Life Stressors And Immune Aging: Protective Effects Of Cognitive Reappraisal,
2023
University of Pittsburgh
Life Stressors And Immune Aging: Protective Effects Of Cognitive Reappraisal, Rebecca G. Reed, Steven R. Presnell, Ahmad Al-Attar, Charles T. Lutz, Suzanne C. Segerstrom
Markey Cancer Center Faculty Publications
Stressful life events may accelerate aspects of immune aging, but habitual use of an adaptive emotion regulation strategy, cognitive reappraisal, may attenuate these effects. This study examined whether cognitive reappraisal moderates the associations between life stressor frequency and stressor desirability on aspects of immune aging, including late-differentiated CD8+ T and natural killer (NK) cells and inflammatory markers (IL-6, TNF-α, and CRP), both between and within people in a longitudinal sample of 149 older adults (mean age = 77.8, range: 64–92 years). Participants reported stressful life events, use of cognitive reappraisal, and provided blood semiannually for up to 5 years to …
The Reinforcement Enhancing Effects Of Delta-9-Tetrahyrdrocannabinol (Thc) In Male And Female Rats,
2023
East Tennessee State University
The Reinforcement Enhancing Effects Of Delta-9-Tetrahyrdrocannabinol (Thc) In Male And Female Rats, Kynah Walston
Electronic Theses and Dissertations
Cannabis is widely consumed by humans for pharmacological effects that are mediated by THC, though there is little evidence that THC is a primary reinforcer in non-human animal models. We hypothesized that THC may have potent reinforcement enhancing effects, comparable to other drugs (e.g., nicotine and caffeine) which are also widely consumed by humans, but difficult to establish as primary reinforcers in non-humans. In three experiments with male and female rats saccharin (SACC) or a visual stimulus (VS) served as reinforcers for operant behavior. We explored several pharmacological parameters of THC on responding for SACC or VS, including THC dose, …
The Mind Behind The Buy: Exploring The World Of Neuromarketing,
2023
Kenyon College
The Mind Behind The Buy: Exploring The World Of Neuromarketing, Gabriela Cruz Echeverria
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
(Maybe Not) All Of The Lights,
2023
Kenyon College
(Maybe Not) All Of The Lights, Babiker Higazi
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Scientific Kenyon: Neuroscience Edition (Full Issue),
2023
Kenyon College
Scientific Kenyon: Neuroscience Edition (Full Issue)
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Did: Is It Trauma Or Just Fantasy?,
2023
Kenyon College
Did: Is It Trauma Or Just Fantasy?, Sebastian Geeze
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Man's Best Friend Finally Talks Back: Bunny The "Talking" Dog,
2023
Kenyon College
Man's Best Friend Finally Talks Back: Bunny The "Talking" Dog, Maeve Griffin
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
A Brief History Of Psychedelia: From Ancient Rituals To Modern Medicine,
2023
Kenyon College
A Brief History Of Psychedelia: From Ancient Rituals To Modern Medicine, Vikas Gudhe
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Memory Comes In Waves: How Sharp-Wave Ripple Dynamics Are Disrupted By Sleep Deprivation,
2023
Kenyon College
Memory Comes In Waves: How Sharp-Wave Ripple Dynamics Are Disrupted By Sleep Deprivation, Maximos Mccune
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Neurodegeneration: You Have More Influence Than You Might Think,
2023
Kenyon College
Neurodegeneration: You Have More Influence Than You Might Think, Ben Shropshire
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Building A Better Athlete: How Great Coaches Game The Nervous System For Optimal Performance,
2023
Kenyon College
Building A Better Athlete: How Great Coaches Game The Nervous System For Optimal Performance, Mark Lang
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Binaural Beats: Good Or Goop?,
2023
Kenyon College
Binaural Beats: Good Or Goop?, Sari Wagner
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Dispelling Depression Dogma: Why Depression Is More Than A Chemical Imbalance,
2023
Kenyon College
Dispelling Depression Dogma: Why Depression Is More Than A Chemical Imbalance, Jorge Roman
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
"Your Love Is My Drug" - Kesha,
2023
Kenyon College
"Your Love Is My Drug" - Kesha, Olivia Smith
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
P120-Catenin Subfamily Members Have Distinct As Well As Shared Effects On Dendrite Morphology During Neuron Development In Vitro,
2023
The Texas Medical Center Library
P120-Catenin Subfamily Members Have Distinct As Well As Shared Effects On Dendrite Morphology During Neuron Development In Vitro, Maxsam Donta
Dissertations and Theses (Open Access)
Proper dendrite morphology is essential for neuronal connectivity and function, and abnormal dendrite morphology is seen in many neurological pathologies. This study characterizes and compares the effects of a group of four proteins – the p120-catenin subfamily – that regulate cytoskeletal remodeling and dendrite morphology. To do this, I tracked the endogenous localization of each p120-subfamily catenin during neuron development, and I determined how altering the expression of each p120-subfamily catenin affects dendrite morphology. I find that all catenins are expressed in dendritic processes and the soma, ARVCF-catenin is expressed at relatively high proportions in the nucleus, and p120-catenin and …
