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Articles 28501 - 28530 of 77178

Full-Text Articles in Medical Specialties

Lacrimal Gland Epithelial Cells Shape Immune Responses Through The Modulation Of Inflammasomes And Lipid Metabolism, Vanessa Delcroix, Olivier Mauduit, Menglu Yang, Amrita Srivastava, Takeshi Umazume, Cintia S De Paiva, Valery I Shestopalov, Darlene A Dartt, Helen P Makarenkova Feb 2023

Lacrimal Gland Epithelial Cells Shape Immune Responses Through The Modulation Of Inflammasomes And Lipid Metabolism, Vanessa Delcroix, Olivier Mauduit, Menglu Yang, Amrita Srivastava, Takeshi Umazume, Cintia S De Paiva, Valery I Shestopalov, Darlene A Dartt, Helen P Makarenkova

Faculty, Staff and Students Publications

Lacrimal gland inflammation triggers dry eye disease through impaired tear secretion by the epithelium. As aberrant inflammasome activation occurs in autoimmune disorders including Sjögren's syndrome, we analyzed the inflammasome pathway during acute and chronic inflammation and investigated its potential regulators. Bacterial infection was mimicked by the intraglandular injection of lipopolysaccharide (LPS) and nigericin, known to activate the NLRP3 inflammasome. Acute injury of the lacrimal gland was induced by interleukin (IL)-1α injection. Chronic inflammation was studied using two Sjögren's syndrome models: diseased


It Is Not Pneumocystis Jiroveci (Pcp), It Is Cyclophosphamide-Induced Pneumonitis, Mery Bartl, Yilen Karen Ng-Wong, Blesset Alexander, Jose Gomez Casanovas, Josenny L. Rodriguez-Paez, Andres Suarez, Christine Loftis Feb 2023

It Is Not Pneumocystis Jiroveci (Pcp), It Is Cyclophosphamide-Induced Pneumonitis, Mery Bartl, Yilen Karen Ng-Wong, Blesset Alexander, Jose Gomez Casanovas, Josenny L. Rodriguez-Paez, Andres Suarez, Christine Loftis

School of Medicine Publications

Cyclophosphamide (CYC) is an immunosuppressive medication used to treat life-threatening complications of various rheumatic diseases like vasculitis and systemic lupus erythematosus. A rare side effect of this medication is pneumonitis, which occurs in less than 1% of patients. We describe a case of an 83-year-old woman with a past medical history of microscopic polyangiitis, who presented with progressive dyspnea at rest, exacerbated on exertion, and associated with orthopnea that was attributed to CYC-induced pneumonitis. Three months before this presentation, the patient was diagnosed with antineutrophil cytoplasmic antibodies (ANCA)-positive pauci-immune crescentic and necrotizing glomerulonephritis and started on CYC. On admission, a …


Comparison Of Dna Extraction Methods For Soft Tissue Samples, Steve Guzman, Nathaniel E. Hill, Mujtaba Shah, Jonathon Reynolds, Cole Farnsworth, Molly Henley, Alfred Amendolara, Laura Minor, John Dougherty Jr., John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Comparison Of Dna Extraction Methods For Soft Tissue Samples, Steve Guzman, Nathaniel E. Hill, Mujtaba Shah, Jonathon Reynolds, Cole Farnsworth, Molly Henley, Alfred Amendolara, Laura Minor, John Dougherty Jr., John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Vitamin C Contributes To Epigenetic Regulation Of Genes Related To Diabetic Retinopathy In Retinal Endothelial Cells, Elizabeth L. Turner, Jonathon Reynolds, Walker Kay, Marianne Becnel, Matthew Conway, Alexander Kim, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


Determination Of Feasibility And Plausibility Of Using Various Biological Samples For Remote Genetic Testing, Cole Farnsworth, Molly Henley, Walker Kay, Varos Victer Manukyan, Jonathon Reynolds, John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Determination Of Feasibility And Plausibility Of Using Various Biological Samples For Remote Genetic Testing, Cole Farnsworth, Molly Henley, Walker Kay, Varos Victer Manukyan, Jonathon Reynolds, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


Development Of An Affordable, Manual Method Of Dna Extraction From Bones And Teeth ​, Varos Victer Manukyan, Lara Laughrey, Ryan V. Powers, Amar Paul, Davis Johnston, Dashon Eure, Todeh Toomians, John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Development Of An Affordable, Manual Method Of Dna Extraction From Bones And Teeth ​, Varos Victer Manukyan, Lara Laughrey, Ryan V. Powers, Amar Paul, Davis Johnston, Dashon Eure, Todeh Toomians, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


Breast Cancer Subtyping Of The Cancer Genome Atlas (Tcga) Samples, Spencer E. Yu, Alfred B. Amendolara, Steven T. Tung, Alexander P. Sheppert, Nasif Islam, Mindy Cook, Lena Diprizito, Nicole Lashiker, Roshni Jogin, John A. Kriak, Kyle B. Bills, David W. Sant Feb 2023

Breast Cancer Subtyping Of The Cancer Genome Atlas (Tcga) Samples, Spencer E. Yu, Alfred B. Amendolara, Steven T. Tung, Alexander P. Sheppert, Nasif Islam, Mindy Cook, Lena Diprizito, Nicole Lashiker, Roshni Jogin, John A. Kriak, Kyle B. Bills, David W. Sant

Annual Research Symposium

No abstract provided.


