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Does Beta-Alanine Supplementation Potentiate Muscle Performance Following 6 Weeks Of Blood Flow Restriction Or Traditional Resistance Training?, Kassiana de Araujo Pessoa, Jason Michael Cholewa, Rayssa Sousa-Silva, Xia Zhi, Alessandro M. Zagatto, Antonio Herbert Lancha-Jr, Jakob D. Lauver, Fabricio Eduardo Rossi, NELO ZANCHI 2023 Federal University of Maranhao

Does Beta-Alanine Supplementation Potentiate Muscle Performance Following 6 Weeks Of Blood Flow Restriction Or Traditional Resistance Training?, Kassiana De Araujo Pessoa, Jason Michael Cholewa, Rayssa Sousa-Silva, Xia Zhi, Alessandro M. Zagatto, Antonio Herbert Lancha-Jr, Jakob D. Lauver, Fabricio Eduardo Rossi, Nelo Zanchi

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 999-1011, 2023. We aimed to compare the effects of beta-alanine on Traditional Resistance Training (TRAD) or Blood Flow Restriction Training (BFR). Methods: 19 subjects were randomly allocated to a Placebo (n = 10) or beta-alanine (n = 9) group. Subjects from both groups were trained unilaterally (unilateral arm curl) for six weeks, and each arm was trained using a different paradigm (BFR or TRAD). One repetition maximum (1RM) test measurements were performed before and after the strength training program. Work output was accessed as the total weight lifted (repetitions × weight lifted …


A New, Simple And Practical Approach To Increase The Effects Of Aerobic Exercise On Serum Levels Of Neurotrophic Factors In Adult Males, Mahdi Bahramnejad, Vahid Valipour Dehnou, Rasoul Eslami 2023 Sports Sciences Department, Faculty of Literature & Human Sciences, Lorestan University, Khorramabad, Iran

A New, Simple And Practical Approach To Increase The Effects Of Aerobic Exercise On Serum Levels Of Neurotrophic Factors In Adult Males, Mahdi Bahramnejad, Vahid Valipour Dehnou, Rasoul Eslami

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 932-941, 2023. Environmental enrichment (EE) is defined as a combination of complex inanimate and social stimulation. Physical activity and EE may augment the beneficial effects of each other. This study aimed to assess the effects of running in an enriched environment on neurotrophic factors in adult males. Twelve volunteer adult males (age 26.75 ± 5.34 yrs, body mass 70.72 ± 8.61 kg, height 172.50 ± 5.68 cm, VO2max 56.8 ± 2.93) completed two sessions, each consisted of one hour of running at an intensity of 12-13 on the Borg Scale. One session was …


Performance Kinetics During Repeated Sprints Is Influenced By Knowledge Of Task Endpoint And Associated Peripheral Fatigue, François Billaut, Marie R. Demers, Andrew Hibbert 2023 Université Laval

Performance Kinetics During Repeated Sprints Is Influenced By Knowledge Of Task Endpoint And Associated Peripheral Fatigue, François Billaut, Marie R. Demers, Andrew Hibbert

International Journal of Exercise Science

International Journal of Exercise Science 16(1): 987-998, 2023. The regulation of exercise intensity allows an athlete to perform an exercise in the fastest possible time while avoiding debilitating neuromuscular fatigue development. This phenomenon is less studied during intermittent activities. To investigate anticipatory and real-time regulation of motor output and neuromuscular fatigue during repeated-sprint exercise, twelve males randomly performed one (S1), two (S2), four (S4) and six (S6) sets of five 5-s cycling sprints. Mechanical work and electromyographic activity were assessed during sprints. Potentiated quadriceps twitch force (ΔQtw,pot) and central activation ratio (QCAR) were quantified from response …


The Effects Of Postural Education Or Corrective Exercise On The Craniovertebral Angle In Young Adults With Forward Head Posture: A Randomized Controlled Trial, David A. Titcomb, Bridget F. Melton, Theresa Miyashita, Helen W. Bland 2023 Liberty University

