Computer Sciences Commons^™

Clinicians In The Loop Of Medical Ai, W. Nicholson Price Ii

Articles

As medical AI begins to mature as a health-care tool, the task of governance grows increasingly important. Ensuring that medical AI works, works where it’s used, and works for the patient in the moment is a challenging, multifaceted task. Some of this governance can be centralized—in review by FDA or by national accreditation labs, for instance. Some must be local, performed by the hospital or health system about to use the product in their own, unique environment. But a large amount of governance is left to the individual provider in the room, the human in the loop who presumably knows …

Do Specialized Medical Llms Demand A Radically New Approach Under The Eu's Medical Device Regulation, Hannah Louise Smith, W. Nicholson Price Ii

Articles

We examine the arguments made by Onitiu and colleagues concerning the need to adopt a “backward-walking logic” to manage the risks arising from the use of Large Language Models (LLMs) adapted for a medical purpose. We examine what lessons can be learned from existing multi-use technologies and applied to specialized LLMs, notwithstanding their novelty, and explore the appropriate respective roles of device providers and regulators within the ecosystem of technological oversight.

Boden Lecture: Taxation Of Autonomous Artificial Intelligence, Reuven S. Avi-Yonah, Lucas Brasil Salama, Herbert Snitz, W. Robert Thomas

Articles

This Article proposes that tax can be a useful supplement to other measures to regulate Autonomous Artificial Intelligence (AAI) and limit its potential harmful effects. This proposal differs from command-and-control regulation of AAI along the lines of European Union legislation that may unduly limit the development of AAI. It also differs from existing proposals to tax AAI to generate revenue to help workers displaced by AAI programs, or to tax the data used by AAI The proposal is based on granting AAI programs like ChatGPT separate legal personhood, like corporate personhood, while incentivizing or requiring their corporate owner to place …

Synthetic Data Generation Of Health And Demographic Surveillance Systems Data: A Case Study In A Low- And Middle-Income Country, Dorcas G. Mwigereri, Nigel T. Kamotho, Akbar K. Waljee, Ryan T. Rego, Eileen M. Weinheimer-Haus, Farhana Alarakhiya, Anthony K. Ngugi, W. Nicholson Price, Ji Zhu, Stephen Peter Wong, Geoffrey H. Siwo

Articles

Objective: To evaluate effectiveness of open-source generative models in producing high-quality tabular synthetic data using a Health and Demographic Surveillance System (HDSS) dataset from rural Kenya, as a proof of concept in a low- and middle-income (LMIC) setting.

Materials and Methods: Three open-source models (CTGAN, TableGAN, and CopulaGAN) were used to generate synthetic data from the Kaloleni/ Rabai HDSS dataset. To assess the quality of the synthetic datasets generated by each model, we performed fidelity, utility, and privacy tests.

Results: CTGAN outperformed the other models, producing synthetic data that closely mirrored the statistical properties of the real dataset while preserving …

The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, W. Nicholson Price Ii, Arti Rai

Articles

As artificial intelligence (AI) transforms drug development, regulatory frameworks are evolving to oversee its implementation, particularly at the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This paper makes three contributions to understanding emerging regulatory approaches. First, we offer a comparative analysis of how these agencies have responded to AI-driven advances, incorporating new US executive orders and the European Union (EU)’s AI Act. Second, we propose a novel analytical framework to understand regulatory divergence: the FDA’s flexible, dialog-driven model contrasts with the EMA’s structured, risk-tiered approach, reflecting broader institutional and political-economic differences. While the former encourages …

Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organisms rely on behavior for survival. Animals engage in behaviors that allow for feeding, mating, exploring and navigating their environment among others. Necessary for these behaviors to develop are the environmental factors and underlying circuitry which make behavior possible. Specifically, how the environment guides underlying neural circuitry to develop unique facets or phenotypes of a larger behavior are key to understanding why unique behaviors exist. In this thesis, I build foundational evidence for determining these mechanisms through the use of the zebrafish local search behavior. This is a behavior that zebrafish employ following the loss of environmental illumination where they …

Development And Application Of Computational Tools For Data-Driven Materials Science., Logan L. Lang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Modern materials science generates vast amounts of data from computational simulations and experiments, creating significant challenges for data processing and analysis. This thesis addresses these challenges through the development and application of computational tools within the framework of Material Data Science (MDS). Contributions span the four pillars of MDS: Material/Molecular Data, Algorithms, Databases, and High-Throughput Processes—with a primary focus on the Algorithm, Data, Database pillars.

