Medical Specialties Commons^™

Vision And Hearing Loss In The Older Adult - “Double Trouble”, Paige Berry

Case Studies from Age in Action

Educational Objectives

1. How to recognize age related vision and hearing loss.

2. How the loss of both vision and hearing affect the individual's day to day functioning.

3. Services and technology available to assist the professional in better meeting the needs of the individual who is experiencing a vision and hearing loss.

Functions Of The Rat's Temporal Association Cortex In Higher Perceptual Functions, Summer L. Maki

The Corinthian

The role of the rodent temporal cortex in relational perception was investigated. Eighteen Long Evans rats were separated into three surgical groups (sham, partial striate, and Te2/3) and trained on a preoperative and postoperative discrimination task. The rats were then presented a series of relational judgement trials consisting of both between category judgments and within category judgments. It was hypothesized that the rats with Te2/3 lesions would perform as well as controls on the preoperative and postoperative discrimination task, but show a considerable behavioral dysfunction on the tests of visual relational perception. The results showed no differences across groups in …

Health Professions Division Catalog Academic Year 2001-2002, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

2000 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center.

The Process Of Clinical Trials: A Model For Successful Clinical Trial Participation, Cecile A. Lengacher, Lois L. Gonzalez, Rosemary Giuliano, Mary P. Bennett, Charles E. Cox, Douglas S. Reintgen

Nursing Faculty Publications

No abstract provided.

Com Outlook January 2001, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Is Extended Volume Of External Beam Irradiation Beneficial In Post-Esophagectomy High Risk Patients Receiving Combined Chemoradiation Therapy?, E. Yu, A. R. Dar, R. Ash, G. Videtic, P. Truong, L. Stitt, A. Tomiak, M. Vincent, R. Malthaner, I. Craig, E. Brecevic, W. Kocha, R. Inculet, M. Lefcoe

Oncology Presentations

OBJECTIVE: To assess the value of extended volume irradiation with anastomotic coverage in high risk resected esophageal cancer patients.

METHOD: A retrospective study was undertaken at LRCC from 1989-1999 for high risk resected esophageal cancer patients. Adjuvant treatments consisted of 4 cycles of chemotherapy (epirubicin/fluorouracil/cisplatin or cisplatin/fluorouracil), and local regional irradiation with or without coverage of the anastomotic site. Radiation dose ranged from 45-60Gy at 1.8-2.0 Gy/fraction given with initial anterior-posterior/posterior-anterior arrangement with either extended (with anastomotic coverage) or small (without anastomotic coverage) field followed by oblique fields for boost.

RESULT: One hundred eighty-eight charts were reviewed. Seventy-two patients were …

The Concentration Of Three Anti-Seizure Medications In Hair: The Effects Of Hair Color, Controlling For Dose And Age, Tom Mieczkowski, Aristidis M. Tsatsakis, Michael Kruger, Thanasis Psillakis

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

This paper assess the relationship between the quantity of three anti-seizure medications in hair and the color of the analyzed hair, while controlling for the effects of dose, dose duration, and patient age for 140 clinical patients undergoing anti-seizure therapy. Three drugs are assessed: carbamazepine (40 patients), valproic acid (40 patients), and phenytoin (60 patients). The relationship between hair assay results, hair color, dose, dose duration, and age is modeled using an analysis of covariance. The covariance model posits the hair assay results as the dependent variable, the hair color as the qualitative categorical independent variable, and dose, …

Clinical Presentation And Treatment Outcome In Children With Nephroblastoma In Kenya, F.K. Abdallah, William Macharia

Paediatrics and Child Health, East Africa

Objective: To review the clinical presentation and management of children with nephroplastoma and the factors influencing the outcome at Kenyatta National Referral and Teaching Hospital (KNH).

Design: This was a retrospective case series study based on secondary data accumulated between 1990 and 1996.

Setting: The relevant data were extracted from records of all children aged 12 years and below, admitted for cancer at KNH, Nairobi.

Results: Out of 803 children with cancer, 71 (8.8% ) had histologically proven nephroblastoma. At presentation, 1.5% were in stage I, 13.2% stage II, 36.8% stage III, 41.2% stage IV and 7.4% stage V. Eighty …

Sustained Remission In A Case Of Lupus Nephritis With Cyclosporin Therapy, M A. Rabbani, S M. Shah, A Ahmad

Section of Nephrology

Systemic lupus erythematosus (SLE) in severe form still presents a major therapeutic challenge. Aggressive treatment of severe renal lesions has improved the prognosis of renal disease over the last decade. However, this benefit is quite frequently offset by the side effects and toxicity of the treatment. Moreover, the disease may appear to be poorly responsive to treatment with steroids and cytotoxic drugs. We report a case of lupus nephritis that relapsed despite having adequate steroid and cytotoxic therapy, but later was successfully treated with cyclosporin. Fifteen months after discontinuing the treatment with cyclosporin, the patient continued to remain in remission.