The Effects Of Postural Education Or Corrective Exercise On The Craniovertebral Angle In Young Adults With Forward Head Posture: A Randomized Controlled Trial, David A. Titcomb, Bridget F. Melton, Theresa Miyashita, Helen W. Bland

International Journal of Exercise Science

International Journal of Exercise Science 16(1): 954-973, 2023. The purpose of this study was to compare the effects of three different intervention strategies, postural education (PE) and two corrective exercise programs (CEPs), on the craniovertebral angle (CVA) in young adults with forward head posture (FHP). A prospective four-arm parallel randomized controlled trial with repeated measures was performed. Seventy-nine healthy young adults (55 women, 24 men; mean age: 20.08 ± 2.19 years) with FHP were randomized into four groups: PE group, self-myofascial release + stretching group (SMRS), self-myofascial release + stretching + strengthening group (SMRSS), and a control group (CG). Participant …


Increasing Trunk Mass Evokes Lower Extremity Biomechanical Plasticity During Stair Descent, Alexis Nelson, Hailey Fong, Alex Carnall, Melissa J. Puppa, Derek Beeler, Cris Stickley, William M. Mihalko, Douglas W. Powell 2023 University of Tennessee Health Science Center

Increasing Trunk Mass Evokes Lower Extremity Biomechanical Plasticity During Stair Descent, Alexis Nelson, Hailey Fong, Alex Carnall, Melissa J. Puppa, Derek Beeler, Cris Stickley, William M. Mihalko, Douglas W. Powell

International Journal of Exercise Science

International Journal of Exercise Science 16(1): 942-953, 2023. The purpose of this study was to investigate the influence of simulated changes in body mass on lower extremity joint work and relative joint contributions during stair descent. Ten healthy recreationally active college-age participants performed five stair descent trials in each of five loading conditions: no added load and with an additional 5%, 10%, 15% and 20% of their body weight. Three-dimensional ankle, knee and hip joint powers were calculated using a six degree-of-freedom model in Visual3D (C-Motion Inc., Germantown, MD, USA). Sagittal plane joint work was calculated as the joint power …


The Importance Of Contrast Sensitivity, Color Vision, And Electrophysiological Testing In Clinical And Occupational Settings, Frances Silva 2023 University of the Incarnate Word

The Importance Of Contrast Sensitivity, Color Vision, And Electrophysiological Testing In Clinical And Occupational Settings, Frances Silva

Theses & Dissertations

Visual acuity (VA) is universally accepted as the gold standard metric for ocular vision and function. Contrast sensitivity (CS), color vision, and electrophysiological testing for clinical and occupational settings are warranted despite being deemed ancillary and minimally utilized by clinicians. These assessments provide essential information to subjectively and objectively quantify and obtain optimal functional vision. They are useful for baseline data and monitoring hereditary and progressive ocular conditions and cognitive function. The studies in this dissertation highlight the value of contrast sensitivity, color vision, and cone specific electrophysiological testing, as well as the novel metrics obtained with potential practical clinical …


Microglial Response To Glucocorticoids During Chronic Sleep Fragmentation, Christian Chelson 2023 Western Kentucky University

Microglial Response To Glucocorticoids During Chronic Sleep Fragmentation, Christian Chelson

Masters Theses & Specialist Projects

Sleep is one of the body’s greatest and most basic needs. Chronic sleep loss (<6 hours a day) is linked to many cardiovascular issues, diabetes, and inflammatory conditions and has been shown to lower life expectancy. Obstructive sleep apnea (OSA) is a complication that causes sleep fragmentation in >8% of adults from developed countries, and many with OSA may be unaware of their condition. Having long-term OSA is linked to neuroinflammation caused by activated microglia in the brain, but the mechanics of this inflammation are not well understood. It is known that glucocorticoids, steroid hormones produced and released from the adrenal glands, have a suppressive effect on microglia. The purpose of this study is to explore the role that glucocorticoids have upon microglia activation induced by chronic sleep fragmentation (SF). C57BL/6J mice were …


