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Neither Thermosonication Nor Cold Sonication Is Better Than Pasteurization For Milk Shelf Life, Seung-Yong Lim, Lily C. Benner, Stephanie Clark 2019 Kunsan National University

Neither Thermosonication Nor Cold Sonication Is Better Than Pasteurization For Milk Shelf Life, Seung-Yong Lim, Lily C. Benner, Stephanie Clark

Food Science and Human Nutrition Publications

High-power, low-frequency ultrasound has been suggested as a novel processing technique with the potential to extend milk shelf life via inactivation of bacteria and spores that survive standard pasteurization. The primary objective of this research was to determine whether short-duration (≤60 s) sonication treatment, in conjunction with pasteurization, can increase shelf life while producing no adverse aroma effect. Skim milk was inoculated with Paenibacillus amylolyticus, a spore-forming, thermotolerant and psychrophilic milk contamination bacterium. Milk was sonicated under 6 selected amplitude and time conditions, except for control. Both cold sonicated (C-S) and thermosonicated (T-S) milk and milk treatments were pasteurized; however ...


Whole Egg Consumption Impairs Insulin Sensitivity In Rat Model Of Obesity And Type 2 Diabetes, Cassondra J. Saande, Megan A. Steffes, Joseph L. Webb, Rudy J. Valentine, Matthew J. Rowling, Kevin Schalinske 2019 Iowa State University

Whole Egg Consumption Impairs Insulin Sensitivity In Rat Model Of Obesity And Type 2 Diabetes, Cassondra J. Saande, Megan A. Steffes, Joseph L. Webb, Rudy J. Valentine, Matthew J. Rowling, Kevin Schalinske

Food Science and Human Nutrition Publications

Background: The literature regarding the relation between egg consumption and type 2 diabetes (T2D) is inconsistent and there is limited evidence pertaining to the impact of egg consumption on measures of insulin sensitivity. Objective: The objective of this study was to investigate the effect of dietary whole egg on metabolic biomarkers of insulin resistance in T2D rats. Downloaded from https://academic.oup.com/cdn/advance-article-abstract/doi/10.1093/cdn/nzz015/5374517 by Iowa State University user on 28 March 2019 Methods: Male Zucker diabetic fatty rats (n=12; 6 wk of age) and their lean controls (n=12; 6 wk ...


Cooking Frequency Associated With Dietary Quality In Icook-4h Youth Participants At Baseline, Amber D. Ford, Sarah E. Colby, Marissa McElrone, Lisa Franzen-Castle, Melissa D. Olfert, Kendra K. Kattelmann, Adrienne A. White 2019 University of Tennessee, Knoxville

Cooking Frequency Associated With Dietary Quality In Icook-4h Youth Participants At Baseline, Amber D. Ford, Sarah E. Colby, Marissa Mcelrone, Lisa Franzen-Castle, Melissa D. Olfert, Kendra K. Kattelmann, Adrienne A. White

Nutrition and Health Sciences -- Faculty Publications

Background: Increased intakes of ready-made and fast foods paralleled with decreased homemade food consumption have been associated with increased rates of obesity. Researchers have shown associations between cooking self-efficacy (SE) and cooking frequency (CF) with dietary quality and weight status. Some cooking interventions have shown positive associations with dietary outcomes, such as increased fruit and vegetable intake and decreased fast food consumption. There is still much unknown about SE and CF, especially among youth.

Objective: Determine baseline SE and CF and the associations with dietary quality and body mass index (BMI) of youth enrolled in iCook 4H.

Methods: Youth (n ...