For the Algorithm pillar, two Python libraries were developed to streamline common analysis tasks. PyProcar simplifies the post-processing and visualization of electronic structure data (band structures, density of states, Fermi surfaces) obtained from various Density …

Using Visual Prompts To Analyze Ejection Fraction In Echocardiograms, Kevin Reisch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Left ventricular ejection fraction (LVEF) is a critical biomarker for heart failure, but manual estimation from echocardiograms is time-consuming. Artificial intelligence can be used to accelerate this process, allowing clinicians to focus on other critical tasks. Current methods typically train models from scratch on echocardiogram datasets; however, this approach is limited by the scarcity of large medical imaging datasets, which are expensive and difficult to acquire. We present a transfer learning approach that leverages pretrained models from massive datasets, enabling continuous improvement as foundation models advance. Our method employs visual prompting to generate trainable masks for echocardiogram videos, transforming the …

The Effect Of Facial Phenotypes On Differential Performance Of Facial Recognition, Evan R. Garrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

Facial recognition technology is utilized in many facets of life. As the use has become more widespread these systems have improved in reliability and performance approaching the level of human accuracy. With these improvements the problem of bias still remains as a persistent problem. Efforts have been made to minimize the bias prevalent in the systems via studies into various demographic factors, creating training datasets that have a more uniform distribution of subjects, and other methods. As facial recognition is one of the most utilized forms of biometric recognition it is vital to analyze potential causes of bias to help …

Simulation Of Annpet For Neural Network Training And System Performance Benchmarking, Pete Martone

Graduate Theses, Dissertations, and Problem Reports (ETD)

Monte Carlo (MC) simulations are often used to provide insight into complex physical phenomenon. They can generate realistic results without the necessity to construct costly and complex apparatus. The ultimate value of these simulations depend on how accurately the physics can be modeled and if a sufficient volume can be produced to account for statistical variance. In medical imaging device development, MC simulations of Positron Emission Tomography (PET) scanners have typically been used to model the performance of new systems. The imaging group in the Department of Radiology have developed a unique detector design for a pre- clinical PET scanner …

Applications Of Deep Learning For Optimizing Fingerphoto And Latent Fingerprint Biometrics, Amol Sanjay Joshi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fingerprint-based biometric recognition remains one of the most dependable and widely adopted approaches for identity verification due to its permanence and distinctiveness. Recent advancements in mobile and contactless imaging have extended fingerprint acquisition beyond controlled environments into unconstrained, real-world conditions through fingerphotos, contactless fingerprint images captured by digital or smartphone cameras. While this paradigm shift enhances accessibility and user convenience, it introduces significant technical challenges. Variations in illumination, focus, and motion blur often degrade ridge patterns, making accurate feature extraction and matching more difficult. Similarly, in forensic applications, latent fingerprints, incomplete or smudged prints lifted from surfaces, pose unique challenges …

Individual And Collective Properties Of Tunable Photochemical Belousov-Zhabotinsky Micro-Reactors, Kudakwashe Benedict Shumba

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cell-like model chemical systems are powerful tools that can be used to explore the role of intercellular coupling on population level behaviors in communities of biological cells. Firstly, we present a new method for fabricating such micro-reactors using the photosensitive Belousov–Zhabotinsky (BZ) reaction system employed in silica microparticles. These BZ micro-reactors have a tunable response to photochemical coupling, varying from a fully excitatory response to a fully inhibitory response. Their response can be tuned through variations in either the reactive mixture or, on an individual micro-reactor level, by changes in the synthesis temperature used during the fabrication of the silica …

Toward Privacy-Preserving Data Sharing - An Australian Healthcare Perspective, Kimley Foster, Nectarios Costadopoulos, Arash Mahboubi, Sabih Ur Rehman, Md Zahidul Islam

Research outputs 2022 to 2026

The rise of big data has brought increased urgency to the importance of privacy-preserving data sharing in healthcare. In Australia, health records exist in various databases; however data sharing is limited. While many consumers and healthcare professionals recognise the advantages of sharing data for research and health care services, misgivings about privacy and security persist. This study examined current perspectives on data sharing, investigating the trust level in privacy preserving data sharing tools and techniques among healthcare professionals and organisations, and their openness to adopting technology for secure data sharing. We incorporated participants from various healthcare professions across Australia. We …