Behavioral Response To Conspecific Sounds In Loricariid Catfishes (Pterygoplichtys Pardalis And Otocinclus Vittatus), Hephzibah Obafunmiso 2023 Western Kentucky University

Behavioral Response To Conspecific Sounds In Loricariid Catfishes (Pterygoplichtys Pardalis And Otocinclus Vittatus), Hephzibah Obafunmiso

Masters Theses & Specialist Projects

Sound production is a means of communication among many fish species. In fishes, sound is produced through various mechanisms, but in the family Loricariidae, known as armored suckermouth catfishes, sound is produced primarily through pectoral fin spine stridulation. Previous experiments have described the sounds produced and shown the mechanism of sound production in two species of loricariid catfishes, Pterygoplichthys gibbiceps and Otocinclus affinis, but the functional significance of loricariid sounds is still unknown. To address this question, I examined the behavioral responses of Pterygoplichthys pardalis and Otocinclus vittatus to conspecific calls. Individual fish (N=10 for P. pardalis) or groups …


Effects Of Chewing Time On Gastrointestinal Discomfort, Substrate Use, And Performance During Running, Thomas Geaney 2023 Old Dominion University

Effects Of Chewing Time On Gastrointestinal Discomfort, Substrate Use, And Performance During Running, Thomas Geaney

Human Movement Studies & Special Education Theses & Dissertations

Previous research has shown that food particle size affects gastric processing. For example, food particles greater than 3 mm may delay gastric emptying under certain conditions. Delays in gastric emptying can be problematic during aerobic exercise, leading to nausea, bloating, fullness, and other gastrointestinal (GI) symptoms. In some cases, symptoms can be severe enough to negatively affect athletic performance. This study investigated the effects of manipulating chewing duration of carbohydrate sports bars on GI discomfort, physiological responses, and performance during endurance running. This crossover study recruited 12 male runners (age: 36.4 ± 7.2 years, VO2peak: 57.2 ± 4.7 …


Shedding In The Timber Rattlesnake: Natural Patterns, Endocrinological Underpinnings, Temporal And Energetic Effort, And Integration As A Reptilian Life History Trait, Maxwell D. Carnes-Mason 2023 University of Arkansas, Fayetteville

Shedding In The Timber Rattlesnake: Natural Patterns, Endocrinological Underpinnings, Temporal And Energetic Effort, And Integration As A Reptilian Life History Trait, Maxwell D. Carnes-Mason

Graduate Theses and Dissertations

The semi-frequent replacement of the epidermis (ecdysis) is a characteristic trait of reptiles. Whereas all reptiles regularly engage in some degree of skin shedding, skin morphology in snakes necessitates the synchronous replacement of the entire epidermis and facilitates the subsequent removal of the old layer as a single sheet. To date, the ubiquitous process has garnered little attention from researchers because snakes shed with unpredictable timing and frequency and are exceedingly cryptic during ecdytic cycles; previously impeding detailed physiological or ecological investigations of the process in the clade. Because of the lack of study, ecdysis is often viewed as a …


Fructose Induced Khk-C Can Increase Er Stress Independent Of Its Effect On Lipogenesis To Drive Liver Disease In Diet-Induced And Genetic Models Of Nafld, Se-Hyung Park, Robert N. Helsley, Taghreed Fadhul, Jennifer L. S. Willoughby, Leila Noetzli, Ho-Chou Tu, Marie H. Solheim, Shiho Fujisaka, Hui Pan, Jonathan M. Dreyfuss, Joanna Bons, Jacob Rose, Christina D. King, Birgit Schilling, Aldons J. Lusis, Calvin Pan, Manoj Gupta, Rohit N. Kulkarni, Kevin Fitzgerald, Philip A. Kern, Senad Divanovic, C. Ronald Kahn, Samir Softic 2023 University of Kentucky

