Osteopathic Medicine and Osteopathy Commons^™

Nefom: Board Of Trustees: Corporation Members, New England Foundation For Osteopathic Medicine

William Kirmes, D.O. Collection

List of NEFOM corporation members, undated.

New England Osteopathic Assembly: Maxwell To Kirmes, R. E. Maxwell D.O.

William Kirmes, D.O. Collection

A short handwritten personal note from Dr. R.E. Maxwell to Dr. Kirmes arranging their trip to the New England Osteopathic Assembly meeting.

New Hampshire Osteopathic Association: Dr. Kirmes To Potential New Hampshire D.O.S, William Kirmes D.O.

William Kirmes, D.O. Collection

A letter from Dr. Kirmes to potential New Hampshire D.O.s recommending coming to New Hampshire to practice.

Vermont Osteopathic Association: Address Regarding Basic Science Bill, Unknown

John McPartland, D.O. Collection

An address given by a member of the Vermont Osteopathic Association regarding the Vermont State Basic Science Bill.

January 2023, New England Osteopathic Heritage Center

New England Osteopathic Heritage Center Newsletter

New England Osteopathic Heritage Center's annual newsletter for January 2023

Nefom: What Is An Osteopathic Physician Anyway?, New England Foundation For Osteopathic Medicine

William Kirmes, D.O. Collection

A pamphlet entitled "What is an Osteopathic Physician Anyway?"

The Efficacy Of Prp Injection Vs Corticosteroid Injection In The Management Of Common Tendinopathies: A Systematic Review, Eric Caloud

Theses and Graduate Projects

Background: Tendinopathy is one of the most prevalent musculoskeletal disorders in active patients, accounting for at least 7% of physician visits in the United States. In recent years, there has been an increasing body of evidence for the use of platelet-rich plasma (PRP) in the management of tendinopathies compared to corticosteroid injections (CSI) for patients refractory to conservative treatment.

Methods: This review was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The SPORTDiscus, PubMed, and Google Scholar databases were searched for randomized controlled studies published between 2010 and 2023. The keywords utilized in the …

2023‐2024 Student Research Fellowship Recipients, University Of New England College Of Osteopathic Medicine

Peter Morgane Research Fellowships

2023-2024 recipients of the University of New England College of Osteopathic Medicine's Peter Morgane Research Fellowship.

Sexually-Divergent Differentiation And Inflammatory Response To Osteoclasts, Lilijanna L. Cummings

EWU Masters Thesis Collection

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (2023, No. 1), Philadelphia College Of Osteopathic Medicine

PCOM Digest 2020s

The 2023 Vol. 1 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Updates
• Advancing Alumni
• Institutional Heritage: Founders’ Day 2023
• Digest Magazine Anniversary Series: 125 Years Through 125 Stories
• The Longest-Tenured Dean: Kenneth J. Veit, DO ’76, MBA, FACOFP, reflects on his historic distinction
• This Old House: The story of the Tudor Revival-style mansion that was renovated to become an administration building at the heart of the PCOM campus in Philadelphia
• Class Notes

Osteoblast-Specific Overexpression Of Nucleolar Protein No66/Riox1 In Mouse Embryos Leads To Osteoporosis In Adult Mice, Qin Chen, Krishna M Sinha, Benoit De Crombrugghe, Ralf Krahe

Faculty, Staff and Student Publications

In previous study, we showed that nucleolar protein 66 (NO66) is a chromatin modifier and negatively regulates Osterix activity as well as mesenchymal progenitor differentiation. Genetic ablation of the NO66 (RIOX1) gene in cells of the Prx1-expressing mesenchymal lineage leads to acceleration of osteochondrogenic differentiation and a larger skeleton in adult mice, whereas mesenchyme-specific overexpression of NO66 inhibits osteochondrogenesis resulting in dwarfism and osteopenia. However, the impact of NO66 overexpression in cells of the osteoblast lineage in vivo remains largely undefined. Here, we generated osteoblast-specific transgenic mice overexpressing a FLAG-tagged NO66 transgene driven by the …

