Medical Specialties Commons^™

Comparison Of Loss Of Resistance Syringe Technique Versus Balloon Technique For Identification Of Epidural Space: A Prospective, Randomized Controlled Study, Isha Singha, Gayatri Vadaratti, R.D. Patel

Journal of Medicine in Scientific Research

Context Epidural anaesthesia has an important role in modern anaesthetic practice due to its safety and efficacy, and its success depends on the technique used for identification of epidural space. Aims: In this study we compared the of loss of resistance (LOR) technique versus the balloon technique for identification of the epidural space in terms of number of attempts and time taken. Also the efficacy of the two techniques in the hands of experienced and inexperienced anaesthesiologists was compared and complications noted. Settings and design Tertiary care hospital. A prospective randomized controlled study. Methods and material 164 ASA I and …

Comparative Assessment Of The Efficacy Of Onabotulinumtoxina As Monotherapy And Combined Therapy With Propiverine In Female Refractory Overactive-Bladder Syndrome, Abourjila A. Gamal Eldin, Ayman M. Gabr, Amr M. Elsofy

Journal of Medicine in Scientific Research

Objectives The aim of the study was to compare the efficacy of onabotulinumtoxinA and anticholinergic popeverine in adult females. This is a placebo-controlled study. Introduction The active ingredient, propiverine hydrochloride, blocks muscarinic receptors with a slightly higher affinity for the M3 as compared with the M2 subtype. In addition, it inhibits calcium influx and modulates intracellular calcium in the bladder smooth-muscle cells, which then leads to musculotropic spasmolysis. Patients and methods Between 2015 and 2019, 94 patients received intravesical onabotulinumtoxinA for the treatment of refractory idiopathic detrusor overactivity after its introduction into the Department of Urology of our National Institute …

Vestibular Assessment In Patients With Temporomandibular Joint Dysfunction Attending Otolaryngology And Oral Medicine Outpatient Clinics, Sanaa Mahran Mohamed Andeil, Zienab Shalaby Farid Shalaby, Anwar Moawad Elbatawy

Journal of Medicine in Scientific Research

Introduction: Temporomandibular joint dysfunction (TMD) is caused by inflammation of the ligaments and muscles surrounding the joints. TMD is associated with several comorbidities, one of these comorbidities are otological problems. The otological symptoms related to TMD are tinnitus, otalgia, ear fullness, and Vertigo. Vertigo is observed in many diseases and etiologic factors should be investigated to increase the efficiency of treatment Objective Here we assess VNG and cVEMP findings in patients with TMD via objective vestibular testing tools including VNG and cVEMP recordings. Here, we compare findings of cervical vestibular evoked myogenic potentials (cVEMP) and of the caloric test, to …

Incidence And Severity Of Pulmonary Hypertension Among Patients With Chronic Kidney Disease, Mamdouh Maher

Journal of Medicine in Scientific Research

Chronic kidney disease (CKD) is a major health problem and is closely linked with cardiovascular disease. Pulmonary hypertension (PH) is considered a common comorbidity in CKD patients. In all, 100 patients were included in our study. Transthoracic echo Doppler study was performed to measure pulmonary artery systolic pressure based on tricuspid jet. The prevalence of PH in CKD patients in our study was 60%; prevalence and severity had significant association.

The hemodialyzed group showed a higher prevalence of PH with a more severe PH.

Our study had provided evidence that PH is a common comorbidity in CKD patients and is …

The Predictive Ability Of Interleukin-6 For Infection After Major Surgery, Naser T. Elshamy, Salama M. Elshennawy, Mahmoud A. Donia

Journal of Medicine in Scientific Research

Objective The aim was to evaluate the role of interleukin (IL)-6 in prediction of infection after major surgeries. Background An early sensitive and specific marker for postoperative infection would be of interest. The cytokines such as IL-6 and IL-10 have been shown to relate to the severity of postoperative sepsis and patient outcome. Patients and methods The study was conducted prospectively at Shebin Elkom Teaching hospital in the period from January 2015 to October 2016 on 50 consecutive patients undergoing elective major surgical procedures. Septic complications were recorded for 4 days postoperatively. For evaluation, patients were allocated into two groups …