Fructose Induced Khk-C Can Increase Er Stress Independent Of Its Effect On Lipogenesis To Drive Liver Disease In Diet-Induced And Genetic Models Of Nafld, Se-Hyung Park, Robert N. Helsley, Taghreed Fadhul, Jennifer L. S. Willoughby, Leila Noetzli, Ho-Chou Tu, Marie H. Solheim, Shiho Fujisaka, Hui Pan, Jonathan M. Dreyfuss, Joanna Bons, Jacob Rose, Christina D. King, Birgit Schilling, Aldons J. Lusis, Calvin Pan, Manoj Gupta, Rohit N. Kulkarni, Kevin Fitzgerald, Philip A. Kern, Senad Divanovic, C. Ronald Kahn, Samir Softic

Saha Cardiovascular Research Center Faculty Publications

Non-alcoholic fatty liver disease (NAFLD) is a liver manifestation of metabolic syndrome, and is estimated to affect one billion individuals worldwide. An increased intake of a high-fat diet (HFD) and sugar-sweetened beverages are risk-factors for NAFLD development, but how their combined intake promotes progression to a more severe form of liver injury is unknown. Here we show that fructose metabolism via ketohexokinase (KHK) C isoform leads to unresolved endoplasmic reticulum (ER) stress when coupled with a HFD intake. Conversely, a liver-specific knockdown of KHK in mice consuming fructose on a HFD is adequate to improve the NAFLD activity score and …


The Role Of E-Liquid Constituents In E-Cigarette-Induced Cardiac Arrhythmia And Autonomic Imbalance., Cory Kucera 2023 University of Louisville

The Role Of E-Liquid Constituents In E-Cigarette-Induced Cardiac Arrhythmia And Autonomic Imbalance., Cory Kucera

Electronic Theses and Dissertations

Introduction. Accumulating evidence indicates that exposure to electronic cigarettes (e-cigs) promotes sympathetic dominance and electrophysiologic instability in the heart, potentially culminating in arrhythmogenesis. E-liquids contain various formulations of nicotine and flavorings, but the effects of specific e-liquid constituents and their concentrations on e-cig-induced autonomic imbalance and electrical dysfunction are unresolved. To that end, we tested the hypothesis that e-cigs modify cardiac autonomic balance and ventricular arrhythmogenesis in mice dependent on e-liquid constituent type and concentration. Methods. Using a crossover design and a serial exposure regimen, ECG-telemetered male C57BL/6J mice underwent whole-body exposure to e-cig aerosols generated from e-liquids containing different …


The Influence Of Temperature, Prey Availability, And Population Of Origin On Ectotherm Energetics, Allison R. Litmer 2023 University of Arkansas, Fayetteville

The Influence Of Temperature, Prey Availability, And Population Of Origin On Ectotherm Energetics, Allison R. Litmer

Graduate Theses and Dissertations

Climate change poses threats to organisms regarding direct and indirect effects of warming temperatures. Laboratory studies and predictive models are useful for understanding how temperature influences organisms, and the future of species’ life history and persistence. This dissertation expands upon current approaches to thermal studies and climate models, while investigating effects of warming nighttime temperature and altered prey availability on individuals and populations. Lizards in the genus Sceloporus were used as model organisms, as they are broadly distributed with thermally sensitive physiologies. The first dissertation chapter conducted meta-analyses to examine temperature-induced changes in food consumption, activity, and life history. Prominent …


