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Full-Text Articles in Medical Specialties

Venlafaxine Exposure In Pregnancy And Its Association With Pre-Eclampsia Development, Jhanvi Patel May 2025

Venlafaxine Exposure In Pregnancy And Its Association With Pre-Eclampsia Development, Jhanvi Patel

Posters

Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), is widely used to manage depression and anxiety, including in pregnant women. However, its known hypertensive side effects raise concerns about a potential link to pre-eclampsia, a serious pregnancy complication characterized by new-onset hypertension and proteinuria. Pregnant women with psychiatric disorders already have an increased risk of hypertensive disorders, and while untreated depression can lead to adverse outcomes such as preterm birth and fetal cortisol elevation, the safety of venlafaxine remains uncertain. Current research lacks wellcontrolled studies assessing its association with hypertensive complications in pregnancy. This systematic review aims to evaluate whether venlafaxine use …


Safety And Utility Of Robotics In Pediatric Surgery: Implementation, Luke J. Man, Kristin Lemarbe, Nathan Novotny, Anthony Stallion, Begum Akay, Pavan Brahmamdam May 2025

Safety And Utility Of Robotics In Pediatric Surgery: Implementation, Luke J. Man, Kristin Lemarbe, Nathan Novotny, Anthony Stallion, Begum Akay, Pavan Brahmamdam

Posters

• Minimally invasive laparoscopic surgery is considered standard of care for adult and pediatric patients .

• Robotic surgery (RS) for adult patients has been widely adopted due to superior ergonomics, visualization, depth perception, and access to deeper anatomical structures2,3.

• Historically, RS is associated with longer operative times, higher cost, and lacks haptic feedback1,2.

• RS has had inconsistent adoption in the pediatric surgery community2.


Impact Of Michigan Public Act 246 On Opioid Prescribing For Pediatric Surgical Patients, Madison Saunders, Pavan Brahmamdam May 2025

Impact Of Michigan Public Act 246 On Opioid Prescribing For Pediatric Surgical Patients, Madison Saunders, Pavan Brahmamdam

Posters

1. Opioid misuse is an epidemic in the U.S. affecting 3.1% of pediatric patients.2,3.

2. Most common way adolescence obtain access to opioids is by their own prescription or a family member. 3,4 3.

3. In December 2017, Michigan enacted Public Act 246 (P246) in an attempt to address rising opioid misuse.

4. P246 states that as of June 1, 2018, a prescriber of a controlled substance must discuss the risks of opioid usage minor and the minor’s parent or guardian and sign a consent form.


Comparing Spatiotemporal Gait Measures And Hip Disability And Osteoarthritis Outcome Scores-12 Through Gait Analysis Of Individuals With Hip Osteoarthritis, Collin N. Thompson May 2025

Comparing Spatiotemporal Gait Measures And Hip Disability And Osteoarthritis Outcome Scores-12 Through Gait Analysis Of Individuals With Hip Osteoarthritis, Collin N. Thompson

Biological Sciences Undergraduate Honors Theses

Hip osteoarthritis (OA) is a joint disease that leads to degenerative damage surrounding the femoroacetabular joint, which can manifest as degraded cartilage and increased inflammation at the joint site. There are several methods physician’s use to measure a patient's condition, and our study looks at one called the Hip Disability and Osteoarthritis Outcome Score-12, or HOOS-12. This is a patient-reported outcome measure where patients can self-report their pain and level of dysfunction in relation to their hip osteoarthritis. This study investigates the association between the participants’ HOOS-12 scores and objective gait characteristics measured via a portable pressure sensing walkway. At …


A Retrospective Pilot Study Assessing The Concordance Between Referral Diagnoses, Referring Physician Specialty, And Emg/Ncv Results, Bodrul Islam, Daniel L. Menkes May 2025

A Retrospective Pilot Study Assessing The Concordance Between Referral Diagnoses, Referring Physician Specialty, And Emg/Ncv Results, Bodrul Islam, Daniel L. Menkes