Auditory Temporal Processing Abilities In Patients With Diabetes Mellitus Type 1 And Type 2, Abir Omara, Sanaa Mahran, Heba Ramadan

Journal of Medicine in Scientific Research

Introduction: Diabetes mellitus is most common chronic disease characteristic by carbohydrate metabolic disorder in which absolute or relative deficiency in insulin and various pathological changes in the body system. The central nervous system disorders is among system affected by toxic effect and hyperglycemia. Auditory temporal processing is one of the important abilities of the central nervous system which may be affected by diabetes. However, the extent and nature of the central manifestations are still unknown. Objective: The aim of this study was to compare auditory temporal processing in these patients (Diabetics type 1 and Type 2) with normal subjects through …

Prediction Of Response To Disease-Modifying Therapy In Multiple Sclerosis, Abdelrahman M. Abdalla, Azza Abd El-Nasser, Mohamed Fouad, Mahmoud S. Swelam

Journal of Medicine in Scientific Research

Background Multiple sclerosis is an idiopathic inflammatory disease of the central nervous system and the second most common cause of disability in young adults. Choosing an effective treatment is crucial to preventing disability. Aim To identify predictors of disease-modifying therapy (DMT) after 1 year of treatment. Patients and methods In this retrospective study, 150 patients with confirmed diagnosis of relapsing-remittent multiple sclerosis were recruited from the MS Unit at the Neurology Departments from both Ain-Shams University and Cairo University Student Hospital. All of the study population received either interferons or fingolimod. Modified Rio score was used to classify patients to …

An Analytical Study Of The Risk Factors Affecting The Platelet Aggregation In Patients With Sepsis, Vishnu Priya, Jitender M. Khunger, Anupma Arora

Journal of Medicine in Scientific Research

Objectives (a) To determine the correlation of platelet count and aggregation with sepsis severity and (b) to find the risk factors affecting the platelet aggregation in sepsis. Patients and methods The present observational cross-sectional study was conducted on 30 patients of sepsis over a period of 18 months. All patients underwent complete blood counts, and platelet aggregation to ADP. Pearson correlation coefficient was used to assess the association of Sequential Organ Failure Assessment (SOFA) score and aggregation to ADP and platelet. Linear regression was done to determine the risk factors affecting platelet aggregation in sepsis. A P value of less …

Comparative Study Between Radiofrequency Ablation And Endovenous Laser Ablation In The Management Of Primary Great Saphenous Varicose Veins, E.M Reem, H.T Ahmed, A.A Mohammed, H.A Mohamed

Journal of Medicine in Scientific Research

Background: Varicose veins are a common presentation of chronic venous disease. Multiple risk factors have been specified by epidemiological studies such as female sex, pregnancy, obesity, and prior deep venous thrombosis. Objective This is a prospective, comparative study to compare radiofrequency (RF) ablation versus endovenous laser ablation (EVLA) in the management of primary varicose veins of great saphenous vein (GSV). Patients and methods This study was conducted to 130 patients who had primary great saphenous varicose veins who attended to the vascular department of Ain Shams University Hospitals and El-Sahel Teaching Hospital. The study is a prospective comparative clinical trial. …

A Comparison Of Robotically Assisted Needle Guidance Via The Piga Ct System And Conventional Ct For Percutaneous Lung Biopsies, Virender Malik, K Uday Bhanu, Dhanalakshmi B

Journal of Medicine in Scientific Research

Objective

The aim was to compare the speed, radiation exposure, needle adjustments, diagnostic efficacy, and complication rate using manual guidance and robotically assisted needle guidance via the PIGA computed tomography (CT) system for percutaneous lung biopsy.

Methods

A randomized interventional trial was conducted from September 2020 to March 2021 on 30 patients requiring lung biopsies for suspected malignancy. Random allocation of the 30 patients was done in group A (robot-assisted CT scan) and group B (conventional manual CT scan). The outcomes were compared with respect to the total procedural duration, time taken in the navigation of needle insertion, needle manipulations, …

Histomorphological Spectrum Of Ovarian Neoplasms In A Tertiary Care Centre, Lionel Rohit Mathew, Shalini Karthikeyan, Jaishree Tamilmani, Prema Devi Elangovan, Sridevi Vijayasankar

Journal of Medicine in Scientific Research

Introduction: Ovary is the second most common site of gynaecological malignancies in India and therefore ovarian tumours need to be studied under the microscope for accurate diagnosis and management.