Micrornas In Bovine Milk Exosomes Are Bioavailable In Humans But Do Not Elicit A Robust Pro-Inflammatory Cytokine Response, Ezra Mutai, Amanda E. Ramer-Tait, Janos Zempleni 2019 University of Nebraska-Lincoln

Micrornas In Bovine Milk Exosomes Are Bioavailable In Humans But Do Not Elicit A Robust Pro-Inflammatory Cytokine Response, Ezra Mutai, Amanda E. Ramer-Tait, Janos Zempleni

Nutrition and Health Sciences -- Faculty Publications

Background: Bovine milk exosomes are studied for their roles as bioactive food compounds and as vehicles for drug delivery. Both lines of investigation converge on immune function, e.g., immune regulation by absorption of microRNAs encapsulated in milk exosomes across species boundaries, and the possibility of exosomes and their cargos triggering an immune response if used in drug delivery. This study assessed the bioavailability of immune-related microRNAs from bovine milk and changes in plasma cytokine concentrations after milk consumption in humans, and the secretion of cytokines by human peripheral blood mononuclear cells (PBMCs) cultured with milk exosomes transfected with immune-relevant ...


Pyocyanin, A Virulence Factor Produced By Sepsis-Causing Pseudomonas Aeruginosa, Promotes Adipose Wasting And Cachexia, Nika Larian 2019 University of Kentucky

Pyocyanin, A Virulence Factor Produced By Sepsis-Causing Pseudomonas Aeruginosa, Promotes Adipose Wasting And Cachexia, Nika Larian

Theses and Dissertations--Pharmacology and Nutritional Sciences

Sepsis is a leading cause of death among critically ill patients that results in metabolic alterations including hypercatabolism, lipoatrophy, and muscle wasting, contributing to the development of cachexia. Septic cachexia is associated with loss of body weight, fat mass, and lean mass and dysregulated immune function. There are currently no efficacious treatment strategies for septic cachexia, and nutritional interventions have limited success in preventing hypercatabolic wasting. Pyocyanin is a virulence factor produced by sepsis-causing Pseudomonas aeruginosa that has been shown to activate the aryl hydrocarbon receptor (AhR), increase inflammation, and produce reactive oxygen species. Thus, pyocyanin represents a novel mechanistic ...


Forms Of Supplemental Selenium In Vitamin-Mineral Mixes Differentially Affect Serological And Hepatic Parameters Of Growing Beef Steers Grazing Endophyte-Infected Tall Fescue, Yang Jia 2019 University of Kentucky

Forms Of Supplemental Selenium In Vitamin-Mineral Mixes Differentially Affect Serological And Hepatic Parameters Of Growing Beef Steers Grazing Endophyte-Infected Tall Fescue, Yang Jia

Theses and Dissertations--Animal and Food Sciences

Consumption of endophyte-infected tall fescue results in a syndrome of negatively altered physiological systems, collectively known as fescue toxicosis. Another challenge to endophyte-infected tall fescue -based beef cattle operations is that the soils often are selenium (Se) poor, necessitating the need to provide supplemental Se. To test the general hypothesis that different forms of supplemental Se would ameliorate the negative effects of fescue toxicosis, predominately-Angus steers (BW = 183 ± 34 kg) were randomly selected from herds of fall-calving cows grazing an endophyte-infected tall fescue pasture and consuming vitamin-mineral mixes that contained 35 ppm Se as sodium selenite (ISe), SELPLEX (OSe), or ...


Apple Pomace As A Novel Aid For Western Diet-Induced Nonalcoholic Fatty Liver Disease In Young Female Sprague Dawley Rats, R. Chris Skinner 2019 West Virginia University

Apple Pomace As A Novel Aid For Western Diet-Induced Nonalcoholic Fatty Liver Disease In Young Female Sprague Dawley Rats, R. Chris Skinner

Graduate Theses, Dissertations, and Problem Reports

Apple pomace is a “waste” byproduct of apple processing that causes environmental pollution and is costly to dispose of. Yet, apple pomace is rich in dietary fibers and antioxidants. Analysis of apple pomace’s nutritional profile indicates suitability as a potential dietary treatment for non-alcoholic fatty liver disease (NAFLD) and the more severe non-alcoholic steatohepatitis (NASH). NAFLD is the most prevalent liver disease in the world with prevalence and severity expected to increase in both adults and children. Currently, there is no approved drug treatment for NAFLD and therefore, dietary intervention is the primary treatment. The study objectives were to ...