Protocol For An Integrative Meta-Analysis Of The Application Of Machine Learning Algorithms In The Prediction Of Chronic Disease Risks And Outcomes, Ebenezer Afrifa-Yamoah, Emmanuel Peprah-Yamoah, Enoch Odame Anto, Victor Opoku-Yamoah, Eric Adua

Research outputs 2022 to 2026

Background: Precise risk prediction of chronic diseases is essential for effective preventive care and management. Machine learning (ML) is a promising avenue to enhance chronic disease risk prediction; however, a comprehensive assessment of ML performance across various chronic diseases, populations, and health settings is needed. Methods: This meta-analysis aims to synthesize evidence on the performance of ML techniques for predicting the risks and outcomes of chronic diseases. A literature search was conducted through PubMed, Web of Science, Scopus, Science Direct, Medline, and Embase. Studies applying ML techniques to predict chronic disease risks or outcomes and reporting performance metrics were included. …

Zero Day Ransomware Detection With Pulse: Function Classification With Transformer Models And Assembly Language, Matthew Gaber, Mohiuddin Ahmed, Helge Janicke

Research outputs 2022 to 2026

Finding automated AI techniques to proactively defend against malware has become increasingly critical. The ability of an AI model to correctly classify novel malware is dependent on the quality of the features it is trained with and the authenticity of the features is dependent on the analysis tool. Peekaboo, a Dynamic Binary Instrumentation tool defeats evasive malware to capture its genuine behaviour. The ransomware Assembly instructions captured by Peekaboo, follow Zipf's law, a principle also observed in natural languages, indicating Transformer models are particularly well-suited to binary classification. We propose Pulse, a novel framework for zero day ransomware detection with …

Genai’S Impact On Global It Management: A Multi-Expert Perspective And Research Agenda, Yogesh K. Dwivedi, Laurie Hughes, Mohammad S. Al-Ahmadi, Vincent Dutot, Syed Q. Ahmed, Shahriar Akter, Rahul De’, Keyao Li, Nitish Singh, Paul Walton

Research outputs 2022 to 2026

Generative AI (GenAI) is disrupting global IT management and challenging established practice. The increasing use of GenAI technology is redefining localization, transforming existing workforce roles, outsourcing strategy, and team dynamics. Simultaneously, GenAI’s security complexities have prompted the rethinking of existing risk frameworks to meet a new set of challenges from GenAI enhanced cyber threats. This article explores these complex and converging factors, providing a roadmap to address GenAI’s significant impact on global IT management. We advocate the responsible adoption of GenAI and importance of building resilient, value-driven, globally consistent IT ecosystems able to adapt to the significant challenges and opportunities …

Blockchain-Based Trust Model For Inter-Domain Routing, Qiong Yang, Li Ma, Sami Ullah, Shanshan Tu, Hisham Alasmary, Muhammad Waqas

Research outputs 2022 to 2026

Border Gateway Protocol (BGP), as the standard inter-domain routing protocol, is a distance-vector dynamic routing protocol used for exchanging routing information between distributed Autonomous Systems (AS). BGP nodes, communicating in a distributed dynamic environment, face several security challenges, with trust being one of the most important issues in inter-domain routing. Existing research, which performs trust evaluation when exchanging routing information to suppress malicious routing behavior, cannot meet the scalability requirements of BGP nodes. In this paper, we propose a blockchain-based trust model for inter-domain routing. Our model achieves scalability by allowing the master node of an AS alliance to transmit …

Gans And Synthetic Financial Data: Calculating Var*, David E. Allen, Leonard Mushunje, Shelton Peiris

Research outputs 2022 to 2026

Generative Adversarial Neural nets (GANs) are a new branch of machine learning techniques. A GAN learns to generate new data from the training data set. We examine the characteristics of the fake financial data using GANs trained on samples of daily S&P 500 and FTSE 100 index values. GANs feature two competing neural networks in a game theoretic context. The Generator net generates pseudo data that is presented to the discriminator net which then attempts to distinguish between the real and the fake data. This facilitates unsupervised learning on the dataset. The generative network generates data sets, while the discriminative …

Joint 3d Beamforming-And-Trajectory Design For Uav-Satellite Uplink Covert Communication, Jihong Yu, Yuting Cai, Shihao Yan, Yun Li, Jingjing Wang, Jiahao Liu, Jianping An

