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Identifying Pyle's Metaphyseal Dysplasia – An Incidental Finding Of Skeletal Pathology On A Dental Checkup, Shruthi Parthasarathy, Amudhan Azhagan, Arthisri Anandhi Sekar, Poongodi V, Ram Shankar 2026 1.* Department of Oral Medicine and Radiology Meenakshi Academy of Higher Education and Research (MAHER), Meenakshi Ammal Dental College and Hospital (MADC), Alapakkam main road, Maduravoyal, Chennai 600095 India.

Identifying Pyle's Metaphyseal Dysplasia – An Incidental Finding Of Skeletal Pathology On A Dental Checkup, Shruthi Parthasarathy, Amudhan Azhagan, Arthisri Anandhi Sekar, Poongodi V, Ram Shankar

Chulalongkorn Medical Journal

Introduction:

Pyle's disease, also known as familial metaphyseal dysplasia, is a rare autosomal recessive genetic disorder that primarily affects the skeletal system, particularly in children and adolescents. Characterized by distinctive radiographic features such as Erlenmeyer flask deformity and metaphyseal widening, Pyle's disease often goes underdiagnosed due to its mild clinical manifestations.

Case report:

This case report details a 15-year-old female patient presenting with retained milk teeth and unerupted permanent teeth, alongside notable skeletal abnormalities including genu valgum and kyphosis. Clinical and radiographic evaluations revealed significant dental anomalies, including multiple impacted permanent teeth and mild dysmorphic facial features. Although genetic testing …


Clinical Outcomes Of Adjunctive Use Of Oxygen-Releasing Formula In Non-Surgical Treatment Of Periodontal Abscess Associated With Type 2 Diabetes Mellitus, Anil Kumar Kanakamedala, Laxmi Kavya Gangireddy, Gautami S Penmetsa, Sruthima Gottumukkala, Mohan Kumar Pasupuleti, Konathala Santhosh Venkata Ramesh 2026 Department of Periodontics and Implantology, Vishnu Dental College, Bhimavaram 534202, India

Clinical Outcomes Of Adjunctive Use Of Oxygen-Releasing Formula In Non-Surgical Treatment Of Periodontal Abscess Associated With Type 2 Diabetes Mellitus, Anil Kumar Kanakamedala, Laxmi Kavya Gangireddy, Gautami S Penmetsa, Sruthima Gottumukkala, Mohan Kumar Pasupuleti, Konathala Santhosh Venkata Ramesh

Journal of Dentistry Indonesia

Background: This study aimed to evaluate the effectiveness of oxygen-releasing formula (ORF) as an adjunct in the non-surgical management of periodontal abscess in patients with type 2 diabetes mellitus.

Methods: This split-mouth clinical trial was conducted on 14 patients with periodontal abscess with type 2 diabetes mellitus (T2DM), who were divided into a control group, nonsurgical periodontal therapy (NSPT) alone, and a test group (NSPT+ORF). Parameters such as Landry's healing index (HI) were evaluated at 1 week, 2 weeks, and 1 month. Probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing presence or absence (BOP) …


Adverse Drug Reaction Reporting In Dental Practice And The Importance Of Pharmacovigilance In Dental Education, Radhakrishna Lagishetty, Lakshmi Ramya T, KVR Barath Raju, Mohan Kumar Pasupuleti 2026 Department of General and Dental Pharmacology, Vishnu Dental College, Bhimavaram 534202, India

Adverse Drug Reaction Reporting In Dental Practice And The Importance Of Pharmacovigilance In Dental Education, Radhakrishna Lagishetty, Lakshmi Ramya T, Kvr Barath Raju, Mohan Kumar Pasupuleti

Journal of Dentistry Indonesia

Background: Adverse drug reactions (ADRs) are a critical component of patient safety; however, ADR monitoring remains underutilized in dentistry. This study aimed to assess knowledge, attitudes, and practices regarding ADR reporting among undergraduate and postgraduate students and practicing dentists.

Methods: A cross-sectional observational study was conducted using a structured, validated 19-item questionnaire covering socio-demographics, knowledge (6 items), attitude (4 items), and practice (5 items), which was distributed both in person and online. A total of 258 complete responses were analyzed out of 300 individuals contacted (response rate: 86%). Descriptive statistics and Chi-square tests were applied, with p < 0.05 considered statistically significant.