The Effects Of A Ketone Body On Synaptic Transmission, Alexandra Elizabeth Stanback 2019 University of Kentucky

The Effects Of A Ketone Body On Synaptic Transmission, Alexandra Elizabeth Stanback

Theses and Dissertations--Biology

The ketogenic diet is commonly used to control epilepsy, especially in cases when medications cannot. The diet typically consists of high fat, low carb, and adequate protein and produces a metabolite called acetoacetate. Seizure activity is characterized by glutamate excitotoxicity and therefore glutamate regulation is a point of research for control of these disorders. Acetoacetate is heavily implicated as the primary molecule responsible for decreasing glutamate in the synapse; it is believed that acetoacetate interferes with the transport of glutamate into the synaptic vesicles. The effects on synaptic transmission at glutamatergic synapses was studied in relation to the ketogenic diet ...


Evaluation Of A Brief Sodium Screener In Two Samples, Christy C. Tangney, Heather E. Rasmussen, Candace Richards, Michelle Li, Bradley M. Appelhans 2019 Rush University Medical Center

Evaluation Of A Brief Sodium Screener In Two Samples, Christy C. Tangney, Heather E. Rasmussen, Candace Richards, Michelle Li, Bradley M. Appelhans

Nutrition and Health Sciences -- Faculty Publications

The Sodium Screener© (SS©), as developed by NutritionQuest (Berkeley, CA, USA), was designed to reduce the burden of repeated dietary or urinary sodium measurements, but the accuracy of daily sodium intake estimates has not been reported. Associations were examined between sodium intakes derived from the SS© scores and repeated 24-h recalls (24DR) in two studies with different administration modes. In one study, 102 registered dietitians (RD) completed three Automated Self-Administered 24DRs (ASA24©), version 2014, followed by the SS©; both were self-administered and web-based. In the second sample, (the Study of Household Purchasing Patterns, Eating, and Recreation or SHoPPER), trained dietitians ...


State Population Influences Athletic Performance Combine Test Scores In High School-Aged American Football Players, Zachary M. Gillen, Marni E. Shoemaker, Brianna D. Mckay, Joel T. Cramer 2019 University of Nebraska - Lincoln

State Population Influences Athletic Performance Combine Test Scores In High School-Aged American Football Players, Zachary M. Gillen, Marni E. Shoemaker, Brianna D. Mckay, Joel T. Cramer

Nutrition and Health Sciences -- Faculty Publications

This study compared athletic performance differences among high school American football combine participants originating from states of different population sizes. High school-aged American football players (n=7,214) who had participated in athletic performance combines between March 2015 and January 2016 were included in this analysis. Data included combine date and location, school state of origin, football position, class, height, weight, 10-, 20-, and 40-yd dash times, pro-agility, L-cone drill, vertical jump, broad jump, and power push-up. Participants were separated into high- (state population>10,000,000; HIGH; n=2,804), mid- (state population=5,000,000-9,999,999; MID ...


Development And Validation Of The Vending Evaluation For Nutrient-Density (Vend)Ing Audit, Tanya M. Horacek, Elif Dede Yildirim, Melissa Matthews Schreiber, Carol Byrd-Bredbenner, Sarah E. Colby, Adrienne A. White, Karla P. Shelnutt, Melissa D. Olfert, Anne E. Matthews, Kristin Riggsbee, Lisa Franzen-Castle, Jesse Stabile Morrell, Kendra Kattelmann 2019 Syracuse University

Development And Validation Of The Vending Evaluation For Nutrient-Density (Vend)Ing Audit, Tanya M. Horacek, Elif Dede Yildirim, Melissa Matthews Schreiber, Carol Byrd-Bredbenner, Sarah E. Colby, Adrienne A. White, Karla P. Shelnutt, Melissa D. Olfert, Anne E. Matthews, Kristin Riggsbee, Lisa Franzen-Castle, Jesse Stabile Morrell, Kendra Kattelmann

Nutrition and Health Sciences -- Faculty Publications

Background: This paper describes the development and validation of the Vending Evaluation for Nutrient-Density (VEND)ing audit to comprehensively evaluate vended products based upon healthfulness, price and promotion, and machine accessibility. Methods: A novel vending nutrient-density score was created to determine the healthfulness of vended snack/beverage products. Field tested in United States colleges, VENDing audit (Σnutrient-density + 10 x % healthy products) and Support sub-scores (price + promotion + accessibility) were calculated for snack/beverage machines. Higher scores indicate more healthful vending options and supports for choosing healthfully. Nutrition Environment Measures Survey-Vending (NEMS-V) was used to validate the nutrient-density score for a sub-sample ...


