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Articles 1 - 30 of 541

Full-Text Articles in Molecular, Genetic, and Biochemical Nutrition

The Analysis Of Folate-Dependent Transcription Factor Zinc Finger Protein 410, Feifan Xu Apr 2021

The Analysis Of Folate-Dependent Transcription Factor Zinc Finger Protein 410, Feifan Xu

Senior Honors Theses

A previous study that introduced dietary folate to mice in the form of folic acid to determine if gene activity would be altered based on this biological molecule demonstrated that mice without folic acid had cognition deficits, and this phenomenon was correlated with altered gene expression in their brains. The included bioinformatic analysis revealed two main transcription factors that bind to proteins in the nucleus, and one is known as the Zinc Finger Protein 410 (Zfp410). Due to the lack of literature explaining the function of this transcription factor, this project is intended to analyze Zfp410 in detail from scratch ...


Covid-19 Contagion Among Communities With Limited English Proficiency: Lesson From Volunteerism, Falah N. Rashoka M.S Jan 2021

Covid-19 Contagion Among Communities With Limited English Proficiency: Lesson From Volunteerism, Falah N. Rashoka M.S

Nutrition and Health Sciences -- Faculty Publications

The COVID-19 affects all communities in the United States, but its impact differs from one community to another. Undoubtedly, the vulnerable populations are more impacted than others, especially refugees and immigrants. This study seeks to understand the impact of COVID-19 on marginalized communities and the need to communicate health-related information equally. A lesson learned from observation during an ongoing pandemic, including what I learned through my volunteer work between mid-March and August 2020. The study finds that neighbors with limited English Proficiency (LEP) and limited education could quickly transfer the COVID-19 virus to another neighbor with high income and well-educated ...


Differential Effects Of Whole Red Raspberry Polyphenols And Their Gut Metabolite Urolithin A On Neuroinflammation In Bv-2 Microglia, Ashley Mulcahy Toney, Mahaa Albusharif, Duncan Works, Luke Polenz, Stacie Schlange, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung Jan 2021

Differential Effects Of Whole Red Raspberry Polyphenols And Their Gut Metabolite Urolithin A On Neuroinflammation In Bv-2 Microglia, Ashley Mulcahy Toney, Mahaa Albusharif, Duncan Works, Luke Polenz, Stacie Schlange, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Nutrition and Health Sciences -- Faculty Publications

Whole red raspberry polyphenols (RRW), including ellagic acid, and their gut-derived metabolite, urolithin A (UroA), attenuate inflammation and confer health benefits. Although results from recent studies indicate that polyphenols and UroA also provide neuroprotective effects, these compounds differ in their bioavailability and may, therefore, have unique effects on limiting neuroinflammation. Accordingly, we aimed to compare the neuroprotective effects of RRW and UroA on BV-2 microglia under both 3 h and 12 and 24 h inflammatory conditions. In inflammation induced by lipopolysaccharide (LPS) and ATP stimulation after 3 h, RRW and UroA suppressed pro- inflammatory cytokine gene expression and regulated the ...


Anti-Inflammatory Properties Of Blackberry Phenolic And Volatile Compounds, Pauline Morin Dec 2020

Anti-Inflammatory Properties Of Blackberry Phenolic And Volatile Compounds, Pauline Morin

Theses and Dissertations

Berries are known for many health benefits including anti-inflammatory properties that lower risks of chronic diseases. These properties have been linked to high concentrations of phenolic compounds, especially anthocyanins. However, the present study hypothesized that volatiles could contribute to the berries’ bioactive properties. Thus, the objectives of this research are to profile the phenolic and volatile composition of 16 blackberry genotypes harvested at the Fruit Research Center of the University of Arkansas and to evaluate the antiinflammatory capacities of three selected genotypes on inflamed cells. Phenolic and volatile profiles were evaluated using chromatographic techniques. The three genotypes A2528T, A2587T and ...