Results …


Investigation Of Patients' Use Of Non-Pharmacological Substances In Dental Pain Management, Neslihan Yılmaz Çırakoğlu, Özgenur Kaya 2026 Department of Endodontics, Faculty of Dentistry, Karabük University, Karabük 78050, Türkiye

Investigation Of Patients' Use Of Non-Pharmacological Substances In Dental Pain Management, Neslihan Yılmaz Çırakoğlu, Özgenur Kaya

Journal of Dentistry Indonesia

Background: Dental pain is a complex condition influenced by biological, biochemical, environmental, and psychological factors. Before seeking professional care, many patients attempt to relieve dental pain using self-administered, non-medical agents. This study aimed to investigate patients’ use of non-pharmacological substances in dental pain management and to identify factors influencing these practices.

Methods: The questionnaire consisted of four sections addressing demographic characteristics, oral hygiene habits, pain characteristics, and pain-relief agents. Categorical variables were analyzed using Pearson’s chi-square test. Categorical data are presented as frequencies and percentages, while continuous data are expressed as mean ± standard deviation and median values. …


Orthodontic Camouflage Treatment Of A Severe Class Iii Skeletal Pattern With Anterior Open Bite: A Case Report, Dikeledi Maureen Letsholo, Mandla Dominic Nyakale, Mosimane Peter Silas Sethusa 2026 Department of Orthodontics, School of Dentistry, Sefako Makgatho Health Sciences University, Ga-Rankuwa 0204, South Africa

Orthodontic Camouflage Treatment Of A Severe Class Iii Skeletal Pattern With Anterior Open Bite: A Case Report, Dikeledi Maureen Letsholo, Mandla Dominic Nyakale, Mosimane Peter Silas Sethusa

Journal of Dentistry Indonesia

Background: Class III malocclusion combined with anterior open bite (AOB) is one of the most challenging occlusal problems to treat. The objective of this article was to report a case of an adult female patient diagnosed with Class III malocclusion combined with an anterior open bite and a hyperdivergent facial pattern.

Case Report: Camouflage orthodontic treatment with the extraction of maxillary and mandibular first premolars was used to treat the patient. Anterior teeth were retracted maximally against the Nance holding arch and fixed lingual arch appliances, and box elastics were used to close AOB. At the end of …


Management Of Skeletal Class Iii Malocclusion With Deep Bite And Moderate Overjet Using Improved Super-Elastic Ti-Ni Alloy Wire (Isw), Wen-Hsuan Lin, Ching-Yu Yang, Yuan-Hou Chen, Jian-Hong Yu 2026 Department of Orthodontics, China Medical University and Medical Center, Taiwan

Management Of Skeletal Class Iii Malocclusion With Deep Bite And Moderate Overjet Using Improved Super-Elastic Ti-Ni Alloy Wire (Isw), Wen-Hsuan Lin, Ching-Yu Yang, Yuan-Hou Chen, Jian-Hong Yu

Taiwanese Journal of Orthodontics

A 20-year-old female presented with concerns about poor dental alignment and a tendency to bite on her lip easily. Clinical examination revealed a concave and brachy facial profile, accompanied by a deep overbite and a moderate overjet. Radiographic examination showed skeletal Class III with a low mandibular plane angle. Correction of the deep bite was achieved by using the Improved Super-elastic Ti-Ni alloy Wire (ISW) and Intermaxillary elastics (IMEs). To correct the moderate overjet, interproximal reduction (IPR), the Multi-bend Edgewise Archwire (MEAW) technique, and arch lengthening of the lower arch were applied. The active treatment duration took approximately 54 months, …


Improved Super-Elastic Ti-Ni Alloy Wire For The Treatment Of Skeletal Class Iii Malocclusion With Anterior Crossbite And Missing Lower Molar, De-Lun Zhuang, Yuan-Hou Chen, Jian-Hong Yu 2026 Department of Orthodontics, China Medical University and Medical Center, Taiwan

Improved Super-Elastic Ti-Ni Alloy Wire For The Treatment Of Skeletal Class Iii Malocclusion With Anterior Crossbite And Missing Lower Molar, De-Lun Zhuang, Yuan-Hou Chen, Jian-Hong Yu

