Computer Sciences Commons^™

Machine Learning For Computer-Aided Diagnostics From Complex Medical Images, Afsah Saleem

Theses: Doctorates and Masters

Machine learning has significantly transformed medical image analysis in the current age of artificial intelligence offering vast potential in improving disease diagnosis and management. Cardiovascular diseases (CVDs) are among the leading cause of global mortality, emphasizing the need for early detection for effective intervention and prevention. Abdominal Aortic Calcification (AAC) is an early indicator and contributor to Atherosclerotic Cardiovascular Diseases (ASCVDs) and is commonly assessed through imaging modalities such as computed tomography (CT), X-rays, and Dual-energy X-ray Absorptiometry (DXA). Among these, lateral spine DXA scans, commonly used for osteoporosis screening, offer a cost-effective and low-radiation opportunity for opportunistic CVD risk …

Embodied Ai For Challenging Rearrangement Tasks In The Context Of Service And Assistive Robots, Mariia Khan

Theses: Doctorates and Masters

Embodied AI explores intelligent agents that learn through interaction with their environment, aiming to replicate human-like learning processes. Achieving this requires agents capable of understanding a scene via various sensors, reasoning about their actions, and reacting accordingly. These abilities are necessary for service domestic robots to assist humans in their day-to-day activities. Embodied AI tasks can include but are not limited to: visual exploration, visual navigation, instruction following and embodied question answering, which typically consider static (unchanging) environments, where objects do not move over time. This thesis addresses one of the most challenging Embodied AI tasks – visual room rearrangement, …

Applying Machine Learning And Optimization Algorithms To Perform Feature Selection, Shizhao Yu

Theses and Dissertations (Comprehensive)

The objective of feature selection in the realms of machine learning and data mining is integral, serving as an efficient mechanism to eradicate redundant or irrelevant features, and subsequently augmenting the performance of predictive models. In the contemporary landscape of big data, with the escalating dimensionality of datasets, the efficacy of traditional feature selection methodologies is compromised, due to their computational complexity and ineptitude in addressing the curse of dimensionality. This thesis posits a pioneering feature selection framework that amalgamates machine learning with advanced optimization algorithms. The methodology employs a Support Vector Machine (SVM), in conjunction with a cutting-edge metaheuristic …

Towards Human Explainable Digital Forensics: Generating Human Interpretable Evidence For Semantic Understanding In Manipulated Images And Text, Yuwei Chen

Electronic Theses & Dissertations (2024 - present)

Detecting and characterizing manipulations in digital media continues to pose a significant challenge within the field of digital forensics. Despite notable advancements, the discipline often remains in a reactive stance against emerging threats. Current state-of-the-art methods, typically evaluated within academic settings, fails to mirror the complexities of real-world disinformation scenarios. These methods generally prioritize high performance based on quantitative metrics, yet they demonstrate a considerable dependency on training data and lack adaptability to new novel attack signatures. With the rapid evolution of attack methodologies, the dependency on highly accurate models that do not generalize or adapt well to unseen threats …

Large Scale Machine Learning Over Knowledge Graphs, Bedirhan Gergin

Electronic Theses & Dissertations (2024 - present)

Knowledge graphs (KGs) have become popular across various fields, providing convenient access to web-based knowledge while storing and formalizing domain-specific information. By analyzing KGs, patterns, connections, and dependencies can be identified across different data sources, enabling the inference of new knowledge from given facts. As the use of KGs expands, the size of modern KGs has grown significantly, making them impossible to process within the main memory of a single computer. Distributed computing offers a viable solution to this challenge by leveraging the combined capabilities of multiple servers within a cluster. This thesis explores how distributed computing can be effectively …

Studies On Convexity Of Dnf Formulae, Josue A. Ruiz

Electronic Theses & Dissertations (2024 - present)

In this dissertation, we investigate the problem of determining whether a Boolean formula given in disjunctive normal form (DNF) is convex. Although Boolean formulas have various applications, our research focuses on the practical application for rule-based access control policies, where policies are often expressed as a set of Boolean rules. Understanding the structural properties of such formulas is crucial for determining whether a policy can be efficiently represented within a specific access control model.

The main contribution of this research is the conception and analysis of convexity derived from the “gap problem.” In this context, convexity is characterized by the …

Safeguard Cyberspace In Ransomware Era: Risk Analysis & Cyber Insurance, Li Huang

Electronic Theses & Dissertations (2024 - present)

The increasing frequency and severity of ransomware attacks pose significant challenges for organizational cybersecurity. Fragmentation across disciplines in cyber defense has created practical gaps in the development of the necessary capabilities needed to address rapidly evolving cyber threats. This study explores the impact of ransomware attacks and the evolving role of cyber insurance as a proactive cybersecurity partner. Bridging the gap between actuarial science and cyber risk management, it proposes an interdisciplinary framework that quantifies the impact of ransomware and integrates cyber insurance into cybersecurity strategies.