Asparagine Restriction Enhances Cd8+ T Cell Metabolic Fitness And Antitumoral Functionality Through An Nrf2-Dependent Stress Response, J. N. Rashida Gnanaprakasam, Bhavana Kushwaha, Lingling Liu, Xuyong Chen, Siwen Kang, Tingting Wang, Teresa A. Cassel, Christopher M. Adams, Richard M. Higashi, David A. Scott, Gang Xin, Zihai Li, Jun Yang, Andrew N. Lane, Teresa Whei-Mei Fan, Ji Zhang, Ruoning Wang 2023 Nationwide Children’s Hospital

Asparagine Restriction Enhances Cd8+ T Cell Metabolic Fitness And Antitumoral Functionality Through An Nrf2-Dependent Stress Response, J. N. Rashida Gnanaprakasam, Bhavana Kushwaha, Lingling Liu, Xuyong Chen, Siwen Kang, Tingting Wang, Teresa A. Cassel, Christopher M. Adams, Richard M. Higashi, David A. Scott, Gang Xin, Zihai Li, Jun Yang, Andrew N. Lane, Teresa Whei-Mei Fan, Ji Zhang, Ruoning Wang

Markey Cancer Center Faculty Publications

Robust and effective T cell immune surveillance and cancer immunotherapy require proper allocation of metabolic resources to sustain energetically costly processes, including growth and cytokine production. Here, we show that asparagine (Asn) restriction on CD8+ T cells exerted opposing effects during activation (early phase) and differentiation (late phase) following T cell activation. Asn restriction suppressed activation and cell cycle entry in the early phase while rapidly engaging the nuclear factor erythroid 2-related factor 2 (NRF2)-dependent stress response, conferring robust proliferation and effector function on CD8+ T cells during differentiation. Mechanistically, NRF2 activation in CD8+ T cells conferred by Asn restriction …


Survey Of How Irregularities In The Electrical System Of The Human Heart Link To Different Heart Arrhythmias, Jazmine Boloor 2023 University of Nevada, Las Vegas

Survey Of How Irregularities In The Electrical System Of The Human Heart Link To Different Heart Arrhythmias, Jazmine Boloor

UNLV Theses, Dissertations, Professional Papers, and Capstones

This thesis explores the circuital pathway that a signal takes within the heart throughout a full heartbeat and provides a timing analysis. It then surveys the different pathways that could arise in the electrical system of the heart, and the associated heart diseases linked to the location of each pathway. Common heart arrhythmias such as atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia, atrial flutter, and atrial fibrillation are surveyed, and their pathways are analyzed. Electrocardiograms are presented to aid in understanding of the timing analysis associated with irregularity in heart function. Finally, this thesis explores an avenue of the heartbeat …


Evaluating The Influence Of Reciprocity Of Meeting Partner's Temperament Needs In Terms Of Marital Intimacy, Jimmie Scott Inman 2023 Liberty University

Evaluating The Influence Of Reciprocity Of Meeting Partner's Temperament Needs In Terms Of Marital Intimacy, Jimmie Scott Inman

Doctoral Dissertations and Projects

This narrative qualitative research project evaluated the influence of meeting a partner's needs regarding marital intimacy. This study investigated the archival data of couples who received temperament-focused marriage therapy. The essential principles taught throughout treatment (relational reciprocity, temperament needs met, the character of Christ) influence marital intimacy. A large body of work examined supports that needs-met (individual and relational) is essential for one's overall health and well-being. Three theories lay the theoretical foundation for this study: (1) Maslow's Hierarchy of Needs theory states that individuals have varying needs and that well-being hinges on their needs being met. (2) Schutz's Fundamental …


The Effects Of Ultra-Marathon Trail Running And The Physiological Response Of Stress On Salivary Biomarkers, Kevan W. Stout, Jeremy R. Pearson, Catherine A. Hambleton, Jake A. Deckert, Philip M. Gallagher 2023 University of Kansas

The Effects Of Ultra-Marathon Trail Running And The Physiological Response Of Stress On Salivary Biomarkers, Kevan W. Stout, Jeremy R. Pearson, Catherine A. Hambleton, Jake A. Deckert, Philip M. Gallagher

