Medical Specialties Commons^™

Mycosis Fungoides With Thrombotic Microangiopathy And Major Central Nervous System Manifestations, T. A. Chapel, S. M. Saeed, B. W. Steinhauer

Henry Ford Hospital Medical Journal

A case of mycosis fungoides is presented which terminated in death by an acute central nervous system illness. Autopsy revealed thrombotic microangiopathy. This is felt to be the first report of thrombotic thrombocytopenic purpura occurring in a patient with mycosis fungoides. Since thrombotic thrombocytopenic purpura has been reported in association with other malignancies, the association of these relatively rare disorders may represent more than a coincidence.

Renal Cell Carcinoma Masquerading As A Pancreatic Pseudocyst: A Case Report, Stuart J. Kingma, Hubert M. Allen

Henry Ford Hospital Medical Journal

A case is reported in which an abdominal mass was treated initially as a traumatic pseudocyst of the pancreas. Subsequent studies elucidated the true nature of the lesion, a renal cell carcinoma. The use of visceral arteriography as a definitive diagnostic tool is illustrated by this case.

Immunoglobulin Levels In Spinal Fluid And Saliva By Direct Immunochemical Assay And Microscopic Measurements, Hajime Hayashi, Gerald A. Logrippo, Mary Perry

Henry Ford Hospital Medical Journal

The immunochemical procedure used in this hospital for serum immunoglobulins (Igs) has been modified to increase sensitivity (5-to-20-fold) so that minute quantities of immunoglobulins can now be measured directly in unconcentrated body fluids. Normal spinal fluid Ig levels (±2 S.D. from normal means) were found to be: 0.01-0.21 mg/100 ml for IgA; 0.5-2.50 mg/100 for IgG: and no detectable quantities for IgM. Normal (pooled) salivary Ig levels were found to be 0.01-2.25 mg/100 ml for IgA: trace quandties to 1.85 mg/100 ml for IgG: and no detectable quantities for IgM. Spinal fluid and salivary Igs were assayed in 227 adults …

The Effect Of Phenobarbital On Serum Bilirubin Of Full Term Infants: A Controlled Study, Mary J. Kokosky, Harold A. Falconer, Lester Weiss

Henry Ford Hospital Medical Journal

Three bundled twenty-eight infants weighing more than 2500 grams were studied for the effect of low dose phenobarbital (15 mg/day) upon third and fifth day serum bilirubin levels. The groups were divided according to sex, race and type of treatment. Controls were made for the possible effect of the 14% ethanol contained in phenobarbital elixir. It was found that males had higher mean serum bilirubin levels than females, Caucasians had higher mean serum bilirubin levels than Negroes, and control infants had higher serum bilirubin values than those infants treated with phenobarbital. However, in those patients who had lower serum bilirubin …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Newsletter, Volume 15, Number 02, November 1970

Newsletter: A Report to Physicians of Texas Archives

• Rehabilitation Theme of 15th Clinical Conference
• Pathology Symposium To be Held
• Clinical Abstract
• Staff Publications

The Alumnus, Vol.7 No.1, Kansas City College Of Osteopathy And Surgery, Jim Zahnd

Alumnus (1968-1971)

Contents: Positive Image by Students -- Increase Basic Sciences -- In Life and Death . . . "Anglo" D.O. Re-Shapes Texas Town -- Understanding Increased During D.O.s' Soviet Tour -- Golden Gloves Taps Dr. Verner J. Ames -- Harvey Acton To Helm Of College's Hospitals -- Alumni News -- Retirement Claims 4 KCCOS Veterans.

Newsletter, Volume 15, Number 01, October 1970

Newsletter: A Report to Physicians of Texas Archives

• Tenth International Cancer Congress
• President's Salute
• Pharmacist Award
• Cancer Experets Discuss Air Pollution
• Governor's Proclamation
• President Nixon Salutes Congress
• Greeting From Governor Smith
• TV--A First for the International Cancer Congress
• Congress Entertainment
• 72 Countries Fight Cancer in '70
• Rapporteur Reports
• MDAH Staff Membes Active in Congress
• Ecologist Will Help Develop Science Park
• Anderson Physicians Help Establish Cowdry Histology Prize
• Clinical Abstracts
• MDAH Physicists Probe Californium Therapy

Assessing Attempted Suicide, Walter J. Cassidy

Henry Ford Hospital Medical Journal

Fifty successive patients attempting suicide are assessed from the standpoint of communication (how, when and to whom), manipulativeness, impulsiveness and the dangerousness of the pattern of behavior involved in the attempted suicide. This assessment is meant to clarify the component motivations of suicidal behavior, appeal and self-destruction. The earlier, more obvious the communication, the more definite is the manipulation, the more readily apparent the appeal function. Conversely the later, the less obvious the communication or the absence of communication, the more subtle or absent manipulation the greater is the dominance of self-destructive motivation over the appeal function of the attempted …

A Decade Of Heart Surgery And A Look Into The Future, Conrad R. Lam

Henry Ford Hospital Medical Journal

No abstract provided.