The primary contribution of this study is methodology. We present a framework that remains …

Improving Generalizability In Image Manipulation Detection, Zhenfei Zhang

Electronic Theses & Dissertations (2024 - present)

Image manipulation detection (IMD) aims to determine whether an image has been tampered with and to identify the manipulated regions. These capabilities have become increasingly important with the rapid advancement of media editing and generation technologies, such as Photoshop and generative AI methods, which underscore the need for robust tools for media authentication. Although current state-of-the-art (SoTA) methods achieve strong results on common manipulation types, such as splicing, copy-move, and removal, they often struggle to generalize to manipulation types not represented in the training data. Consequently, their real-world applicability remains limited, with performance degrading significantly in practical scenarios.

In this …

Securing Secrets: Exploring The Aes Encryption And Key Security Capabilities Of Chatgpt, Kayla Taylor

Student Works

The development and increasing accessibility of generative artificial intelligence (AI) tools and large language models (LLMs) have allowed cryptographers to explore a variety of cryptanalysis problems in dynamic and interactive ways. Prompt engineering, the process by which input text is tested and refined to elicit a desired response from LLMs, is a nascent area of research that remains largely unexplored in many contexts, including cryptography. This study will explore the potential applications and limitations of prompt engineering in the context of Advanced Encryption Standard (AES) encryption and key security with OpenAI’s ChatGPT (GPT-4o) through two main objectives: First, given a …

Analysis Of Bin Packing Variants, Kyle T. Ambrose

UNF Graduate Theses and Dissertations

The Bin Packing problem is a classic and widely studied optimization problem that arises naturally in applications like manufacturing, logistics, and memory allocation, where space and resource constraints are critical. In this thesis, we first demonstrate the NP-completeness of Bin Packing via a reduction from Three-Dimensional Matching, establishing its foundational complexity. We then survey core heuristics for the one-dimensional case and extend our analysis to two and three-dimensional variants, including both offline and online strategies. Special attention is given to stochastic bin packing, where item sizes are modeled as random variables drawn from distributions such as uniform, truncated normal, and …

Reinforcement Learning For Scheduling And Routing: Electric Vehicles Charging And Patrol Scheduling, Majid Ghasemi

Theses and Dissertations (Comprehensive)

This thesis offers a comprehensive exploration of Reinforcement Learning (RL), beginning with fundamental theoretical constructs, Markov Decision Processes, Dynamic Programming, Monte Carlo, and Temporal Difference methods, and extending into state-of-the-art deep RL approaches such as Deep Q-Networks (DQN) and policy-gradient algorithms. Through analytical experiments in controlled environments, the thesis demonstrates how distinct algorithmic choices (e.g., exploration techniques, eligibility traces, or network architectures) influence convergence and stability. These foundational insights pave the way for two in-depth case studies, which apply RL techniques to critical, real-world scheduling and routing challenges.

The first case study tackles the Electric Vehicle (EV) routing and charging …

Orchestrating Digital Technologies With Incumbent Enterprise Systems For Attaining Innovation, Sachithra Lokuge, Darshana D. Sedera, Varun Grover, Suprateek Sarker

Information Systems Faculty Publications and Presentations

In the late 1990s, most organizations adopted enterprise systems (ES) to automate their core business processes. The very same organizations are presented with a new wave of opportunities to innovate with digital technologies—technologies that purport to have diametrically opposed characteristics to ES. This study explores how organizations integrate digital technologies with their incumbent ES for attaining innovation. The study followed a qualitative approach and gathered data from four organizations consisting of six such projects. By applying a unique theoretical foundation, this study derives interesting insights into the orchestration process of ES and digital technologies for attaining innovation.

Ai And Tribal Court Practice, Matthew L.M. Fletcher

Articles

American Indian tribal court practice resides at the intersection of two difficult legal problems. First, because tribal justice systems are usually very young and dynamic, awareness and analysis of tribal law is underdeveloped. Second, because tribal nations are not governed by state or federal law, tribal law is culturally unique. Tribal court practitioners often find that even routine legal matters will involve questions of first impression in the jurisdiction. All of this is to say tribal court jurisprudence is intensely jurisgenerative.

