health Outcomes, Shawnda Schroeder 2023 University of North Dakota

Report: North Dakota Department Of Health Oral Health Program: Full Evaluation Of The Oral Health Program’S Activities Under Centers For Disease Control And Prevention (Cdc) Grant, State Actions To Improve Oral Health Outcomes, Shawnda Schroeder

Indigenous Health Faculty Publications

The Mission of the North Dakota Department of Health (ND DoH) Oral Health Program (OHP) is to improve the oral health of all North Dakotans through prevention and education. Funding from the Centers for Disease Control and Prevention (CDC) State Actions to Improve Oral Health Outcomes enables the OHP to implement oral health promotion and prevention activities that address targeted need within the state. Component one of the grant addresses oral health disparities by both maintaining the existing public health capacity among the OHP, and identifying, implementing, evaluating, and disseminating best practices for oral health promotion and disease prevention among …


The Emerging Oral Pathogen, Filifactor Alocis, Modulates Antimicrobial Responses In Primed Human Neutrophils., Ian J. Snider 2023 University of Louisville

The Emerging Oral Pathogen, Filifactor Alocis, Modulates Antimicrobial Responses In Primed Human Neutrophils., Ian J. Snider

College of Arts & Sciences Senior Theses

Periodontitis is an irreversible, chronic inflammatory, infectious disease of the oral cavity that affects approximately half of all adults 30 years or older in the USA. The oral cavity is under high immune surveillance because of its constant exposure to microbes in the environment. The primary immune cell responsible for this surveillance is the neutrophil. Pathogens associated with periodontitis possess virulence factors and have evolved strategies to evade neutrophil antimicrobial responses to survive. One such pathogen is Filifactor alocis, whose presence is associated with the progression of periodontitis. F. alocis manipulates several neutrophil antimicrobial functional responses to avoid killing, an …


Molar Macrowear As A Proxy For Age In A Captive Sample Of Papio Hamadryas, Lauren Conrad 2023 University of Arkansas, Fayetteville

Molar Macrowear As A Proxy For Age In A Captive Sample Of Papio Hamadryas, Lauren Conrad

Biological Sciences Undergraduate Honors Theses

This study is methods-focused, centering around molar crown macrowear and its performance as a proxy for age in a sample of pedigreed, non-human primates. It analyzes the correlation between age-structured variables and molar wear among both males and females in a captive group of baboons. Here, I examined whether wear is significantly correlated with age-related variables (i.e., generations/cohorts) and whether the structure of the “age” dataset differed across wear categories. Because chronological age is unknown, I used documented pedigrees and parent-offspring relationships to group individuals into possible generations. I then used dental development charts to group individuals into cohorts based …


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