The Immunomodulating Effects Of Morphine Dependence And Withdrawal In Rat Lung, Liver, Spleen And Blood, Yensi Munoz Feb 2023

The Immunomodulating Effects Of Morphine Dependence And Withdrawal In Rat Lung, Liver, Spleen And Blood, Yensi Munoz

Annual Research Symposium

No abstract provided.


The Immunomodulating Effects Of Morphine Dependence And Withdrawal In A Rat Model, Mark Stoll Feb 2023

The Immunomodulating Effects Of Morphine Dependence And Withdrawal In A Rat Model, Mark Stoll

Annual Research Symposium

Would you like to know what happens to the immune system during opioid drug withdrawal?


Anti-Diabetic Drug, Semaglutide, Prevents Doxorubicin-Induced Cardiotoxicity, Sandra Bakhit, Kota Ramana Feb 2023

Anti-Diabetic Drug, Semaglutide, Prevents Doxorubicin-Induced Cardiotoxicity, Sandra Bakhit, Kota Ramana

Annual Research Symposium

No abstract provided.


Carvacrol Regulates Endotoxin -Induced Arachidonic Acid Metabolism., Aliea M. Jalali, Spencer Norton Feb 2023

Carvacrol Regulates Endotoxin -Induced Arachidonic Acid Metabolism., Aliea M. Jalali, Spencer Norton

Annual Research Symposium

Plant-derived essential oil prevents endotoxin-induced inflammatory response


A Systematic Review: Toxoplasma Gondii Infection And Drugs Of Abuse, Amani Sastry Feb 2023

A Systematic Review: Toxoplasma Gondii Infection And Drugs Of Abuse, Amani Sastry

Annual Research Symposium

No abstract provided.


The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor Feb 2023

The Current State Of Underrepresented Osteopathic Minorities In Competitive Specialties, Emmanuel Oyalabu, Steve Guzman, Dashon Eure, Ezenna Obilor

Annual Research Symposium

It is well documented that barriers exist for underrepresented minorities to enter the field of medicine and even more competitive residencies. As defined by the NRMP, competitive specialties include but are not limited to Interventional Radiology, Orthopedic Surgery, Plastic Surgery, Radiation Oncology, Vascular Surgery, Neurosurgery, Dermatology, and Otornylogy (NRMP-AMA). A large number of osteopathic medical school graduates have a history of going into primary care specialties because many osteopathic medical schools have a primary care focus (Primary Care- Osteopathic Medicine). The emphasis on primary care, whether intentional or not, can foster a less-than-advantageous environment for underrepresented minority students (URM), pursuing …


Evaluation Of Dexamethasone Premedication Prescribing For Docetaxel, Kianna Boc Feb 2023

Evaluation Of Dexamethasone Premedication Prescribing For Docetaxel, Kianna Boc

Annual Research Symposium

No abstract provided.


Appearance Of Two Distinct Clusters Of Glucose Dysregulation In Chronic Intractable Migraine, Roshni Jogin, Kaitlyn Mcfarland, Aparna Naik, Tanner Williford, Matthew Conway, Amar Paul, John A. Kriak, David W. Sant, Kyle B. Bills Feb 2023

Appearance Of Two Distinct Clusters Of Glucose Dysregulation In Chronic Intractable Migraine, Roshni Jogin, Kaitlyn Mcfarland, Aparna Naik, Tanner Williford, Matthew Conway, Amar Paul, John A. Kriak, David W. Sant, Kyle B. Bills

Annual Research Symposium

No abstract provided.


Heterodyned Whole-Body Vibration Ameliorates Anxiety In Opioid-Use Disorder, Kailee Edwards, Braden Cunningham, Alfred Amendolara, Marryam Anwar, Jon Gonzales, Roshni Jogin, Wyatt Magoffin, Amar Paul, Ryan Perry, James Pike, Nathan Swallow, Steven Tung, Mary Seamons, Andrew Payne, John A. Kriak, David W. Sant, David W. Sant Feb 2023

Heterodyned Whole-Body Vibration Ameliorates Anxiety In Opioid-Use Disorder, Kailee Edwards, Braden Cunningham, Alfred Amendolara, Marryam Anwar, Jon Gonzales, Roshni Jogin, Wyatt Magoffin, Amar Paul, Ryan Perry, James Pike, Nathan Swallow, Steven Tung, Mary Seamons, Andrew Payne, John A. Kriak, David W. Sant, David W. Sant

Annual Research Symposium

No abstract provided.