Effect Of Stretch And Release On Myofascial Stem Cell Function In Vitro: A Putative Model To Understand The Molecular Benefits Of The Myofascial Release (Mfr) Technique, Ben Smith, Shahn Notta, Debasis Mondal

Research Day

Despite the beneficial effects of osteopathic manipulative techniques (OMT), there is a lack of in vitro models to understand the molecular mechanisms associated with these time-tested therapies. The Myofascial Release (MFR) technique is a non-invasive approach that involves passive stretching, hold and release, of the soft tissue to achieve myofascial homeostasis. Tissue-resident mesenchymal stem cells (MSC) can regulate the myofascial microenvironment by altering their secreted factors following stretch and release. Therefore, we initiated studies to develop an in vitro model to investigate the possible effects of stretch and release on MSC function, i.e. proliferation and differentiation capabilities, and changes in …

The Effects Of Sex On Zebrafish Bone Metabolism, Simon Bagatto

Williams Honors College, Honors Research Projects

I investigated the effects of diet and sex on zebrafish bone metabolism. Zebrafish were subjected to either a high-calorie or low-calorie diet over a five-week period. After this diet, zebrafish scales were used to measure alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP) enzyme activity with a fluorescent substrate. The enzyme activities were markers of the osteoblasts (ALP) and the osteoclasts (TRAP). These data were compared among sex and diet of the zebrafish using a repeated measures ANOVA statistical test. I also measured the number of resorption lacunae per scale (another indicator of osteoclast activity). The results showed higher TRAP …

Utilizing The Zebrafish Species, Danio Rerio, To Assess The Effect Of Acute Treatment With St. John’S Wort Supplements On Anxiety As Measured By The Novel Dive Tank Test, Sebastian Woodson, Lori Mcgrew Dr.

Research Projects

Background: The zebrafish species, Danio rerio, is a widely utilized model organism with well-characterized behaviors including anxiety-like behavior when placed into a novel environment. In addition, the fish can be treated with substances by immersion.

St. John’s Wort has been suggested as a plant-based treatment for depression and anxiety because it contains compounds that inhibit the serotonin transporter (SERT) among other effects. A number of St. John’s Wort supplements are commercially available.

The National Institute of Mental Health (NIMH) estimates that about 19% of US adults suffer an anxiety disorder each year and about 31% will experience an anxiety disorder …

Pcom Physician Assistant Class Of 2024 White Coat Ceremony, Philadelphia College Of Osteopathic Medicine

White Coat Ceremony

Program of PCOM Philadelphia Campus 2022 Physician Assistant White Coat Ceremony Program for the Class of 2024.

Remarks from PCOM PA Alumnus: Jenny Boyce, MS, PA-C.

Using The Articularis Genu To Test Peri-Articular Muscle Health During Knee Osteoarthritis, José A. Cruz Ayala, Mallory Crawford, Mary C. Gatterer, Maria Tovar, Jessica C. Rivera, Vinod Dasa, Luis Marrero

School of Medicine Faculty Publications

Knee osteoarthritis (OA) involves peri-articular sarcopenia. The infrapatellar articularis genu (AG) links to the quadriceps femoris (QF) and can be sampled from discarded tissue during arthroplasty. We predict disuse-mediated changes in AG myofiber type ratio and atrophy similar to reports on the QF during OA. OA AGs (n = 40) were preserved and grouped by poor (≤ 85°; n = 11), fair (90°–110°; n = 19), and good (≥ 115°; n = 10) range of motion (ROM). Immunolabeling of slow and fast myosin heavy chains in AG sections allowed comparing distribution and cross-sectional area (CSA) of type-I (T1) and type-II …

Mice Lacking Wnt9a Or Wnt4 Are Prone To Develop Spontaneous Osteoarthritis With Age And Display Alteration In Either The Trabecular Or Cortical Bone Compartment, Stefan Teufel, Lena Wolff, Ulrich König, Akio Kobayashi, Richard Behringer, Christine Hartmann