Aim: This study aims to study the spectrum of ovarian tumours and calculate their incidence and age-distribution. Materials and Methods: This study was conducted in the Department of Pathology, Sri Muthukumaran Medical College, Hospital & Research Institute, Chennai, during the year 2022. Results: Among a total of 68 ovarian neoplasms studied, benign tumours (61.7%) were more common and most of the patients were in the fourth decade of life. The commonest …

Outcome Of Suture Annuloplasty (De Vega) Versus Ring Annuloplasty For Functional Tricuspid Valve Regurgitation Concomintant With Mitral Valve Surgery, Tarek Elshazly Omran, Ashraf Zahra

Journal of Medicine in Scientific Research

Background: The optimal surgical technique for functional tricuspid regurgitation (TR) repair is still a topic for ongoing research. The DeVega technique is still used frequently in developing countries. Thus, this study aimed to compare the outcomes of tricuspid valve repair using DeVega vs. ring annuloplasty for managing severe functional TR during mitral valve surgery. Methods: This retrospective chart review included 66 patients. The study included patients with simultaneous tricuspid valve repair during mitral valve intervention. The patients were recruited from 2018 to 2022. The study had two groups: the first group included 50 patients who underwent the DeVega technique (Group …

Comparative Study Between Torsional Phacoemulsification And Longitudinal Phacoemulsification In Their Effect On Corneal Endothelium Using Specular Microscopy., Tarek Ibrahim Badr

Journal of Medicine in Scientific Research

Background The cornea is formed of 5 layers, Endothelium is that most posterior layer which is responsible for keeping cornea dehydrated. Loss of corneal endothelium is a sideeffect of many cataract surgeries that may influence postoperative visual outcome of the patients. Our study aims to compare torsional phacoemulsification and longitudinal phacoemulsification in their effect on corneal endothelium using specular microscopy. Patients and Methods We will compare the corneal endothelium parameters (central density of cells & cell loss, alterations in shape & size) afterward torsional phacoemulsification and longitudinal phacoemulsification in this prospective randomized study. 50 eyes with nuclear cataracts in grades …

Natural Cycle Versus Stimulated Or Artificial Cycle In Frozen–Thawed Embryo Transfer: A Randomized Prospective Trial, Salwa H.B. El-Wakil, Naglaa M. Moharam, Ahmed G.A. El-Seuror

Journal of Medicine in Scientific Research

Objective The goal of this study was to see if there was a difference in pregnancy outcomes between natural cycle frozen–thawed embryo transfer (NC-FET) cycles, artificial cycle–FET cycles, and stimulated cycle (SC)–FET cycles in women with regular menstrual cycles. Patients and methods This prospective randomized clinical study was conducted in Assisted Reproductive Unit (ART), The International Islamic Center for Population Studies and Research, El Hussein Hospital, Al-Azhar University, in the period of September 2019 till August 2020. Results There was a significant increase in immotile sperms in the natural group (P=0.014). Group I had much lower total count and total …

Yersinia Infection In Acute Appendicitis In Children In Shebin Elkom Teaching Hospital, Salama M. El- Shennawy, Khaled S.A. Elkelany, Mariam A. Fouad, Shimaa M.M Bebars, Faisel Goda, Abdelghany Abdelsattar Aish

Journal of Medicine in Scientific Research

Background: Yersinia enterocolotica is being recognized as an important bacterial cause of acute gastrointestinal infection. The association of yersinia entrocolotica infections with acute appendicitis has been suggested (Tae Joon Son et. al, 2009). The aim to ascertain whether yersinia entrocolotica is a possible infectious agent in appendicitis in Shebin Elkom. We try to support or to deny this suggestion. Methods: A prospective randomized study was done to 48 patients admitted to surgical department from outpatient clinic of Shebin Elkom Teaching Hospital over 14 months from January 2020 to March 2021The purpose and nature of the study were explained to all …

Editorial: Pulsed Electric Field Based Technologies For Oncology Applications, Siqi Guo, Gregor Sersa, Richard Heller

Bioelectrics Publications

No abstract provided.