Research outputs 2022 to 2026

In this paper,we study uplink covert communication in a space-air system,where an unmanned aerial vehicle (UAV) transmits sensitive data to a Geosynchronous Earth Orbit (GEO) satellite while preventing the transmission action from being discovered by a warden. We derive the optimal decision threshold of the warden. We investigate the 3-dimensional (3D) beamformer and 3D trajectory design for the transmitter UAV against this optimum warden to maximize the covert transmission rate in the presence of imperfect channel state information and uncertain noise. Due to the non-convex structure and dependence between beamforming vectors and locations of the transmitter UAV,we develop a decoupling …

Techmate: A Toolkit For Advancing Gender Equality In Computing Education, Alina Berry

Academic Posters Collection

To address the issue of gender inequality in computing education.

To inspire and guide institutions to implement change and track progress with easy to follow guidance.

To provide champions with useful and easy to access resources.

Navigating Together: The Conav Testbed And Framework For Benchmarking Cooperative Localization, Rohith Boyinine, Jayanth Ammapalli, Anusna Chakraborty, Rajnikant Sharma, Kevin Brink, Clark N. Taylor

Faculty Publications

This paper presents CoNaV, a comprehensive framework for creating a multi-vehicle cooperative localization (CL) testbed designed to support the benchmarking, development, and deployment of cooperative navigation algorithms. Given the essential role of CL in improving localization accuracy for both defense and civilian applications, CoNaV provides a robust environment for rigorously validating algorithms under real-world conditions. By establishing a benchmark for CL algorithms, CoNaV lays a foundation for advancing research into more sophisticated and distributed CL solutions. This framework highlights the potential of cooperative navigation to enhance multi-vehicle operations and offers a scalable, practical approach for future developments in CL technology.

On-Device Recommender Systems: A Comprehensive Survey, Hongzhi Yin, Liang Qu, Tong Chen, Wei Yuan, Ruiqi Zheng, Jing Long, Xin Xia, Yuhui Shi, Chengqi Zhang

Research outputs 2022 to 2026

Recommender systems have been widely deployed in various real-world applications to help users identify content of interest from massive amounts of information. Traditional recommender systems work by collecting user-item interaction data in a cloud-based data center and training a centralized model to perform the recommendation service. However, such cloud-based recommender systems (CloudRSs) inevitably suffer from excessive resource consumption, response latency, as well as privacy and security risks concerning both data and models. Recently, driven by the advances in storage, communication, and computation capabilities of edge devices, there has been a shift of focus from CloudRSs to on-device recommender systems (DeviceRSs), …

Towards Robust Multimodal Land Use Classification: A Convolutional Embedded Transformer, Muhammad Zia Ur Rehman, Syed Mohammed Shamsul Islam, Anwaar Ulhaq, David Blake, Naeem Janjua

Research outputs 2022 to 2026

Multisource remote sensing data has gained significant attention in land use classification. However, effectively extracting both local and global features from various modalities and fusing them to leverage their complementary information remains a substantial challenge. In this paper, we address this by exploring the use of transformers for simultaneous local and global feature extraction while enabling cross-modality learning to improve the integration of complementary information from HSI and LiDAR data modalities. We propose a spatial feature enhancer module (SFEM) that efficiently captures features across spectral bands while preserving spatial integrity for downstream learning tasks. Building on this, we introduce a …

Enhancing Cybersecurity Through Autonomous Knowledge Graph Construction By Integrating Heterogeneous Data Sources, Hatoon Alharbi, Ali Hur, Hasan Alkahtani, Hafiz Farooq Ahmad

Research outputs 2022 to 2026

Cybersecurity plays a critical role in today’s modern human society, and leveraging knowledge graphs can enhance cybersecurity and privacy in the cyberspace. By harnessing the heterogeneous and vast amount of information on potential attacks, organizations can improve their ability to proactively detect and mitigate any threat or damage to their online valuable resources. Integrating critical cyberattack information into a knowledge graph offers a significant boost to cybersecurity, safeguarding cyberspace from malicious activities. This information can be obtained from structured and unstructured data, with a particular focus on extracting valuable insights from unstructured text through natural language processing (NLP). By storing …

Novel Digital Twin Deployment Approaches: Local And Distributed Digital Twin, Shahid Rauf, Fazal Muhammad, Akhtar Badshah, Hisham Alasmary, Muhammad Waqas, Sheng Chen