Percutaneous Absorption Of Betamethasone-17-Benzoate, George R. Mikhail

Henry Ford Hospital Medical Journal

Percutaneous absorption of betamethasone-17-benzoate, a new topical corticosteroid, was sufficient enough to result in adrenocortical suppression in patients with psoriasis or atopic dermatitis when 0.025% of the steroid cream was applied under occlusion to 30% or more of the body surface, using 9 gm or more of the preparation. The adrenal function returned to normal within a short time after the cream was discontinued.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Quantitative Determination Of C-Reactive Protein (Crp) By Micro-Double Diffusion Technic, Hajime Hayashi, Gerald A. Logrippo, Mary Perry

Henry Ford Hospital Medical Journal

C-reactive protein (CRP) determinations in serum have been evaluated by two methods: the capillary tube method (presently in use) and the double diffusion technic (a newly developed procedure standardized in this laboratory). Advantages of the double diffusion technic are (1) quantitation of CRP in milligrams per 100 ml of serum, (2) differentiation of CRP from non-specific precipitates often found in patients' sera, and (3) increased sensitivity. A normal range of CRP levels has been established by analyzing serum from 750 supposedly healthy blood bank donors. Ninety-five percent of the donor population possess less than 1.0 mg of CRP per 100 …

Hypophyseal Growth Hormone Ii. Interaction With Other Hormones, M. Saeed-Uz-Zafar, Raymond C. Mellinger, Lewis B. Morrow

Henry Ford Hospital Medical Journal

Growth hormone (GH) synthesis and release is controlled by hypothalamic GH releasing factor. Thyroid hormones, androgens and estrogens in physiologic concentrations enhance GH secretion but a controlling role for glucagon and vasopressin in GH release is not established. Under stress, ACTH directly facilitates GH release while the similar action of the catecholamines is mediated by the a-adrenergic receptors. Though physiologic doses of glucorticoids and progestins do not affect GH liberation, prolonged administration of medroxyprogesterone acetate or of glucocorticoids in high dosage will decrease blood levels or blunt Gti responsiveness. GH enhances the release of insulin. A shift in adrenal steroid …

Health Nurse Clinician: An Extended Role For The Professional Nurse, C. E. Rupe, Diana Downs, Diane L. Kerr, William W. Hardy

Henry Ford Hospital Medical Journal

A program to upgrade the level of nursing involvement in patient care has been established in conjunction with Wayne Slate University. Offered as a possible solution to the shortage of health care personnel, the master's degree program would result in an upward movement of medical personnel and provide more continuity of care to the patient. More specifically, the trained Health Nurse Clinician would be able to provide better nursing care because of the nurse's greater awareness of the patient's health problem. She (or he) could also free the physician from some of the time-consuming aspects of routine physical examination without …

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.

Effect Of Normal Menstrual Cycle On Platelet Adhesiveness, Janet Mak Yeung

Henry Ford Hospital Medical Journal

Platelet adhesiveness was measured at intervals during the menstrual cycle in six normal females. Three normal males were studied during the .tame period of time to serve as controls. There was a significant difference of the variation of platelet adhesiveness between the two groups during the period of 30 days. Five out of six females showed much greater fluctuation than the males. No definite trend was observed in the platelet adhesiveness of females in relation to the menstrual cycle in this preliminary study. A larger number of samples from the population will be necessary to obtain a more accurate result.

Mixed Gonadal Stroma Cell Tumor Of The Testicle: A Case Report, Gerald B. Farrow, Arthur J. Johnson

Henry Ford Hospital Medical Journal

A specialized gonadal stromal tumor of mixed nature found in a 20-year-old Negro male is reported. Although the tumor had been present for six to seven years, there was no evidence of metastases or of hormonal imbalance. Reference is made to the confusing nomenclature of these rare tumors.

Spectacular Elevations Of Serum Alkaline Phosphatase: Clinical And Pathological Correlation Roy B., Roy B. Patton

Henry Ford Hospital Medical Journal

The diseases responsible for extremely high serum alkaline phosphatase aclivily in 45 patients were proliferative bone disease (10 patients) and hepato-biliary tract disease (35 patients). Conditions found in these patients that are not usually thought to cause such high phosphatase levels were: drug-induced cholestasis (6 patients), non-malignant extra-hepatic bile duct obstruction (3 patients), biliary or portal cirrhosis (5 patients), and primary hyperparathyroidism with generalized osteitis fibrosa (1 patient).