Journal of Human Performance in Extreme Environments

PURPOSE: This study investigated changes in salivary α-amylase (sAA), cortisol, and interleukin-1β (IL-1β) concentrations following completion of an ultra-marathon trail run (UMT) to better understand the physiological stressors imposed by this extreme type of race. METHODS: Eight subjects participated in this study. Each subject completed a 50 km UMT. Two-minute oral salivary swabs were taken 10 minutes prior to race start and again within 1 minute of race finish. Samples were analyzed for sAA, cortisol and IL-1β using ELISA kits. RESULTS: Our results demonstrated a significant increase in both sAA (p = 0.002) and cortisol (p < 0.001) from baseline. No significant differences were observed for IL-1β. There was no significant relationship between the observed sAA increase and race speed. The observed increase in cortisol was significantly correlated with race speed (R2 = 0.582, p …


Physical Profile Of Air Force Special Warfare Trainees, Kim A. Feeney, Bridget F. Melton, Helen W. Bland, Greg A. Ryan, Cody R. Butler 2023 Concordia University Chicago

Physical Profile Of Air Force Special Warfare Trainees, Kim A. Feeney, Bridget F. Melton, Helen W. Bland, Greg A. Ryan, Cody R. Butler

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 924-931, 2023. Physical fitness testing in the military is commonly used to assess whether service members are physically capable of performing the diverse physical tasks that may be required for their job. Body composition can influence an individual’s ability to physically perform. This study aimed to analyze the general physical profile of U.S. Air Force (USAF) special warfare candidates by assessing body composition results and physical assessment scores collected over the past four years. Male candidates (n = 1036) were 18.2 years to 39.5 years of age (M = 23.5, SD = …


Test-Retest Reliability Of A 4-Minute All-Out Critical Force Test In Rock Climbers, Zachary J. McClean, Keenan MacDougall, Jared R. Fletcher, Saied J. Aboodarda, Brian R. MacIntosh 2023 University of Calgary

Test-Retest Reliability Of A 4-Minute All-Out Critical Force Test In Rock Climbers, Zachary J. Mcclean, Keenan Macdougall, Jared R. Fletcher, Saied J. Aboodarda, Brian R. Macintosh

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 912-923, 2023. The purpose of this study was to assess the test-retest reliability of a 4-minute all-out critical force test in well-trained rock climbers. Thirteen rock climbers (n=4 females) completed a familiarization session and two all-out critical force tests on different days. During each trial, participants completed 24 repetitions of 7s right-handed, maximal effort hangs from a 20mm edge interspersed with 3 s rest. The end-test force (EF; i.e., critical force), impulse above EF (IEF), and peak force achieved durin g the test were analyzed with paired t-tests to determine differences between trials. Intraclass …


Psychophysical Load During The Multistage Marathon Des Sables: A Case Study, Leonidas G. Ioannou, Lydia Tsoutsoubi, Georgios I. Tsianos, Andreas D. Flouris 2023 FAME Laboratory, School of Physical Education and Sport Science, University of Thessaly, Greece

Psychophysical Load During The Multistage Marathon Des Sables: A Case Study, Leonidas G. Ioannou, Lydia Tsoutsoubi, Georgios I. Tsianos, Andreas D. Flouris

Journal of Human Performance in Extreme Environments

Introduction: This study investigated the impact of the multistage ultra-marathon event ‘‘Marathon des Sables’’ (MdS) performed in the Sahara Desert on the psychophysical capacity of an athlete. Methods: We collected and analyzed environmental, physiological, and behavioral data from a 39-year-old athlete who participated in the MdS. Specifically, we collected environmental temperature (Tenv), upper inguinal skin temperature (Tsk), heart rate, and running speed data. Also, we recorded blood glucose and lactate, thermal comfort, total body water, perceived exertion, and cognitive function at the start, middle, and the end of each race stage. Results: We found significant detrimental …


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