Posters

  • Electromyoneurography (EMG/NCV) combines nerve conduction studies and needle electromyography.1 Patients are referred with a diagnostic hypothesis to be tested.
  • Nerve conduction studies assess large myelinated fibers, and needle EMG evaluates type I muscle fibers. Conditions affecting small fibers (e.g., neuropathic pain) or type II fibers (e.g., steroid myopathy) typically yield normal results, limiting the utility of EMG/NCV for their evaluation.1,2,3
  • Moreover, many patients are referred for EMG/NCV testing for nonspecific symptoms such as pain or numbness, often without objective neurological deficits.
  • This study was conducted to determine the concordance of the EMG referral with the provider’s specialty and the final …


Safety Profile Of Spinal Cord Stimulator Paddle Lead Revision And Replacement, Saini Kethireddy, Michael Staudt May 2025

Safety Profile Of Spinal Cord Stimulator Paddle Lead Revision And Replacement, Saini Kethireddy, Michael Staudt

Posters

  • Spinal cord stimulation (SCS) is a neuromodulatory treatment for patients experiencing chronic pain resistant to conservative therapies. It is often used for postlaminectomy syndrome, complex regional pain syndrome, and neuropathic pain.
  • SCS leads can be categorized into percutaneous leads and paddle leads, the latter requiring a laminectomy for implantation.
  • The advantages of paddle leads include lower migration rates and more efficient energy delivery.
  • Revision surgery may be required in instances of lead failure, migration or misplacement. Paddle lead replacement can be challenging due to extensive scar tissue formation, often requiring additional dissection.
  • Reoperation for paddle leads has raised concerns about …


Advances In Minimally Invasive Hepatobiliary Interventions For Non-Operative Candidates, Tulasi Talluri, Philip Cieplinski, Kristian Loveridge May 2025

Advances In Minimally Invasive Hepatobiliary Interventions For Non-Operative Candidates, Tulasi Talluri, Philip Cieplinski, Kristian Loveridge

Posters

Cholangioscopy is a technique used for diagnosing and treating patients with pathologies of the gallbladder, liver, and pancreas. It has been available since 1976 but with limited use in interventional radiology (IR) due to issues with steerability, irrigation capabilities, requirement for more than one operator, and poor percutaneous access options; however, direct intraluminal visualization of the gallbladder, common bile ducts, and even the ampulla and duodenum has become more practical with the advent of single operator percutaneous systems. Access to the biliary system can now be made through smaller 11 French sheath/delivery systems allowing for improved maneuverability into the common …


Comparison Of Two Adjuvant High-Dose Rate Vaginal Cuff Brachytherapy Dose Fractionation Regimens For Treatment Of Early-Stage Uterine Cancer, Catherine Raciti, Hong Ye, Allison J. Hazy, Maha Saada Jawad May 2025

Comparison Of Two Adjuvant High-Dose Rate Vaginal Cuff Brachytherapy Dose Fractionation Regimens For Treatment Of Early-Stage Uterine Cancer, Catherine Raciti, Hong Ye, Allison J. Hazy, Maha Saada Jawad

Posters

• Endometrial cancer is the most common gynecologic malignancy in the United States, with peak incidence at 63 years of age.¹

• PORTEC-2 trial established VBT alone as an effective modality for select high-intermediate risk patients.2

• There was no strict ABS guideline for dose fractionation; our institution adopted a 30Gy in 6 fractions regimen based on radiobiological calculations.3,4

• COVID-19 pandemic led to a shift towards 22Gy in 4 fractions

• Objective: Compare oncologic outcomes and toxicity between the 30Gy/6fx and 22Gy/4fx regimens.

• Hypothesis: Both regimens are well-tolerated and equally effective.

• Impact: Findings will inform clinical practice …


Ai Model For Predicting Asthma Prognosis In Children, Elham Sagheb, Chung-Il Wi, Katherine S King, Bhavani Singh Agnikula Kshatriya, Euijung Ryu, Hongfang Liu, Miguel A Park, Hee Yun Seol, Shauna M Overgaard, Deepak K Sharma, Young J Juhn, Sunghwan Sohn May 2025

Ai Model For Predicting Asthma Prognosis In Children, Elham Sagheb, Chung-Il Wi, Katherine S King, Bhavani Singh Agnikula Kshatriya, Euijung Ryu, Hongfang Liu, Miguel A Park, Hee Yun Seol, Shauna M Overgaard, Deepak K Sharma, Young J Juhn, Sunghwan Sohn

Faculty, Staff and Student Publications

BACKGROUND: Childhood asthma often continues into adulthood, but some children experience remission. Utilizing electronic health records (EHRs) to predict asthma prognosis can aid health care providers and patients in developing effective prioritized care plans.