Effects Of Acute And Repeated Alcohol Exposure On Expression Of Synaptic-Associated Genes In The Male And Female Mouse Mpfc,
2023
Binghamton University--SUNY
Effects Of Acute And Repeated Alcohol Exposure On Expression Of Synaptic-Associated Genes In The Male And Female Mouse Mpfc, Dhruba Podder
Undergraduate Honors Theses
Alcohol use disorder (AUD) is a serious chronic brain disease; in 2021 there were ~29.5 million people in the U.S. diagnosed with AUD. Individuals with AUD often show cognitive impairment such as risky decision-making, difficulties with impulse control, and working memory deficits. This impairment is associated with structural and functional changes in the prefrontal cortex (PFC), an extensively interconnected region of the frontal lobe involved in executive control of goal-directed behaviors. Chronic alcohol exposure in rodents has been seen to cause deficits in performance in behavioral tasks which assess mPFC function such as working memory and behavioral flexibility. It is …
Connectional Analysis Of Brain Regions Associated With Feeding,
2023
University of Texas at El Paso
Connectional Analysis Of Brain Regions Associated With Feeding, Kenichiro Negishi
Open Access Theses & Dissertations
Rodent models are invaluable for understanding the foundations of motivatedbehaviors. One major obstacle faced by these efforts is the lack of a 'wiring diagram' or a 'parts list' of structures that support motivated behaviors. Here, I present work that advances our knowledge of the structural organization of connections and chemoarchitecture of the diencephalon. Chapter 1 aims to clarify a wiring diagram of the medial prefrontal cortex (mPFC) following a recent demonstration of cortically-evoked feeding through this region. Chapter 2 clarifies the distributions of a subpopulation of tyrosine hydroxylase (TH) neurons in the hypothalamus. These disparate datasets were analyzed and interpreted …
A Novel Neuroinvasive Infection Modality For Francisella Tularensis Elicits Neuroinflammation Resulting In Cellular Damage,
2023
University of Texas at El Paso
A Novel Neuroinvasive Infection Modality For Francisella Tularensis Elicits Neuroinflammation Resulting In Cellular Damage, Mireya Griselle Ramos-Muniz
Open Access Theses & Dissertations
Francisella tularensis (Ft.) is a gram-negative coccobacillus bacterium that causes the zoonotic disease tularemia in humans. Ft. causes the most severe, often fatal, form of the disease through inhalation. However, Ft. is most commonly transmitted through direct contact with infected animal carcasses such as rodents and rabbits, consumption of contaminated food or water, or through arthropod bites, particularly ticks. Due to its extremely low infectious dose, high mortality rate, and potential use as a biological warfare agent, Ft. is classified by the CDC as a "Tier 1 select agent". Ft. infection triggers an overactive inflammatory response, termed a "cytokine storm", …
Characterization Of Potential Genes Encoding For A Glycine Transporter From Drosophila Melanogaster,
2023
University of Texas at El Paso
Characterization Of Potential Genes Encoding For A Glycine Transporter From Drosophila Melanogaster, Denise Avalos
Open Access Theses & Dissertations
The study of glycine transporters has been neglected compared to other members of the Solute Carrier 6 (SLC6) family of proteins, such as the dopamine and serotonin transporters, even though they are just as crucial to survival. However, glycinergic neurotransmission has been extensively studied in mammals, resulting in vast, valuable information. The same cannot be said for invertebrates, however. In this study, we aim to establish an initial first step in elucidating components of glycinergic neurotransmission in the invertebrate, Drosophila melanogaster. We believe this organism possesses a glycine transporter because a glycine receptor has been identified and characterized. Specifically, we …
Long-Term Effects Of Juvenile Ketamine And/Or Social Stress Exposure On Spatial Memory Performance In C57bl/6 Mice,
2023
University of Texas at El Paso
Long-Term Effects Of Juvenile Ketamine And/Or Social Stress Exposure On Spatial Memory Performance In C57bl/6 Mice, Israel Garcia Carachure
Open Access Theses & Dissertations
Ketamine is administered to manage major depressive disorder in adolescent patients. However, the long-term effects of juvenile ketamine exposure on memory-related tasks have not been thoroughly assessed. Thus, we examined whether exposure to ketamine, psychological stress, or both, results in long-lasting alterations in spatial memory in C57BL/6 mice. Furthermore, we evaluated how ketamine and/or psychological stress history influenced hippocampal protein kinase b¬–mammalian target of rapamycin (AKT-mTOR)-related signaling, since this molecular cascade is associated with ketamine’s acute/fast-acting antidepressant properties. Male and female postnatal day (PD)-35 mice underwent 10-days of vicarious defeat stress (VDS), a form of psychological stress, with or without …