Taiwanese Journal of Orthodontics

This case report describes the use of Improved Super-elastic Ti-Ni alloy wire (ISW), developed by Tokyo Medical and Dental University, in managing a skeletal Class III malocclusion with anterior crossbite and a missing lower molar. A 26-year-old female presented with a chief complaint of poor dental alignment. Clinical and radiographic evaluation revealed Angle Class III malocclusion, anterior crossbite, a missing mandibular first molar (36), and a centric occlusion–centric relation (CO–CR) functional shift, consistent with a skeletal Class III pattern. Treatment involved the use of ISW for leveling and alignment of both arches and correction of the anterior crossbite, while maintaining …


Inferior Alveolar Nerve Proximity In Mandibular Molar Distalization: Implications For Orthodontic Treatment Planning, Samantha Hsien-Chu Mao, Chia-Hsuan Chan, Yu-Jen Chang, Shiu-Shiung Lin, Chen-Feng Cheng, Te-Ju Wu 2026 Department of Orthodontics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung, University College of Medicine, Kaohsiung, Taiwan

Inferior Alveolar Nerve Proximity In Mandibular Molar Distalization: Implications For Orthodontic Treatment Planning, Samantha Hsien-Chu Mao, Chia-Hsuan Chan, Yu-Jen Chang, Shiu-Shiung Lin, Chen-Feng Cheng, Te-Ju Wu

Taiwanese Journal of Orthodontics

Purpose: This study aimed to clarify the anatomical boundaries of mandibular molar distalization, emphasizing the risk of inferior alveolar nerve (IAN) contact. Patients and Methods: In total, 30 skeletal Class III patients undergoing orthognathic surgery (59 mandibular hemi-arches) were analyzed using pretreatment three-dimensional (3D) computed tomography scans. The shortest horizontal distance between the mandibular second molar and the inferior alveolar canal (M2-IAC) was measured at multiple depths below the cementoenamel junction, along with the distance to the lingual cortical plate (M2-MLC). Samples were categorized by vertical facial pattern (low-, normal-, and high-angle case). Simulated distalization cases predicting IAN contact were …


Comparative Evaluation Of Selected Properties Of Tetrahedral Amorphous Carbon (Ta-C) Coated And Uncoated Beta Titanium (Β-Ti) Archwires - An In Vitro Study, Abhinaya Jotheswaran, Kurunji Kumaran Navaneethakrishnan 2026 Sitara Dental and Orthodontic Centre, Bengaluru, Karnataka, India

Comparative Evaluation Of Selected Properties Of Tetrahedral Amorphous Carbon (Ta-C) Coated And Uncoated Beta Titanium (Β-Ti) Archwires - An In Vitro Study, Abhinaya Jotheswaran, Kurunji Kumaran Navaneethakrishnan

Taiwanese Journal of Orthodontics

Objective: The development of newer archwires can be achieved either by discovering novel materials or by modifying existing ones. The objective of the present study was to coat beta-titanium (β-Ti) archwires with tetrahedral amorphous carbon (ta-C)/hard carbon and to evaluate selected physical and mechanical properties. Methods: Hard carbon–coated (n = 5) and uncoated (n = 5) β-Ti wires were assessed for surface roughness, wear resistance, load-deflection characteristics, and friction using appropriate testing apparatus under dry in vitro conditions. Results: Compared to uncoated β-Ti wires, ta-C–coated β-Ti wires demonstrated a statistically significant reduction in surface roughness, increased wear resistance, and lower …


Evaluation Of Optimal Force For Intrusion Of A Periodontally Compromised Maxillary Anterior Dentition Treated With Fixed Orthodontics – A Finite Element Analysis, Tanzim Ahmed, Amrita Puri, Aatira Nair, Anshul Singla, Mathew Koshy Vaidyan, Shruti Sharma, Chhavi Singh 2026 Institute of Technology and Science

Evaluation Of Optimal Force For Intrusion Of A Periodontally Compromised Maxillary Anterior Dentition Treated With Fixed Orthodontics – A Finite Element Analysis, Tanzim Ahmed, Amrita Puri, Aatira Nair, Anshul Singla, Mathew Koshy Vaidyan, Shruti Sharma, Chhavi Singh

International Arab Journal of Dentistry

Introduction: Adult orthodontic treatment is increasingly sought due to aesthetic and functional concerns, often involving periodontally compromised patients with altered biomechanics. Reduced bone support shifts the center of resistance and necessitates lower, carefully controlled forces, while finite element modeling has become a key tool to analyze tissue response under such conditions.