Department Of Radiology-Annual Executive Summary Report-July 1, 2000 To June 30, 2001, David C. Levin , M.D.

Department of Radiology Administrative Documents and Reports

101 page Department of Radiology Annual Executive Summary Report, July 1, 2000 to June 30, 2001, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States.

Hormonal And Barrier Methods Of Contraception, Oncogenic Human Papillomaviruses, And Cervical Squamous Intraepithelial Lesion Development, Ann L. Coker, Laura C. Sanders, Sharon M. Bond, Tsilya Gerasimova, Lucia Pirisi

CRVAW Faculty Journal Articles

We assessed the influence of hormonal (oral, injectable, or levonorgestrel [Norplant, Wyeth-Ayerst, Philadelphia, PA]) and barrier methods of contraception on the risk of cervical squamous intraepithelial lesions (SIL), while adjusting for high-risk (HR) HPV infection. Subjects were women receiving family planning services through the state health department clinics from 1995 to 1998. We selected 60 cases with high-grade cervical/SIL (HSIL) and 316 with low-grade cervical/SIL (LSIL) and controls (427 women with normal cervical cytology) and analyzed cervical DNA for HR-HPV, using Hybrid Capture I (Digene; Gaithersburg, MD).When assessing ever use, duration, recency, latency, and age at first use, neither oral …

Cerumen Composition By Flash Pyrolysis-Gas Chromatography/Mass Spectrometry, Craig N. Burkhart, Michael A. Kruge, Craig G. Burkhart, Curtis Black

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Objective: To assess the chemical composition of cerumen by flash pyrolysis-gas chromatography/mass spectrometry.

Study Design: Collected earwax specimens were fractionated into residue and supernatant by means of deoxycholate. This natural bile acid produces significantly better disintegration of earwax in vitro than do presently available ceruminolytic preparations, and also has demonstrated excellent clinical results in vivo to date.

Patients: The sample for analysis was obtained from a patient with clinical earwax impaction.

Results: The supernatant is composed of simple aromatic hydrocarbons, C₅-C_{l 7} straight-chain hydrocarbons, a complex mixture of compounds tentatively identified as diterpenoids, …

What Is The Relationship Between Activity, Social Support And Health-Related Quality Of Life In People Who Are Sixty Years Of Age And Older?, Jaqueline Ebbott

Theses : Honours

Over one third of individuals aged sixty years and older have health conditions which limit their ability to live an independent and active life. With the older Australian population increasing, the prevention of functional decline and preservation of wellbeing in this age group has become a major clinical focus in gerontology research. Therefore an important goal of health professionals is to identify behavioural factors which encourage wellbeing and quality of life in this age group. The purpose of the present study was to explore the importance of physical activity passive activity (activities such as craft, reading and board games) and …

Vital Signs, Winter 2001, Boonshoft School Of Medicine

Vital Signs

A twenty-three page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes feature articles, a student profile, faculty notes, and more.

An Analysis Of Anemia And Child Mortality, B.J. Brabin, Zul Premji, F. Verhoeff

Pathology, East Africa

The relationship of anemia as a risk factor for child mortality was analyzed by using cross-sectional, longitudinal and case-control studies, and randomized trials. Five methods of estimation were adopted: 1) the proportion of child deaths attributable to anemia; 2) the proportion of anemic children who die in hospital studies; 3) the population-attributable risk of child mortality due to anemia; 4) survival analyses of mortality in anemic children; and 5) cause-specific anemia-related child mortality. Most of the data available were hospital based. For children aged 0-5 y the percentage of deaths due to anemia was comparable for reports from highly malarious …

Pneumoperitoneum Following Mechanical Ventilation In A Child, Fazal Hameed Khan, Nadeem Ahmad

Department of Anaesthesia

No abstract provided.

