Osteopathic Medicine and Osteopathy Commons^™

A Review Of The Literature On The Utilization Of Stem Cells In Knee Osteoarthritis, Katrina Krist

Theses and Graduate Projects

Background: This literature review evaluates the utilization of various types of stem cells in the treatment of osteoarthritis.

Purpose: To assess the different types of stem cell therapy available in an attempt to determine its effectiveness and viability as a long term therapy option.

Methods: Articles were found by searching Augsburg Library Services, Google Scholar, and PubMed for recent, original studies using both allogeneic or autologous stem cells from a variety of cell lines including bone marrow and adipose tissue.

Conclusions: The utilization of stem cells as a viable treatment option for osteoarthritis shows improvement in pain management and return …

The Efficacy Of Prp Injection Vs Corticosteroid Injection In The Management Of Common Tendinopathies: A Systematic Review, Eric Caloud

Theses and Graduate Projects

Background: Tendinopathy is one of the most prevalent musculoskeletal disorders in active patients, accounting for at least 7% of physician visits in the United States. In recent years, there has been an increasing body of evidence for the use of platelet-rich plasma (PRP) in the management of tendinopathies compared to corticosteroid injections (CSI) for patients refractory to conservative treatment.

Methods: This review was performed in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The SPORTDiscus, PubMed, and Google Scholar databases were searched for randomized controlled studies published between 2010 and 2023. The keywords utilized in the …

Comparing Efficacy Of Denosumab To Bisphosphonates In Fragility Fractures, Ronald Toledo Cardoso

Theses and Graduate Projects

Background: Osteoporosis is a disease of the bones with decreased bone mineral density and bone mass, leading to poor bone quality/structure, increasing the risk of fragility fractures. Pharmacological treatment is recommended to decrease risk of fractures. Current first line treatment is with bisphosphonates; however, alternative treatment includes denosumab. Both bisphosphonates and denosumab are antiresorptive drugs but differ in mechanism of action. Bisphosphonates remain as first line treatment.

Purpose: The purpose of this literature review is aimed at the PICO question in adults with osteoporosis, what is the efficacy of denosumab compared to bisphosphonates in decreasing the risk of …