Objectives: The study aimed to determine the optimal intrusive force for periodontally compromised maxillary anterior teeth using Finite Element Analysis (FEA).

Methods: A 3D finite element model of the maxillary anterior dentition was created and divided into healthy and compromised halves, the latter with one-third alveolar bone loss. A …


The Efficacy Of Mini-Screw Rapid Palatal Expansion (Marpe) In Late Adolescents And Young Adults: A Systematic Review, Afaf El Merouani Drissi, Hajar Ben Mohimd, Hicham Benyahia, Fatima ZAOUI 2026 Université Mohammed V de Rabat, Faculté de Médecine dentaire de Rabat

The Efficacy Of Mini-Screw Rapid Palatal Expansion (Marpe) In Late Adolescents And Young Adults: A Systematic Review, Afaf El Merouani Drissi, Hajar Ben Mohimd, Hicham Benyahia, Fatima Zaoui

International Arab Journal of Dentistry

Introduction: Mini-screw assisted rapid maxillary expansion (MARPE) emerged as a less invasive alternative treatment for transverse maxillary expansion, and designed to overcome the limitations of conventional rapid maxillary expansion for patients from post-pubertal growth spurt period onwards, often presenting with an interdigitated suture. The aim of this systematic review is to evaluate the efficacy of this treatment on skeletal, dento-alveolar and periodontal levels based on CBCT studies, by comparing it to the conventional rapid maxillary expansion (RPE).

Methods: a literature search of five databases (PubMed, Scopus, Web of Science, ScienceDirect and the Cochrane library) was conducted from 2010 until July …


The Effectiveness Of Anterior Torque Control By Clear Aligners In Extraction And Non-Extraction Cases : Systematic Review, Houda Ousli, Kawtar Chadli, Fatima Zaoui, Hicham Benyahia 2026 Department of dentofacial orthopedics, Faculty of Dental Medicine, University of Mohammed V. Rabat. Morocco

The Effectiveness Of Anterior Torque Control By Clear Aligners In Extraction And Non-Extraction Cases : Systematic Review, Houda Ousli, Kawtar Chadli, Fatima Zaoui, Hicham Benyahia

International Arab Journal of Dentistry

Introduction: Clear aligner treatment has gained popularity in recent years. Accurate torque expression of the upper incisors is crucial for orthodontic treatment outcomes but remains challenging in invisible orthodontic treatment.

Objectives: This systematic review aims to evaluate the existing literature and critically assess the clinical effectiveness of aligners in controlling anterior torque or bucco-lingual root inclination, in both extraction and non-extraction cases.

Methods: A systematic search of Scopus, PubMed, Web of Science, Ebsco, and the Cochrane Library was conducted for peer-reviewed articles published between 2014 and March 2025. A total of 257 records were identified (Scopus: 32; Web of Science: …


A Comparison Of Changes In Vertical Cephalometric Measurements In Patients Treated With Invisalign And Traditional Fixed Orthodontic Appliances: A Retrospective Study, Shayna Mesko 2026 University of Nevada, Las Vegas

A Comparison Of Changes In Vertical Cephalometric Measurements In Patients Treated With Invisalign And Traditional Fixed Orthodontic Appliances: A Retrospective Study, Shayna Mesko

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Since their introduction into the field, clear aligners have significantly grown in popularity in orthodontics as they offer enhanced esthetics, improved oral hygiene, and patient comfort. Clear aligners have allowed clinicians to simulate treatment outcomes, streamline treatment with reduced office visits, control force and movement per tray, and provide more precise control of focal tooth movements. This can enhance efficiency in achieving specific and very finite orthodontic goals. Since their inception, clear aligners have evolved from only accomplishing simple tooth movements to achieving more complex and comprehensive mechanics. While they have significantly advanced, there are still limitations in efficacy …