Because tribal law is often unsettled or indeterminate, the costs of discovering and applying this law are occasionally high. …

Environment Scan Of Generative Ai Infrastructure For Clinical And Translational Science, Hua Xu, Jiang Bian, Chunhua Weng, Yifan Peng, Betina Idnay, Zihan Xu, William G. Adams, Mohammad Adibuzzaman, Nicholas R. Anderson, Neil Bahroos, Douglas S. Bell, Cody Bumgardner, Thomas Campion, Mario Castro, James J. Cimino, I. Glenn Cohen, David Dorr, Peter L. Elkin, Jungwei W. Fan, Todd Ferris, David J. Foran, David Hanauer, Mike Hogarth, Kun Huang, Jayashree Kalpathy-Cramer, Manoj Kandpal, Niranjan S. Karnik, Avnish Katoch, Albert M. Lai, Christophe G. Lambert, Lang Li, Christopher Lindsell, Jinze Liu, Zhiyong Lu, Yuan Luo, Peter Mcgarvey, Eneida A. Mendonca, Parsa Mirhaji, Shawn Murphy, John D. Osborne, Ioannis C. Paschalidis, Paul A. Harris, Fred Prior, Nicholas J. Shaheen, Nawar Shara, Ida Sim, Umberto Tachinardi, Lemuel R. Waitman, Rosalind J. Wright, Adrian H. Zai, Kai Zheng, Sandra Soo-Jin Lee, Bradley A. Malin, Karthik Natarajan, Nicholson Price, Rui Zhang, Yiye Zhang

Articles

This study reports a comprehensive environmental scan of the generative AI (GenAI) infrastructure in the national network for clinical and translational science across 36 institutions supported by the CTSA Program led by the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health (NIH) at the United States. Key findings indicate a diverse range of institutional strategies, with most organizations in the experimental phase of GenAI deployment. The results underscore the need for a more coordinated approach to GenAI governance, emphasizing collaboration among senior leaders, clinicians, information technology staff, and researchers. Our analysis reveals that 53% of …

Clinicians In The Loop Of Medical Ai, W. Nicholson Price Ii

Articles

As medical AI begins to mature as a health-care tool, the task of governance grows increasingly important. Ensuring that medical AI works, works where it’s used, and works for the patient in the moment is a challenging, multifaceted task. Some of this governance can be centralized—in review by FDA or by national accreditation labs, for instance. Some must be local, performed by the hospital or health system about to use the product in their own, unique environment. But a large amount of governance is left to the individual provider in the room, the human in the loop who presumably knows …

Do Specialized Medical Llms Demand A Radically New Approach Under The Eu's Medical Device Regulation, Hannah Louise Smith, W. Nicholson Price Ii

Articles

We examine the arguments made by Onitiu and colleagues concerning the need to adopt a “backward-walking logic” to manage the risks arising from the use of Large Language Models (LLMs) adapted for a medical purpose. We examine what lessons can be learned from existing multi-use technologies and applied to specialized LLMs, notwithstanding their novelty, and explore the appropriate respective roles of device providers and regulators within the ecosystem of technological oversight.

Boden Lecture: Taxation Of Autonomous Artificial Intelligence, Reuven S. Avi-Yonah, Lucas Brasil Salama, Herbert Snitz, W. Robert Thomas

Articles

This Article proposes that tax can be a useful supplement to other measures to regulate Autonomous Artificial Intelligence (AAI) and limit its potential harmful effects. This proposal differs from command-and-control regulation of AAI along the lines of European Union legislation that may unduly limit the development of AAI. It also differs from existing proposals to tax AAI to generate revenue to help workers displaced by AAI programs, or to tax the data used by AAI The proposal is based on granting AAI programs like ChatGPT separate legal personhood, like corporate personhood, while incentivizing or requiring their corporate owner to place …

Synthetic Data Generation Of Health And Demographic Surveillance Systems Data: A Case Study In A Low- And Middle-Income Country, Dorcas G. Mwigereri, Nigel T. Kamotho, Akbar K. Waljee, Ryan T. Rego, Eileen M. Weinheimer-Haus, Farhana Alarakhiya, Anthony K. Ngugi, W. Nicholson Price, Ji Zhu, Stephen Peter Wong, Geoffrey H. Siwo

Articles

Objective: To evaluate effectiveness of open-source generative models in producing high-quality tabular synthetic data using a Health and Demographic Surveillance System (HDSS) dataset from rural Kenya, as a proof of concept in a low- and middle-income (LMIC) setting.