Antioxidant Properties And Anti-Cancer Effects Of Polyphenols In Sweetpotato Leaves, Josue Bolanos Dec 2020

Antioxidant Properties And Anti-Cancer Effects Of Polyphenols In Sweetpotato Leaves, Josue Bolanos

Theses and Dissertations

Although the root is widely consumed, sweetpotato leaves (SPL) are often discarded and are only consumed in a few countries. In the United States, SPL consumption is limited to private gardens, particularly in the Southeastern United States. Not only are SPL a good source of nutrients such as vitamins and minerals, but they also contain polyphenol compounds including the caffeoylquinic acid derivatives and carotenoids such as lutein. Several studies have shown the polyphenol contents and antioxidant capacities of SPL, which vary based on year and variety, while few studies have shown anti-colon cancer effects of SPL. Therefore, this study investigated ...


Non-Coding Rna In Raw And Commercially Processed Milk And Putative Targets Related To Growth And Immune-Response, Sayane Shome, Robert Jernigan, Donald C. Beitz, Stephanie Clark, E. Testroet Dec 2020

Non-Coding Rna In Raw And Commercially Processed Milk And Putative Targets Related To Growth And Immune-Response, Sayane Shome, Robert Jernigan, Donald C. Beitz, Stephanie Clark, E. Testroet

Food Science and Human Nutrition Publications

Background: Bovine milk contains extracellular vesicles (EVs) that play a role in cellular communication, acting in either an autocrine, paracrine, or an exocrine manner. The unique properties of the EVs protect the cargo against degradation. We proled the ncRNAs (non-coding RNA) present in the EVs from ve uid dairy products - raw whole milk, heat-treated skim milk, homogenized heat-treated skim milk, pasteurized homogenized skim milk, and pasteurized heavy whipping cream (four replicates each) obtained at different processing steps from a commercial dairy plant. EVs and their cargo were extracted by using a validated commercial kit that has been shown to be ...


The Effect Of Epa And Dha On Skeletal Muscle Physiology And Energy Balance, Saeed Jebor Ghnaimawi Dec 2020

The Effect Of Epa And Dha On Skeletal Muscle Physiology And Energy Balance, Saeed Jebor Ghnaimawi

Theses and Dissertations

Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) supplementation commonly suggested during pregnancy confers many health benefits on offspring and more recently improves fetal BAT development and induces myoblast trans-differentiation into adiopocytes through activating PPARs expression. Embryonic myoblast is a highly flexible cell showing great capacity to change its phenotype into adipocyte in response to EPA and DHA supplementation in many in vitro models. However, a little is known about the identity of derived adipocytes, whether, they change into brown or white adipocyte, and in vivo evidence is still missing. Given that the myogeneis process is initiated at the mid of ...


The Energy Savings-Oxidative Cost Trade-Off For Migratory Birds During Endurance Flight, Scott R. Mcwilliams, Barbara J. Pierce, Andrea Wittenzellner, Lillie A. Langlois, Sophia Engel, John R. Speakman, Olivia Fatica, Kristen J. Demoranville, Wolfgang Goymann, Lisa Trost, Amadeusz Bryla, Maciej Dzialo, Edyta T. Sadowska, Ulf Bauchinger Dec 2020

The Energy Savings-Oxidative Cost Trade-Off For Migratory Birds During Endurance Flight, Scott R. Mcwilliams, Barbara J. Pierce, Andrea Wittenzellner, Lillie A. Langlois, Sophia Engel, John R. Speakman, Olivia Fatica, Kristen J. Demoranville, Wolfgang Goymann, Lisa Trost, Amadeusz Bryla, Maciej Dzialo, Edyta T. Sadowska, Ulf Bauchinger

Biology Faculty Publications

Elite human and animal athletes must acquire the fuels necessary for extreme feats, but also contend with the oxidative damage associated with peak metabolic performance. Here, we show that a migratory bird with fuel stores composed of more omega-6 polyunsaturated fats (PUFA) expended 11% less energy during long-duration (6 hr) flights with no change in oxidative costs; however, this short-term energy savings came at the long-term cost of higher oxidative damage in the omega-6 PUFA-fed birds. Given that fatty acids are primary fuels, key signaling molecules, the building blocks of cell membranes, and that oxidative damage has long-term consequences for ...