Department Of Radiation Oncology And Kimmel Cancer Center, Thomas Jefferson University, The Intronic G13964c Variant In P53 Is Not A High-Risk Mutation In Familial Breast Cancer In Australia., Anna Marsh, Amanda B Spurdle, Bruce C Turner, Sian Fereday, Heather Thorne, Gulietta M Pupo, Graham J Mann, John L Hopper, Joseph F Sambrook, Georgia Chenevix-Trench

Department of Radiation Oncology Faculty Papers

BACKGROUND: Mutations in BRCA1 and BRCA2 account for approximately 50% of breast cancer families with more than four affected cases, whereas exonic mutations in p53, PTEN, CHK2 and ATM may account for a very small proportion. It was recently reported that an intronic variant of p53--G13964C--occurred in three out of 42 (7.1%) 'hereditary' breast cancer patients, but not in any of 171 'sporadic' breast cancer control individuals (P = 0.0003). If this relatively frequent occurrence of G13964C in familial breast cancer and absence in control individuals were confirmed, then this would suggest that the G13964C variant plays a role in …

Oncolog, Volume 46, Number 01, January 2001, Kerry L. Wright, Dawn Chalaire, Emil J. Freireich Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• New Melanoma Staging System Reflects Key Prognostic Factors
• House Cell: Preventing Cancer: Food for Thought
• Educational Conferences Explore Issues Related to Cancer Care and Research
• DiaLog: Leukemia: Setting the "Stage" for Effective Treatments, by Emil J. Freireich, MD, Professor, Department of Leukemia
• Updated M. D. Anderson Website Designed to Meet the Online Needs of Patients and Physicians

Epidemiological Features Of Aplastic Anaemia In Pakistan, Salman Adil, G. N. Kakepoto, Mohammad Khurshid, I. A. Burney

Department of Pathology and Laboratory Medicine

Objective: To complete the data on the demographic features of patients diagnosed to have aplastic anemia at a single institution over a 7.5 years period. Methods: Demographic information was retrieved from the patients medical records retrospectively as well as prospectively of those patients who presented with features of aplastic anaemia. Their diagnosis was confirmed by performing a complete blood count and bone marrow trephine.
Results: One hundred and forty four patients were diagnosed to have aplastic anemia; there were 106 males and 38 females. Their ages ranged from 2 to 75 years, with a median of 17 years, …

Impaired Splenic Function In Systemic Amyloidosis: Diagnostic Importance Of Peripheral Blood Film, F. Bilwani, Salman Adil, G. N. Kakepoto, Mohammad Khurshid, A. Ahmed

Department of Pathology and Laboratory Medicine

We describe case of a 40 year old male, who went on to developed systemic amyloidosis 3 years after the diagnosis of chronic renal failure. The diagnosis of systemic amyloidosis was suspected upon a routine examination of periheral blood film showing features of hyposlenism. We would like to highlight the importance of examination of pheripheral blood film in patients with renal failure for the diagnosis of extensive systemic amyloidosis which occasionally leads to functional hyposplenism, recognized by the presence of abnormal red cell morphology and reduced splenic uptake on isotope scan¹.

Reovirus 1/L As A Model To Study The Induction Of Optimal Immunity At Mucosal And Systemic Sites, Sherry Renee Crowe

MUSC Theses and Dissertations

Achieving protective immunity at mucosal sites is critically important for effective immunization against pathogens that colonize the host via the wet epithelium. We utilized reovirus 1/L infection of mice to study immunization strategies for the induction of optimal humoral and cell-mediated immunity at mucosal surfaces. The humoral and cell-mediated responses at mucosal and systemic sites were monitored following upper respiratory tract, or systemic inoculation. Utilizing these models, we found that the combined upper and lower respiratory tract inoculation resulted in optimal humoral immunity proximally (in the respiratory tract), distrally (in the oral, gastrointestinal, and urogenital tracts), and systematically. This immune …

Physician Assistant Class Of 2001, Philadelphia College Of Osteopathic Medicine

All Yearbooks

Includes the White Coat Ceremony, Retreat at Camp Ockanickon, National Physician Assistant Day 1999, Classroom candids.