Materials and Methods: Three open-source models (CTGAN, TableGAN, and CopulaGAN) were used to generate synthetic data from the Kaloleni/ Rabai HDSS dataset. To assess the quality of the synthetic datasets generated by each model, we performed fidelity, utility, and privacy tests.

Results: CTGAN outperformed the other models, producing synthetic data that closely mirrored the statistical properties of the real dataset while preserving …

The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, W. Nicholson Price Ii, Arti Rai

Articles

As artificial intelligence (AI) transforms drug development, regulatory frameworks are evolving to oversee its implementation, particularly at the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This paper makes three contributions to understanding emerging regulatory approaches. First, we offer a comparative analysis of how these agencies have responded to AI-driven advances, incorporating new US executive orders and the European Union (EU)’s AI Act. Second, we propose a novel analytical framework to understand regulatory divergence: the FDA’s flexible, dialog-driven model contrasts with the EMA’s structured, risk-tiered approach, reflecting broader institutional and political-economic differences. While the former encourages …

Neural And Computational Approach To Understanding Environmental Modulation Of Behavioral Identity In Zebrafish, John W. Hageter

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organisms rely on behavior for survival. Animals engage in behaviors that allow for feeding, mating, exploring and navigating their environment among others. Necessary for these behaviors to develop are the environmental factors and underlying circuitry which make behavior possible. Specifically, how the environment guides underlying neural circuitry to develop unique facets or phenotypes of a larger behavior are key to understanding why unique behaviors exist. In this thesis, I build foundational evidence for determining these mechanisms through the use of the zebrafish local search behavior. This is a behavior that zebrafish employ following the loss of environmental illumination where they …

Development And Application Of Computational Tools For Data-Driven Materials Science., Logan L. Lang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Modern materials science generates vast amounts of data from computational simulations and experiments, creating significant challenges for data processing and analysis. This thesis addresses these challenges through the development and application of computational tools within the framework of Material Data Science (MDS). Contributions span the four pillars of MDS: Material/Molecular Data, Algorithms, Databases, and High-Throughput Processes—with a primary focus on the Algorithm, Data, Database pillars.

For the Algorithm pillar, two Python libraries were developed to streamline common analysis tasks. PyProcar simplifies the post-processing and visualization of electronic structure data (band structures, density of states, Fermi surfaces) obtained from various Density …

Using Visual Prompts To Analyze Ejection Fraction In Echocardiograms, Kevin Reisch

Graduate Theses, Dissertations, and Problem Reports (ETD)

Left ventricular ejection fraction (LVEF) is a critical biomarker for heart failure, but manual estimation from echocardiograms is time-consuming. Artificial intelligence can be used to accelerate this process, allowing clinicians to focus on other critical tasks. Current methods typically train models from scratch on echocardiogram datasets; however, this approach is limited by the scarcity of large medical imaging datasets, which are expensive and difficult to acquire. We present a transfer learning approach that leverages pretrained models from massive datasets, enabling continuous improvement as foundation models advance. Our method employs visual prompting to generate trainable masks for echocardiogram videos, transforming the …

The Effect Of Facial Phenotypes On Differential Performance Of Facial Recognition, Evan R. Garrett

Graduate Theses, Dissertations, and Problem Reports (ETD)

Facial recognition technology is utilized in many facets of life. As the use has become more widespread these systems have improved in reliability and performance approaching the level of human accuracy. With these improvements the problem of bias still remains as a persistent problem. Efforts have been made to minimize the bias prevalent in the systems via studies into various demographic factors, creating training datasets that have a more uniform distribution of subjects, and other methods. As facial recognition is one of the most utilized forms of biometric recognition it is vital to analyze potential causes of bias to help …

Simulation Of Annpet For Neural Network Training And System Performance Benchmarking, Pete Martone

Graduate Theses, Dissertations, and Problem Reports (ETD)

Monte Carlo (MC) simulations are often used to provide insight into complex physical phenomenon. They can generate realistic results without the necessity to construct costly and complex apparatus. The ultimate value of these simulations depend on how accurately the physics can be modeled and if a sufficient volume can be produced to account for statistical variance. In medical imaging device development, MC simulations of Positron Emission Tomography (PET) scanners have typically been used to model the performance of new systems. The imaging group in the Department of Radiology have developed a unique detector design for a pre- clinical PET scanner …