Implementation Of Patient-Centered Care By Athletic Training Students During Clinical Experiences: A Report From The Association Of Athletic Training Education Research Network, Julie M. Cavallario, Bonnie L. Van Lunen, Stacy E. Walker, R. Curtis Bay, Cailee E. Welch-Bacon

Rehabilitation Sciences Faculty Publications

Patient-centered care (PCC) is a core competency that should be required by all healthcare education programs, but little is known about its implementation in athletic training clinical experiences. Therefore, we examined characteristics of patient encounters documented by athletic training students implementing PCC behaviors. A multisite panel design was used to recruit 363 students from twelve professional athletic training programs (five undergraduate, seven graduate). Over 1.5 years, clinical experience patient encounter data were logged in E*Value Case Logs, including student role during the encounter, length of encounter, and clinical site. Generalized estimating equations models characterized the likelihood students included PCC behaviors …

Should Near Systemic Pulmonary Hypertension Be A Contraindication For Rheumatic Mitral Stenosis Valve Surgery In Egyptian Population?, Ahmed Mostafa Omran, Hany Fayed

Journal of Medicine in Scientific Research

Background: pulmonary hypertension is a well known risk factor leading to mortality and morbidity in Mitral stenosis patients, in spite of long term outcome are being comparable regarding severe and mild or moderate pulmonary hypertension but definitely short term results are worse.

Objective: new management protocol to decrease the immediate postoperative differences between patients having Mitral stenosis with near systemic pulmonary hypertension compared to patients with mild or moderate pulmonary hypertension.

Patients and Methods: Prospective cohort single centre study was held in National heart institute, between 2016 and 2022, on patients undergoing Mitral valve surgery for Mitral stenosis with near …

Expression Levels Of Matrix Metalloproteinase 2 Protein In Preinvasive And Invasive Cervical Lesions And Its Clinicopathological Association: A North Indian Study, Rekha Sachan, Pushp L. Sachan, Ayushi Shukla, Malti Maurya, Munna L. Patel

Journal of Medicine in Scientific Research

Background Matrix metalloproteinase (MMPs) play an important role in development of female genital cancers and metastasis. The aim of this study was to analyze expression levels of MMP2 in various grades of cervical intraepithelial neoplasia (CIN) and squamous cell carcinoma (SCC) of cervix and its association with clinicopathological variables. Patients and methods This prospective study was carried out in a tertiary care center in Northern India over a period of 1 year. A total of 664 participants with gynecological complaints and unhealthy cervix were recruited for colposcopy. Of these, 70 biopsy samples were obtained from higher grade colposcopy lesions, where …

Standard Median Sternotomy Versus Minimally Invasive Approach For Atrial Septal Defect Closure In Adults, Ahmed S. Ali, Ahmed G. Abd El Fattah Fahmy, Hatem K. Madkour, Reham M. Salah Eldin Ahmed

Journal of Medicine in Scientific Research

Background

Atrial septal defects (ASDs) in adults and adolescents are not uncommon. Surgical ASD closure through a standard median sternotomy (SMS) has become less attractive approach in favor of minimally invasive techniques, especially in young female patients.

Objective

The aim was to compare early postoperative outcomes of surgically closed secundum ASDs through a SMS approach versus minimally invasive right anterolateral thoracotomy (MIRAT) approach in adults.