Bifidobacterium Infantis Metabolizes 2'Fucosyllactose-Derived And Free Fucose Through A Common Catabolic Pathway Resulting In 1,2-Propanediol Secretion, Liv R. Dedon, Ezgi Ozcan, Asha Rani, David A. Sela Nov 2020

Bifidobacterium Infantis Metabolizes 2'Fucosyllactose-Derived And Free Fucose Through A Common Catabolic Pathway Resulting In 1,2-Propanediol Secretion, Liv R. Dedon, Ezgi Ozcan, Asha Rani, David A. Sela

Open Access Publications by UMMS Authors

Human milk oligosaccharides (HMOs) enrich beneficial bifidobacteria in the infant gut microbiome which produce molecules that impact development and physiology. 2'fucosyllactose (2'FL) is a highly abundant fucosylated HMO which is utilized by Bifidobacterium longum subsp. infantis, despite limited scientific understanding of the underlying mechanism. Moreover, there is not a current consensus on whether free fucose could be metabolized when not incorporated in a larger oligosaccharide structure. Based on metabolic and genomic analyses, we hypothesize that B. infantis catabolizes both free fucose and fucosyl oligosaccharide residues to produce 1,2-propanediol (1,2-PD). Accordingly, systems-level approaches including transcriptomics and proteomics ...


Whole Egg Consumption Increases Gene Expression Within The Glutathione Pathway In The Liver Of Zucker Diabetic Fatty Rats, Joe L. Webb, Amanda E. Bries, Brooke Vogel, Claudia Carrillo, Lily Harvison, Timothy A. Day, Michael J. Kimber, Rudy J. Valentine, Matthew J. Rowling, Stephanie Clark, Elizabeth M. Mcniell, Kevin L. Schalinske Nov 2020

Whole Egg Consumption Increases Gene Expression Within The Glutathione Pathway In The Liver Of Zucker Diabetic Fatty Rats, Joe L. Webb, Amanda E. Bries, Brooke Vogel, Claudia Carrillo, Lily Harvison, Timothy A. Day, Michael J. Kimber, Rudy J. Valentine, Matthew J. Rowling, Stephanie Clark, Elizabeth M. Mcniell, Kevin L. Schalinske

Food Science and Human Nutrition Publications

Nutrigenomic evidence supports the idea that Type 2 Diabetes Mellitus (T2DM) arises due to the interactions between the transcriptome, individual genetic profiles, lifestyle, and diet. Since eggs are a nutrient dense food containing bioactive ingredients that modify gene expression, our goal was to examine the role of whole egg consumption on the transcriptome during T2DM. We analyzed whether whole egg consumption in Zucker Diabetic Fatty (ZDF) rats alters microRNA and mRNA expression across the adipose, liver, kidney, and prefrontal cortex tissue. Male ZDF (fa/fa) rats (n = 12) and their lean controls (fa/+) (n = 12) were obtained at 6 wk ...


Thioredoxin Interacting Protein Is Required For A Chronic Energy-Rich Diet To Promote Intestinal Fructose Absorption, Anu Shah, Sezin Dagdeviren, Jordan P. Lewandowski, Angela B. Schmider, Elisabeth M. Ricci-Blair, Niranjana Natarajan, Henna Hundal, Hye Lim Noh, Randall H. Friedline, Charles Vidoudez, Jason K. Kim, Amy J. Wagers, Roy J. Soberman, Richard T. Lee Sep 2020

Thioredoxin Interacting Protein Is Required For A Chronic Energy-Rich Diet To Promote Intestinal Fructose Absorption, Anu Shah, Sezin Dagdeviren, Jordan P. Lewandowski, Angela B. Schmider, Elisabeth M. Ricci-Blair, Niranjana Natarajan, Henna Hundal, Hye Lim Noh, Randall H. Friedline, Charles Vidoudez, Jason K. Kim, Amy J. Wagers, Roy J. Soberman, Richard T. Lee

Open Access Publications by UMMS Authors

Increased consumption of fats and added sugars has been associated with an increase in metabolic syndromes. Here we show that mice chronically fed an energy-rich diet (ERD) with high fat and moderate sucrose have enhanced the absorption of a gastrointestinal fructose load, and this required expression of the arrestin domain protein Txnip in the intestinal epithelial cells. ERD feeding induced gene and protein expression of Glut5, and this required the expression of Txnip. Furthermore, Txnip interacted with Rab11a, a small GTPase that facilitates the apical localization of Glut5. We also demonstrate that ERD promoted Txnip/Glut5 complexes in the apical ...