Applications Of Deep Learning For Optimizing Fingerphoto And Latent Fingerprint Biometrics, Amol Sanjay Joshi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fingerprint-based biometric recognition remains one of the most dependable and widely adopted approaches for identity verification due to its permanence and distinctiveness. Recent advancements in mobile and contactless imaging have extended fingerprint acquisition beyond controlled environments into unconstrained, real-world conditions through fingerphotos, contactless fingerprint images captured by digital or smartphone cameras. While this paradigm shift enhances accessibility and user convenience, it introduces significant technical challenges. Variations in illumination, focus, and motion blur often degrade ridge patterns, making accurate feature extraction and matching more difficult. Similarly, in forensic applications, latent fingerprints, incomplete or smudged prints lifted from surfaces, pose unique challenges …

Individual And Collective Properties Of Tunable Photochemical Belousov-Zhabotinsky Micro-Reactors, Kudakwashe Benedict Shumba

Graduate Theses, Dissertations, and Problem Reports (ETD)

Cell-like model chemical systems are powerful tools that can be used to explore the role of intercellular coupling on population level behaviors in communities of biological cells. Firstly, we present a new method for fabricating such micro-reactors using the photosensitive Belousov–Zhabotinsky (BZ) reaction system employed in silica microparticles. These BZ micro-reactors have a tunable response to photochemical coupling, varying from a fully excitatory response to a fully inhibitory response. Their response can be tuned through variations in either the reactive mixture or, on an individual micro-reactor level, by changes in the synthesis temperature used during the fabrication of the silica …

Toward Privacy-Preserving Data Sharing - An Australian Healthcare Perspective, Kimley Foster, Nectarios Costadopoulos, Arash Mahboubi, Sabih Ur Rehman, Md Zahidul Islam

Research outputs 2022 to 2026

The rise of big data has brought increased urgency to the importance of privacy-preserving data sharing in healthcare. In Australia, health records exist in various databases; however data sharing is limited. While many consumers and healthcare professionals recognise the advantages of sharing data for research and health care services, misgivings about privacy and security persist. This study examined current perspectives on data sharing, investigating the trust level in privacy preserving data sharing tools and techniques among healthcare professionals and organisations, and their openness to adopting technology for secure data sharing. We incorporated participants from various healthcare professions across Australia. We …

Protocol For An Integrative Meta-Analysis Of The Application Of Machine Learning Algorithms In The Prediction Of Chronic Disease Risks And Outcomes, Ebenezer Afrifa-Yamoah, Emmanuel Peprah-Yamoah, Enoch Odame Anto, Victor Opoku-Yamoah, Eric Adua

Research outputs 2022 to 2026

Background: Precise risk prediction of chronic diseases is essential for effective preventive care and management. Machine learning (ML) is a promising avenue to enhance chronic disease risk prediction; however, a comprehensive assessment of ML performance across various chronic diseases, populations, and health settings is needed. Methods: This meta-analysis aims to synthesize evidence on the performance of ML techniques for predicting the risks and outcomes of chronic diseases. A literature search was conducted through PubMed, Web of Science, Scopus, Science Direct, Medline, and Embase. Studies applying ML techniques to predict chronic disease risks or outcomes and reporting performance metrics were included. …

Zero Day Ransomware Detection With Pulse: Function Classification With Transformer Models And Assembly Language, Matthew Gaber, Mohiuddin Ahmed, Helge Janicke

Research outputs 2022 to 2026

Finding automated AI techniques to proactively defend against malware has become increasingly critical. The ability of an AI model to correctly classify novel malware is dependent on the quality of the features it is trained with and the authenticity of the features is dependent on the analysis tool. Peekaboo, a Dynamic Binary Instrumentation tool defeats evasive malware to capture its genuine behaviour. The ransomware Assembly instructions captured by Peekaboo, follow Zipf's law, a principle also observed in natural languages, indicating Transformer models are particularly well-suited to binary classification. We propose Pulse, a novel framework for zero day ransomware detection with …

Genai’S Impact On Global It Management: A Multi-Expert Perspective And Research Agenda, Yogesh K. Dwivedi, Laurie Hughes, Mohammad S. Al-Ahmadi, Vincent Dutot, Syed Q. Ahmed, Shahriar Akter, Rahul De’, Keyao Li, Nitish Singh, Paul Walton

Research outputs 2022 to 2026

Generative AI (GenAI) is disrupting global IT management and challenging established practice. The increasing use of GenAI technology is redefining localization, transforming existing workforce roles, outsourcing strategy, and team dynamics. Simultaneously, GenAI’s security complexities have prompted the rethinking of existing risk frameworks to meet a new set of challenges from GenAI enhanced cyber threats. This article explores these complex and converging factors, providing a roadmap to address GenAI’s significant impact on global IT management. We advocate the responsible adoption of GenAI and importance of building resilient, value-driven, globally consistent IT ecosystems able to adapt to the significant challenges and opportunities …