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

The Hypocalcemic Effects Of Actinomycin D And Mithramycin, Eduardo L. Reyes, Robert W. Talley

Henry Ford Hospital Medical Journal

Both actinomycin D and mithramycin are useful agents in the treatment of cancer. They can also produce hypocalcemia, a comparatively rare phenomenon in cancer. Two such cases are presented in detail. Neither patient had the classic symptoms of hypocalcemia. Instead, the clinical picture was more compatible with hypercalcemia. The mechanism of action of each drug is explained; therapeutic implications are made with regards to their synergistic effects when used in combination with the standard calcium-lowering agents. Attention is drawn to the inhibitory action of these two agents on the calcium-mobilizing effect of the parathyroid hormone. The hypocalcemic effects of these …

In Vitro Kidney Preservation Techniques, S. G. Dienst

Henry Ford Hospital Medical Journal

The advantages of adding hyperbaria, low flow perfusion, and protein colloid to hypothermia at 0° C for kidney preservation are described. The possibilities of longer preservation at higher temperatures are discussed.

Hypophyseal Growth Hormone: I. Control Of Secretion, M. Saeed Zafar, Raymond C. Mellinger, Lewis B. Morrow

Henry Ford Hospital Medical Journal

Growth hormone (GH) is a major hormone of the anterior pituitary gland. Once established, its secretion continues throughout life. GH was first recognized in 1866 as a factor controlling growth. More recently, it has been demonstrated as a vital regulator of fat, carboyhdrate and protein metabolism. In fact, GH influence on the intermediary metabolism is the major mechanism by which growth and development are regulated. Numerous hormonal and nonhormonal factors have been shown to modify the basic pattern of GH synthesis and secretion. In this article we have reviewed some of these nonhormonal factors.

Surreptitious Ingestion Of Oral Anticoagulants, Thomas H. Greidanus, Ellis J. Van Slyck, Raymond W. Monto

Henry Ford Hospital Medical Journal

Hypoprothrombinemia secondary to surreptitious ingestion of coumarin or indanedione anticoagulants may be a difficult diagnosis for the unsuspecting physician. Four such case reports are presented. The disease should be suspected if the prothrombin time is markedly elevated and the individual is associated with the medical profession or has had previous treatment with oral anticoagulants. The diagnosis is confirmed by finding a deficiency in Factors II (prothrombin), VII, IX, and X and the presence of the coumarin or indanedione anticoagulant in the blood. The motive generally is that of gaining attention rather than committing suicide. Liver disease. Vitamin K deficiency states …

Double Contrast Arthrography Of The Knee, Peter C. Larowe, Robert S. Ormond, Edwin Guise

Henry Ford Hospital Medical Journal

Arthrography is a safe and relatively simple diagnostic procedure which provides an accurate and graphic preoperative means of defining pathology of the knee. In those cases where the expeditious evaluation and diagnosis of knee injury are of prime importance, ie, the athlete and industrial compensation case, arthrography provides a significant contribution. The clinical pathological features, salient anatomy and technic of study of internal derangements of the knee are discussed. Selected double contrast arthrograms illustrate normal and abnormal findings. Arthrotomies were performed in 20 of the 32 patients in this study with a positive arthrogram-arthrotomy correlation of 85%.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Immunologic Status Of Uremic Patients, Gerald A. Logrippo, C. E. Rupe, Hajime Hayashi, Dean Lesher

Henry Ford Hospital Medical Journal

The immunologic status of 25 uremic patients was studied with a battery of tests evaluating the humoral and cytological aspects of immunity. The individual's humoral immune status was evaluated as follows: quantitation of the three major serum immunoglobulins (IgG, IgA and IgM) expressed in mg/100 ml of serum and compared to established normal clinical standards (±2 SD/mean); qualitation of IgG and IgM evaluated by specific virus antibody titers and antitoxin values associated with IgG and by isoagglutinin tilers of the ABO blood groups associated with IgM. Immunoglobulin status is grouped into hyper- and hypo-immunoglobulin variations from normal and correlated with …

Cephalexin: In Vitro And In Vivo Studies, Frank Cox Jr., Edward L. Quinn, Bienvenido G. Gatmaitan, Nancy Peterson

Henry Ford Hospital Medical Journal

Cephalexin, a derivative of cephalosporin C, produces high serum and urine concentrations after oral administration. In addition, it shows good activity in vitro against most gram-positive and some gram-negative organisms. This study reports the in vitro susceptibility to cephalexin of a series of clinical isolates, the serum levels and urine concentrations in human volunteers and the results of its use in infections due to susceptible organisms. Results of in vitro susceptibility testing reveal that cephalexin was effective against most strains of the gram-positive organisms tested — group A streptococci, pneumococci, and staphylococci — although the MIC's are higher than those …

Hfh In The News

Henry Ford Hospital Medical Journal

No abstract provided.