Development Of Valuable And Functional Protein-Based Food Ingredients From Invasive Green Crabs, Bouhee Kang Aug 2020

Development Of Valuable And Functional Protein-Based Food Ingredients From Invasive Green Crabs, Bouhee Kang

Electronic Theses and Dissertations

European green crabs (Carcinus maenas L.) are an invasive species unintentionally introduced from Europe to the U.S. Their predation and burrowing activities have had detrimental effects on our marine habitats, aquaculture, and commercially important fisheries. Despite the large population of green crabs, they are not commercially utilized in North America as food products. The specific objectives of my research were to: 1) determine functional properties of protein recovered from green crab by isoelectric solubilization and precipitation (ISP) for potential food application, 2) investigate the application of enzymatic hydrolysis for deriving bioactive compounds from green crab proteins and examine the ...


Metabolomic Profiling Reveals Distinct And Mutual Effects Of Diet And Inflammation In Shaping Systemic Metabolism In Ldlr(-/-) Mice, Mario A. Lauterbach, Eicke Latz, Anette Christ Aug 2020

Metabolomic Profiling Reveals Distinct And Mutual Effects Of Diet And Inflammation In Shaping Systemic Metabolism In Ldlr(-/-) Mice, Mario A. Lauterbach, Eicke Latz, Anette Christ

Open Access Publications by UMMS Authors

Changes in modern dietary habits such as consumption of Western-type diets affect physiology on several levels, including metabolism and inflammation. It is currently unclear whether changes in systemic metabolism due to dietary interventions are long-lasting and affect acute inflammatory processes. Here, we investigated how high-fat diet (HFD) feeding altered systemic metabolism and the metabolomic response to inflammatory stimuli. We conducted metabolomic profiling of sera collected from Ldlr(-/-) mice on either regular chow diet (CD) or HFD, and after an additional low-dose lipopolysaccharide (LPS) challenge. HFD feeding, as well as LPS treatment, elicited pronounced metabolic changes. HFD qualitatively altered the systemic ...


Serum Vitamin B12 And Related 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase And Cubilin Genotypes Predict Neural Outcomes Across The AlzheimerʼS Disease Spectrum, K. E. Mcliman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette Jul 2020

Serum Vitamin B12 And Related 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase And Cubilin Genotypes Predict Neural Outcomes Across The AlzheimerʼS Disease Spectrum, K. E. Mcliman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette

Biomedical Sciences Publications

Epidemiological studies show mixed findings for serum vitamin B12 and both cognitive and regional volume outcomes. No studies to date have comprehensively examined, in non-supplemented individuals, serum B12 level associations with neurodegeneration, hypometabolism, and cognition across the Alzheimer's disease (AD) spectrum. Serum vitamin B12 was assayed from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL). Voxel-wise analyses regressed B12 levels against regional gray matter (GM) volume and glucose metabolism (p


Effects Of Broccoli And Carrots On Fecal Microrna Expression In Infants: A Short-Term Feeding Study, Kaleigh E. Beane Jul 2020

Effects Of Broccoli And Carrots On Fecal Microrna Expression In Infants: A Short-Term Feeding Study, Kaleigh E. Beane

Theses and Dissertations

Diets, through multiple mechanisms, cause significant impact on human health and disease etiology; proposed modes of action include modulation of non-coding RNAs and influences on the gut microbiome. Specifically, phytochemicals change human miRNA expression thereby impacting gut microbiome and/or increasing host immune functions. Apiaceous and cruciferous vegetables have been linked to decreased chronic inflammation, which is closely related with the host immune system, yet it is not investigated how these two classes of vegetables influence the colonic miRNA profile. In this study, therefore we aimed to determine the effects of short-term feeding of broccoli and carrot to infants on ...


Training Interns In Nutrition And Dietetics: Barriers And Motivators To Being A Preceptor, Andrea Hutchins, Jinette Fellows, Donna M. Winham May 2020

Training Interns In Nutrition And Dietetics: Barriers And Motivators To Being A Preceptor, Andrea Hutchins, Jinette Fellows, Donna M. Winham

Food Science and Human Nutrition Publications

Objectives Identify the perceptions and attitudes associated with the preceptor role and incentives that might encourage precepting among nutrition and dietetics professionals in the United States.