Patients and methods

The authors prospectively studied 60 adult patients who had their secundum ASD anomalies surgically closed at National Heart Institute between the period of September 2020 and February 2022. A total of 30 …

Molecular Detection Of Entamoeba Histolytica In Diarrheic Fecal Samples From Patients Attending National Hepatology And Tropical Medicine Research Institute, Azza Hasan Abbas, El Shahat Ahmed Elshahat, Heba Mohamed Abdelglil

Journal of Medicine in Scientific Research

Background: Amoebiasis is a worldwide disease caused by Entamoeba histolytica infection. The true prevalence is unknown due to the difficulty in distinguishing Entamoeba histolytica from non-pathogenic amoebas especially when microscopic diagnosis is performed, to overcome microscopy misidentification. Polymerase Chain Reaction (PCR) assay is necessary as a highly sensitive and specific technique. Objective: To determine the value of Real-Time PCR (RT.PCR) in the diagnosis of Entamoeba histolytica in the stool samples of diarrheic patients attending NHTMI versus microscopy, copro- antigen, and serum antibodies detection techniques. Subjects and Methods: A cross-sectional study was conducted on 150 diarrheic patients. Their stool samples were …

The Immune Response To Long Term Administration Of Dipravan Compare To Dormicum In Surgical Care Unit, Ashraf Abd El Hameed Soliman, Wael Abd Elateif El Hakeem, Raghad S. Abdellatif

Journal of Medicine in Scientific Research

Introduction : - Immune response may be affected by anesthesia and sedation. In anesthesia, the immue response is temporary as anesthesia is used for short time. However, the immune response more obvious in critical illness patients because of long time of sedation. Diprivan and dormicum are two commonly used medications for sedation and analgesia in critical care unit patients. Dipravan is a good medication for sedation in the surgical care unit. Dormicum in the surgical care unit, usually producing prolonged time of sedation when used for long time in surgical care unit. Patients and methods: - This article was done …

The Relation Between Heart Rate Response During Exercise And Angiographic Severity In Patients With Chronic Coronary Syndrome, Emmanuel Louka

Journal of Medicine in Scientific Research

Introduction Ellestad and colleagues, in 1975, reached to the conclusion that impaired heart rate response to exercise carries a similar risk for future coronary events such as ischemic ‘ST’ segment changes. Mc Neer and colleagues went beyond these observations to include a survival benefit in patients who achieve a higher peak heart rate (PHR), a more advanced level of exercise, and have a normal exercise electrocardiogram. Aim The aim of this work is to clarify the relation between the chronotropic response to exercise and the severity of coronary artery disease in patients with chronic coronary syndrome. Patients and methods The …

Dental And Oral Manifestations Of Rheumatoid Arthritis: Is It Related To General Disease Activity?, Omnia A. Abubakr, Ali M Youssef, Mohamed A Mohamed, Mohamed A Hamdy

Journal of Medicine in Scientific Research

Background: RA is a chronic immune-mediated systemic disorder; its pathogenesis is complex. Genetic, environmental, hormonal, and lifestyle are the main risk factors. The correlation between oral health and RA is rising. Oral manifestations in RA include temporomandibular joint disorder, secondary Sjögren’s syndrome, xerostomia, and periodontal disease. Previous studies suggest a bidirectional relationship between RA and periodontal diseases. This study aims to detect oral mucosal and dental disease in RA patients and its relation to demographic features, disease activity, and extra-articular manifestation. Patients and Methods: This cross-sectional study included 150 patients with RA allocated into two groups, 75 patients in each …

Comparative Study Between Intravenous Anesthesia (Propofol) And Inhalational Anesthesia (Sevoflurane) On The Cytokine’S Response To Abdominal Operation, Ashraf A.H. Mahmoud Soliman, Maisa M. Abdel Khalik, Wael A.E. El Hakeem, Raghad S. Abdellatif

Journal of Medicine in Scientific Research

Introduction These days, the need for more information and familiarity with the inflammatory response to different anesthetic drugs increase. Not only some patients suffering from immune reactions against some anesthetic drugs, but all surgical patients are liable to decrease in immunity postoperatively. This may increase the postoperative morbidity and mortality, affects healing, and spread of tumors postoperatively. This decrease in immunity is due to surgery trauma causing imbalance in cytokine response. Patients and methods This article was written on 40 patients, and patients were randomly classified into four equal classes. Class A: inhalational anesthesia on major operation. Class B: intravenous …

Angiotensin I-Converting Enzyme Insertion/Deletion Gene Polymorphism And Its Association With Diabetic Nephropathy In Type-2 Diabetes Mellitus Patients: An Egyptian Study, Yasmine M. Amrousy, Tamer M. Soliman, Haythem A. Tolba, Aisha Elshimy