Faculty, Staff and Student Publications

Osteoarthritis (OA) is a common degenerative disease of the joint, with a complex multifactorial not yet fully understood etiology. Over the past years, the Wnt signaling pathway has been implicated in osteoarthritis. In a recent genomewide association study (GWAS), the chromosomal location on chromosome 1, linked to the Wnt3a-Wnt9a gene locus, was identified as the most significant locus associated with a thumb osteoarthritis endophenotype. Previously, it was shown that WNT9a is involved in maintaining synovial cell identity in the elbow joint during embryogenesis. Here, we report that the conditional loss of Wnt9a in the Prx1-Cre expressing limb mesenchyme or Prg4-CreER …

Commencement, Philadelphia (2022), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus D.O. Commencement program, Class of 2022. Degrees include Doctorate in Osteopathic Medicine

Commencement, Georgia (2022), Philadelphia College Of Osteopathic Medicine

Commencements

Georgia Campus Commencement program, Class of 2022. Degrees include Doctorate in Osteopathic Medicine, Doctorate in Pharmacy, and Doctorate in Physical Therapy.

Comparative Assessment Of Grit In The Allopathic Versus Osteopathic Physician, Amber Cheesman, Meagan Vermeulen, Joanna Petrides, Charalampos Papachristou

Rowan-Virtua Research Day

Matriculating into medical school is a strenuous process, including numerous roadblocks unique to both allopathic and osteopathic schools, with osteopathic applicants often jumping more hurdles in the journey.

Grit: passion and perseverance towards long term goals, especially in the setting of failure/adversity

High levels of grit correlate with low levels of burnout

Purpose: examine grit in allopathic versus osteopathic physician to help identify resources to prevent physician burnout

The Effects Of The Covid-19 Stay-At-Home Orders On Pain And Mental Health In Omm Patients, Sylvia Orozco Silberman, Philip Collins, Danielle Cooley, James Bailey, Steven M. Brunwasser, Nicholas Averell

Rowan-Virtua Research Day

New Jersey was placed in a state of emergency and a statewide stay-at-home order during the COVID-19 pandemic

Very little has been published examining the effects of chronic pain after stopping osteopathic manipulative medicine (OMM), although it seems unethical to stop a treatment shown to work so well that is both minimally invasive and cost effective

We hypothesized OMM patients experienced an increase in pain since the onset of COVID-19 pandemic and closure of OMM/Family Medicine offices

Use Of Osteopathic Manipulative Treatment In Alleviating Hypertonic Chest Wall Pain, David Ho, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

We present the case of a 20-year-old male patient with no cardiac history coming in for left sided chest pain described as “burning” sensation. On physical exam, it was noted that patient had hypertonic chest wall muscles that were tight and spastic when palpated on the left chest wall. We used Osteopathic Manipulative Treatment (OMT) to help patient relieve hypertonic muscle. We chose to use muscle energy technique (MET) since this relies on reciprocal inhibition with the end result being relaxation of the target muscle.

The patient had resolution of chest pain after applying the technique. Although we did not …

A Review Of The Effectiveness Of Osteopathic Manipulative Medicine At Alleviating Pregnancy-Related Pain, Alexandria Lomanno, Olivia Choi, Danielle Cooley

Rowan-Virtua Research Day

Globally, more than a quarter of pregnant patients experience low back pain (LBP) during pregnancy with additional complaints of pelvic girdle pain (PGP) and other somatic dysfunctions. Though the standard of care for LBP in pregnancy is often analgesics, concerns about potential side effects that may cause lasting harm to the fetus may preclude pregnant patients from taking pain medications. Osteopathic Manipulative Medicine (OMM) is a nonpharmacologic treatment option that is routinely used for LBP in non-pregnant patients. Given the low risk of adverse effects, OMM may prove to be beneficial for pregnant patients suffering from LBP or PGP.