OBJECTIVE: We aimed to develop artificial intelligence (AI) models using various clinical variables extracted from EHRs to predict childhood asthma prognosis (remission vs no remission) in different age groups.

METHODS: We developed AI models utilizing patients' EHRs during the first 6, 9, or 12 years of their lives to predict their asthma prognosis status at ages 6 to 9, 9 to 12, or 12 to 15 …


Association Of Delayed Asthma Diagnosis With Asthma Exacerbations In Children, Chung-Il Wi, Euijung Ryu, Katherine S King, Jung Hyun Kwon, Joshua T Bublitz, Miguel Park, Sergio E Chiarella, Jason D Greenwood, Thanai Pongdee, Lynnea Myers, Björn Nordlund, Sunghwan Sohn, Elham Sagheb, Bhavani Singh Agnikula Kshatriya, Dave Watson, Hongfang Liu, Beverley J Sheares, Carla M Davis, Wade Schulz, Young J Juhn May 2025

Association Of Delayed Asthma Diagnosis With Asthma Exacerbations In Children, Chung-Il Wi, Euijung Ryu, Katherine S King, Jung Hyun Kwon, Joshua T Bublitz, Miguel Park, Sergio E Chiarella, Jason D Greenwood, Thanai Pongdee, Lynnea Myers, Björn Nordlund, Sunghwan Sohn, Elham Sagheb, Bhavani Singh Agnikula Kshatriya, Dave Watson, Hongfang Liu, Beverley J Sheares, Carla M Davis, Wade Schulz, Young J Juhn

Faculty, Staff and Student Publications

Background: There is a significant delay between symptom onset and diagnosis of childhood asthma, but the impact of this delay on asthma outcomes has not been well understood.

Objectives: We sought to study the association of delayed diagnosis of asthma with asthma exacerbations (AEs) in children.

Methods: Using the Mayo Clinic birth cohort, we identified children with a diagnosis of asthma from electronic health records. We defined onset date as the date when subjects first met predetermined asthma criteria ascertained by an electronic health records-based natural language processing algorithm. Delay in diagnosis (DD) was defined as first diagnosis >30 days …


The Burden Of Care: Understanding Burnout Among Pediatric Healthcare Workers, Navya Khandavalli May 2025

The Burden Of Care: Understanding Burnout Among Pediatric Healthcare Workers, Navya Khandavalli

Theses/Capstones/Creative Projects

Burnout among pediatric healthcare professionals is a growing concern that impacts both employee well-being and the overall quality of patient care. The aim of this study is to analyze the definition of burnout and how healthcare organizations can implore strategies to help improve the mental and physical well-being of their staff. Analysis was done through a survey administered to healthcare employees recruited from pediatric clinics, the neonatal ICU, pediatric research, and pediatric rehabilitation facilities. Findings from the methods found that burnout is often defined as prolonged occupational stress in an individual and are often characterized by symptoms of emotional exhaustion, …


Pelvic Inflammatory Disease, Children's Mercy Kansas City May 2025

Pelvic Inflammatory Disease, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


On Death And Disease: How Physicians’ Perspectives Compare Across Specialties Through Written Work, Stephanie Anne C. Alkonga May 2025

On Death And Disease: How Physicians’ Perspectives Compare Across Specialties Through Written Work, Stephanie Anne C. Alkonga

Honors Capstones

Narrative medicine is a tool that the medical field is increasingly utilizing to cultivate patient-centered and culturally competent doctors and to reflect on lived experiences through texts that focus on psychosocial best practices. This study aims to examine the language used in physician-written works that address how physicians in different medical specialties treat the aging and the terminally ill, and how they view the deceased. Qualitative data guided by thematic questions will primarily be used in the analysis and comparison of these texts’ tone, rhetoric, diction, and similar literary devices to uncover if certain patterns arise across such specialties. Findings …


The Effects Of Aromatherapy On Postoperative Nausea And Vomiting (Ponv) Among Adult Population: An Integrative Research Review (Irr), Mary Estelle De Vera May 2025

The Effects Of Aromatherapy On Postoperative Nausea And Vomiting (Ponv) Among Adult Population: An Integrative Research Review (Irr), Mary Estelle De Vera

Covenant Nurses Week 2025

No abstract provided.