Asymmetric Maxillary Molar Distalization And Guided Canine Eruption Using Temporary Anchorage Devices And Super-Elastic Niti Wire, Kah-Ying Yim, Huei-Mei Tsai, Yu-Ling Cheng, Ming-Jeaun Su, Yi-Min Liu 2026 Dr. Su’s Teamwork Orthodontic Center, Taipei, Taiwan

Asymmetric Maxillary Molar Distalization And Guided Canine Eruption Using Temporary Anchorage Devices And Super-Elastic Niti Wire, Kah-Ying Yim, Huei-Mei Tsai, Yu-Ling Cheng, Ming-Jeaun Su, Yi-Min Liu

Taiwanese Journal of Orthodontics

An adult female patient presented with a pronounced maxillary dental midline deviation and localized crowding in the upper right quadrant, particularly involving the canine and second molar. The maxillary right canine was buccally erupted and overlapped the lateral incisor and first premolar due to insufficient arch space and unfavorable root proximity. The mandibular arch exhibited mild anterior crowding with a flat curve of Spee. Orthodontic treatment was initiated using preadjusted fixed appliances. Extraction of the maxillary right third molar was performed to allow immediate sequential distalization of the maxillary right molars. A bypassed-canine main archwire in combination with a temporary …


Management Of Lower Incisor Protrusion In An Angle Class Iii Malocclusion Using Improved Super-Elastic Ti-Ni Alloy Wire, Jr-Wei Jian, Yu-Hsiang Chang, Yi-Mien Cheng, Ming-Han Cheng, Jian-Hong Yu 2026 Department of Orthodontics, China Medical University Hospital Medical Center

Management Of Lower Incisor Protrusion In An Angle Class Iii Malocclusion Using Improved Super-Elastic Ti-Ni Alloy Wire, Jr-Wei Jian, Yu-Hsiang Chang, Yi-Mien Cheng, Ming-Han Cheng, Jian-Hong Yu

Taiwanese Journal of Orthodontics

A 16-year-old adolescent female presented with the chief complaint of poor dental alignment and protrusion of the lower teeth. Clinical examination revealed Angle Class III malocclusion accompanied by lower anterior crowding and a protrusive lip profile involving both the upper and lower lips. Cephalometric analysis demonstrated a skeletal Class I relationship with a normal mandibular plane angle. To facilitate anterior retraction, four premolars (15, 24, 34, and 45) were extracted. Following extraction, Improved Super-elastic Ti-Ni alloy wire (ISW) was employed to relieve lower anterior crowding. Canine distalization and anterior retraction were subsequently performed. Elastic chains were used to assist midline …


Comparative Effectiveness Of Single Versus Two Miniscrews For Maxillary Incisor Intrusion In Gummy Smile: A Systematic Review And Meta-Analysis, Vaibhav Sunil Zanwar, Santosh Jetu Chavan, Jyoti Sunny Manchanda, Sakshi Santoshkumar Jain, Vedant S, Rishika Arya 2026 Department of Orthodontics & Dentofacial Orthopedics, Government Dental College & Hospital, Nagpur, Maharashtra, India

Comparative Effectiveness Of Single Versus Two Miniscrews For Maxillary Incisor Intrusion In Gummy Smile: A Systematic Review And Meta-Analysis, Vaibhav Sunil Zanwar, Santosh Jetu Chavan, Jyoti Sunny Manchanda, Sakshi Santoshkumar Jain, Vedant S, Rishika Arya

Taiwanese Journal of Orthodontics

Background: Orthodontic intrusion of maxillary incisors is commonly used to treat gummy smiles in deep bite patients. The effectiveness of using one versus two miniscrews for this purpose remains debated. This systematic review and meta-analysis aimed to compare the dental effects of one versus two miniscrews for maxillary incisor intrusion.

Materials and Methods: A literature search was conducted across multiple databases for studies published up to December 31, 2024. Five studies (four randomized controlled trials and one non-randomized study) met the inclusion criteria. Risk of bias was assessed using the RoB 2 and ROBINS-I tools.

Results: Intrusion was greater in …


Correlation Between Maxillary Incisor Inclination And Buccopalatal Alveolar Bone Thickness Assessed By Cbct: A Retrospective Observational Study, Raee Korgaonkar, Nandini Kamat 2026 Department of Orthodontics and Dentofacial Orthopedics, Goa Dental College and Hospital, Bambolim, India.