Methods A random sample of RDN and NDTR professionals from the Commission on Dietetic Registration credentialed practitioner database were invited to complete an online survey about knowledge, attitudes, and perceptions of the preceptor role. The survey was adapted from previous published instruments and validated via external content review, pretesting and post-test evaluation with pilot respondents.

Results A total of 311 of 2464 invited eligible participants completed the survey, yielding a response rate of 12 ...


The Representation Of Food-Related Environments In Virtual Reality, James Hollis, Shelley E. Woodall May 2020

The Representation Of Food-Related Environments In Virtual Reality, James Hollis, Shelley E. Woodall

Food Science and Human Nutrition Publications

Objectives: Virtual reality (VR) potentially provides an innovative tool for nutrition education/counselling. The objective of this study was to determine the a) sense of ‘presence’ (the feeling of being in a scene) experienced in two food related VR scenes b) capture information regarding the participants experiences in VR.


Optimization Of Dna Extraction From Human Milk, Cassandra Z. Rutherford May 2020

Optimization Of Dna Extraction From Human Milk, Cassandra Z. Rutherford

Graduate Theses

Background: Techniques are emerging for determining the best and most cost-effective way to test for human milk adulteration. Currently, the literature is focused on the use of qPCR testing, a technique used to isolate and amplify pieces of DNA for analysis. However, no recommendation currently exists on the best DNA extraction kit to use to achieve optimal DNA yield or purity from human milk samples for downstream qPCR use. Thus, the objective of this study is to assess and compare two DNA extraction kits for use with human milk samples for future DNA-based analysis in the testing for bovine milk ...


Liver Transcriptomic Analysis After Short- And Long-Term Feeding Of Soy Protein Isolate And Its Ability To Reduce Liver Steatosis In Obese Zucker Rats, Melisa Kozaczek May 2020

Liver Transcriptomic Analysis After Short- And Long-Term Feeding Of Soy Protein Isolate And Its Ability To Reduce Liver Steatosis In Obese Zucker Rats, Melisa Kozaczek

Theses and Dissertations

According to the Centers for Disease Control and Prevention (CDC) the prevalence of obesity in adults in the United States during 2017-2018 was a 42.4%, a high number considering all the risks factors associated with this disorder, such as cardiovascular disease, insulin resistance, diabetes type 2, and fatty liver disease, among others. Fatty liver disease is the accumulation of lipids in the liver that can account for more than 5 to 10% of the liver’s weight. There are two types of fatty liver disease, alcoholic fatty liver disease (AFLD), and non-alcoholic fatty liver disease (NAFLD). AFLD is the ...


Nutritional Supplementation And Skeletal Muscle Health In Chronic Diseases, Hexirui Wu May 2020

Nutritional Supplementation And Skeletal Muscle Health In Chronic Diseases, Hexirui Wu

Theses and Dissertations

Prevalence of chronic diseases in the United States keeps increasing in recent years. There are approximately four in ten adults having chronic diseases in America. Chronic diseases include obesity, aging, heart diseases, cancer and many others. This thesis mainly focuses on obesity and aging. Skeletal muscle performance is impaired in obesity and aging conditions. One common reason causing this could be higher fat mass and lower muscle mass. However, there is no study showing what pathways are involved in the imbalance of body composition. Therefore, the first objective of the thesis is to determine gene expression of selected pathways in ...


The Effects Of Retinoic Acid And Insulin On Glycogenesis In Hl1c Hepatoma Cells, Addison J. Bond, Guoxun Chen Dr. May 2020

The Effects Of Retinoic Acid And Insulin On Glycogenesis In Hl1c Hepatoma Cells, Addison J. Bond, Guoxun Chen Dr.

Chancellor’s Honors Program Projects

No abstract provided.