Development And Validation Of The Policies, Opportunities, Initiatives And Notable Topics (Points) Audit For Campuses And Worksites, Tanya M. Horacek, Marlei Simon, Elif Dede Yildirim, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Stabile Morrell, Anne E. Matthews, Wenjun Zhou, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown 2019 Syracuse University

Development And Validation Of The Policies, Opportunities, Initiatives And Notable Topics (Points) Audit For Campuses And Worksites, Tanya M. Horacek, Marlei Simon, Elif Dede Yildirim, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Stabile Morrell, Anne E. Matthews, Wenjun Zhou, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown

Nutrition and Health Sciences -- Faculty Publications

Background: Workplace or campus wellness/obesity-prevention policies and initiatives can improve health. Research tools to assess worksite or campus policies/initiatives are scarce. Thus, the aim of this research is to develop and validate the policies, opportunities, initiatives, and notable topics (POINTS) audit. Methods: POINTS was developed and refined via expert review, pilot-testing, and field testing. Trained researchers completed a web-based review from a student-focus or employee-focus regarding 34 health-promoting topics for colleges. Each topic was evaluated on a 0–2 scale: 0 = no policy/initiative, 1 = initiatives, 2 = written policy. When a written policy was detected, additional policy support ...


The Validity Of The Emg And Mmg Techniques To Examine Muscle Hypertrophy, Ethan C. Hill, Terry J. Housh, Josh L. Keller, Cory M. Smith, Richard Schmidt, Glen O. Johnson 2019 University of Nebraska-Lincoln

The Validity Of The Emg And Mmg Techniques To Examine Muscle Hypertrophy, Ethan C. Hill, Terry J. Housh, Josh L. Keller, Cory M. Smith, Richard Schmidt, Glen O. Johnson

Nutrition and Health Sciences -- Faculty Publications

Objective: The purpose of this investigation was to examine the ability of the electromyographic (EMG) and mechanomyographic (MMG) amplitude versus torque relationships to track group and individual changes in muscle hypertrophy as a result of resistance training.

Approach: Twelve women performed four weeks of forearm flexion blood flow restriction (BFR) resistance training at a frequency of three times per week. The training was performed at an isokinetic velocity of 120°∙s1 with a training load that corresponded to 30% of concentric peak torque. Muscle hypertrophy was determined using ultrasound-based assessments of muscle cross-sectional area from the biceps brachii. Training-induced ...


Incorporating Technology Into The Icook 4-H Program, A Cooking Intervention For Adults And Children: Randomized Controlled Trial, Sarah Colby, Lauren Moret, Melissa D. Olfert, Kendra Kattelmann, Lisa Franzen-Castle, Kristin Riggsbee, Magen Payne, Ainsley Ellington, Cary Springer, Chelsea Allison, Sa'Nealdra Wiggins, Rochelle Butler, Douglas Mathews, Adrienne A. White 2019 University of Tennessee, Knoxville

Incorporating Technology Into The Icook 4-H Program, A Cooking Intervention For Adults And Children: Randomized Controlled Trial, Sarah Colby, Lauren Moret, Melissa D. Olfert, Kendra Kattelmann, Lisa Franzen-Castle, Kristin Riggsbee, Magen Payne, Ainsley Ellington, Cary Springer, Chelsea Allison, Sa'nealdra Wiggins, Rochelle Butler, Douglas Mathews, Adrienne A. White

Nutrition and Health Sciences -- Faculty Publications

Background: Families who cook, eat, and play together have been found to have more positive health outcomes. Interventions are needed that effectively increase these health-related behaviors. Technology is often incorporated in health-related interventions but is not always independently assessed.