Correlation Between Maxillary Incisor Inclination And Buccopalatal Alveolar Bone Thickness Assessed By Cbct: A Retrospective Observational Study, Raee Korgaonkar, Nandini Kamat

Taiwanese Journal of Orthodontics

Purpose: This retrospective study aimed to evaluate the correlation between buccal and palatal alveolar bone thickness and the degree of maxillary incisor inclination. The objective was to derive clinically relevant insights for orthodontic treatment planning and controlled tooth movement. Materials and Methods: Sixty-one maxillary central incisors from cone-beam computed tomography (CBCT) scans of thirty-four subjects were retrospectively evaluated and grouped as proclined, upright, and retroclined incisors. Buccal and palatal thicknesses of cortical and cancellous alveolar bone were measured at various levels of the incisor root. The correlation between bone thickness and incisor angulation was investigated using Spearman’s correlation test. Results: …


Evaluation Of Mandibular Buccal Shelf Bone Thickness And Height For Miniscrew Placement Using Cone-Beam Computed Tomography, Roji Shrestha, Rabindra Man Shrestha, Jyoti Dhakal, Sujita Shrestha 2026 Department of Orthodontics, Kantipur Dental College, Kathmandu, Nepal

Evaluation Of Mandibular Buccal Shelf Bone Thickness And Height For Miniscrew Placement Using Cone-Beam Computed Tomography, Roji Shrestha, Rabindra Man Shrestha, Jyoti Dhakal, Sujita Shrestha

Taiwanese Journal of Orthodontics

Introduction: Buccal shelf area (BSA) is a recommended anatomic site for mini-screw insertion. Stability of miniscrew is determined by quantity of bone available in the region.

Objective: To determine bone thickness and height of BSA for optimum placement of miniscrew.

Materials and Methods: This cross-sectional observational study included 40 cone-beam computed tomography (CBCT) scans (23 males, 17 females) of patients aged 19-38 years. Patients were further divided into two age groups 19-28 years and 29-38 years. Measurements were made at 4 different sites: mandibular first molar mesial root (M6) and distal root (D6), second molar mesial root …


In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami 2026 Faculty of Dentistry, Lambung Mangkurat University, Banjarmasin, Indonesia

In Silico Model Of Musa Acuminata Stem As An Anticancer On Oral Squamous Cell Carcinoma Against Egfr, Nevrila Dewi Rachmayani, Amy Nindia Carabelly, I Wayan Arya Krishnawan Firdaus, Maharani Laillyza Apriasari, Juliyatin Putri Utami

Journal of Dentistry Indonesia

Background: Oral squamous cell carcinoma (OSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR). Citral, eucalyptol, and caffeic acid phenethyl ester (CAPE), which are derived from Musa acuminata, have shown anticancer activity. This study evaluated the potential of citral, eucalyptol, and CAPE from Musa acuminata as anticancer agents for OSCC by targeting EGFR using an in silico approach.

Methods: Potential biological activity was predicted using Prediction of Activity Spectra for Substances (PASS) Online. Molecular docking was conducted with AutoDock Vina, and BIOVIA Discovery Studio was used to analyze binding affinity, interaction types, and bond …


Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu 2026 Department of Endodontics, Faculty of Dentistry, Ankara Yıldırım Beyazıt University, Ankara, Türkiye

Micro-Ct Evaluation Of Root Canal Transportation And Centering Ability In Mesial Canals Of Mandibular First Molars, Selen Ince Yusufoglu, Esma Saricam, Mert Ocak, Ferhat Geneci, Burak Bilecenoğlu

Journal of Dentistry Indonesia

Background: This study aimed to evaluate canal transportation, centering ability, structure model index (SMI), surface area, and root canal volume changes in the mesial canals of mandibular first molars using micro-CT.

Methods: Twenty-four mandibular first molars with two separate mesial canals and moderate curvature were included. Teeth were scanned using micro-CT before instrumentation and randomly divided into three groups (N = 8). Root canals were prepared using OneShape, OneCurve, and Rotate file systems, followed by post-instrumentation micro-CT scanning (10µm/pixel resolution). Changes in canal volume, surface area, transportation, centering ability, and SMI were analyzed at the apical, middle, and …


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