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2001), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 2001 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Opening Remarks
• In the Mail
• PCOM Updates
• Meet the Prez
• This Doctor Gets Personal
• Founders Day Honorees
• PCOM MEDNet
• Board Profile
• Alumni Board Profile
• Off to Camp – With Some Very Special Children
• Class Notes
• In Memoriam
• My Turn: New Essay Section
• 2^nd Annual PCOM Alumni Weekend
• Coming Events

Cellular Senescence: Ex Vivo P53-Dependent Asymmetric Cell Kinetics., Lakshmi Rambhatla, Shirley A. Bohn, Patrizia B. Stadler, Jonathan T. Boyd, Ronald A. Coss, James L. Sherley

Department of Radiation Oncology Faculty Papers

Although senescence is a defining property of euploid mammalian cells, its physiologic basis remains obscure. Previously, cell kinetics properties of normal tissue cells have not been considered in models for senescence. We now provide evidence that senescence is in fact the natural consequence of normal in vivo somatic stem cell kinetics extended in culture. This concept of senescence is based on our discovery that cells engineered to conditionally express the well-recognized tumor suppressor protein and senescence factor, p53, exhibit asymmetric cell kinetics. In vivo, asymmetric cell kinetics are essential for maintenance of somatic stem cells; ex vivo, the same cell …

Cardiac Hypertrophy, Heart Failure, And Regulation Of Microtubule Stability, Kristie Lynn Beaton-Blade

MUSC Theses and Dissertations

This work focused on the regulation of the different isotypes of beta-tubulin during cardiac hypertrophy, with the specific hypothesis that increased levels of the beta I isotype leads to the increase in microtubule density seen during hypertrophy. Partial cDNAs for the three beta-tubulin isotypes expressed in the heart (I, II, and IV) have been cloned and used to show that there is a differential upregulation of the beta I and beta II isotypes during cardiac hypertrophy. Messenger RNA half-life studies of cells isolated from hypertrophied myocardium have shown that this upregulation is due to increased transcription of the genes encoding …

West Bank And Gaza: Stress The Importance And Cost-Effectiveness Of Postpartum Care, Frontiers In Reproductive Health

Reproductive Health

To assess maternal health care in the West Bank and Gaza, the Health, Development, Information, and Policy Institute conducted a study from May to August 2000. This study served as a baseline for the Pilot Health Project (PHP), which seeks to improve antenatal and postpartum services in three areas of the West Bank and Gaza. Seven local and international agencies are implementing PHP in collaboration with the Palestinian Ministry of Health and with funding from the U.S. Agency for International Development. Data sources for the baseline study consisted of service statistics, interviews with health-care providers, and exit interviews with antenatal, …

Cisjordania Y Gaza: Subraye La Importancia De La Atención Postparto Y Su Cost-Efectividad, Frontiers In Reproductive Health

Reproductive Health

El Instituto de Salud, Desarrollo, Información y Políticas realizó un estudio de mayo a agosto de 2000 para evaluar la atención a la salud materna en Cisjordania y Gaza. Dicho estudio sirvió de línea basal para el Proyecto Piloto de Salud (PHP, por sus siglas en inglés), cuyo objetivo es mejorar los servicios prenatales y postparto en tres áreas de esa región. Siete agencias locales e internacionales implementan el PHP con la colaboración del Ministerio de Salud palestino y el patrocinio de la Agencia de los Estados Unidos para el Desarrollo Internacional. Las fuentes de la información para el estudio …

Reproductive Tract Infections: A Guide For Programme Managers, Sarah Hawkes, Anjali Nayyar, Johannes Van Dam, Kevin R. O'Reilly, Bidia Deperthes, Dinesh Agarwal

Reproductive Health

Reproductive tract infections (RTIs) including sexually transmitted infections represent a silent worldwide pandemic that adversely impacts the reproductive health (RH) of women and men. Various community- and hospital-based studies in India have provided insights into the magnitude of the problem. The International Conference on Population and Development (1994) emphasized integration of RH services to meet the needs of men and women especially with prevention and management of RTIs/STIs. The emergence of HIV and the identification of STIs as a risk factor for the spread of HIV have further lent a sense of urgency for a programmatic response to address this …

A Noninvasive Test For Vesico-Ureteric Reflux In Children, R. A. Mevorach, B. Cilento, S. Zahorian, C. Badgett, R. Walker, A. Atala, S. Iannello, M. Meyer

Electrical & Computer Engineering Faculty Publications

Objective To report the development and testing of a device for the noninvasive diagnosis of vesico‐ureteric reflux (VUR) which avoids the need for urethral catheterization (currently required to reliably determine the presence of VUR), and which thus avoids the anxiety of parents and patients that causes many families to refuse such evaluation.

Patients and methods Fifty‐four children (49 girls and five boys, mean age 7.2 years, range 4–14) previously evaluated as having VUR volunteered to participate; no child was symptomatic at the time of the study. Refluxing units were known to be present by voiding cysto‐urethrography (within 1 year, mean …