Use Of Pocus And Omt For Anterior Shoulder Reduction, David Ho, James Espinosa, Alan Lucerna, Neeharika Bhatnagar

Rowan-Virtua Research Day

Shoulder dislocations are very a common presentation in the emergency department. This represents about 50% of all joint dislocations presenting to the ER. Over 95% of the dislocations are anterior. Approximately 70% of shoulder dislocations occur in men and in both genders, the prevalence of shoulder dislocations occurs in a bimodal distribution in age in those younger than 20 and over 60 years old. Shoulder dislocation can occur anteriorly, posteriorly, and inferiorly. In an anterior dislocation, excessive force from external rotation and abduction causes a tear in the anterior ligamentous capsule3, causing the humeral head to dislocate from the glenoid …

Comparing The Relapse Rate Between Medication Assisted-Only Treatment And Medication-Assisted Treatment With An Osteopathic Manipulative Treatment Regimen In Patients With Musculoskeletal Pain, Karen Huang, Danielle Cooley

Rowan-Virtua Research Day

Since the opioid crisis first began in 1991, opioid-related overdoses in the United States have continued to increase dramatically, killing nearly 47,000 people in 2018, and making it one of the most pressing issues in healthcare. The most reported reason for misuse of pain relievers was to relieve physical pain. The increase in opioid abuse has also led to an increase in patients seeking medication-assisted treatment (MAT).

Osteopathic manipulative treatment (OMT) has been shown to have efficacy in relieving both chronic and acute pain. No current studies have investigated the use of OMT as an adjunct treatment to MAT for …

Omm As A Complementary Therapy For Chronic Shoulder Overuse Injury In A Division Iii Softball Pitcher, Drew Saltzman, Ruchir Nanavati, Taylor Parsons, Seungkyu Park, David Abend

Rowan-Virtua Research Day

At the height of the season, baseball and softball pitchers are playing 4-5 games a week and practicing on days without games. As a result, they put tremendous additive stress on their throwing shoulder and elbow joint.

This case utilized a novel, non-invasive osteopathic approach to improving shoulder mobility in a Division III athlete. If used on a regular basis, the shoulder mobility technique shows utility for athletes suffering from overuse injury. Our patient showed mild qualitative improvement, however they continue to use OMM as complementary treatment and describe a moderate qualitative improvement.

Effect Of Osteopathic Manipulative Treatment In Patients With Postural Orthostatic Tachycardia Syndrome (Pots): A Literature Review, Sidharth Sahni, Harrison Jordan, Binoy Desai, Danielle Cooley, Alexander King

Rowan-Virtua Research Day

Postural Orthostatic Tachycardia Syndrome (POTS) is characterized by autonomic dysregulation resulting in diminished blood flow and excessive tachycardia.

POTS has been scarcely studied in the clinical setting. A review of literature generated only four articles, only one of which met the established criteria.

A follow up study to evaluate the effect of OMT on the quality of life for patients with POTS is planned. The hypothesis is that osteopathic manipulation plays a role in the management of POTS, as patients should experience improvement in their symptoms and their overall quality of life.

The History Principles And Purpose Of The Academy Of Applied Osteopathy, Academy Of Applied Osteopathy

Stanley Kimball, D.O. Collection

Academy of Applied Osteopathy brochure detailing the history, objectives, platform, future, finance, and membership information for the organization.

Working Paper For Proposed New England College Of Osteopathic Medicine, New England Foundation For Osteopathic Medicine

Stanley Kimball, D.O. Collection

The Working Paper for Proposed New England College of Osteopathic Medicine describes plans for the creation and structure of a new college of Osteopathic Medicine created by the New England Foundation for Osteopathic Medicine.

Osteopathy And The Profession Of Medicine, Anna G. Tinkham D.O.

Stanley Kimball, D.O. Collection

Letter written to the Atlantic monthly in response to an article critical of osteopathy written by Dr. Channing Frothingham.