Journal of Medicine in Scientific Research

Background Diabetic nephropathy (DN) is one of the most serious complications associated with type-2 diabetes mellitus (T2DM). With variable allele and genotype frequencies, the angiotensin I-converting enzyme (ACE) insertion–deletion (I/D) gene polymorphism has been suggested as a risk factor for DN. Objective The purpose of the study was to find whether ACE I/D polymorphism is associated with DN in Egyptian T2DM patients and its relation to ACE concentration and C-reactive protein quantitative level. Participants and methods A case–control study of 98 T2DM patients was divided into two groups: group 1, T2DM patients without DN, and group 2, T2DM patients with …

Effectiveness Of Management Program Of Chronic Functional Constipation In Children Who Are Attending The Pediatric Gastroenterology Clinic At Elbeheira Specialized Children's Hospital, Hamouda E. El-Gazzar, Sabreen Ahmed Ali Elsaka, Eman Adel Elsaid Elhaddad

Journal of Medicine in Scientific Research

Background: A chronic constipation is one of the most common functional gastrointestinal complaints in pediatric outpatient clinics. The prevalence of childhood constipation in the general population ranges widely from 0.7% to 29.6% internationally. Pediatric Gastroenterology Clinic at Elbeheira specialized children's Hospital is a referral center from the whole governorate. Objectives: To evaluate the current approach to management, risk factors associated, and clinical characteristics, the challenge of functional constipation in the pediatrics who are attending the Pediatric Gastroenterology Clinic at Elbeheira Specialized Children's Hospital. Methods: This retrospective study was conducted in Pediatric Gastroenterology Clinic at Elbeheira Children's Specialized Hospital for 6 …

Endovascular Management Of Vein Of Galen Aneurysmal Malformations: Case Series And Review Of The Literature, Mohammed A. El-Din Habiba, Sameh M. Saleh

Journal of Medicine in Scientific Research

Background Neonates with vein of Galen aneurysmal malformations (VGAMs) who present with heart failure have a high rate of morbidity and mortality, while those who present later in childhood have considerably better outcomes. Aim To determine the factors that have the greatest predictive value in predicting long-term results in children with VGAM. Patients and methods Between June 2015 and June 2020, 15 patients (seven infants, eight children) were diagnosed with symptomatic VGAMs, four of whom were suffering from intractable high-output heart failure and received initial endovascular treatment. All of them were treated by endovascular procedures. Staged transarterial route was the …

Different Modalities Of Tongue Tie Management, Wesam Ibrahem Homouda, Esayed Hussien Elmokadem, Mohamed Amr Hamdy Salem

Journal of Medicine in Scientific Research

Background: Tongue-tie or ‘ankyloglossia’ is a congenital anomaly characterized by presence of an abnormally tight lingual frenulum - a string like membrane – that attaches the tongue to the floor of the mouth. It affects the movement of the tongue. For symptomatizing ankyloglossia surgical treatment with different surgical techniques such as (Frenotomy, frenectomy/frenulectomy, and frenuloplasty) is the treatment of choice that gives satisfactory results. Objectives: We built our study to compare between different surgical techniques used for management of ankyloglossia. Patient and method: in our study 60 patients were included 33 were female and 27 were male with age ranging …

A Case Of Congenital Diaphragmatic Hernia Presenting In The Adult As Gastric Volvulus, Sajal Gupta, Ismail Khan, Indu B. Dubey, Mayank Verma

Journal of Medicine in Scientific Research

We report a case of an adult patient who was referred to the surgical emergency for the evaluation of acute abdominal pain and vomiting. Radiograph chest showed a left-sided cavity, which was misleading to lung pathology. A suspicion of gastric volvulus was kept in mind on seeing the stomach in the radiograph. Computed tomography confirmed the diagnosis of diaphragmatic hernia. The insertion of the Ryle’s tube corrected the gastric volvulus. An immediate laparotomy was done for the closure of the diaphragmatic gap and reduction of the herniated contents. The patient responded well and was discharged in a week.