Early Mobilization In Post-Operative Cardiac Patients, Bailey Robertson, Trey Keesee May 2025

Early Mobilization In Post-Operative Cardiac Patients, Bailey Robertson, Trey Keesee

Covenant Nurses Week 2025

No abstract provided.


Do Hourly Neuro Exams Lead To Sleep Deprivation And Icu Delirium: A Research Review, Toni Gafford May 2025

Do Hourly Neuro Exams Lead To Sleep Deprivation And Icu Delirium: A Research Review, Toni Gafford

Covenant Nurses Week 2025

No abstract provided.


Evidence Based Research Review Of Remote Independent Chemotherapy/Immunotherapy Verification, Katrina Perkins, Hannah Holder, Marie St. Clair May 2025

Evidence Based Research Review Of Remote Independent Chemotherapy/Immunotherapy Verification, Katrina Perkins, Hannah Holder, Marie St. Clair

Covenant Nurses Week 2025

No abstract provided.


Every Patient Every Time: Hapi Bundle Implementation On Micu And Nsicu, Kelsey Sawyer, Sara Tucker, Stephan Smith May 2025

Every Patient Every Time: Hapi Bundle Implementation On Micu And Nsicu, Kelsey Sawyer, Sara Tucker, Stephan Smith

Covenant Nurses Week 2025

No abstract provided.


Got Rib Fractures? Pic This! Producing Improved Patient Outcomes In Trauma Related Rib Fractures, Pic Scores And Use Of Intercostal Nerve Blocks, Lynn Davis, Evelyn Miller, Lupita Quintanilla, Stephanie Padgett, Brandi Walden, Karen Dean May 2025

Got Rib Fractures? Pic This! Producing Improved Patient Outcomes In Trauma Related Rib Fractures, Pic Scores And Use Of Intercostal Nerve Blocks, Lynn Davis, Evelyn Miller, Lupita Quintanilla, Stephanie Padgett, Brandi Walden, Karen Dean

Covenant Nurses Week 2025

No abstract provided.


The Potential Of The Eat, Sleep, Console Method In The Neonatal Intensive Care Unit: An Integrative Research Review (Irr), Kelsey Seigman May 2025

The Potential Of The Eat, Sleep, Console Method In The Neonatal Intensive Care Unit: An Integrative Research Review (Irr), Kelsey Seigman

Covenant Nurses Week 2025

No abstract provided.


Strategic Innovation And Management By Nursing Leaders: Enhancing Icu Staffing For The Implementation Of A Rapid Response Team, Matthew Mitchell, Kelsey Sawyer, Sara Tucker, Stephan Smith, Stephanie Pigg, Jonathan Ortegon, Mitch Young May 2025

Strategic Innovation And Management By Nursing Leaders: Enhancing Icu Staffing For The Implementation Of A Rapid Response Team, Matthew Mitchell, Kelsey Sawyer, Sara Tucker, Stephan Smith, Stephanie Pigg, Jonathan Ortegon, Mitch Young

Covenant Nurses Week 2025

No abstract provided.


Impact The Utilization Of Evidenced Based Practices Has On Post Kidney Transplant Patient Outcomes, Judith Bautista, Vicky Loren Dela Cruz, Ervieneth Martin, Jennifer Mauricio, Alf Bernardino May 2025

Impact The Utilization Of Evidenced Based Practices Has On Post Kidney Transplant Patient Outcomes, Judith Bautista, Vicky Loren Dela Cruz, Ervieneth Martin, Jennifer Mauricio, Alf Bernardino

Covenant Nurses Week 2025

No abstract provided.