Objective: The objective of this study was to describe challenges and facilitators to incorporating technology into the iCook 4-H intervention program.

Methods: Dyads (n=228) composed of children (mean 9.4, SD 0.7 years old) and an adult primary meal preparer (mean 39.0, SD 8 years) were randomly assigned to a control (n=77) or treatment group (n=151 ...


Urolithin A, A Gut Metabolite, Improves Insulin Sensitivity Through Augmentation Of Mitochondrial Function And Biogenesis, Ashley Mulcahy Toney, Rong Fan, Yibo Xian, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung 2019 University of Nebraska-Lincoln

Urolithin A, A Gut Metabolite, Improves Insulin Sensitivity Through Augmentation Of Mitochondrial Function And Biogenesis, Ashley Mulcahy Toney, Rong Fan, Yibo Xian, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Nutrition and Health Sciences -- Faculty Publications

Objective: Urolithin A (UroA) is a major metabolite of ellagic acid produced following microbial catabolism in the gut. Emerging evidence has suggested that UroA modulates energy metabolism in various cells. However, UroA’s physiological functions related to obesity and insulin resistance remain unclear. Methods: Male mice were intraperitoneally administrated either UroA or dimethyl sulfoxide (vehicle) along with a high-fat diet for 12 weeks. Insulin sensitivity was evaluated via glucose and insulin tolerance tests and acute insulin signaling. The effects of UroA on hepatic triglyceride accumulation, adipocyte size, mitochondrial DNA content, and proinflammatory gene expressions were determined. The impact of UroA ...


Milk-Derived Exosomes And Metabolic Regulation, Janos Zempleni, Sonal Sukreet, Fang Zhou, Di Wu, Ezra Mutai 2019 University of Nebraska - Lincoln

Milk-Derived Exosomes And Metabolic Regulation, Janos Zempleni, Sonal Sukreet, Fang Zhou, Di Wu, Ezra Mutai

Nutrition and Health Sciences -- Faculty Publications

Exosomes are natural nanoparticles that play an important role in cell-to-cell communication. Communication is achieved through the transfer of cargos, such as microRNAs, from donor to recipient cells and binding of exosomes to cell surface receptors. Exosomes and their cargos are also obtained from dietary sources, such as milk. Exosome and cell glycoproteins are crucial for intestinal uptake. A large fraction of milk exosomes accumulates in the brain, whereas the tissue distribution of microRNA cargos varies among distinct species of microRNA. The fraction of milk exosomes that escapes absorption elicits changes in microbial communities in the gut. Dietary depletion of ...


Using Ripple Effects Maps To Identify Story Threads: A Framework To Link Private To Public Value, Jane E. Haskell, Barbara A. Baker, Melissa D. Olfert, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Adrienne A. White 2019 University of Maine

Using Ripple Effects Maps To Identify Story Threads: A Framework To Link Private To Public Value, Jane E. Haskell, Barbara A. Baker, Melissa D. Olfert, Sarah E. Colby, Lisa Franzen-Castle, Kendra K. Kattelmann, Adrienne A. White

Nutrition and Health Sciences -- Faculty Publications

As funding opportunities are shifting and competitions for grant dollars increase, Extension programs need significant, measurable outcomes and impacts (Hachfeld, Bau, Holcomb, & Craig, 2013). Too often, program evaluation consists of data on inputs, activities, participants’ involvements, and feedback or changes in knowledge without providing evidence of changes in behavior and potential long-term social, economic, and environmental changes (Franz & Townson, 2008; Riggins, 2017; Stup, 2003).

The value of community programs must be expressed in captivating ways to garner public awareness and support (Franz, 2011; Franz, Arnold, & Baughman, 2014). Common

methodologies for expressing program value have included storytelling (Boyer et al., 2009; Franz, 2013), system-wide benchmarking (Archer et al., 2007), and impact indicators (Morse, French, & Chazdon, 2016). Determining value entails understanding and documenting what lies between the description of private benefit gained by the program participant and an expression of community benefit. Riggins (2017) emphasized that federal decision-makers must take this one step further by going from individual awareness and community-level outcomes to public value outcomes at a federal level.