The Effects Of Skeletal Muscle Specific Cpt1b Knock Out On Genetically Obese Ay Mice, Allison Stone Apr 2020

The Effects Of Skeletal Muscle Specific Cpt1b Knock Out On Genetically Obese Ay Mice, Allison Stone

LSU Master's Theses

Fatty acid oxidation inhibition is one approach to reducing blood glucose levels in type II diabetes. Skeletal muscle specific Carnitine Palmitoyltransferase 1b knockout mice (Cpt1bm-/-) cannot transport long-chain fatty acids into the mitochondria to be oxidized in order to produce energy. Cpt1bm-/- mice have debilitated fat oxidation, less fat mass and improved glucose utilization compared to control C57BL/6 mice fed a 25% fat diet.

We hypothesized that CPT1b inhibition could reduce fat mass and lower blood glucose levels in a genetic mouse model of obesity and diabetes. To test this, we bred Cpt1bm-/- mice to A ...


Are Dietary Fish Oil Supplements Appropriate For Dyslipidemia Management? A Review Of The Evidence, Samuel C. R. Sherratt, Michael Lero, R. Preston Mason Apr 2020

Are Dietary Fish Oil Supplements Appropriate For Dyslipidemia Management? A Review Of The Evidence, Samuel C. R. Sherratt, Michael Lero, R. Preston Mason

Open Access Publications by UMMS Authors

PURPOSE OF REVIEW: The purpose of this review is to assess whether dietary fish oil supplements can be appropriate for patients with elevated triglycerides and cardiovascular risk based on a comprehensive analysis of their composition, and level of regulatory oversight.

RECENT FINDINGS: Approximately 19 million people in the United States take fish oil supplements, many for the purpose of treating or preventing heart disease. Unlike prescription products, fish oil supplements are classified as food by the Food and Drug Administration (FDA) and are not required to undergo manufacturing oversight or clinical testing. Analysis of widely used dietary fish oil supplements ...


A Syringe-Based Biosensor To Rapidly Detect Low Levels Of Escherichia Coli (Ecor13) In Drinking Water Using Engineered Bacteriophages, Troy C. Hinkley, Spencer Garing, Paras Jain, John Williford, Anne-Laure M. Le Ny, Kevin P. Nichols, Joseph E. Peters, Joey N. Talbert, Sam R. Nugen Mar 2020

A Syringe-Based Biosensor To Rapidly Detect Low Levels Of Escherichia Coli (Ecor13) In Drinking Water Using Engineered Bacteriophages, Troy C. Hinkley, Spencer Garing, Paras Jain, John Williford, Anne-Laure M. Le Ny, Kevin P. Nichols, Joseph E. Peters, Joey N. Talbert, Sam R. Nugen

Food Science and Human Nutrition Publications

A sanitized drinking water supply is an unconditional requirement for public health and the overall prosperity of humanity. Potential microbial and chemical contaminants of drinking water have been identified by a joint effort between the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF), who together establish guidelines that define, in part, that the presence of Escherichia coli (E. coli) in drinking water is an indication of inadequate sanitation and a significant health risk. As E. coli is a nearly ubiquitous resident of mammalian gastrointestinal tracts, no detectable counts in 100 mL of drinking water is the ...


Rs Content And Egi Value Of Cooked Noodles (I): Effect Of Cooking Methods, Yu Tian, Ming Li, Aoxing Tang, Jay-Lin Jane, Sushil Dhital, Boli Guo Mar 2020

Rs Content And Egi Value Of Cooked Noodles (I): Effect Of Cooking Methods, Yu Tian, Ming Li, Aoxing Tang, Jay-Lin Jane, Sushil Dhital, Boli Guo

Food Science and Human Nutrition Publications

Noodles are widely consumed in China, which can be cooked in different ways. The effects of different cooking methods (boiling, steaming, microwave heating, stir-frying and frying) on the resistance starch (RS) content and digestive properties (digestion rate, digestibility and estimated glycemic index (eGI) value) of noodles were investigated. The RS content was greatly affected by the cooking time, and it was varied when the noodles were optimally cooked using different cooking methods. The RS contents of the microwaved and stir-fried noodles were relatively high (0.59%–0.99%), but it was lower (0.43%–0.44%) in the boiled and ...