Allergies Coinciding With Central Sensitization Syndromes (Access), Jacqueline Morey, Alemu Fite, Carl Lauter, Matthew Sims May 2025

Allergies Coinciding With Central Sensitization Syndromes (Access), Jacqueline Morey, Alemu Fite, Carl Lauter, Matthew Sims

Posters

Significance of Reported Allergies: Many reported drug allergies are mislabeled side effects or misinterpretations, leading to suboptimal treatment, antibiotic resistance, and worse patient outcomes.¹

Central Sensitization Syndromes (CSS): CSSs are chronic pain conditions linked to altered sensory perception, including pain, fatigue, and neurologic dysfunction.² These patients may be more likely to misattribute medication side effects as allergies.

Previous Findings & Hypothesis: Prior research found high allergy reporting in interstitial cystitis and fibromyalgia—both CSS conditions.⁴ We hypothesized that other CSS diagnoses also correlate with increased allergy reporting, emphasizing the need for better allergy evaluation.


Epic Best Practice Alerts Increases Sep1 Orderset Usage, Mark Munir, Zachary Awad, Paul Bozyk, Ramin Homayouni May 2025

Epic Best Practice Alerts Increases Sep1 Orderset Usage, Mark Munir, Zachary Awad, Paul Bozyk, Ramin Homayouni

Posters

Sepsis is a massive, system-wide inflammatory response to an infection that can lead to multisystem organ failure.1 Sepsis has a very high mortality rate of 20-50% in patients with severe sepsis and is the 10th leading cause of death in the United States.2 One of the most significant ways of reducing mortality from sepsis is timely detection and initiation of treatment in septic patients.3

Electronic medical records such as Epic have implemented sepsis warning algorithms and alerts to facilitate quicker detection of sepsis and thus earlier initiation of treatment. The goal of this study is to determine if an Epic …


Aquablation Compared With Simple Prostatectomy For Prostate Volumes >80 Grams, Joshua Kuperus, Minhaj Jabeer, Aidan Kennedy, Paul Horning, Greg Palmateer, Bernadette M.M. Zwaans, Jason Hafron, Kenneth M. Peters May 2025

Aquablation Compared With Simple Prostatectomy For Prostate Volumes >80 Grams, Joshua Kuperus, Minhaj Jabeer, Aidan Kennedy, Paul Horning, Greg Palmateer, Bernadette M.M. Zwaans, Jason Hafron, Kenneth M. Peters

Posters

• Benign prostatic hyperplasia (BPH) is the most common benign urological disease in men. 1

• Moderate-to-severe lower urinary tract symptoms (LUTS) from BPH affect 30% of men over 502 and medical treatment often fails for men with moderate-to-severe symptoms, leading them to seek surgical options. 3

• Transurethral resection of the prostate (TURP) remains the gold standard for prostates less than 80 mL; simple prostatectomy (SP) remains the standard for larger prostates.

• Aquablation (Aqua) is a novel BPH procedure that may be used for both small and large prostates from 50 to 150 mL. 4

• Although TURP …


Bisphosphonate Treatment In Pediatric Patients With Rare Ovarian Malignancy And Hypercalcemia: A Case Series, Seth Lamb, Samhita Bhattarai, Jennifer Boyd May 2025

Bisphosphonate Treatment In Pediatric Patients With Rare Ovarian Malignancy And Hypercalcemia: A Case Series, Seth Lamb, Samhita Bhattarai, Jennifer Boyd

Posters

Objective: To describe the presentation, management, and outcomes of severe hypercalcemia in two adolescent females secondary to ovarian malignancy. Methods: The case series includes two adolescent female patients, aged 11 and 16, diagnosed with rare ovarian malignancies and associated hypercalcemia. The 11-year-old female was diagnosed with small cell carcinoma of ovary while the 16-year-old was diagnosed with dysgerminoma. Both patients presented with abdominal pain, nausea and constipation. The 11-year-old received zoledronic acid while the 16-year-old received pamidronate. Serum calcium level, symptoms and adverse effects were monitored before and after both medications. Results: Both patients presented with severe hypercalcemia. The 11-year …