Research outputs 2022 to 2026

The Digital Twin (DT) technology is considered as a backbone in the Industrial 4.0 revolution as it is playing a vital role in the digitization of various industries. A DT is a virtual representation of a physical entity, thus having the ability to simulate real data generated at physical space to optimize, estimate, control, monitor and forecast states/configurations. Despite enormous benefits, DT technology has several implementation challenges. Although deploying DT on edge or cloud platforms yields a plethora of services, its implementation in both spaces faces certain limitations. These limitations include latency, data communication overload, transmission energy consumption, privacy concerns, …

Panoscu: A Simulation-Based Dataset For Panoramic Indoor Scene Understanding, Mariia Khan, Yue Qiu, Yuren Cong, Jumana Abu-Khalaf, David Suter, Bodo Rosenhahn

Research outputs 2022 to 2026

Panoramic images offer a comprehensive spatial view that is crucial for indoor robotics tasks such as visual room rearrangement, where an agent must restore objects to their original positions or states. Unlike existing 2D scene change understanding datasets, which rely on single-view images, panoramic views capture richer spatial context, object relationships, and occlusions—making them better suited for embodied artificial intelligence (AI) applications. To address this, we introduce Panoramic Scene Change Understanding (PanoSCU), a dataset specifically designed to enhance the visual object rearrangement task. Our dataset comprises 5,300 panoramas generated in an embodied simulator, encompassing 48 common indoor object classes. PanoSCU …

Improving Chatbot Interactions Through Ai-Driven Hate Speech Detection: Evolving To A Safer Digital Environment-Poster, Rata Gheorghita, Wellington Mariano

ICT

This project aims to explore how Machine Learning can contribute to a better digital interaction, mainly focusing on environments such as online chats, social media, and customer support as they are now an imperative part of daily communication. With this, concerns around hate speech in digital conversations is critical (Council of Europe, 2024). This study focus on the development of a Hate Speech Language Detection Chatbot using machine learning techniques. The key purpose of the chatbot is to monitor and detect harmful content in real time, reducing the need for manual intervention. The creation and implementation of such a tool …

Deep Learning For Irish Garden Bird Identification: Exploring The Role Of Cnn-Lstm In Video-Based Recognition, Antonina Dolynenko

ICT

Bird populations are widely used as indicators of ecosystem health, but traditional monitoring based on manual observation is labour-intensive and difficult to scale. Recent advances in deep learning and low-cost edge hardware offer new opportunities for automated, real-time bird identification in gardens and other local habitats. This thesis investigates whether video-based deep learning models can reliably classify common Irish garden birds from short motion-triggered clips and how temporal modelling compares to image-based models.

A primary dataset of 20-second clips was collected in a private garden in Ireland using a Raspberry Pi with a high-resolution camera and a YOLO-based trigger to …

Kangaroo: Dynamic Fusion Of Branch Instructions In A Pipelined Uniprocessor, Sarah E. Larkin

Dissertations, Master's Theses and Master's Reports

Small pipelined processors are becoming more common as a complement to superscalars in a multi-core chip. However, current uniprocessors offer little in the way of ILP. We present kangaroo, a novel approach to instruction fusion in a pipelined processor. Kangaroo dynamically fuses two adjacent instructions to create a pair that travels through the pipeline as a unit. The instructions re-enter the pipeline as a pair the next time the first instruction is fetched. Unlike in prior art, an instruction, once fused, is not fetched again. Any pair of adjacent instructions can be fused using this technique, including dependent instructions. …

Generalizing Medical Image Segmentation Task With Efficient Deep Learning Models, Abel A. Reyes-Angulo

Dissertations, Master's Theses and Master's Reports

Medical Image Segmentation is a critical task in the field of medical imaging, playing a crucial role in diagnostics, treatment planning, and disease monitoring. The emergence of Deep Learning (DL) has ushered in a new era in Artificial Intelligence (AI), propelling remarkable advancements in key domains like language translation, object recognition, and recommendation systems. This evolution has been accompanied by continuous enhancements in computational efficiency and improvements in predictive accuracy. The introduction of sophisticated algorithms, such as convolutional neural networks (CNNs) and transformers, exemplifies these advancements. DL algorithms have demonstrated exceptional efficacy in medical image segmentation tasks, showcasing the potential …