Development Of A Neural Network Model To Identify Abnormalities In Cervical X-Rays, Alex P. Sheppert, Nasif Islam, Race Peterson, Michael T. Sullivan, John A. Kriak, David W. Sant, Kyle B. Bills Feb 2023

Development Of A Neural Network Model To Identify Abnormalities In Cervical X-Rays, Alex P. Sheppert, Nasif Islam, Race Peterson, Michael T. Sullivan, John A. Kriak, David W. Sant, Kyle B. Bills

Annual Research Symposium

No abstract provided.


Planning A Review Of The Pathogenesis And Management Of Valley Fever, Seattle Shakur Feb 2023

Planning A Review Of The Pathogenesis And Management Of Valley Fever, Seattle Shakur

Annual Research Symposium

No abstract provided.


Clinical Trial Subject Recruitment: Research Immersion Experience, Brooklyn Janes Feb 2023

Clinical Trial Subject Recruitment: Research Immersion Experience, Brooklyn Janes

Annual Research Symposium

No abstract provided.


Staff At Increased Risk For Computer Vision Syndrome Compared To Faculty At An Osteopathic Medical School With An Electronic Content Delivery Model, Joseph Bachman Feb 2023

Staff At Increased Risk For Computer Vision Syndrome Compared To Faculty At An Osteopathic Medical School With An Electronic Content Delivery Model, Joseph Bachman

Annual Research Symposium

No abstract provided.


Serdexmethylphenidate/Dexmethylphenidate – A Promising Treatment Option For Childhood Attention Deficit Hyperactivity Disorder (Adhd), N Troy To, H Stephen Lee Feb 2023

Serdexmethylphenidate/Dexmethylphenidate – A Promising Treatment Option For Childhood Attention Deficit Hyperactivity Disorder (Adhd), N Troy To, H Stephen Lee

Annual Research Symposium

To review the phase 2 and phase 3 clinical trials of Serdexmethylphenidate and dexmethylphenidate (SDX/d-MPH) in the treatment of Attention Deficit/Hyperactivity disorder (ADHD) in children.


Sulopenem For The Treatment Of Complicated And Uncomplicated Bacterial Urinary Tract Infection (Uti), Aiyi Chen, Thanh-Liem Vu, Daniel J. Yang, Landon Olsen Feb 2023

Sulopenem For The Treatment Of Complicated And Uncomplicated Bacterial Urinary Tract Infection (Uti), Aiyi Chen, Thanh-Liem Vu, Daniel J. Yang, Landon Olsen

Annual Research Symposium

No abstract provided.


Eflapegrastim-Xnst: A New Agent To Prevent Antineoplastic Chemotherapy-Induced Febrile Neutropenia, Gary Lynch Feb 2023

Eflapegrastim-Xnst: A New Agent To Prevent Antineoplastic Chemotherapy-Induced Febrile Neutropenia, Gary Lynch

Annual Research Symposium

No abstract provided.


Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes Feb 2023

Focus Group Interview Experience Of A University Clinical Research Team, Kade Janes

Annual Research Symposium

No abstract provided.


Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane Feb 2023

Development Of A Census Driven Equation To Predict Non-Billable "Cross-Cover" Work Done During Nocturnist Shifts To Predict Staffing, Bibhash Neupane

Annual Research Symposium

No abstract provided.


Assessment Of Nutrition Care Needs In The Management Of Pediatric Patients With Rare Disease, Elizabeth Turner, Kayla Woodring, Marianne Becnel, Saisha Kataria, Esther Nuebel Feb 2023

Assessment Of Nutrition Care Needs In The Management Of Pediatric Patients With Rare Disease, Elizabeth Turner, Kayla Woodring, Marianne Becnel, Saisha Kataria, Esther Nuebel

Annual Research Symposium

2023 Roseman University Research Symposium: Poster Session


Roseman Research Symposium, Manas Mandal Feb 2023

Roseman Research Symposium, Manas Mandal

Annual Research Symposium

No abstract provided.


Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr. Feb 2023

Emergence Of Dental Nanomaterials: “Their Role In Performing Endodontic Therapy”, Chandrika Nama, John Wisniewski Dr.

Annual Research Symposium

No abstract provided.


The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang Feb 2023

The Impact Of A Hospital Protocol In Neonates At Risk For Neonatal Abstinence Syndrome (Nas), Victoria Pang

Annual Research Symposium

No abstract provided.


New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal Feb 2023

New Year, New Variant Or A Subvariant Of Old Omicron?, Parker Grossman, Manas Mandal

Annual Research Symposium

No abstract provided.