Physician Use Of Progesterone In Transgender Adolescents: A Survey, Samhita Bhattarai, Michelle Knoll May 2025

Physician Use Of Progesterone In Transgender Adolescents: A Survey, Samhita Bhattarai, Michelle Knoll

Posters

Objectives To evaluate the current perspective and clinical practices of physicians regarding the use of synthetic progestins as an adjunct to estrogen therapy in transfeminine adolescents. The survey focuses on perceived benefits, risks and overall efficacy in gender affirming hormone therapy. Methods A cross sectional survey was conducted among physicians who care for transfeminine patients. The survey included questions regarding their specialty, practice setting, age range of patients. Data was also collected regarding their indication for use, perceived benefits (e.g. breast development) and rationale if not using progestins for this purpose. Results Of 110 physicians who participated in the survey, …


Preliminary Assessment For Quality Improvement Of Hypertension Management In Kenya, Shubhangi Singh May 2025

Preliminary Assessment For Quality Improvement Of Hypertension Management In Kenya, Shubhangi Singh

Honors Theses

Hypertension is a leading contributor to cardiovascular disease (CVD) morbidity and mortality worldwide, with a disproportionate burden in low- and middle-income countries (LMICs). Despite relatively low rates of common behavioral risk factors, the Kasigau region of Kenya experiences high prevalence of hypertension and hypertension-related complications. This study explores self-efficacy, health beliefs, and management behaviors among adults in Kasigau to provide pilot quality improvement data for providers and future intervention planning. A cross-sectional, randomized survey of 45 adults was conducted at the Bughuta Clinic in southeastern Kenya. Participants completed a five-question hypertension-specific, self-efficacy assessment and a health belief model-based survey, with …


The Development Of A Trauma Interventional Radiology Alert Protocol Reduces Time To Vessel Puncture In Cases Of Active Hemorrhage., Aahad Khan, Akhil Gangisetty, Steve Mitchell, Nick Daughtery, Brent Goslin, William B Devoe, John Bach May 2025

The Development Of A Trauma Interventional Radiology Alert Protocol Reduces Time To Vessel Puncture In Cases Of Active Hemorrhage., Aahad Khan, Akhil Gangisetty, Steve Mitchell, Nick Daughtery, Brent Goslin, William B Devoe, John Bach

Trauma and Acute Care Articles

Introduction Trauma continues to be a major cause of death in the United States, with uncontrolled bleeding contributing to a significant portion of trauma-related fatalities. In recent years, the management of hemorrhagic trauma patients has expanded to include interventional radiology (IR). The American College of Surgeons Committee on Trauma recommends that Level 1 and 2 trauma centers ensure IR availability within 60 minutes of the decision to proceed with angiography. Delays in IR intervention are associated with poorer outcomes and increased mortality. To address this, our Level 2 trauma center developed and implemented an institutional protocol involving trauma surgeons, interventional …


Rectosigmoid Intussusception Due To A Nonmalignant Etiology: An Extremely Rare Cause Of Acute Lower Gastrointestinal Bleeding In An Elderly Patient, Kashif Ali, Samra Sohail, Grecia Dominguez Rivera, Valeska Balderas May 2025

Rectosigmoid Intussusception Due To A Nonmalignant Etiology: An Extremely Rare Cause Of Acute Lower Gastrointestinal Bleeding In An Elderly Patient, Kashif Ali, Samra Sohail, Grecia Dominguez Rivera, Valeska Balderas

School of Medicine Publications

An intussusception at the rectosigmoid junction with acute gastrointestinal bleeding is exceedingly rare. We present a case of an 88-year-old man who presented in the emergency department with bilateral lower quadrant abdominal pain and frank rectal bleeding for 2 days. A computed tomography abdomen pelvis angiogram with contrast showed a target sign, and a flexible sigmoidoscopy showed congested bowel, ischemia, frank blood, and intussusception at the rectosigmoid junction. He underwent an exploratory laparotomy with the removal of the affected part. The pathology and the peritoneal fluid cytology results came out negative for dysplasia and malignancy.