The purpose of this article is to present a process that could be used to capture participant thoughts and communicate private value and public value of a health promotion program. Evaluation data generated from a 4-H obesity prevention program were used to identify story threads or storylines about linkages between private value and potential public value of the program. Ripple Effects Mapping (REM) incorporating the Community Capitals Framework (CCF; Emery, Fey, & Flora, 2006) was implemented as a qualitative evaluation of the evidence-based five-state study, iCook 4-H (White, Colby, Franzen-Castle, Kattelmann, & Olfert 2014), and data from Maine were used to detail the process.


The Effects Of Inulin And Galactooligosaccharides On The Production Of Reuterin By Lactobacillus Reuteri, Micah Dwight Forshee 2018 Olivet Nazarene University

The Effects Of Inulin And Galactooligosaccharides On The Production Of Reuterin By Lactobacillus Reuteri, Micah Dwight Forshee

ELAIA

The microbiome is a dynamic community that can positively and negatively influence host health. Lactobacillus reuteri is a probiotic that has received much attention for its ability to inhibit pathogens such as Salmonella typhimurium, Escherichia coli, and Clostridium difficile. It does so by its unique ability to metabolize glycerol into the antimicrobial compound 3-HPA, which is commonly referred to as reuterin. The ability to secrete reuterin is dependent not only on glycerol availability but also the concentration of glucose. In fact, there appears to be a “goldilocks” ratio between glucose and glycerol as either too much or too little glucose ...


Capture, Concentration And Detection Of Salmonella In Foods Using Magnetic Ionic Liquids And Recombinase Polymerase Amplification, Stephanie A. Hice, Kevin D. Clark, Jared L. Anderson, Byron F. Brehm-Stecher 2018 Iowa State University

Capture, Concentration And Detection Of Salmonella In Foods Using Magnetic Ionic Liquids And Recombinase Polymerase Amplification, Stephanie A. Hice, Kevin D. Clark, Jared L. Anderson, Byron F. Brehm-Stecher

Food Science and Human Nutrition Publications

We have previously investigated the extraction and concentration of bacteria from model systems using magnetic ionic liquid (MIL) solvents, while retaining their viability. Here, we combine MIL-based sample preparation with isothermal amplification and detection of Salmonella-specific DNA using Recombinase Polymerase Amplification (RPA). After initial developmental work with Serratia marcescens in water, Salmonella Typhimurium ATCC 14028 was inoculated in water, 2% milk, almond milk or liquid egg samples and extracted using one of two MILs, including: trihexyl(tetradecyl)phosphonium cobalt(II) hexafluoroacetylacetonate ([P66614+][Co(hfacac)3–]) and trihexyl(tetradecyl)phosphonium nickel(II) hexafluoroacetylacetonate ([P66614+][Ni(hfacac)3–]). Viable cells were ...


Combination Regimens Using Dietary Components For The Chemoprevention Of Colorectal Cancer And Inflammation, Christina DiMarco-Crook 2018 University of Massachusetts Amherst

Combination Regimens Using Dietary Components For The Chemoprevention Of Colorectal Cancer And Inflammation, Christina Dimarco-Crook

Doctoral Dissertations

ABSTRACT

COMBINATION REGIMENS USING DIETARY COMPONENTS FOR THE

CHEMOPREVENTION OF COLORECTAL CANCER

AND INFLAMMATION

September 2018

CHRISTINA DIMARCO-CROOK, B.S., IMMACULATA UNIVERSITY

M.S., DREXEL UNIVERSITY

Ph.D., UNIVERSITY OF MASSACHUSETTS AMHERST

Directed by: Professor Hang Xiao

Dietary components have been found to effectively modulate multiple deregulated signaling pathways associated with the initiation and progression of carcinogenesis and inflammation in cellular and animal models. However, clinical studies have shown mixed results when examining the efficacy of individual dietary components, perhaps suggestive of the synergism that exists between multiple components within a particular food and the diet as a whole. Additional ...


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