Pinto Beans And Green Beans Result In Comparable Glycemic Control In Adults With Type 2 Diabetes: A Randomized Pilot Trial, Andrea Hutchins, Donna M. Winham Mar 2020

Pinto Beans And Green Beans Result In Comparable Glycemic Control In Adults With Type 2 Diabetes: A Randomized Pilot Trial, Andrea Hutchins, Donna M. Winham

Food Science and Human Nutrition Publications

Aims: Glucose control is essential to slow disease progression in people with type 2 diabetes mellitus (T2DM). The acute effects of dry bean consumption on glucose control are well established, but their long-term effects in daily diets are less known.

Methods: The effect of daily consumption of ½ cup pinto beans, compared to ½ cup green beans, on fasting glucose, postprandial glucose and hemoglobin A1c (HbA1c) in adults with T2DM was examined. After a 2-week wash-in period, 13 participants were randomized to two 12-week long treatments: pinto beans and green beans. Before and after each intervention period, a fasted venous ...


Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu Feb 2020

Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu

Nutrition and Health Sciences -- Faculty Publications

Fulminant hepatic failure (FHF) is a rare, life-threatening liver disease with a poor prognosis. Administration of D-galactosamine (GalN) and lipopolysaccharide (LPS) triggers acute liver injury in mice, simulating many clinical features of FHF in humans; therefore, this disease model is often used to investigate potential therapeutic interventions to treat FHF. Recently, suppression of the nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome, was shown to alleviate the severity of GalN/LPS-induced liver damage in mice. Therefore, the goal of this study was to find dietary exosome-like nanoparticles (ELNs) with therapeutic potential in curbing FHF ...


Magnetic Ionic Liquids: Interactions With Bacterial Cells, Behavior In Aqueous Suspension, And Broader Applications, Stephanie A. Hice, Marcelino Varona, Allison R. Brost, Fan Dai, Jared L. Anderson, Byron F. Brehm-Stecher Feb 2020

Magnetic Ionic Liquids: Interactions With Bacterial Cells, Behavior In Aqueous Suspension, And Broader Applications, Stephanie A. Hice, Marcelino Varona, Allison R. Brost, Fan Dai, Jared L. Anderson, Byron F. Brehm-Stecher

Food Science and Human Nutrition Publications

Previously, we demonstrated capture and concentration of Salmonella enterica subspecies enterica ser. Typhimurium using magnetic ionic liquids (MILs), followed by rapid isothermal detection of captured cells via recombinase polymerase amplification (RPA). Here, we report work intended to explore the broader potential of MILs as novel pre-analytical capture reagents in food safety and related applications. Specifically, we evaluated the capacity of the ([P66614+][Ni(hfacac)3−]) (“Ni(II)”) MIL to bind a wider range of human pathogens using a panel of Salmonella and Escherichia coli O157:H7 isolates, including a “deep rough” strain of S. Minnesota. We extended this exploration further ...


Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso Feb 2020

Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso

Nutrition and Health Sciences -- Faculty Publications

Background: Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure populations. The RUSF formulations have been further modified to add micronutrients including iron and folic acid needed during pregnancy and lactation. Because docosahexaenoic acid (DHA, C22:6 n-3) enhances fetal development and birth outcomes, it has been suggested that perhaps RUSF formulations for pregnancy should also include this Omega 3 fatty acid. The goal of the present study was to gain an understanding of Zambian women’s knowledge of nutritional needs in pregnancy through structured ...


Food Behaviors, Health, And Bean Nutrition Awareness Among Low-Income Men: A Pilot Study, Michelle M. Heer, Donna M. Winham Feb 2020

Food Behaviors, Health, And Bean Nutrition Awareness Among Low-Income Men: A Pilot Study, Michelle M. Heer, Donna M. Winham

Food Science and Human Nutrition Publications

Bean consumption is known to lower blood cholesterol and postprandial blood glucose. With higher chronic disease risk, low-income men could theoretically benefit from increased bean intakes. The study objective was to explore low-income men’s food behaviors, bean health benefit awareness, and bean consumption practices and preferences. Seventy-one low-income men aged 18–65 years (µ 41 ± 12.7; 53% white, 16% black, 31% Hispanic) completed a survey on health risks, food behaviors, bean health knowledge, attitudes toward dry and canned beans, and bean preferences. Eighty-seven percent had one or more health risk factors of physical inactivity, smoking, or obesity. Most ...